full name
hexokinase 2

synonyms
HKII, HXK2, HK2, ENSG00000159399

HGNC
HGNC:4923

Entrez Gene
Gene:3099

ENSEMBL
ENSG00000159399

location
chr: 2
start: 75059782
stop: 75120481
strand: +

transcripts
NM_000189.4

pathways
Amino sugar and nucleotide sugar metabolism [NCBI:82979] [KEGG:hsa00520] [PUBMED:16995900] [PUBMED:15134748] [PUBMED:11479276] [PUBMED:10984043] [PUBMED:16237198] [PUBMED:18199744] [PUBMED:15809294] [PUBMED:8071227] [PUBMED:14450717] [PUBMED:2793832] [PUBMED:16277754] [PUBMED:10931327] [PUBMED:17827295] [PUBMED:15695810] [PUBMED:18304669] [PUBMED:9811644] [PUBMED:11447132] [PUBMED:8444803] [PUBMED:12562791] [PUBMED:17190829] [PUBMED:17085508] [PUBMED:15489439] [PUBMED:16452451]
Carbohydrate digestion and absorption [NCBI:170720] [KEGG:hsa04973] [PUBMED:11562503] [PUBMED:19001049] [PUBMED:12512027] [PUBMED:5089892] [PUBMED:12583961] [PUBMED:7555019] [PUBMED:11427691] [PUBMED:12750891] [PUBMED:16186415] [PUBMED:20522896] [PUBMED:16586532] [PUBMED:15546855] [PUBMED:17222166] [PUBMED:18393659] [PUBMED:14642859]
Carbon metabolism [NCBI:814926] [KEGG:hsa01200]
Central carbon metabolism in cancer [NCBI:1059538] [KEGG:hsa05230] [PUBMED:16982728] [PUBMED:21127244] [PUBMED:22349059] [PUBMED:19270154] [PUBMED:24113830] [PUBMED:22156302] [PUBMED:21801601] [PUBMED:15916903] [PUBMED:18177721] [PUBMED:22237205] [PUBMED:20520704] [PUBMED:23018234] [PUBMED:23897900] [PUBMED:24398961] [PUBMED:24079832] [PUBMED:18538731] [PUBMED:19460998] [PUBMED:22307140] [PUBMED:18766298] [PUBMED:22101401] [PUBMED:23071355] [PUBMED:21508971] [PUBMED:24738035] [PUBMED:22750268] [PUBMED:21258394] [PUBMED:23279446] [PUBMED:21340684]
Fructose and mannose metabolism [NCBI:82930] [KEGG:hsa00051]
Galactose metabolism [NCBI:82931] [KEGG:hsa00052]
Glucose metabolism [NCBI:1269959] [REACTOME:R-HSA-70326]
Glucose transport [NCBI:1269921] [REACTOME:R-HSA-70153] [PUBMED:11780753]
Glycolysis [NCBI:1269960] [REACTOME:R-HSA-70171] [PUBMED:16051738]
Glycolysis (Embden-Meyerhof pathway), glucose => pyruvate [NCBI:413340] [KEGG:hsa_M00001]
Glycolysis / Gluconeogenesis [NCBI:82926] [KEGG:hsa00010]
HIF-1 signaling pathway [NCBI:695200] [KEGG:hsa04066] [PUBMED:11902584] [PUBMED:20965423] [PUBMED:20679415] [PUBMED:15031665] [PUBMED:18259201] [PUBMED:22205687] [PUBMED:19364912] [PUBMED:19147540] [PUBMED:15448722] [PUBMED:16234508] [PUBMED:18505681] [PUBMED:20836033] [PUBMED:19861159] [PUBMED:17955264] [PUBMED:22562152]
HIF-1-alpha transcription factor network [NCBI:138045] [Pathway Interaction Database:hif1_tfpathway] [PUBMED:11707426] [PUBMED:9242677] [PUBMED:9038135] [PUBMED:15310764] [PUBMED:11278891] [PUBMED:8816435] [PUBMED:8663540] [PUBMED:15235127] [PUBMED:12042299] [PUBMED:15312748] [PUBMED:14612449] [PUBMED:11342587] [PUBMED:12615703] [PUBMED:9632793] [PUBMED:12228247] [PUBMED:15044468] [PUBMED:8408001] [PUBMED:9822602] [PUBMED:15252039] [PUBMED:13679920] [PUBMED:11877282] [PUBMED:15235597] [PUBMED:15199161] [PUBMED:15104534] [PUBMED:10594042] [PUBMED:12354771] [PUBMED:10446188] [PUBMED:9436976] [PUBMED:11823643] [PUBMED:12370277] [PUBMED:8955077] [PUBMED:12879018] [PUBMED:14645546] [PUBMED:9486205] [PUBMED:9887100] [PUBMED:8089148] [PUBMED:15466858] [PUBMED:11708773] [PUBMED:15611046] [PUBMED:14742449] [PUBMED:15280364] [PUBMED:12215445] [PUBMED:15611089] [PUBMED:10777486] [PUBMED:9707622] [PUBMED:8917528] [PUBMED:15563275] [PUBMED:12067980] [PUBMED:10353251]
Hexose transport [NCBI:1269920] [REACTOME:R-HSA-189200] [PUBMED:16186415] [PUBMED:15546855]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:11742412] [PUBMED:11343120] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:10567225] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:15624019] [PUBMED:9445476] [PUBMED:9346240] [PUBMED:14635525] [PUBMED:16288289] [PUBMED:12867054] [PUBMED:15229476] [PUBMED:17344645] [PUBMED:9609111]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Neomycin, kanamycin and gentamicin biosynthesis [NCBI:145809] [KEGG:hsa00524] [PUBMED:17462573] [PUBMED:23179168] [PUBMED:15975512] [PUBMED:17226887] [PUBMED:19644520] [PUBMED:27120352] [PUBMED:17879343] [PUBMED:16506694] [PUBMED:25600434] [PUBMED:18685777] [PUBMED:18550838] [PUBMED:23679096] [PUBMED:21983602] [PUBMED:19362652] [PUBMED:12374384] [PUBMED:18311744] [PUBMED:21689223] [PUBMED:18001019] [PUBMED:19466609] [PUBMED:26083124] [PUBMED:26455715] [PUBMED:17482823] [PUBMED:18802637] [PUBMED:18672902] [PUBMED:25641167] [PUBMED:12870817] [PUBMED:15839685] [PUBMED:24746560] [PUBMED:17119636]
Nucleotide sugar biosynthesis, glucose => UDP-glucose [NCBI:664436] [KEGG:hsa_M00549]
SLC-mediated transmembrane transport [NCBI:1269907] [REACTOME:R-HSA-425407] [PUBMED:14624363] [PUBMED:19164095]
Starch and sucrose metabolism [NCBI:82974] [KEGG:hsa00500]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Type II diabetes mellitus [NCBI:83094] [KEGG:hsa04930] [PUBMED:12480546] [PUBMED:15759102] [PUBMED:9011569] [PUBMED:11078440] [PUBMED:11390407] [PUBMED:15258147] [PUBMED:15823385] [PUBMED:11272200] [PUBMED:11325516] [PUBMED:15733744] [PUBMED:9974390] [PUBMED:7491105] [PUBMED:15585596]