full name
mannosyl-oligosaccharide glucosidase

synonyms
CDG2B, CWH41, DER7, GCS1, MOGS, ENSG00000115275

HGNC
HGNC:24862

Entrez Gene
Gene:7841

ENSEMBL
ENSG00000115275

location
chr: 2
start: 74688184
stop: 74692537
strand: -

OMIM
OMIM:601336: MOGS (Autosomal recessive inheritance)
OMIM:606056: Congenital disorder of glycosylation, type IIb

transcripts
NM_001146158.1
NM_006302.2

pathways
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
N-Glycan biosynthesis [NCBI:82975] [KEGG:hsa00510] [PUBMED:12684507] [PUBMED:16878994] [PUBMED:11278778] [PUBMED:9111134] [PUBMED:12200473] [PUBMED:15987956]
N-glycan precursor trimming [NCBI:413374] [KEGG:hsa_M00073]
N-glycan trimming in the ER and Calnexin/Calreticulin cycle [NCBI:1268722] [REACTOME:R-HSA-532668] [PUBMED:18303019]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]