full name
inhibitor of nuclear factor kappa B kinase subunit gamma
synonyms
AMCBX1, FIP-3, FIP3, Fip3p, IKK-gamma, IP, IP1, IP2, IPD2, NEMO, ZC2HC9, IKBKG, ENSG00000269335
HGNC
HGNC:5961
Entrez Gene
Gene:8517
ENSEMBL
ENSG00000269335
ENSG00000073009
location
chr: X
start: 153769419
stop: 153796804
strand: +
OMIM
OMIM:300248:
IKBKG
(X-linked recessive inheritance)
OMIM:300291:
Ectodermal dysplasia and immunodeficiency 1
OMIM:300636:
Immunodeficiency 33
OMIM:308300:
Incontinentia pigmenti
transcripts
NM_001099856.2
NM_001099857.1
NM_001145255.1
NM_003639.3
pathways
Activated TLR4 signalling
[NCBI:1269236]
[REACTOME:R-HSA-166054]
[PUBMED:15276183]
[PUBMED:15588429]
[PUBMED:15845500]
[PUBMED:15596121]
Activation of NF-kappaB in B cells
[NCBI:1269186]
[REACTOME:R-HSA-1169091]
[PUBMED:10593898]
[PUBMED:3129195]
[PUBMED:7479848]
[PUBMED:7809113]
[PUBMED:9721103]
[PUBMED:18462924]
[PUBMED:8387275]
[PUBMED:7628694]
[PUBMED:7862124]
[PUBMED:7831327]
[PUBMED:7575604]
[PUBMED:16356855]
[PUBMED:16301747]
[PUBMED:7957109]
[PUBMED:11460167]
[PUBMED:9914500]
[PUBMED:19066035]
[PUBMED:17428801]
[PUBMED:7479976]
[PUBMED:1756723]
Acute myeloid leukemia
[NCBI:83117]
[KEGG:hsa05221]
[PUBMED:12951584]
[PUBMED:12563308]
[PUBMED:16352814]
[PUBMED:16236521]
[PUBMED:16146838]
[PUBMED:16642045]
[PUBMED:15625120]
[PUBMED:11721960]
[PUBMED:17554387]
[PUBMED:12468433]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Adipocytokine signaling pathway
[NCBI:83093]
[KEGG:hsa04920]
[PUBMED:12829246]
[PUBMED:10905472]
[PUBMED:15980064]
[PUBMED:12754525]
[PUBMED:12368907]
[PUBMED:11557972]
[PUBMED:15856064]
[PUBMED:9671776]
[PUBMED:10766253]
[PUBMED:15733744]
[PUBMED:15058305]
[PUBMED:14716305]
[PUBMED:11479627]
[PUBMED:14679176]
Antifolate resistance
[NCBI:1440526]
[KEGG:hsa01523]
[PUBMED:17333344]
[PUBMED:23987246]
[PUBMED:11509639]
[PUBMED:24732946]
[PUBMED:8793930]
[PUBMED:15117425]
[PUBMED:22921318]
[PUBMED:16491071]
[PUBMED:26920997]
[PUBMED:22954694]
[PUBMED:17092765]
[PUBMED:17203006]
[PUBMED:23897011]
[PUBMED:21317831]
[PUBMED:18297517]
[PUBMED:14576850]
[PUBMED:16380836]
Antigen processing-Cross presentation
[NCBI:1269195]
[REACTOME:R-HSA-1236975]
[PUBMED:17157489]
[PUBMED:20171863]
[PUBMED:16181333]
[PUBMED:15761154]
[PUBMED:16181335]
[PUBMED:19218463]
Apoptosis
[NCBI:83060]
[KEGG:hsa04210]
[NCBI:1270262]
[REACTOME:R-HSA-109581]
[PUBMED:12189384]
[PUBMED:20533903]
[PUBMED:18208375]
[PUBMED:22429822]
[PUBMED:15218528]
[PUBMED:24769728]
[PUBMED:18023214]
[PUBMED:25526085]
[PUBMED:23070002]
[PUBMED:15654015]
[PUBMED:15601572]
[PUBMED:14561771]
[PUBMED:24278747]
[PUBMED:21914490]
[PUBMED:22465226]
[PUBMED:21145844]
[PUBMED:12838338]
[PUBMED:18238895]
[PUBMED:12949498]
[PUBMED:18304445]
[PUBMED:14737178]
[PUBMED:26231733]
[PUBMED:9916983]
[PUBMED:14634621]
[PUBMED:19770840]
[PUBMED:22075987]
[PUBMED:4561027]
[PUBMED:20075940]
[PUBMED:9894605]
[PUBMED:26615431]
[PUBMED:12505355]
[PUBMED:11520933]
[PUBMED:19148180]
[PUBMED:16397578]
[PUBMED:15719025]
[PUBMED:15322527]
[PUBMED:15725726]
[PUBMED:12209154]
[PUBMED:23803157]
B cell receptor signaling pathway
[NCBI:83081]
[KEGG:hsa04662]
[PUBMED:15626471]
[PUBMED:12119152]
[PUBMED:15886119]
[PUBMED:12461567]
[PUBMED:9697839]
[PUBMED:15752555]
[PUBMED:11163197]
[PUBMED:18086859]
[PUBMED:15364057]
[PUBMED:15457440]
[PUBMED:15322145]
[PUBMED:15771577]
[PUBMED:12033741]
[PUBMED:15886112]
[PUBMED:10358768]
BCR signaling pathway
[NCBI:138058]
[Pathway Interaction Database:bcr_5pathway]
[PUBMED:7687428]
[PUBMED:16200195]
[PUBMED:12730099]
[PUBMED:10770799]
[PUBMED:14563325]
[PUBMED:9763608]
[PUBMED:15541657]
[PUBMED:11781242]
[PUBMED:11102801]
[PUBMED:9586640]
[PUBMED:11279148]
[PUBMED:7499277]
[PUBMED:7542197]
[PUBMED:9820480]
[PUBMED:9221755]
[PUBMED:11909947]
[PUBMED:9360945]
[PUBMED:9058799]
[PUBMED:10339589]
[PUBMED:11226282]
[PUBMED:9271416]
[PUBMED:9620684]
[PUBMED:11163197]
[PUBMED:10820378]
[PUBMED:11356195]
[PUBMED:11080163]
[PUBMED:10755621]
[PUBMED:7717978]
[PUBMED:7618087]
[PUBMED:11577348]
