full name
thyroid peroxidase

synonyms
MSA, TDH2A, TPX, TPO, ENSG00000115705

HGNC
HGNC:12015

Entrez Gene
Gene:7173

ENSEMBL
ENSG00000115705

location
chr: 2
start: 1417233
stop: 1547445
strand: +

OMIM
OMIM:606765: TPO (Autosomal recessive inheritance)
OMIM:274500: Thyroid dyshormonogenesis 2A

transcripts
NM_000547.5
NM_175719.3
NM_001206744.1
NM_001206745.1
NM_175721.3
NM_175722.3

pathways
Amine-derived hormones [NCBI:1270175] [REACTOME:R-HSA-209776] [PUBMED:10691773] [PUBMED:3297964] [PUBMED:16942634]
Autoimmune thyroid disease [NCBI:83121] [KEGG:hsa05320] [PUBMED:15132715] [PUBMED:12192541] [PUBMED:17192582] [PUBMED:9534029] [PUBMED:11396701] [PUBMED:11913070] [PUBMED:15049952] [PUBMED:11577986] [PUBMED:15762980]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Thyroid hormone biosynthesis, tyrosine => triiodothyronine/thyroxine [NCBI:413358] [KEGG:hsa_M00043]
Thyroid hormone synthesis [NCBI:835410] [KEGG:hsa04918] [PUBMED:21448409] [PUBMED:9086577] [PUBMED:21986207] [PUBMED:11137035] [PUBMED:17666482] [PUBMED:20407074] [PUBMED:20093166] [PUBMED:20122987] [PUBMED:15611820] [PUBMED:20378719] [PUBMED:23438835] [PUBMED:11717564] [PUBMED:16870170] [PUBMED:19196800] [PUBMED:9538302] [PUBMED:11029276] [PUBMED:20167242] [PUBMED:10893432] [PUBMED:21683758]
Thyroxine biosynthesis [NCBI:1270177] [REACTOME:R-HSA-209968] [PUBMED:3297964]
Tyrosine metabolism [NCBI:82959] [KEGG:hsa00350] [PUBMED:8550403] [PUBMED:1194238] [PUBMED:11171088] [PUBMED:18435614]
thyroid hormone biosynthesis [NCBI:545298] [BIOCYC:HUMAN_PWY-6241] [PUBMED:1939080] [PUBMED:12782676] [PUBMED:11396699] [PUBMED:10403182] [PUBMED:19436071] [PUBMED:16959834] [PUBMED:19179434] [PUBMED:17062880] [PUBMED:7021557] [PUBMED:19196800]