full name
NLR family CARD domain containing 4
synonyms
CARD12, CLAN, CLAN1, CLANA, CLANB, CLANC, CLAND, CLR2.1, IPAF, NLRC4, ENSG00000091106
HGNC
HGNC:16412
Entrez Gene
Gene:58484
ENSEMBL
ENSG00000091106
location
chr: 2
start: 32449518
stop: 32490812
strand: -
OMIM
OMIM:606831:
NLRC4
OMIM:616115:
?Familial cold autoinflammatory syndrome 4
OMIM:616050:
Autoinflammation with infantile enterocolitis
transcripts
NM_021209.4
NM_001199139.1
NM_001199138.1
pathways
Direct p53 effectors
[NCBI:137939]
[Pathway Interaction Database:p53downstreampathway]
[PUBMED:7479001]
[PUBMED:19626115]
[PUBMED:10692390]
[PUBMED:15289308]
[PUBMED:14688482]
[PUBMED:16301995]
[PUBMED:11850816]
[PUBMED:12370809]
[PUBMED:16260627]
[PUBMED:15186775]
[PUBMED:15580302]
[PUBMED:10748162]
[PUBMED:10919640]
[PUBMED:19011621]
[PUBMED:12438652]
[PUBMED:11559530]
[PUBMED:11641774]
[PUBMED:11971958]
[PUBMED:9659898]
[PUBMED:9343394]
[PUBMED:10716435]
[PUBMED:17146433]
[PUBMED:17719542]
[PUBMED:17938176]
[PUBMED:17409421]
[PUBMED:11032029]
[PUBMED:15781865]
[PUBMED:11463392]
[PUBMED:9736732]
[PUBMED:17268548]
[PUBMED:8570655]
[PUBMED:18046411]
[PUBMED:12944906]
[PUBMED:16249378]
[PUBMED:15273740]
[PUBMED:15598651]
[PUBMED:10618379]
[PUBMED:15958553]
[PUBMED:17189187]
[PUBMED:17145718]
[PUBMED:11988847]
[PUBMED:8119988]
[PUBMED:12089322]
[PUBMED:16286009]
[PUBMED:12890671]
[PUBMED:12402042]
[PUBMED:10618714]
[PUBMED:14730312]
[PUBMED:12857899]
[PUBMED:14963330]
[PUBMED:11278953]
[PUBMED:11973653]
[PUBMED:12692263]
[PUBMED:10984493]
[PUBMED:10640990]
[PUBMED:11545734]
[PUBMED:16151013]
[PUBMED:12372430]
[PUBMED:16651407]
[PUBMED:9891062]
[PUBMED:12606722]
[PUBMED:12453409]
[PUBMED:15377670]
[PUBMED:12667443]
[PUBMED:17707234]
[PUBMED:9920903]
[PUBMED:14992722]
[PUBMED:15790310]
[PUBMED:15831478]
[PUBMED:11314010]
[PUBMED:10329733]
[PUBMED:17264218]
[PUBMED:11511362]
[PUBMED:11919562]
[PUBMED:11814693]
[PUBMED:17554199]
[PUBMED:18250150]
[PUBMED:10518217]
[PUBMED:10891498]
[PUBMED:10973264]
[PUBMED:15077116]
[PUBMED:16230375]
[PUBMED:18485870]
[PUBMED:7796420]
[PUBMED:15710382]
[PUBMED:17409411]
[PUBMED:8319905]
[PUBMED:10684646]
[PUBMED:7566179]
[PUBMED:8887630]
[PUBMED:11807984]
[PUBMED:9841917]
[PUBMED:12654245]
[PUBMED:9023107]
[PUBMED:15103385]
[PUBMED:11684014]
[PUBMED:17110336]
[PUBMED:11278253]
[PUBMED:14576823]
[PUBMED:8418500]
[PUBMED:11350971]
[PUBMED:11840333]
[PUBMED:7651818]
[PUBMED:7651386]
[PUBMED:15378026]
[PUBMED:15607964]
[PUBMED:11279192]
[PUBMED:10777218]
[PUBMED:15334053]
[PUBMED:12138177]
[PUBMED:9619826]
[PUBMED:16278683]
[PUBMED:17189186]
[PUBMED:16140933]
[PUBMED:10094469]
[PUBMED:9926927]
[PUBMED:17719541]
[PUBMED:15735003]
[PUBMED:12853982]
[PUBMED:14707288]
[PUBMED:10777207]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammasomes
[NCBI:1269253]
[REACTOME:R-HSA-622312]
[PUBMED:20303873]
[PUBMED:19120479]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Legionellosis
[NCBI:469200]