[PUBMED:1279802]
[PUBMED:10640270]
[PUBMED:11356834]
[PUBMED:12867038]
[PUBMED:12780340]
[PUBMED:10430908]
[PUBMED:7528218]
C-type lectin receptors (CLRs)
[NCBI:1269303]
[REACTOME:R-HSA-5621481]
[PUBMED:19521399]
[PUBMED:24330199]
CLEC7A (Dectin-1) signaling
[NCBI:1269304]
[REACTOME:R-HSA-5607764]
[PUBMED:12719478]
[PUBMED:19223162]
Canonical NF-kappaB pathway
[NCBI:138030]
[Pathway Interaction Database:nfkappabcanonicalpathway]
[PUBMED:7878466]
[PUBMED:10688673]
[PUBMED:16497931]
[PUBMED:10755617]
[PUBMED:9660950]
[PUBMED:9346241]
[PUBMED:10195894]
[PUBMED:10521409]
[PUBMED:12917691]
[PUBMED:15620648]
[PUBMED:14695475]
[PUBMED:14651848]
[PUBMED:11319224]
[PUBMED:9150141]
[PUBMED:9819420]
[PUBMED:15218148]
[PUBMED:7739562]
[PUBMED:12657630]
[PUBMED:12867425]
[PUBMED:16267042]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Chemokine signaling pathway
[NCBI:99051]
[KEGG:hsa04062]
[PUBMED:17371236]
[PUBMED:19159344]
[PUBMED:17169327]
[PUBMED:10852130]
[PUBMED:9765254]
[PUBMED:15771581]
[PUBMED:14607270]
[PUBMED:18662984]
[PUBMED:12495636]
[PUBMED:15803148]
[PUBMED:15046611]
[PUBMED:12069927]
[PUBMED:18711432]
[PUBMED:17675482]
[PUBMED:16144840]
[PUBMED:17496928]
[PUBMED:17537990]
[PUBMED:11872087]
[PUBMED:12051620]
[PUBMED:14625285]
[PUBMED:8576262]
[PUBMED:11244042]
Chronic myeloid leukemia
[NCBI:83116]
[KEGG:hsa05220]
[PUBMED:22286129]
[PUBMED:12801837]
[PUBMED:11160144]
[PUBMED:15719031]
[PUBMED:10403855]
[PUBMED:9834202]
[PUBMED:11071626]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16484590]
[PUBMED:14982876]
Class I MHC mediated antigen processing & presentation
[NCBI:1269192]
[REACTOME:R-HSA-983169]
[PUBMED:8717519]
[PUBMED:17145306]
[PUBMED:18926908]
[PUBMED:17055423]
[PUBMED:12495737]
[PUBMED:18641646]
[PUBMED:18243674]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Cytosolic DNA-sensing pathway
[NCBI:125137]
[KEGG:hsa04623]
[PUBMED:18573338]
[PUBMED:19665965]
[PUBMED:19567913]
[PUBMED:18280611]
[PUBMED:18724932]
[PUBMED:19497760]
[PUBMED:16286919]
[PUBMED:19122387]
[PUBMED:19590578]
[PUBMED:23258413]
[PUBMED:18375758]
[PUBMED:19321146]
[PUBMED:19362700]
[PUBMED:18941233]
[PUBMED:19767723]
Cytosolic sensors of pathogen-associated DNA
[NCBI:1269268]
[REACTOME:R-HSA-1834949]
[PUBMED:23706668]
[PUBMED:21533068]
[PUBMED:23706667]
Death Receptor Signalling
[NCBI:1269644]
[REACTOME:R-HSA-73887]
Deubiquitination
[NCBI:1427860]
[REACTOME:R-HSA-5688426]
[PUBMED:19243136]
[PUBMED:20074029]
[PUBMED:15571815]
[PUBMED:20418328]
[PUBMED:16325574]
[PUBMED:12944365]
[PUBMED:23845989]
[PUBMED:22201797]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases associated with the TLR signaling cascade
[NCBI:1269157]
[REACTOME:R-HSA-5602358]
[PUBMED:23622315]
[PUBMED:21734245]
[PUBMED:22610250]
[PUBMED:16176658]
Diseases of Immune System
[NCBI:1269156]
[REACTOME:R-HSA-5260271]
[PUBMED:24795713]
[PUBMED:22165913]
Downstream TCR signaling
[NCBI:1269176]
[REACTOME:R-HSA-202424]
[PUBMED:15084594]
Downstream signaling events of B Cell Receptor (BCR)
[NCBI:1269185]
[REACTOME:R-HSA-1168372]
[PUBMED:17052215]
[PUBMED:19909372]
ER-Phagosome pathway
[NCBI:1269197]
[REACTOME:R-HSA-1236974]
[PUBMED:16213220]
[PUBMED:20171863]
[PUBMED:14508490]
[PUBMED:17027300]
[PUBMED:14561893]
[PUBMED:15845646]
[PUBMED:22915823]
[PUBMED:18006660]
[PUBMED:14508489]
[PUBMED:12151002]
[PUBMED:15728715]
Epithelial cell signaling in Helicobacter pylori infection
[NCBI:83102]
[KEGG:hsa05120]
[PUBMED:11389469]
[PUBMED:15694859]
[PUBMED:14700549]
[PUBMED:12197905]
Epstein-Barr virus infection
[NCBI:585562]
[KEGG:hsa05169]
[PUBMED:1658397]
[PUBMED:10683340]
[PUBMED:19375142]
[PUBMED:12438576]
[PUBMED:12910248]
[PUBMED:10400785]
[PUBMED:16007144]
[PUBMED:14576817]
[PUBMED:18559925]
[PUBMED:16352731]
[PUBMED:7895172]
[PUBMED:15510157]
[PUBMED:21518914]
[PUBMED:10891508]
[PUBMED:14673102]
[PUBMED:17159145]
[PUBMED:15542638]
[PUBMED:18786993]
[PUBMED:16603506]
[PUBMED:10644367]
[PUBMED:15021898]
[PUBMED:10666279]
[PUBMED:9565632]
FAS (CD95) signaling pathway
