full name
mediator complex subunit 12
synonyms
ARC240, CAGH45, FGS1, HOPA, MED12S, OHDOX, OKS, OPA1, TNRC11, TRAP230, MED12, ENSG00000184634
HGNC
HGNC:11957
Entrez Gene
Gene:9968
ENSEMBL
ENSG00000184634
location
chr: X
start: 70338406
stop: 70362304
strand: +
OMIM
OMIM:300188:
MED12
(X-linked recessive inheritance)
OMIM:309520:
Lujan-Fryns syndrome
OMIM:300895:
Ohdo syndrome, X-linked
OMIM:305450:
Opitz-Kaveggia syndrome
transcripts
NM_005120.2
pathways
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Fatty acid, triacylglycerol, and ketone body metabolism
[NCBI:1270010]
[REACTOME:R-HSA-535734]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins
[NCBI:1270001]
[REACTOME:R-HSA-556833]
PPARA activates gene expression
[NCBI:1270030]
[REACTOME:R-HSA-1989781]
[PUBMED:10529898]
[PUBMED:18288277]
[PUBMED:11330046]
[PUBMED:20936127]
[PUBMED:14999402]
Regulation of Wnt-mediated beta catenin signaling and target gene transcription
[NCBI:169352]
[Pathway Interaction Database:wnt_beta_catenin_pathway]
[PUBMED:19901072]
[PUBMED:19699733]
[PUBMED:15142975]
[PUBMED:16565090]
[PUBMED:17372190]
[PUBMED:17310985]
[PUBMED:11751639]
[PUBMED:16301527]
[PUBMED:10921920]
[PUBMED:8622675]
[PUBMED:19571879]
[PUBMED:11445543]
[PUBMED:19066453]
[PUBMED:15768032]
[PUBMED:10704849]
[PUBMED:19940019]
[PUBMED:15378020]
[PUBMED:10318916]
[PUBMED:10617567]
[PUBMED:19435523]
[PUBMED:18511409]
[PUBMED:18006687]
[PUBMED:14638683]
[PUBMED:15782138]
[PUBMED:15143193]
[PUBMED:9671490]
[PUBMED:11263497]
[PUBMED:18193033]
[PUBMED:9751710]
[PUBMED:11532957]
[PUBMED:10898789]
[PUBMED:11266540]
[PUBMED:17090534]
[PUBMED:15492215]
[PUBMED:16309666]
[PUBMED:12502739]
[PUBMED:10980707]
[PUBMED:17945188]
[PUBMED:11572874]
[PUBMED:11809808]
[PUBMED:17113388]
[PUBMED:20128690]
[PUBMED:17709391]
[PUBMED:11500377]
[PUBMED:12464179]
[PUBMED:18347071]
[PUBMED:18347094]
[PUBMED:15592430]
[PUBMED:10958684]
[PUBMED:12408825]
[PUBMED:15525529]
[PUBMED:16581771]
[PUBMED:12052822]
[PUBMED:15668231]
[PUBMED:16014379]
[PUBMED:17923689]
[PUBMED:15592505]
[PUBMED:10984057]
[PUBMED:20044351]
[PUBMED:11940574]
[PUBMED:10747853]
[PUBMED:12606575]
[PUBMED:15728254]
[PUBMED:11080158]
[PUBMED:12446687]
[PUBMED:20128911]
[PUBMED:19816403]
[PUBMED:18573912]
[PUBMED:17397822]
[PUBMED:10489374]
[PUBMED:17052462]
[PUBMED:20371816]
[PUBMED:18347063]
[PUBMED:11035805]
[PUBMED:11792709]
[PUBMED:16899215]
[PUBMED:10882123]
[PUBMED:12200448]
[PUBMED:15060161]
[PUBMED:12711682]
[PUBMED:12582159]
[PUBMED:12646922]
[PUBMED:19460168]
[PUBMED:16778892]
[PUBMED:17306568]
[PUBMED:12712206]
[PUBMED:19711354]
[PUBMED:17893322]
[PUBMED:10934025]
[PUBMED:19503085]
[PUBMED:19433865]
Regulation of lipid metabolism by Peroxisome proliferator-activated receptor alpha (PPARalpha)
[NCBI:1270029]
[REACTOME:R-HSA-400206]
[PUBMED:18288277]
[PUBMED:10529898]
[PUBMED:16476485]
[PUBMED:16503871]
Thyroid hormone signaling pathway
[NCBI:946598]
[KEGG:hsa04919]
[PUBMED:20005976]
[PUBMED:17983645]
[PUBMED:15345678]
[PUBMED:16951130]
[PUBMED:16214361]
[PUBMED:18329679]
[PUBMED:20051527]
[PUBMED:17574003]
[PUBMED:19716314]
[PUBMED:19755667]
[PUBMED:20868274]
[PUBMED:21835053]
[PUBMED:16051672]
[PUBMED:19295177]
[PUBMED:23021374]
[PUBMED:22484490]
Transcriptional regulation of white adipocyte differentiation
[NCBI:1270345]
[REACTOME:R-HSA-381340]
[PUBMED:21082419]
[PUBMED:17956727]
[PUBMED:17475546]
[PUBMED:1840554]
[PUBMED:17139329]
[PUBMED:15860371]
[PUBMED:18518822]
[PUBMED:10603305]
[PUBMED:7531665]
[PUBMED:20054179]
[PUBMED:7838715]
[PUBMED:16054042]
[PUBMED:17060461]
[PUBMED:17011499]
[PUBMED:16380219]
[PUBMED:8970730]
