full name
dolichyl-diphosphooligosaccharide--protein glycosyltransferase non-catalytic subunit

synonyms
AGER1, CDG1R, OKSWcl45, OST, OST48, WBP1, DDOST, ENSG00000244038

HGNC
HGNC:2728

Entrez Gene
Gene:1650

ENSEMBL
ENSG00000244038

location
chr: 1
start: 20978260
stop: 20988037
strand: -

OMIM
OMIM:602202: DDOST (Autosomal recessive inheritance)
OMIM:614507: ?Congenital disorder of glycosylation, type Ir

transcripts
ENST00000415136

pathways
AGE/RAGE pathway [NCBI:698754] [WikiPathways:WP2324] [PUBMED:20681653] [PUBMED:15590648] [PUBMED:15020646] [PUBMED:15039226] [PUBMED:21829704]
Advanced glycosylation endproduct receptor signaling [NCBI:1269258] [REACTOME:R-HSA-879415] [PUBMED:16133426]
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:16807922] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
N-Glycan biosynthesis [NCBI:82975] [KEGG:hsa00510] [PUBMED:16878994] [PUBMED:12684507] [PUBMED:9111134] [PUBMED:11278778] [PUBMED:12200473] [PUBMED:15987956]
N-glycosylation by oligosaccharyltransferase [NCBI:413373] [KEGG:hsa_M00072]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:19491040] [PUBMED:20219571] [PUBMED:20112977]
SRP-dependent cotranslational protein targeting to membrane [NCBI:1268689] [REACTOME:R-HSA-1799339]
Translation [NCBI:1268678] [REACTOME:R-HSA-72766]