[NCBI:138081]
[Pathway Interaction Database:faspathway]
[PUBMED:9765224]
[PUBMED:11717445]
[PUBMED:9727491]
[PUBMED:11279218]
[PUBMED:12110583]
[PUBMED:11739735]
[PUBMED:8521815]
[PUBMED:9184224]
[PUBMED:20153221]
[PUBMED:9126929]
[PUBMED:10200443]
[PUBMED:16033886]
[PUBMED:8681377]
[PUBMED:9880544]
[PUBMED:9501089]
[PUBMED:10535980]
[PUBMED:9727492]
[PUBMED:7523573]
[PUBMED:11101870]
[PUBMED:9321399]
[PUBMED:9362518]
[PUBMED:12724420]
[PUBMED:16498403]
[PUBMED:11583996]
[PUBMED:15557123]
[PUBMED:7536343]
[PUBMED:12832037]
[PUBMED:9576928]
[PUBMED:9228058]
[PUBMED:7538908]
[PUBMED:18635548]
[PUBMED:20038679]
[PUBMED:10894163]
[PUBMED:12545171]
[PUBMED:16619028]
[PUBMED:9351817]
[PUBMED:9045686]
[PUBMED:15289496]
FCERI mediated NF-kB activation
[NCBI:1269301]
[REACTOME:R-HSA-2871837]
[PUBMED:17336609]
[PUBMED:16432253]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Fc-epsilon receptor I signaling in mast cells
[NCBI:138050]
[Pathway Interaction Database:fcer1pathway]
[PUBMED:9556577]
[PUBMED:8629002]
[PUBMED:12217401]
[PUBMED:15010370]
[PUBMED:15608142]
[PUBMED:7561053]
[PUBMED:7537741]
[PUBMED:7963537]
[PUBMED:8947047]
[PUBMED:1384468]
[PUBMED:14757742]
[PUBMED:16174756]
[PUBMED:10583594]
[PUBMED:7513150]
[PUBMED:12089510]
[PUBMED:10811803]
[PUBMED:9268346]
[PUBMED:12640123]
[PUBMED:9108083]
[PUBMED:8602265]
[PUBMED:11340169]
[PUBMED:12953098]
[PUBMED:11465115]
[PUBMED:7730640]
[PUBMED:9550384]
[PUBMED:7518558]
[PUBMED:11137136]
[PUBMED:15282299]
[PUBMED:14634134]
[PUBMED:8534912]
[PUBMED:16002993]
[PUBMED:12192036]
[PUBMED:7608202]
[PUBMED:11714805]
[PUBMED:11970986]
[PUBMED:10903718]
[PUBMED:15265912]
[PUBMED:15477350]
Fluid shear stress and atherosclerosis
[NCBI:1474302]
[KEGG:hsa05418]
[PUBMED:23429585]
[PUBMED:21050140]
[PUBMED:17599600]
[PUBMED:24190880]
[PUBMED:22003002]
[PUBMED:24876354]
[PUBMED:24947523]
[PUBMED:23899566]
[PUBMED:26597822]
[PUBMED:20353494]
[PUBMED:22076424]
[PUBMED:20538799]
[PUBMED:25165867]
[PUBMED:20032497]
[PUBMED:23084990]
[PUBMED:26822720]
[PUBMED:24573382]
[PUBMED:23555159]
[PUBMED:26212910]
[PUBMED:21457103]
[PUBMED:19151844]
[PUBMED:15388638]
[PUBMED:16765337]
[PUBMED:27027326]
[PUBMED:25638487]
[PUBMED:21733876]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
Hepatitis C
[NCBI:173973]
[KEGG:hsa05160]
[PUBMED:19708811]
[PUBMED:16314558]
[PUBMED:17467654]
[PUBMED:19515018]
[PUBMED:18514579]
[PUBMED:16107833]
[PUBMED:19074178]
[PUBMED:12691459]
[PUBMED:15302943]
[PUBMED:20537953]
[PUBMED:11991644]
[PUBMED:19148799]
[PUBMED:19187070]
[PUBMED:12655344]
Herpes simplex infection
[NCBI:377873]
[KEGG:hsa05168]
[PUBMED:12224518]
[PUBMED:17913820]
[PUBMED:12844494]
[PUBMED:10998601]
[PUBMED:15163721]
[PUBMED:19694546]
[PUBMED:16297150]
[PUBMED:14747533]
[PUBMED:12826401]
[PUBMED:14963113]
[PUBMED:15056211]
[PUBMED:12797447]
[PUBMED:21107701]
[PUBMED:10918307]
[PUBMED:10696424]
[PUBMED:16076403]
[PUBMED:10364308]
[PUBMED:17222692]
[PUBMED:9621021]
[PUBMED:12224508]
[PUBMED:19879619]
[PUBMED:11070032]
[PUBMED:9499021]
[PUBMED:18596690]
[PUBMED:12525427]
[PUBMED:12224517]
[PUBMED:10196275]
[PUBMED:15047834]
[PUBMED:18508584]
[PUBMED:20036979]
IKBKB deficiency causes SCID
[NCBI:1269167]
[REACTOME:R-HSA-5602636]
[PUBMED:24369075]
IKBKG deficiency causes anhidrotic ectodermal dysplasia with immunodeficiency (EDA-ID) (via TLR)
[NCBI:1269166]
[REACTOME:R-HSA-5603027]
[PUBMED:18851874]
[PUBMED:15229184]
[PUBMED:11242109]
IKK complex recruitment mediated by RIP1
[NCBI:1269223]
[REACTOME:R-HSA-937041]
[PUBMED:16603398]
[PUBMED:16115877]
[PUBMED:14530355]
IL-17 signaling pathway
[NCBI:1474301]
[KEGG:hsa04657]
[PUBMED:17921324]
[PUBMED:24011563]
[PUBMED:21349428]
[PUBMED:20383173]
[PUBMED:20514051]
[PUBMED:20177959]
[PUBMED:18178098]
[PUBMED:21074482]
[PUBMED:21130872]
[PUBMED:17027518]
[PUBMED:23917206]
[PUBMED:23116200]
[PUBMED:18701318]
[PUBMED:26252407]
[PUBMED:22851696]
[PUBMED:21155836]
[PUBMED:25145755]
[PUBMED:17177681]
[PUBMED:19575028]
[PUBMED:23557798]
[PUBMED:21852080]
