full name
UPF3B, regulator of nonsense mediated mRNA decay

synonyms
HUPF3B, MRXS14, RENT3B, UPF3X, UPF3B, ENSG00000125351

HGNC
HGNC:20439

Entrez Gene
Gene:65109

ENSEMBL
ENSG00000125351

location
chr: X
start: 118941115
stop: 118986991
strand: -

OMIM
OMIM:300298: UPF3B (X-linked recessive inheritance)
OMIM:300676: Mental retardation, X-linked, syndromic 14

transcripts
NM_023010.3
NM_080632.2

pathways
Cleavage of Growing Transcript in the Termination Region [NCBI:1269686] [REACTOME:R-HSA-109688]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Nonsense Mediated Decay (NMD) enhanced by the Exon Junction Complex (EJC) [NCBI:1269717] [REACTOME:R-HSA-975957] [PUBMED:19859661] [PUBMED:21496649] [PUBMED:17352659] [PUBMED:20795950] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17671086] [PUBMED:19410547]
Nonsense-Mediated Decay (NMD) [NCBI:1269716] [REACTOME:R-HSA-927802] [PUBMED:18524595] [PUBMED:17671086] [PUBMED:19359157] [PUBMED:17531985] [PUBMED:17352659] [PUBMED:21496649] [PUBMED:19859661] [PUBMED:20795950] [PUBMED:19010255]
Processing of Capped Intron-Containing Pre-mRNA [NCBI:1269688] [REACTOME:R-HSA-72203]
RNA Polymerase II Transcription [NCBI:1269675] [REACTOME:R-HSA-73857]
RNA Polymerase II Transcription Termination [NCBI:1269685] [REACTOME:R-HSA-73856]
RNA transport [NCBI:177876] [KEGG:hsa03013] [PUBMED:10872469] [PUBMED:17401408] [PUBMED:20733056] [PUBMED:11018020] [PUBMED:15519698] [PUBMED:16314458] [PUBMED:15901496] [PUBMED:9548260] [PUBMED:18313922]
Transport of Mature Transcript to Cytoplasm [NCBI:1269693] [REACTOME:R-HSA-72202]
Transport of Mature mRNA derived from an Intron-Containing Transcript [NCBI:1269694] [REACTOME:R-HSA-159236]
mRNA 3'-end processing [NCBI:1269692] [REACTOME:R-HSA-72187] [PUBMED:10371034] [PUBMED:10357856] [PUBMED:2408761] [PUBMED:11909521]
mRNA Splicing [NCBI:1269689] [REACTOME:R-HSA-72172] [PUBMED:12226669]
mRNA Splicing - Major Pathway [NCBI:1269690] [REACTOME:R-HSA-72163]
mRNA surveillance pathway [NCBI:193328] [KEGG:hsa03015] [PUBMED:16723977] [PUBMED:18158581] [PUBMED:16715045] [PUBMED:17183357] [PUBMED:15040442]