full name
iduronate 2-sulfatase

synonyms
MPS2, SIDS, IDS, ENSG00000010404

HGNC
HGNC:5389

Entrez Gene
Gene:3423

ENSEMBL
ENSG00000010404
ENSG00000241489
ENSG00000267816
ENSG00000269041

location
chr: X
start: 148560295
stop: 148586884
strand: -

OMIM
OMIM:300823: IDS (X-linked recessive inheritance)
OMIM:309900: Mucopolysaccharidosis II

transcripts
NM_001166550.1
NM_000202.5
NM_006123.4

pathways
CS/DS degradation [NCBI:1269987] [REACTOME:R-HSA-2024101] [PUBMED:15647514]
Chondroitin sulfate/dermatan sulfate metabolism [NCBI:1269984] [REACTOME:R-HSA-1793185] [PUBMED:12512856] [PUBMED:12213784] [PUBMED:17239764]
Dermatan sulfate degradation [NCBI:413375] [KEGG:hsa_M00076]
Glycosaminoglycan degradation [NCBI:82981] [KEGG:hsa00531] [PUBMED:27570] [PUBMED:3161730]
Glycosaminoglycan metabolism [NCBI:1269972] [REACTOME:R-HSA-1630316] [PUBMED:18201392] [PUBMED:20301236] [PUBMED:820626]
HS-GAG degradation [NCBI:1269983] [REACTOME:R-HSA-2024096] [PUBMED:15647514]
Heparan sulfate degradation [NCBI:413377] [KEGG:hsa_M00078]
Heparan sulfate/heparin (HS-GAG) metabolism [NCBI:1269980] [REACTOME:R-HSA-1638091] [PUBMED:11102866] [PUBMED:19111581] [PUBMED:10716625] [PUBMED:9251237]
Lysosome [NCBI:99052] [KEGG:hsa04142] [PUBMED:2943218] [PUBMED:12628346] [PUBMED:1883197] [PUBMED:18635948] [PUBMED:15987739]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]