[PUBMED:22324470]
IL1-mediated signaling events
[NCBI:137944]
[Pathway Interaction Database:il1pathway]
[PUBMED:10854325]
[PUBMED:11287640]
[PUBMED:10747026]
[PUBMED:11960013]
[PUBMED:12150927]
[PUBMED:1837145]
[PUBMED:17197697]
[PUBMED:9374458]
[PUBMED:12721283]
[PUBMED:8035875]
[PUBMED:9261174]
[PUBMED:9734363]
[PUBMED:11460167]
[PUBMED:7878046]
[PUBMED:10373529]
[PUBMED:2530587]
[PUBMED:12538665]
[PUBMED:10882101]
[PUBMED:9360994]
[PUBMED:9062194]
[PUBMED:12242293]
[PUBMED:8837778]
[PUBMED:9430229]
[PUBMED:7775431]
IRAK1 recruits IKK complex
[NCBI:1269208]
[REACTOME:R-HSA-937039]
[PUBMED:14625308]
[PUBMED:12856330]
[PUBMED:16477006]
[PUBMED:15767370]
[PUBMED:18347055]
[PUBMED:15695821]
[PUBMED:14661019]
[PUBMED:18276832]
IRAK1 recruits IKK complex upon TLR7/8 or 9 stimulation
[NCBI:1269230]
[REACTOME:R-HSA-975144]
[PUBMED:16477006]
[PUBMED:15767370]
[PUBMED:18347055]
[PUBMED:15695821]
[PUBMED:14661019]
[PUBMED:18276832]
[PUBMED:14625308]
[PUBMED:12856330]
IkBA variant leads to EDA-ID
[NCBI:1269168]
[REACTOME:R-HSA-5603029]
[PUBMED:18412279]
[PUBMED:23708964]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Interleukin-1 signaling
[NCBI:1269320]
[REACTOME:R-HSA-446652]
[PUBMED:19302047]
[PUBMED:19022706]
JNK (c-Jun kinases) phosphorylation and activation mediated by activated human TAK1
[NCBI:1269212]
[REACTOME:R-HSA-450321]
[PUBMED:15837794]
[PUBMED:11460167]
MAP kinase activation in TLR cascade
[NCBI:1269211]
[REACTOME:R-HSA-450294]
[PUBMED:17637696]
[PUBMED:11861597]
[PUBMED:19196711]
[PUBMED:11242034]
MAP3K8 (TPL2)-dependent MAPK1/3 activation
[NCBI:1309122]
[REACTOME:R-HSA-5684264]
[PUBMED:22733995]
[PUBMED:21135874]
MAPK signaling pathway
[NCBI:83048]
[KEGG:hsa04010]
[PUBMED:11749383]
[PUBMED:12566928]
[PUBMED:12849693]
[PUBMED:12676795]
[PUBMED:12947395]
[PUBMED:14597384]
[PUBMED:11369511]
[PUBMED:12191611]
[PUBMED:12390245]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
MyD88 cascade initiated on plasma membrane
[NCBI:1269207]
[REACTOME:R-HSA-975871]
[PUBMED:15728506]
[PUBMED:16239509]
MyD88 dependent cascade initiated on endosome
[NCBI:1269228]
[REACTOME:R-HSA-975155]
[PUBMED:20237413]
[PUBMED:15276183]
[PUBMED:18652679]
MyD88-independent TLR3/TLR4 cascade
[NCBI:1269220]
[REACTOME:R-HSA-166166]
[PUBMED:15276183]
MyD88:Mal cascade initiated on plasma membrane
[NCBI:1269237]
[REACTOME:R-HSA-166058]
[PUBMED:15276183]
NF-kB activation through FADD/RIP-1 pathway mediated by caspase-8 and -10
[NCBI:1269261]
[REACTOME:R-HSA-933543]
[PUBMED:16618810]
[PUBMED:16127453]
[PUBMED:16585540]
[PUBMED:12884866]
NF-kappa B signaling pathway
[NCBI:634527]
[KEGG:hsa04064]
[PUBMED:22119011]
[PUBMED:16264088]
[PUBMED:21187855]
[PUBMED:15546385]
[PUBMED:17607554]
[PUBMED:21135871]
[PUBMED:16984817]
[PUBMED:17047224]
[PUBMED:19203223]
[PUBMED:20300215]
[PUBMED:14657271]
[PUBMED:17431096]
[PUBMED:15134788]
[PUBMED:16356770]
[PUBMED:21772278]
[PUBMED:12654254]
[PUBMED:22390971]
[PUBMED:22017435]
[PUBMED:17183360]
[PUBMED:21173796]
[PUBMED:15905862]
[PUBMED:19302050]
[PUBMED:17098202]
[PUBMED:21872579]
[PUBMED:22152226]
[PUBMED:18613837]
[PUBMED:19489733]
[PUBMED:11875461]
[PUBMED:19726767]
[PUBMED:22017430]
[PUBMED:21232019]
[PUBMED:18832076]
NOD-like receptor signaling pathway
[NCBI:122191]
[KEGG:hsa04621]
[PUBMED:25330206]
[PUBMED:21575908]
[PUBMED:23846113]
[PUBMED:26549800]
[PUBMED:16493424]
[PUBMED:23124073]
[PUBMED:24840700]
[PUBMED:27291964]
[PUBMED:27012466]
[PUBMED:24707857]
[PUBMED:19767725]
[PUBMED:25879280]
[PUBMED:23215645]
[PUBMED:22819539]
[PUBMED:23702978]
[PUBMED:20643110]
[PUBMED:25879288]
[PUBMED:26655628]
[PUBMED:25145756]
[PUBMED:24718315]
[PUBMED:26482951]
[PUBMED:25526305]
[PUBMED:26121197]
[PUBMED:22430786]
NOD1/2 Signaling Pathway
[NCBI:1269252]
[REACTOME:R-HSA-168638]
[PUBMED:18928408]
[PUBMED:18585455]
[PUBMED:18414735]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
[NCBI:1269251]
[REACTOME:R-HSA-168643]
[PUBMED:18928408]
Osteoclast differentiation
[NCBI:193147]
[KEGG:hsa04380]
[PUBMED:17633024]
