full name
alkaline phosphatase, liver/bone/kidney

synonyms
AP-TNAP, APTNAP, HOPS, TNAP, TNSALP, ALPL, ENSG00000162551

HGNC
HGNC:438

Entrez Gene
Gene:249

ENSEMBL
ENSG00000162551

location
chr: 1
start: 21835475
stop: 21904905
strand: +

OMIM
OMIM:171760: ALPL (Autosomal dominant inheritance,Autosomal recessive inheritance)
OMIM:146300: Hypophosphatasia, adult
OMIM:241510: Hypophosphatasia, childhood
OMIM:241500: Hypophosphatasia, infantile
OMIM:146300: Odontohypophosphatasia

transcripts
NM_000478.4
NM_001127501.2
NM_001177520.1

pathways
AGE/RAGE pathway [NCBI:698754] [WikiPathways:WP2324] [PUBMED:20681653] [PUBMED:15590648] [PUBMED:15020646] [PUBMED:15039226] [PUBMED:21829704]
BDNF signaling pathway [NCBI:712093] [WikiPathways:WP2380] [PUBMED:11980901] [PUBMED:8760293] [PUBMED:11922610] [PUBMED:18422784] [PUBMED:7780132] [PUBMED:11054408] [PUBMED:15504554] [PUBMED:12036856] [PUBMED:17658515] [PUBMED:11722433] [PUBMED:22809535] [PUBMED:20870899] [PUBMED:9070265] [PUBMED:9506832] [PUBMED:10979953] [PUBMED:9305885] [PUBMED:15701720] [PUBMED:8695859] [PUBMED:11204567] [PUBMED:15588513] [PUBMED:19261614] [PUBMED:10611229] [PUBMED:7589510] [PUBMED:10651727] [PUBMED:9711904] [PUBMED:10224114] [PUBMED:16123382] [PUBMED:9373250] [PUBMED:12855555] [PUBMED:11085749] [PUBMED:11750880] [PUBMED:10918061] [PUBMED:9257862] [PUBMED:18256550] [PUBMED:10460590] [PUBMED:21898686] [PUBMED:16368886] [PUBMED:18528423] [PUBMED:10415383] [PUBMED:22456226] [PUBMED:11784712] [PUBMED:11278373] [PUBMED:15673499] [PUBMED:14576181] [PUBMED:21304100] [PUBMED:18618018] [PUBMED:14687665] [PUBMED:10438715] [PUBMED:12495897] [PUBMED:19744539] [PUBMED:7795229] [PUBMED:9119889] [PUBMED:8632906] [PUBMED:11402314] [PUBMED:8843545] [PUBMED:21892137] [PUBMED:7545904] [PUBMED:19289146] [PUBMED:20576130] [PUBMED:18804163] [PUBMED:19888469] [PUBMED:8695851] [PUBMED:10419886] [PUBMED:19714753] [PUBMED:11238104] [PUBMED:11266445] [PUBMED:15705785] [PUBMED:16249382] [PUBMED:19038790] [PUBMED:15778351] [PUBMED:22514603] [PUBMED:9632812] [PUBMED:9446641] [PUBMED:9990315] [PUBMED:11861812] [PUBMED:20838657] [PUBMED:19619605] [PUBMED:11830463] [PUBMED:17244674] [PUBMED:8877093] [PUBMED:11418622] [PUBMED:9654143] [PUBMED:9111365] [PUBMED:21490406] [PUBMED:9396763] [PUBMED:15001470] [PUBMED:10477685] [PUBMED:11567993] [PUBMED:11376873] [PUBMED:15863506] [PUBMED:10090948] [PUBMED:21900501] [PUBMED:11429396] [PUBMED:18060035] [PUBMED:19631713] [PUBMED:11756417] [PUBMED:9120001] [PUBMED:8628315] [PUBMED:11110685] [PUBMED:11500082] [PUBMED:21630326] [PUBMED:15271795] [PUBMED:17021950] [PUBMED:10194437] [PUBMED:11389697] [PUBMED:10361118] [PUBMED:11535599] [PUBMED:9475764] [PUBMED:7649975] [PUBMED:22649382] [PUBMED:9002950] [PUBMED:10803464] [PUBMED:16418722] [PUBMED:18796624] [PUBMED:15671147] [PUBMED:11446731] [PUBMED:19996410] [PUBMED:20502002] [PUBMED:17284614] [PUBMED:9679986] [PUBMED:20586925] [PUBMED:12032335] [PUBMED:20335227] [PUBMED:8549784] [PUBMED:20976181] [PUBMED:10321988] [PUBMED:17827152] [PUBMED:18288130] [PUBMED:9108397] [PUBMED:18456388] [PUBMED:14617636] [PUBMED:10681535] [PUBMED:11934880] [PUBMED:7488109] [PUBMED:17925492] [PUBMED:15642952] [PUBMED:12359731] [PUBMED:10205146] [PUBMED:21853157] [PUBMED:12145691] [PUBMED:16115772] [PUBMED:21325822] [PUBMED:11012189] [PUBMED:9663467] [PUBMED:9108383] [PUBMED:21933853] [PUBMED:8978680] [PUBMED:18487512] [PUBMED:22005786] [PUBMED:11309383] [PUBMED:11964286] [PUBMED:15085152] [PUBMED:17980909] [PUBMED:9731041] [PUBMED:22528490] [PUBMED:10515871] [PUBMED:21527831] [PUBMED:17525997] [PUBMED:6325330] [PUBMED:20113333] [PUBMED:11283246] [PUBMED:17637498] [PUBMED:14662334] [PUBMED:10050883] [PUBMED:14576068] [PUBMED:7492761] [PUBMED:22128142] [PUBMED:9122198] [PUBMED:8555464] [PUBMED:10397715] [PUBMED:11478766] [PUBMED:11356906] [PUBMED:18632638] [PUBMED:10720694] [PUBMED:17550780] [PUBMED:8943867] [PUBMED:12101178] [PUBMED:17389006] [PUBMED:9845531] [PUBMED:18773906] [PUBMED:10216087] [PUBMED:7537762] [PUBMED:15271793] [PUBMED:12389630] [PUBMED:8639892] [PUBMED:8202160] [PUBMED:15337790] [PUBMED:16449323] [PUBMED:22101255] [PUBMED:22628264] [PUBMED:17455223] [PUBMED:7796811] [PUBMED:18075837] [PUBMED:14693160] [PUBMED:14500680] [PUBMED:9012841] [PUBMED:6286773] [PUBMED:2830276] [PUBMED:9630621] [PUBMED:11097834] [PUBMED:9166841] [PUBMED:14726379] [PUBMED:9657746] [PUBMED:12006617] [PUBMED:19844195] [PUBMED:9028319] [PUBMED:7534285] [PUBMED:11012190] [PUBMED:11376875] [PUBMED:8950973] [PUBMED:10517496] [PUBMED:8541543] [PUBMED:10736563] [PUBMED:12372629] [PUBMED:19262695] [PUBMED:9600081] [PUBMED:16317100] [PUBMED:10891439] [PUBMED:17693582] [PUBMED:16150872] [PUBMED:6313047] [PUBMED:14645506] [PUBMED:15693793] [PUBMED:19620302]
Endochondral Ossification [NCBI:198812] [WikiPathways:WP474] [PUBMED:17659995] [PUBMED:18374667]
Folate biosynthesis [NCBI:83018] [KEGG:hsa00790] [PUBMED:19675644] [PUBMED:16632608] [PUBMED:18092812] [PUBMED:12571226]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
TNF-alpha/NF-kB Signaling Pathway [NCBI:198884] [WikiPathways:WP231]