Logo
full name
exportin 1

synonyms
CRM1, emb, exp1, XPO1, ENSG00000082898

HGNC
HGNC:12825

Entrez Gene
Gene:7514

ENSEMBL
ENSG00000082898

location
chr: 2
start: 61705069
stop: 61765440
strand: -

transcripts
NM_003400.3

pathways
Canonical NF-kappaB pathway [NCBI:138030] [Pathway Interaction Database:nfkappabcanonicalpathway] [PUBMED:7878466] [PUBMED:10688673] [PUBMED:16497931] [PUBMED:10755617] [PUBMED:9660950] [PUBMED:9346241] [PUBMED:10195894] [PUBMED:10521409] [PUBMED:12917691] [PUBMED:15620648] [PUBMED:14695475] [PUBMED:14651848] [PUBMED:11319224] [PUBMED:9150141] [PUBMED:9819420] [PUBMED:15218148] [PUBMED:7739562] [PUBMED:12657630] [PUBMED:12867425] [PUBMED:16267042]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic [NCBI:1269763] [REACTOME:R-HSA-69278]
Cyclin A/B1 associated events during G2/M transition [NCBI:1269800] [REACTOME:R-HSA-69273] [PUBMED:18228324]
Deactivation of the beta-catenin transactivating complex [NCBI:1269604] [REACTOME:R-HSA-3769402] [PUBMED:18632669] [PUBMED:12408825] [PUBMED:18573912] [PUBMED:11080158] [PUBMED:15525529] [PUBMED:16510874] [PUBMED:12712206] [PUBMED:18077326] [PUBMED:19364920] [PUBMED:12408824] [PUBMED:10898789]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Downregulation of TGF-beta receptor signaling [NCBI:1269525] [REACTOME:R-HSA-2173788] [PUBMED:10519551] [PUBMED:16027725] [PUBMED:9215638] [PUBMED:20937913] [PUBMED:20129061] [PUBMED:11158580] [PUBMED:9335507] [PUBMED:15781469] [PUBMED:12519765] [PUBMED:16061177] [PUBMED:10757800] [PUBMED:11278251] [PUBMED:12151385] [PUBMED:20061380] [PUBMED:22045334] [PUBMED:14701756] [PUBMED:15496141] [PUBMED:19758997] [PUBMED:14718519] [PUBMED:22344298] [PUBMED:11163210]
Epstein-Barr virus infection [NCBI:585562] [KEGG:hsa05169] [PUBMED:1658397] [PUBMED:10683340] [PUBMED:19375142] [PUBMED:12438576] [PUBMED:12910248] [PUBMED:10400785] [PUBMED:16007144] [PUBMED:14576817] [PUBMED:18559925] [PUBMED:16352731] [PUBMED:7895172] [PUBMED:15510157] [PUBMED:21518914] [PUBMED:10891508] [PUBMED:14673102] [PUBMED:17159145] [PUBMED:15542638] [PUBMED:18786993] [PUBMED:16603506] [PUBMED:10644367] [PUBMED:15021898] [PUBMED:10666279] [PUBMED:9565632]
Export of Viral Ribonucleoproteins from Nucleus [NCBI:1269121] [REACTOME:R-HSA-168274] [PUBMED:11118210] [PUBMED:17081640] [PUBMED:16806605]
FoxO family signaling [NCBI:138036] [Pathway Interaction Database:foxopathway] [PUBMED:17038621] [PUBMED:15788402] [PUBMED:14976264] [PUBMED:11864996] [PUBMED:12517744] [PUBMED:11050388] [PUBMED:10960473] [PUBMED:10783894] [PUBMED:11154281] [PUBMED:11313479] [PUBMED:11777915] [PUBMED:11980723] [PUBMED:10102273] [PUBMED:15509806] [PUBMED:11237865] [PUBMED:16751106] [PUBMED:12857750] [PUBMED:15538382] [PUBMED:12239572] [PUBMED:12048180] [PUBMED:11884717] [PUBMED:11884591] [PUBMED:15084260] [PUBMED:11964479] [PUBMED:10217147] [PUBMED:15109499] [PUBMED:16964248] [PUBMED:15905404] [PUBMED:11607034] [PUBMED:15668399] [PUBMED:15220471] [PUBMED:10358075] [PUBMED:16424905]
G2/M Transition [NCBI:1269799] [REACTOME:R-HSA-69275]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