[PUBMED:18382763]
[PUBMED:18329366]
[PUBMED:17869613]
[PUBMED:18722561]
[PUBMED:15122243]
[PUBMED:20703218]
[PUBMED:12748652]
[PUBMED:12110142]
[PUBMED:19585227]
[PUBMED:15546140]
[PUBMED:16184196]
[PUBMED:15817678]
[PUBMED:20392226]
[PUBMED:16313349]
[PUBMED:16313342]
[PUBMED:17380158]
[PUBMED:18451259]
Ovarian tumor domain proteases
[NCBI:1427863]
[REACTOME:R-HSA-5689896]
[PUBMED:23827681]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Pancreatic cancer
[NCBI:83108]
[KEGG:hsa05212]
[PUBMED:12079267]
[PUBMED:14967450]
[PUBMED:15774796]
[PUBMED:10740269]
[PUBMED:12946833]
[PUBMED:16702400]
[PUBMED:14586404]
[PUBMED:15823750]
[PUBMED:12648469]
[PUBMED:11407945]
[PUBMED:12459728]
[PUBMED:14580692]
[PUBMED:11707511]
[PUBMED:12545153]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Post-translational protein modification
[NCBI:1268701]
[REACTOME:R-HSA-597592]
Primary immunodeficiency
[NCBI:83125]
[KEGG:hsa05340]
[PUBMED:11941303]
[PUBMED:18093537]
[PUBMED:11058677]
[PUBMED:17952897]
[PUBMED:14699405]
[PUBMED:15661024]
[PUBMED:14647478]
[PUBMED:17960151]
[PUBMED:16261175]
Prostate cancer
[NCBI:83111]
[KEGG:hsa05215]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11527574]
[PUBMED:11750244]
[PUBMED:16551847]
[PUBMED:10835690]
[PUBMED:8069858]
[PUBMED:15724144]
[PUBMED:10453277]
[PUBMED:15082523]
[PUBMED:9422516]
RIG-I-like receptor signaling pathway
[NCBI:117292]
[KEGG:hsa04622]
[PUBMED:19224920]
[PUBMED:19076341]
[PUBMED:18549796]
[PUBMED:18591413]
[PUBMED:19615405]
[PUBMED:19120475]
[PUBMED:18439848]
[PUBMED:19120476]
[PUBMED:15208624]
[PUBMED:19539500]
[PUBMED:18272355]
[PUBMED:18984593]
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways
[NCBI:1269259]
[REACTOME:R-HSA-168928]
[PUBMED:17395582]
[PUBMED:17942531]
[PUBMED:18701081]
[PUBMED:17683970]
[PUBMED:18989317]
[PUBMED:16214811]
RIP-mediated NFkB activation via ZBP1
[NCBI:1269271]
[REACTOME:R-HSA-1810476]
[PUBMED:18941233]
[PUBMED:19590578]
Ras signaling pathway
[NCBI:868085]
[KEGG:hsa04014]
[PUBMED:23506953]
[PUBMED:18437264]
[PUBMED:15062121]
[PUBMED:22189424]
[PUBMED:22233291]
[PUBMED:12778136]
[PUBMED:11313946]
[PUBMED:17428555]
[PUBMED:19091743]
[PUBMED:18568040]
[PUBMED:20420946]
[PUBMED:12217381]
[PUBMED:14663478]
[PUBMED:21686117]
[PUBMED:12642680]
[PUBMED:21196257]
[PUBMED:16869784]
[PUBMED:21111786]
[PUBMED:16966426]
[PUBMED:10712923]
[PUBMED:22020205]
[PUBMED:17384584]
[PUBMED:15572660]
[PUBMED:18413813]
Regulation of TNFR1 signaling
[NCBI:1309094]
[REACTOME:R-HSA-5357905]
[PUBMED:22435550]
[PUBMED:11432772]
[PUBMED:12724336]
Shigellosis
[NCBI:83104]
[KEGG:hsa05131]
[PUBMED:11379633]
[PUBMED:10491394]
[PUBMED:17173036]
[PUBMED:18202440]
[PUBMED:17095701]
[PUBMED:16622194]
[PUBMED:16413487]
[PUBMED:18005683]
[PUBMED:15731041]
[PUBMED:15073367]
[PUBMED:12856283]
[PUBMED:16939534]
[PUBMED:17060328]
[PUBMED:12065406]
[PUBMED:8376337]
[PUBMED:11207560]
[PUBMED:8642302]
[PUBMED:12356723]
[PUBMED:15694852]
[PUBMED:10369666]
[PUBMED:14638419]
[PUBMED:16441429]
[PUBMED:16162672]
[PUBMED:17719540]
[PUBMED:7665485]
[PUBMED:18059288]
[PUBMED:18005697]
[PUBMED:19165331]
[PUBMED:12828640]
[PUBMED:17662586]
[PUBMED:9176079]
[PUBMED:7591128]
[PUBMED:15318166]
[PUBMED:15950937]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by the B Cell Receptor (BCR)
[NCBI:1269183]
[REACTOME:R-HSA-983705]
[PUBMED:1702903]
[PUBMED:2011584]
[PUBMED:1081164]
[PUBMED:19065780]
[PUBMED:16849466]
[PUBMED:1375264]
[PUBMED:7538118]
[PUBMED:11901194]
[PUBMED:8580068]
[PUBMED:19249086]
[PUBMED:18596693]
[PUBMED:10648173]
[PUBMED:4589993]
[PUBMED:8163536]
[PUBMED:1376928]
[PUBMED:7688784]
[PUBMED:6335036]
[PUBMED:17052215]
[PUBMED:18818202]
[PUBMED:20206686]
[PUBMED:7592958]
[PUBMED:7524079]
[PUBMED:15489917]
[PUBMED:15509800]
[PUBMED:18187424]
[PUBMED:7927516]
[PUBMED:803528]
[PUBMED:19909372]
[PUBMED:20192804]
[PUBMED:8306975]
Small cell lung cancer
[NCBI:83118]
[KEGG:hsa05222]
[PUBMED:12711111]
[PUBMED:11463388]
[PUBMED:12741677]
[PUBMED:11905738]
[PUBMED:11807782]