[KEGG:hsa05134]
[PUBMED:19021631]
[PUBMED:19157961]
[PUBMED:20375353]
[PUBMED:19478083]
[PUBMED:18284575]
[PUBMED:19386084]
[PUBMED:19666608]
[PUBMED:15972519]
[PUBMED:18549456]
[PUBMED:1721820]
[PUBMED:17124169]
[PUBMED:19687203]
[PUBMED:18363881]
[PUBMED:19343209]
[PUBMED:20941588]
[PUBMED:16824952]
[PUBMED:18281405]
[PUBMED:18048909]
[PUBMED:16495539]
[PUBMED:12427954]
NOD-like receptor signaling pathway
[NCBI:122191]
[KEGG:hsa04621]
[PUBMED:25330206]
[PUBMED:21575908]
[PUBMED:23846113]
[PUBMED:26549800]
[PUBMED:16493424]
[PUBMED:23124073]
[PUBMED:24840700]
[PUBMED:27291964]
[PUBMED:27012466]
[PUBMED:24707857]
[PUBMED:19767725]
[PUBMED:25879280]
[PUBMED:23215645]
[PUBMED:22819539]
[PUBMED:23702978]
[PUBMED:20643110]
[PUBMED:25879288]
[PUBMED:26655628]
[PUBMED:25145756]
[PUBMED:24718315]
[PUBMED:26482951]
[PUBMED:25526305]
[PUBMED:26121197]
[PUBMED:22430786]
Nucleotide-binding domain, leucine rich repeat containing receptor (NLR) signaling pathways
[NCBI:1269251]
[REACTOME:R-HSA-168643]
[PUBMED:18928408]
Salmonella infection
[NCBI:375172]
[KEGG:hsa05132]
[PUBMED:18407067]
[PUBMED:18411289]
[PUBMED:18778407]
[PUBMED:20123714]
[PUBMED:20158475]
[PUBMED:19779561]
[PUBMED:18026123]
[PUBMED:19930040]
[PUBMED:12675800]
[PUBMED:11755407]
[PUBMED:11489966]
[PUBMED:19775254]
[PUBMED:20943123]
[PUBMED:17690885]
[PUBMED:16938850]
[PUBMED:20526845]
[PUBMED:11567004]
[PUBMED:17074883]
[PUBMED:11825778]
[PUBMED:17071592]
[PUBMED:16800847]
[PUBMED:16611232]
[PUBMED:10499590]
TP53 Regulates Transcription of Caspase Activators and Caspases
[NCBI:1383069]
[REACTOME:R-HSA-6803207]
[PUBMED:15580302]
[PUBMED:14688482]
[PUBMED:10973264]
[PUBMED:11278253]
[PUBMED:12089322]
[PUBMED:11559530]
[PUBMED:17284521]
TP53 Regulates Transcription of Cell Death Genes
[NCBI:1383066]
[REACTOME:R-HSA-5633008]
[PUBMED:20353938]
[PUBMED:18676979]
[PUBMED:11511362]
[PUBMED:11919562]
[PUBMED:10973264]
[PUBMED:15797384]
[PUBMED:17442733]
[PUBMED:15607964]
[PUBMED:11278253]
[PUBMED:23059823]
[PUBMED:19549844]
[PUBMED:11684014]
[PUBMED:7566179]
[PUBMED:17349958]
[PUBMED:24739573]
[PUBMED:18719709]
[PUBMED:17284521]
[PUBMED:23703390]
[PUBMED:10807576]
[PUBMED:10733530]
[PUBMED:12402042]
[PUBMED:12851404]
[PUBMED:14729977]
[PUBMED:18431400]
[PUBMED:15377670]
[PUBMED:12089322]
[PUBMED:15273740]
[PUBMED:11382926]
[PUBMED:12606722]
[PUBMED:14623878]
[PUBMED:15577913]
[PUBMED:16230375]
[PUBMED:26122615]
[PUBMED:11559530]
[PUBMED:11054413]
[PUBMED:22766503]
[PUBMED:11463392]
[PUBMED:16249378]
[PUBMED:9326928]
[PUBMED:14614825]
[PUBMED:19615968]
[PUBMED:16140933]
[PUBMED:7834749]
[PUBMED:16135520]
[PUBMED:15126337]
[PUBMED:15580302]
[PUBMED:15289308]
[PUBMED:10777207]
[PUBMED:23365256]
[PUBMED:19040420]
[PUBMED:15735003]
[PUBMED:14688482]
The IPAF inflammasome
[NCBI:1269256]
[REACTOME:R-HSA-844623]
[PUBMED:20303873]
Transcriptional Regulation by TP53
[NCBI:1269654]
[REACTOME:R-HSA-3700989]
[PUBMED:26122615]
[PUBMED:19410540]