HIV Life Cycle [NCBI:1269058] [REACTOME:R-HSA-162587] [PUBMED:9188609] [PUBMED:9759480]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
Hedgehog signaling events mediated by Gli proteins [NCBI:137912] [Pathway Interaction Database:hedgehog_glipathway] [PUBMED:14611647] [PUBMED:16908539] [PUBMED:16885213] [PUBMED:16459297] [PUBMED:15087129] [PUBMED:10075717] [PUBMED:10725236] [PUBMED:10564661] [PUBMED:15215207] [PUBMED:16611981] [PUBMED:16364285] [PUBMED:11748151] [PUBMED:16537363] [PUBMED:10531011] [PUBMED:11449277] [PUBMED:12812795] [PUBMED:16424016] [PUBMED:14723851] [PUBMED:10693759] [PUBMED:15545630] [PUBMED:16254602] [PUBMED:14603322] [PUBMED:16061793] [PUBMED:10559945] [PUBMED:16740475] [PUBMED:16705181] [PUBMED:9636069] [PUBMED:10806483] [PUBMED:11960000] [PUBMED:15930098]
Host Interactions of HIV factors [NCBI:1269091] [REACTOME:R-HSA-162909]
HuR (ELAVL1) binds and stabilizes mRNA [NCBI:1269730] [REACTOME:R-HSA-450520] [PUBMED:12704645] [PUBMED:12440953] [PUBMED:18285462] [PUBMED:17392515] [PUBMED:14976220] [PUBMED:16391004]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Influenza Infection [NCBI:1269108] [REACTOME:R-HSA-168254]
Influenza Life Cycle [NCBI:1269109] [REACTOME:R-HSA-168255]
Interactions of Rev with host cellular proteins [NCBI:1269095] [REACTOME:R-HSA-177243] [PUBMED:9837918]
Late Phase of HIV Life Cycle [NCBI:1269069] [REACTOME:R-HSA-162599] [PUBMED:2825027] [PUBMED:10550206] [PUBMED:10562489] [PUBMED:15719065] [PUBMED:15183343] [PUBMED:3031512] [PUBMED:9891806] [PUBMED:2784194]
M Phase [NCBI:1269810] [REACTOME:R-HSA-68886]
MAPK family signaling cascades [NCBI:1269501] [REACTOME:R-HSA-5683057] [PUBMED:21167873] [PUBMED:17161475] [PUBMED:22535895] [PUBMED:21372320]
MAPK6/MAPK4 signaling [NCBI:1269506] [REACTOME:R-HSA-5687128] [PUBMED:18644862] [PUBMED:22800433] [PUBMED:19166925] [PUBMED:12808096] [PUBMED:18248330] [PUBMED:20849292] [PUBMED:21329875] [PUBMED:21177870] [PUBMED:17161475] [PUBMED:18593949] [PUBMED:21372320] [PUBMED:18720373] [PUBMED:17947239] [PUBMED:15226418] [PUBMED:22505454]
Mitotic Anaphase [NCBI:1269825] [REACTOME:R-HSA-68882]
Mitotic G2-G2/M phases [NCBI:1269797] [REACTOME:R-HSA-453274]
Mitotic Metaphase and Anaphase [NCBI:1269823] [REACTOME:R-HSA-2555396]
Mitotic Prometaphase [NCBI:1269820] [REACTOME:R-HSA-68877]
NEP/NS2 Interacts with the Cellular Export Machinery [NCBI:1269123] [REACTOME:R-HSA-168333] [PUBMED:17081640] [PUBMED:11118210] [PUBMED:12970177]
RHO GTPase Effectors [NCBI:1269509] [REACTOME:R-HSA-195258] [PUBMED:9694656] [PUBMED:18066052] [PUBMED:11018042] [PUBMED:10470034] [PUBMED:8702756] [PUBMED:21730051] [PUBMED:8571126] [PUBMED:19513348] [PUBMED:17244649] [PUBMED:11145705] [PUBMED:24128008] [PUBMED:23716662] [PUBMED:8617235] [PUBMED:8543060] [PUBMED:11804587] [PUBMED:24969695] [PUBMED:12635176] [PUBMED:12778124] [PUBMED:18006505] [PUBMED:1660188] [PUBMED:21351730] [PUBMED:16507994] [PUBMED:14595335] [PUBMED:10072071] [PUBMED:10591629] [PUBMED:10753910] [PUBMED:23875749] [PUBMED:17151359] [PUBMED:10652353] [PUBMED:12221077] [PUBMED:10559936] [PUBMED:12783890] [PUBMED:11948177] [PUBMED:18237546] [PUBMED:16079795] [PUBMED:10924361] [PUBMED:14514689] [PUBMED:8107774] [PUBMED:8756646] [PUBMED:16979770] [PUBMED:16636067] [PUBMED:9751706] [PUBMED:10619026] [PUBMED:23444367] [PUBMED:15546864] [PUBMED:12473120] [PUBMED:8816443] [PUBMED:9199170] [PUBMED:12514133] [PUBMED:16762923] [PUBMED:12110184] [PUBMED:16431929] [PUBMED:10975528] [PUBMED:10940294] [PUBMED:9535855] [PUBMED:7559638] [PUBMED:11162552] [PUBMED:19737400] [PUBMED:9988689] [PUBMED:12732141] [PUBMED:8798539] [PUBMED:24914801] [PUBMED:11689693] [PUBMED:8769096] [PUBMED:9368021]
RHO GTPases Activate Formins [NCBI:1269519] [REACTOME:R-HSA-5663220] [PUBMED:20233848] [PUBMED:15507212] [PUBMED:16292343] [PUBMED:12906795] [PUBMED:11779461] [PUBMED:21397845] [PUBMED:12577064] [PUBMED:17198702] [PUBMED:15006353] [PUBMED:20101212] [PUBMED:15944396] [PUBMED:10678165] [PUBMED:16943183] [PUBMED:16439214] [PUBMED:16472745] [PUBMED:10958683] [PUBMED:12732141] [PUBMED:15085137] [PUBMED:24914801] [PUBMED:9497258] [PUBMED:21576392] [PUBMED:21868368]
RNA transport [NCBI:177876] [KEGG:hsa03013] [PUBMED:10872469] [PUBMED:17401408] [PUBMED:20733056] [PUBMED:11018020] [PUBMED:15519698] [PUBMED:16314458] [PUBMED:15901496] [PUBMED:9548260] [PUBMED:18313922]
Regulation of Wnt-mediated beta catenin signaling and target gene transcription [NCBI:169352] [Pathway Interaction Database:wnt_beta_catenin_pathway] [PUBMED:19901072] [PUBMED:19699733] [PUBMED:15142975] [PUBMED:16565090] [PUBMED:17372190] [PUBMED:17310985] [PUBMED:11751639] [PUBMED:16301527] [PUBMED:10921920] [PUBMED:8622675] [PUBMED:19571879] [PUBMED:11445543] [PUBMED:19066453] [PUBMED:15768032] [PUBMED:10704849] [PUBMED:19940019] [PUBMED:15378020] [PUBMED:10318916] [PUBMED:10617567] [PUBMED:19435523] [PUBMED:18511409] [PUBMED:18006687] [PUBMED:14638683] [PUBMED:15782138] [PUBMED:15143193] [PUBMED:9671490] [PUBMED:11263497] [PUBMED:18193033] [PUBMED:9751710] [PUBMED:11532957] [PUBMED:10898789] [PUBMED:11266540] [PUBMED:17090534] [PUBMED:15492215] [PUBMED:16309666] [PUBMED:12502739] [PUBMED:10980707] [PUBMED:17945188] [PUBMED:11572874] [PUBMED:11809808] [PUBMED:17113388] [PUBMED:20128690] [PUBMED:17709391] [PUBMED:11500377] [PUBMED:12464179] [PUBMED:18347071] [PUBMED:18347094] [PUBMED:15592430] [PUBMED:10958684] [PUBMED:12408825] [PUBMED:15525529] [PUBMED:16581771] [PUBMED:12052822] [PUBMED:15668231] [PUBMED:16014379] [PUBMED:17923689] [PUBMED:15592505] [PUBMED:10984057] [PUBMED:20044351] [PUBMED:11940574] [PUBMED:10747853] [PUBMED:12606575] [PUBMED:15728254] [PUBMED:11080158] [PUBMED:12446687] [PUBMED:20128911] [PUBMED:19816403] [PUBMED:18573912] [PUBMED:17397822] [PUBMED:10489374] [PUBMED:17052462] [PUBMED:20371816] [PUBMED:18347063] [PUBMED:11035805] [PUBMED:11792709] [PUBMED:16899215] [PUBMED:10882123] [PUBMED:12200448] [PUBMED:15060161] [PUBMED:12711682] [PUBMED:12582159] [PUBMED:12646922] [PUBMED:19460168] [PUBMED:16778892] [PUBMED:17306568] [PUBMED:12712206] [PUBMED:19711354] [PUBMED:17893322] [PUBMED:10934025] [PUBMED:19503085] [PUBMED:19433865]
Regulation of mRNA stability by proteins that bind AU-rich elements [NCBI:1269725] [REACTOME:R-HSA-450531] [PUBMED:12440953] [PUBMED:12704645] [PUBMED:15460540] [PUBMED:16391004]