[PUBMED:12379883]
[PUBMED:12243753]
[PUBMED:12616528]
[PUBMED:11720739]
[PUBMED:15109562]
[PUBMED:12407699]
[PUBMED:10944551]
[PUBMED:16112428]
[PUBMED:11559746]
[PUBMED:16064138]
[PUBMED:11902573]
T cell receptor signaling pathway
[NCBI:83080]
[KEGG:hsa04660]
[PUBMED:17395537]
[PUBMED:15308211]
[PUBMED:15928679]
[PUBMED:14656980]
[PUBMED:17187070]
[PUBMED:15084594]
[PUBMED:16799472]
[PUBMED:12669022]
[PUBMED:15286727]
[PUBMED:15122199]
[PUBMED:19132916]
[PUBMED:15489916]
[PUBMED:11905831]
[PUBMED:12195013]
[PUBMED:15343367]
[PUBMED:12133805]
[PUBMED:14647476]
[PUBMED:15771581]
[PUBMED:15099566]
[PUBMED:14617194]
[PUBMED:19290929]
[PUBMED:15345216]
TAK1 activates NFkB by phosphorylation and activation of IKKs complex
[NCBI:1269210]
[REACTOME:R-HSA-445989]
[PUBMED:15837794]
[PUBMED:11460167]
TCR signaling
[NCBI:1269172]
[REACTOME:R-HSA-202403]
[PUBMED:10375551]
[PUBMED:12876557]
[PUBMED:9989491]
TCR signaling in naive CD4+ T cells
[NCBI:137998]
[Pathway Interaction Database:tcr_pathway]
[PUBMED:11376344]
[PUBMED:9094314]
[PUBMED:8083187]
[PUBMED:11994416]
[PUBMED:16365455]
[PUBMED:10072079]
[PUBMED:12361955]
[PUBMED:12755691]
[PUBMED:8642247]
[PUBMED:15125833]
[PUBMED:7509360]
[PUBMED:11353765]
[PUBMED:12941616]
[PUBMED:8700169]
[PUBMED:11120819]
[PUBMED:15899849]
[PUBMED:8990121]
[PUBMED:8702662]
[PUBMED:8164687]
[PUBMED:2141684]
[PUBMED:11567141]
[PUBMED:9846481]
[PUBMED:9489702]
[PUBMED:10811803]
[PUBMED:11368773]
[PUBMED:14557276]
[PUBMED:2548204]
[PUBMED:10318843]
[PUBMED:15536066]
[PUBMED:10652356]
[PUBMED:7568038]
[PUBMED:11175263]
[PUBMED:9438848]
[PUBMED:9692882]
[PUBMED:10209031]
[PUBMED:7509083]
[PUBMED:12874226]
[PUBMED:8673706]
[PUBMED:16733527]
[PUBMED:9822663]
[PUBMED:12738795]
[PUBMED:11904433]
[PUBMED:8084588]
[PUBMED:8114715]
[PUBMED:9312162]
[PUBMED:8790380]
[PUBMED:9677202]
[PUBMED:15802604]
[PUBMED:14702343]
[PUBMED:10903746]
[PUBMED:10807788]
[PUBMED:8176201]
[PUBMED:9207119]
[PUBMED:10790433]
[PUBMED:8892604]
[PUBMED:9665884]
[PUBMED:1639064]
[PUBMED:12421919]
[PUBMED:8246987]
[PUBMED:9710204]
[PUBMED:8146197]
[PUBMED:2190221]
[PUBMED:10229072]
[PUBMED:10021361]
[PUBMED:9924026]
[PUBMED:12186560]
[PUBMED:16649996]
[PUBMED:11287959]
[PUBMED:12917261]
[PUBMED:7545666]
[PUBMED:11250890]
[PUBMED:12842872]
[PUBMED:15879121]
[PUBMED:11567140]
[PUBMED:10209041]
[PUBMED:10556826]
[PUBMED:8183372]
[PUBMED:12397360]
[PUBMED:10506192]
[PUBMED:10861059]
[PUBMED:12507424]
[PUBMED:12845325]
[PUBMED:10745081]
[PUBMED:8195151]
[PUBMED:12024036]
[PUBMED:7524075]
[PUBMED:1464315]
[PUBMED:12138205]
[PUBMED:7544353]
[PUBMED:16906149]
[PUBMED:9637919]
[PUBMED:2470098]
[PUBMED:3919143]
[PUBMED:16005298]
[PUBMED:10918068]
[PUBMED:8636141]
[PUBMED:16921383]
[PUBMED:8479536]
[PUBMED:7556092]
[PUBMED:16582901]
[PUBMED:8805223]
[PUBMED:15933714]
[PUBMED:10224278]
[PUBMED:9819387]
[PUBMED:12881521]
[PUBMED:14988727]
[PUBMED:16849481]
[PUBMED:11390650]
TCR signaling in naive CD8+ T cells
[NCBI:138055]
[Pathway Interaction Database:cd8tcrpathway]
[PUBMED:9094314]
[PUBMED:15125833]
[PUBMED:11994416]
[PUBMED:7509360]
[PUBMED:12755691]
[PUBMED:8642247]
[PUBMED:12361955]
[PUBMED:11956228]
[PUBMED:10072079]
[PUBMED:8977171]
[PUBMED:2141684]
[PUBMED:8700169]
[PUBMED:8164687]
[PUBMED:9489702]
[PUBMED:8702662]
[PUBMED:2548204]
[PUBMED:11175263]
[PUBMED:8114715]
[PUBMED:10209031]
[PUBMED:15536066]
[PUBMED:7678351]
[PUBMED:8673703]
[PUBMED:7830771]
[PUBMED:7509083]
[PUBMED:16733527]
[PUBMED:9438848]
[PUBMED:8790380]
[PUBMED:1639064]
[PUBMED:15980863]
[PUBMED:8084588]
[PUBMED:14702343]
[PUBMED:10790433]
[PUBMED:10807788]
[PUBMED:16169499]
[PUBMED:15802604]
[PUBMED:8892604]
[PUBMED:2114552]
[PUBMED:12421919]
[PUBMED:12917261]
[PUBMED:8146197]
[PUBMED:1335364]
[PUBMED:10021361]
[PUBMED:8183372]
[PUBMED:8627172]
[PUBMED:8898939]
[PUBMED:2190221]
[PUBMED:9710204]
[PUBMED:11287959]
[PUBMED:14764585]
[PUBMED:12954628]
[PUBMED:10209041]
[PUBMED:1464315]
[PUBMED:12507424]
[PUBMED:12732656]
[PUBMED:8195151]
[PUBMED:12138205]
[PUBMED:16005298]
