full name
cullin 4B

synonyms
MRXHF2, MRXS15, MRXSC, SFM2, CUL4B, ENSG00000158290

HGNC
HGNC:2555

Entrez Gene
Gene:8450

ENSEMBL
ENSG00000158290

location
chr: X
start: 119658444
stop: 119709684
strand: -

OMIM
OMIM:300304: CUL4B (X-linked recessive inheritance)
OMIM:300354: Mental retardation, X-linked, syndromic 15 (Cabezas type)

transcripts
NM_003588.3
NM_001079872.1

pathways
DNA Damage Bypass [NCBI:1270367] [REACTOME:R-HSA-73893] [PUBMED:21605556] [PUBMED:10925197] [PUBMED:11595180] [PUBMED:12800216] [PUBMED:19225445] [PUBMED:25038291]
DNA Damage Recognition in GG-NER [NCBI:1309113] [REACTOME:R-HSA-5696394] [PUBMED:15811629] [PUBMED:12944386] [PUBMED:21388382] [PUBMED:14742321] [PUBMED:19609301]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Dual Incision in GG-NER [NCBI:1309115] [REACTOME:R-HSA-5696400] [PUBMED:19279666]
Dual incision in TC-NER [NCBI:1309119] [REACTOME:R-HSA-6782135] [PUBMED:19279666] [PUBMED:23906714] [PUBMED:8078911] [PUBMED:16246722] [PUBMED:19023283] [PUBMED:11904382] [PUBMED:24402227]
Formation of Incision Complex in GG-NER [NCBI:1309114] [REACTOME:R-HSA-5696395] [PUBMED:17948053] [PUBMED:17466626] [PUBMED:11511374] [PUBMED:9716411] [PUBMED:17000769] [PUBMED:15590680] [PUBMED:19940136] [PUBMED:14517266] [PUBMED:16491090] [PUBMED:23038248]
Formation of TC-NER Pre-Incision Complex [NCBI:1309118] [REACTOME:R-HSA-6781823] [PUBMED:12208738] [PUBMED:16916636] [PUBMED:17290000] [PUBMED:25435140] [PUBMED:22466611] [PUBMED:10944529] [PUBMED:22902626] [PUBMED:16751180] [PUBMED:22466610] [PUBMED:8876179] [PUBMED:12660172] [PUBMED:25154395] [PUBMED:8078911]
Gap-filling DNA repair synthesis and ligation in TC-NER [NCBI:1309120] [REACTOME:R-HSA-6782210] [PUBMED:20227374] [PUBMED:19279666] [PUBMED:17643379]
Global Genome Nucleotide Excision Repair (GG-NER) [NCBI:1309112] [REACTOME:R-HSA-5696399] [PUBMED:24954209]
Nucleotide Excision Repair [NCBI:1309111] [REACTOME:R-HSA-5696398] [PUBMED:11900249] [PUBMED:23906714] [PUBMED:14599765] [PUBMED:10583946] [PUBMED:24954209] [PUBMED:19023283]
Nucleotide excision repair [NCBI:83044] [KEGG:hsa03420] [PUBMED:11436323] [PUBMED:18018633] [PUBMED:11436316] [PUBMED:17884153] [PUBMED:11436314] [PUBMED:17276014] [PUBMED:16922398]
Recognition of DNA damage by PCNA-containing replication complex [NCBI:1270368] [REACTOME:R-HSA-110314] [PUBMED:15916957] [PUBMED:12226657]
Transcription-Coupled Nucleotide Excision Repair (TC-NER) [NCBI:1309117] [REACTOME:R-HSA-6781827] [PUBMED:24954209] [PUBMED:11823795] [PUBMED:19023283] [PUBMED:23906714] [PUBMED:3466163]
Ubiquitin mediated proteolysis [NCBI:83056] [KEGG:hsa04120] [PUBMED:16405856] [PUBMED:12944364] [PUBMED:16922408] [PUBMED:17588513] [PUBMED:16922367] [PUBMED:16922370] [PUBMED:16816840]