Resolution of Sister Chromatid Cohesion [NCBI:1269821] [REACTOME:R-HSA-2500257] [PUBMED:16541025] [PUBMED:15339662] [PUBMED:17112726] [PUBMED:9649503] [PUBMED:21111234] [PUBMED:15737063] [PUBMED:17113138] [PUBMED:21987589] [PUBMED:14730319] [PUBMED:11509732] [PUBMED:19696148] [PUBMED:21878504] [PUBMED:15723797]
Rev-mediated nuclear export of HIV RNA [NCBI:1269085] [REACTOME:R-HSA-165054] [PUBMED:12932730] [PUBMED:8805303] [PUBMED:9791012]
Ribosome biogenesis in eukaryotes [NCBI:199378] [KEGG:hsa03008] [PUBMED:19879902] [PUBMED:19850913] [PUBMED:15120992] [PUBMED:17515605] [PUBMED:20174677]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
Separation of Sister Chromatids [NCBI:1269826] [REACTOME:R-HSA-2467813] [PUBMED:11081627] [PUBMED:10411507] [PUBMED:12070128] [PUBMED:12194817] [PUBMED:11509732]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Rho GTPases [NCBI:1269507] [REACTOME:R-HSA-194315] [PUBMED:16212495] [PUBMED:15630019]
Signaling by TGF-beta Receptor Complex [NCBI:1269523] [REACTOME:R-HSA-170834] [PUBMED:19648010]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Signaling events mediated by HDAC Class I [NCBI:137997] [Pathway Interaction Database:hdac_classi_pathway] [PUBMED:9885572] [PUBMED:14701748] [PUBMED:10888618] [PUBMED:12393750] [PUBMED:9804427] [PUBMED:9139820] [PUBMED:12408818] [PUBMED:16809764] [PUBMED:12788099] [PUBMED:11533489] [PUBMED:15831498] [PUBMED:15701600] [PUBMED:11532945] [PUBMED:12183469] [PUBMED:16428440] [PUBMED:9150134] [PUBMED:12972430] [PUBMED:11486036] [PUBMED:15920470] [PUBMED:9150135] [PUBMED:9651585] [PUBMED:11960997] [PUBMED:9326634] [PUBMED:11278251] [PUBMED:14521922] [PUBMED:9197243] [PUBMED:9346952] [PUBMED:16371367] [PUBMED:10444591] [PUBMED:15653507] [PUBMED:15920471] [PUBMED:11919195]
Signaling events mediated by HDAC Class II [NCBI:138062] [Pathway Interaction Database:hdac_classii_pathway] [PUBMED:15916966] [PUBMED:10869435] [PUBMED:10898795] [PUBMED:16051668] [PUBMED:12032081] [PUBMED:12606581] [PUBMED:11804585] [PUBMED:11466315] [PUBMED:11567998] [PUBMED:16767219] [PUBMED:12024216] [PUBMED:16166628] [PUBMED:16221676] [PUBMED:11948178] [PUBMED:10220385] [PUBMED:12663674] [PUBMED:14668799] [PUBMED:16236793]
Sumoylation by RanBP2 regulates transcriptional repression [NCBI:138029] [Pathway Interaction Database:ranbp2pathway] [PUBMED:11960997] [PUBMED:12393906] [PUBMED:8978815] [PUBMED:9456312] [PUBMED:12032081] [PUBMED:9019411] [PUBMED:9427648] [PUBMED:9108047] [PUBMED:12393750] [PUBMED:10892746] [PUBMED:9323132] [PUBMED:10454574]
TCF dependent signaling in response to WNT [NCBI:1269599] [REACTOME:R-HSA-201681] [PUBMED:19619488] [PUBMED:23256519] [PUBMED:23343194]
TGF-beta receptor signaling activates SMADs [NCBI:1269524] [REACTOME:R-HSA-2173789] [PUBMED:9346966] [PUBMED:15350224] [PUBMED:7737999] [PUBMED:11100470] [PUBMED:7693660] [PUBMED:9670020] [PUBMED:15564041] [PUBMED:9233797] [PUBMED:20207738] [PUBMED:11779505] [PUBMED:18243111] [PUBMED:8947046] [PUBMED:1333888] [PUBMED:9311995] [PUBMED:12482908] [PUBMED:8980228] [PUBMED:8242743] [PUBMED:9865696] [PUBMED:8047140] [PUBMED:21423151]