[PUBMED:9312149]
[PUBMED:7544353]
[PUBMED:16906149]
[PUBMED:9637919]
[PUBMED:12845325]
[PUBMED:2470098]
[PUBMED:10918068]
[PUBMED:16116204]
[PUBMED:16921383]
[PUBMED:10562325]
[PUBMED:9819387]
[PUBMED:16582901]
[PUBMED:8034711]
[PUBMED:8479536]
[PUBMED:10640739]
[PUBMED:3919143]
[PUBMED:10224278]
[PUBMED:10811865]
TNF receptor signaling pathway
[NCBI:138053]
[Pathway Interaction Database:tnfpathway]
[PUBMED:17024246]
[PUBMED:7923351]
[PUBMED:9774977]
[PUBMED:15258597]
[PUBMED:11429546]
[PUBMED:10848577]
[PUBMED:12917689]
[PUBMED:11031259]
[PUBMED:8974401]
[PUBMED:7758105]
[PUBMED:10510344]
[PUBMED:15793306]
[PUBMED:12391233]
[PUBMED:18450452]
[PUBMED:15218148]
[PUBMED:8692885]
[PUBMED:10026132]
[PUBMED:9275185]
[PUBMED:11684013]
[PUBMED:8521496]
[PUBMED:12917690]
[PUBMED:10795740]
[PUBMED:16603398]
[PUBMED:9405407]
[PUBMED:2158863]
[PUBMED:16260783]
[PUBMED:8808629]
[PUBMED:9034190]
[PUBMED:16543241]
[PUBMED:12077366]
[PUBMED:9384583]
[PUBMED:8612133]
[PUBMED:9712898]
[PUBMED:1313189]
[PUBMED:8069916]
[PUBMED:11907583]
[PUBMED:9639556]
[PUBMED:12917691]
[PUBMED:9115275]
[PUBMED:8681376]
[PUBMED:10356400]
[PUBMED:10801798]
[PUBMED:10097111]
[PUBMED:8565075]
[PUBMED:10187805]
[PUBMED:15357952]
[PUBMED:9915703]
[PUBMED:9564042]
[PUBMED:8943045]
TNF signaling
[NCBI:1269646]
[REACTOME:R-HSA-75893]
[PUBMED:12040173]
TNF signaling pathway
[NCBI:812256]
[KEGG:hsa04668]
[PUBMED:20489699]
[PUBMED:14532286]
[PUBMED:21232019]
[PUBMED:11897488]
[PUBMED:22296764]
[PUBMED:10581243]
[PUBMED:23085193]
[PUBMED:23531747]
TNFR1-induced NFkappaB signaling pathway
[NCBI:1309092]
[REACTOME:R-HSA-5357956]
[PUBMED:16603398]
[PUBMED:17306544]
TRAF6 mediated NF-kB activation
[NCBI:1269263]
[REACTOME:R-HSA-933542]
[PUBMED:18984593]
TRAF6 mediated induction of NFkB and MAP kinases upon TLR7/8 or 9 activation
[NCBI:1269229]
[REACTOME:R-HSA-975138]
[PUBMED:22511786]
[PUBMED:18794297]
TRAIL signaling pathway
[NCBI:137920]
[Pathway Interaction Database:trail_pathway]
[PUBMED:10958661]
[PUBMED:9430226]
[PUBMED:9311998]
[PUBMED:16227629]
[PUBMED:10521396]
[PUBMED:9242610]
[PUBMED:12668516]
[PUBMED:15105837]
[PUBMED:11461927]
[PUBMED:16319225]
[PUBMED:9082980]
[PUBMED:9430227]
[PUBMED:16980609]
[PUBMED:10894160]
[PUBMED:16940186]
[PUBMED:16636669]
[PUBMED:10783243]
[PUBMED:11278665]
[PUBMED:11376335]
[PUBMED:9314565]
[PUBMED:10521444]
[PUBMED:10894161]
TRIF-mediated TLR3/TLR4 signaling
[NCBI:1269221]
[REACTOME:R-HSA-937061]
[PUBMED:15814722]
[PUBMED:12855817]
[PUBMED:14739303]
Th1 and Th2 cell differentiation
[NCBI:1458885]
[KEGG:hsa04658]
[PUBMED:15819694]
[PUBMED:12171942]
[PUBMED:19165228]
[PUBMED:23336087]
[PUBMED:26044597]
[PUBMED:19151746]
[PUBMED:19362457]
[PUBMED:22044277]
[PUBMED:11752608]
[PUBMED:23405903]
[PUBMED:19375293]
[PUBMED:24113868]
[PUBMED:19151747]
[PUBMED:23624818]
[PUBMED:22566933]
[PUBMED:11121747]
[PUBMED:20969597]
[PUBMED:20065998]
Th17 cell differentiation
[NCBI:1469482]
[KEGG:hsa04659]
[PUBMED:23325835]
[PUBMED:23036716]
[PUBMED:20488727]
[PUBMED:21151104]
[PUBMED:21084214]
[PUBMED:20054607]
[PUBMED:22754770]
[PUBMED:22640807]
[PUBMED:19379825]
[PUBMED:22133865]
[PUBMED:22324470]
[PUBMED:17768419]
[PUBMED:18408735]
[PUBMED:21776333]
[PUBMED:26253381]
[PUBMED:16200068]
[PUBMED:18362914]
[PUBMED:24325586]
[PUBMED:19381306]
[PUBMED:18166487]
Toll Like Receptor 10 (TLR10) Cascade
[NCBI:1269206]
[REACTOME:R-HSA-168142]
[PUBMED:15728506]
[PUBMED:18332149]
Toll Like Receptor 2 (TLR2) Cascade
[NCBI:1269238]
[REACTOME:R-HSA-181438]
[PUBMED:10820283]
Toll Like Receptor 3 (TLR3) Cascade
[NCBI:1269219]
[REACTOME:R-HSA-168164]
[PUBMED:19627256]
[PUBMED:15733829]
[PUBMED:18202435]
Toll Like Receptor 4 (TLR4) Cascade
[NCBI:1269234]
[REACTOME:R-HSA-166016]
Toll Like Receptor 5 (TLR5) Cascade
[NCBI:1269226]
[REACTOME:R-HSA-168176]
[PUBMED:11489966]
[PUBMED:11323673]
Toll Like Receptor 7/8 (TLR7/8) Cascade
[NCBI:1269227]
[REACTOME:R-HSA-168181]
[PUBMED:14976262]
Toll Like Receptor 9 (TLR9) Cascade
[NCBI:1269233]
[REACTOME:R-HSA-168138]
