full name
RNA polymerase I subunit A

synonyms
A190, RPA1, RPA194, RPO1-4, RPO14, POLR1A, ENSG00000068654

HGNC
HGNC:17264

Entrez Gene
Gene:25885

ENSEMBL
ENSG00000068654

location
chr: 2
start: 86253451
stop: 86333278
strand: -

OMIM
OMIM:616404: POLR1A
OMIM:616462: Acrofacial dysostosis, Cincinnati type

transcripts
NM_015425.3

pathways
B-WICH complex positively regulates rRNA expression [NCBI:1339126] [REACTOME:R-HSA-5250924] [PUBMED:23555303] [PUBMED:21559432] [PUBMED:16514417] [PUBMED:23667505] [PUBMED:16603771] [PUBMED:16574391]
Epigenetic regulation of gene expression [NCBI:1269734] [REACTOME:R-HSA-212165] [PUBMED:12610534]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Negative epigenetic regulation of rRNA expression [NCBI:1269737] [REACTOME:R-HSA-5250941] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
NoRC negatively regulates rRNA expression [NCBI:1269739] [REACTOME:R-HSA-427413] [PUBMED:17439825] [PUBMED:17613545] [PUBMED:23063748] [PUBMED:11583633] [PUBMED:18631128] [PUBMED:18616426]
Positive epigenetic regulation of rRNA expression [NCBI:1339125] [REACTOME:R-HSA-5250913] [PUBMED:23153826] [PUBMED:16574391] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
Purine metabolism [NCBI:82944] [KEGG:hsa00230] [NCBI:1270134] [REACTOME:R-HSA-73847] [PUBMED:4620886] [PUBMED:10986234] [PUBMED:10601204]
Pyrimidine metabolism [NCBI:82946] [KEGG:hsa00240] [NCBI:1270138] [REACTOME:R-HSA-73848] [PUBMED:16098809]
RNA Polymerase I Chain Elongation [NCBI:1269662] [REACTOME:R-HSA-73777]
RNA Polymerase I Promoter Clearance [NCBI:1269658] [REACTOME:R-HSA-73854]
RNA Polymerase I Promoter Escape [NCBI:1269661] [REACTOME:R-HSA-73772]
RNA Polymerase I Transcription [NCBI:1269657] [REACTOME:R-HSA-73864]
RNA Polymerase I Transcription Initiation [NCBI:1269660] [REACTOME:R-HSA-73762]
RNA Polymerase I Transcription Termination [NCBI:1269663] [REACTOME:R-HSA-73863]
RNA Polymerase I, RNA Polymerase III, and Mitochondrial Transcription [NCBI:1269656] [REACTOME:R-HSA-504046]
RNA polymerase [NCBI:83037] [KEGG:hsa03020] [PUBMED:19880312] [PUBMED:10499798] [PUBMED:18573085] [PUBMED:10784442]