Home
About
Citations
Statistics
Download
Login
Home
Genes
AGRN
Gene - AGRN
full name
agrin
synonyms
AGRN, ENSG00000188157
HGNC
HGNC:329
Entrez Gene
Gene:375790
ENSEMBL
ENSG00000188157
location
chr: 1
start: 955503
stop: 991499
strand: +
OMIM
OMIM:103320
: AGRN
(Autosomal recessive inheritance)
OMIM:615120
: Myasthenic syndrome, congenital, 8, with pre- and postsynaptic defects
transcripts
NM_198576.3
pathways
A tetrasaccharide linker sequence is required for GAG synthesis
[NCBI:1269981]
[REACTOME:R-HSA-1971475]
[PUBMED:4139221]
[PUBMED:17239764]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Chondroitin sulfate/dermatan sulfate metabolism
[NCBI:1269984]
[REACTOME:R-HSA-1793185]
[PUBMED:12512856]
[PUBMED:12213784]
[PUBMED:17239764]
Defective B3GALT6 causes EDSP2 and SEMDJL1
[NCBI:1309217]
[REACTOME:R-HSA-4420332]
[PUBMED:23664117]
[PUBMED:23664118]
Defective B3GAT3 causes JDSSDHD
[NCBI:1269015]
[REACTOME:R-HSA-3560801]
[PUBMED:1640425]
[PUBMED:14779259]
[PUBMED:21763480]
[PUBMED:4626580]
Defective B4GALT7 causes EDS, progeroid type
[NCBI:1269014]
[REACTOME:R-HSA-3560783]
[PUBMED:10506123]
Defective EXT1 causes exostoses 1, TRPS2 and CHDS
[NCBI:1269021]
[REACTOME:R-HSA-3656253]
[PUBMED:7711731]
[PUBMED:6496574]
[PUBMED:8558565]
[PUBMED:2783565]
[PUBMED:7726168]
[PUBMED:6015756]
Defective EXT2 causes exostoses 2
[NCBI:1269022]
[REACTOME:R-HSA-3656237]
[PUBMED:2783565]
[PUBMED:8558565]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases associated with glycosaminoglycan metabolism
[NCBI:1269011]
[REACTOME:R-HSA-3560782]
[PUBMED:23457301]
Diseases of glycosylation
[NCBI:1269010]
[REACTOME:R-HSA-3781865]
[PUBMED:22983739]
[PUBMED:12756558]
[PUBMED:22343051]
[PUBMED:6543331]
[PUBMED:16755287]
[PUBMED:19765534]
[PUBMED:12409504]
[PUBMED:22838182]
[PUBMED:2301971]
[PUBMED:21384229]
ECM proteoglycans
[NCBI:1270256]
[REACTOME:R-HSA-3000178]
[PUBMED:20301236]
[PUBMED:21307119]
ECM-receptor interaction
[NCBI:83068]
[KEGG:hsa04512]
[PUBMED:7698997]
[PUBMED:15381249]
[PUBMED:12796473]
[PUBMED:11331578]
[PUBMED:15036264]
[PUBMED:12125070]
[PUBMED:12736199]
[PUBMED:15229478]
[PUBMED:11572082]
[PUBMED:10617638]
[PUBMED:12845610]
[PUBMED:12921709]
Extracellular matrix organization
[NCBI:1270244]
[REACTOME:R-HSA-1474244]
[PUBMED:21123617]
[PUBMED:21917992]
[PUBMED:12845610]
Glycosaminoglycan metabolism
[NCBI:1269972]
[REACTOME:R-HSA-1630316]
[PUBMED:18201392]
[PUBMED:20301236]
[PUBMED:820626]
HS-GAG biosynthesis
[NCBI:1269982]
[REACTOME:R-HSA-2022928]
[PUBMED:11102866]
[PUBMED:9251237]
HS-GAG degradation
[NCBI:1269983]
[REACTOME:R-HSA-2024096]
[PUBMED:15647514]
Heparan sulfate/heparin (HS-GAG) metabolism
[NCBI:1269980]
[REACTOME:R-HSA-1638091]
[PUBMED:11102866]
[PUBMED:19111581]
[PUBMED:10716625]
[PUBMED:9251237]
Integrin cell surface interactions
[NCBI:1270260]
[REACTOME:R-HSA-216083]
[PUBMED:10215583]
[PUBMED:15147720]
[PUBMED:12231361]
[PUBMED:8866399]
[PUBMED:19273203]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of carbohydrates
[NCBI:1269957]
[REACTOME:R-HSA-71387]
Metabolism of fat-soluble vitamins
[NCBI:1339147]
[REACTOME:R-HSA-6806667]
[PUBMED:22516726]
[PUBMED:15951480]
[PUBMED:16011460]
Metabolism of vitamins and cofactors
[NCBI:1270144]
[REACTOME:R-HSA-196854]
NCAM signaling for neurite out-growth
[NCBI:1270312]
[REACTOME:R-HSA-375165]
[PUBMED:18760361]
[PUBMED:12587671]
[PUBMED:15662836]
[PUBMED:17975827]
[PUBMED:15153429]
[PUBMED:12700044]
NCAM1 interactions
[NCBI:1270313]
[REACTOME:R-HSA-419037]
[PUBMED:18607724]
[PUBMED:15662836]
Non-integrin membrane-ECM interactions
[NCBI:1270254]
[REACTOME:R-HSA-3000171]
[PUBMED:15039999]
[PUBMED:20565253]
Retinoid metabolism and transport
[NCBI:1269624]
[REACTOME:R-HSA-975634]
[PUBMED:16011460]
[PUBMED:11340090]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Visual phototransduction
[NCBI:1269623]
[REACTOME:R-HSA-2187338]
[PUBMED:15384919]
[PUBMED:22074928]
[PUBMED:20188572]
[PUBMED:21111842]
[PUBMED:16688755]
[PUBMED:8382952]
[PUBMED:22658984]
[PUBMED:20430952]
[PUBMED:21350678]
[PUBMED:22074927]
[PUBMED:16011460]
[PUBMED:11340090]