[PUBMED:14751759]
Toll Like Receptor TLR1:TLR2 Cascade
[NCBI:1269239]
[REACTOME:R-HSA-168179]
[PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade
[NCBI:1269240]
[REACTOME:R-HSA-168188]
[PUBMED:14977973]
Toll-Like Receptors Cascades
[NCBI:1269204]
[REACTOME:R-HSA-168898]
[PUBMED:15950447]
[PUBMED:12893815]
[PUBMED:15976490]
[PUBMED:15585605]
[PUBMED:14751757]
Toll-like receptor signaling pathway
[NCBI:83076]
[KEGG:hsa04620]
[PUBMED:16924467]
[PUBMED:17395581]
[PUBMED:17637696]
[PUBMED:12734364]
[PUBMED:17507094]
[PUBMED:14698224]
[PUBMED:11101877]
[PUBMED:16497588]
[PUBMED:14751764]
[PUBMED:17275323]
[PUBMED:17457343]
[PUBMED:16932750]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Ub-specific processing proteases
[NCBI:1427862]
[REACTOME:R-HSA-5689880]
[PUBMED:16325574]
Viral carcinogenesis
[NCBI:658418]
[KEGG:hsa05203]
[PUBMED:9990017]
[PUBMED:15173177]
[PUBMED:16036567]
[PUBMED:16581947]
[PUBMED:9060639]
[PUBMED:17457345]
[PUBMED:15956361]
[PUBMED:21421561]
[PUBMED:18391203]
[PUBMED:21040832]
[PUBMED:9837909]
[PUBMED:17645777]
[PUBMED:15967719]
[PUBMED:12686421]
[PUBMED:17049016]
[PUBMED:21152115]
[PUBMED:11160754]
[PUBMED:21966251]
[PUBMED:17979705]
[PUBMED:8617242]
[PUBMED:12925958]
[PUBMED:10873631]
[PUBMED:21250384]
[PUBMED:15614436]
[PUBMED:10354594]
[PUBMED:20494113]
[PUBMED:18702816]
[PUBMED:9651361]
[PUBMED:16459163]
[PUBMED:11278402]
[PUBMED:15510157]
[PUBMED:19956178]
[PUBMED:18251977]
[PUBMED:11766888]
[PUBMED:10824878]
[PUBMED:21372216]
[PUBMED:11244044]
[PUBMED:17894800]
[PUBMED:11905817]
[PUBMED:21347341]
[PUBMED:12186904]
[PUBMED:9374493]
[PUBMED:16352731]
[PUBMED:12770701]
[PUBMED:17384582]
[PUBMED:14506283]
[PUBMED:11091847]
[PUBMED:17267064]
[PUBMED:11886269]
[PUBMED:21177815]
[PUBMED:10400746]
[PUBMED:19156753]
[PUBMED:9882379]
[PUBMED:14559998]
[PUBMED:15767449]
[PUBMED:22110506]
[PUBMED:20534855]
[PUBMED:15542638]
[PUBMED:9343405]
[PUBMED:10405893]
[PUBMED:19400863]
[PUBMED:9349482]
[PUBMED:14747563]
[PUBMED:21647825]
[PUBMED:12970441]
[PUBMED:11669605]
[PUBMED:15795286]
[PUBMED:21994562]
[PUBMED:14530271]
[PUBMED:9594662]
[PUBMED:22566809]
[PUBMED:19651473]
[PUBMED:8756622]
[PUBMED:15105524]
[PUBMED:15452270]
[PUBMED:18948197]
[PUBMED:16760382]
[PUBMED:10793105]
[PUBMED:21084867]
[PUBMED:16308315]
[PUBMED:16155604]
[PUBMED:16381817]
[PUBMED:16828973]
[PUBMED:15342967]
[PUBMED:15692053]
[PUBMED:10855768]
[PUBMED:19078975]
[PUBMED:12379483]
[PUBMED:15310405]
[PUBMED:8223437]
[PUBMED:16939421]
[PUBMED:12910250]
[PUBMED:16039586]
[PUBMED:18201576]
[PUBMED:21102637]
[PUBMED:21743832]
[PUBMED:20592731]
[PUBMED:10644344]
[PUBMED:10074132]
[PUBMED:19715458]
[PUBMED:16155601]
[PUBMED:11604508]
[PUBMED:15919895]
[PUBMED:11099494]
[PUBMED:18385245]
[PUBMED:19854353]
[PUBMED:12101418]
ZBP1(DAI) mediated induction of type I IFNs
[NCBI:1269269]
[REACTOME:R-HSA-1606322]
[PUBMED:18375758]
[PUBMED:18941233]
[PUBMED:11842111]
[PUBMED:19590578]
[PUBMED:17618271]
[PUBMED:18771559]
[PUBMED:19846511]
activated TAK1 mediates p38 MAPK activation
[NCBI:1269213]
[REACTOME:R-HSA-450302]
[PUBMED:10878576]
[PUBMED:8533096]
[PUBMED:15837794]
p75(NTR)-mediated signaling
[NCBI:138019]
[Pathway Interaction Database:p75ntrpathway]
[PUBMED:14673001]
[PUBMED:14593116]
[PUBMED:10545116]
[PUBMED:11729324]
[PUBMED:16252010]
[PUBMED:11756426]
[PUBMED:12414813]
[PUBMED:2157470]
[PUBMED:11777929]
[PUBMED:1547788]
[PUBMED:10764727]
[PUBMED:8614802]
[PUBMED:14960584]
[PUBMED:12376548]
[PUBMED:11756498]
[PUBMED:8079174]
[PUBMED:16498402]
[PUBMED:15051733]
[PUBMED:12682012]
[PUBMED:14638693]
[PUBMED:14966521]
[PUBMED:9915784]
[PUBMED:11487608]
[PUBMED:10485890]
[PUBMED:16630834]
[PUBMED:11312266]
[PUBMED:10985348]
[PUBMED:11244088]
[PUBMED:6093111]
[PUBMED:10595511]
[PUBMED:14985763]
[PUBMED:12097334]
[PUBMED:15548667]
[PUBMED:15470142]
[PUBMED:11279271]
[PUBMED:8878481]
[PUBMED:12422217]
[PUBMED:15987945]
[PUBMED:15668238]
[PUBMED:10433815]
[PUBMED:12692556]
[PUBMED:2025430]
[PUBMED:15930396]
[PUBMED:11278287]
[PUBMED:12034707]