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Genes
KDM1A
Gene - KDM1A
full name
lysine demethylase 1A
synonyms
AOF2, BHC110, KDM1, LSD1, KDM1A, ENSG00000004487
HGNC
HGNC:29079
Entrez Gene
Gene:23028
ENSEMBL
ENSG00000004487
location
chr: 1
start: 23345937
stop: 23410184
strand: +
OMIM
OMIM:609132
: KDM1A
OMIM:616728
: Cleft palate, psychomotor retardation, and distinctive facial features
transcripts
NM_001009999.2
NM_015013.3
pathways
Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3
[NCBI:1269513]
[REACTOME:R-HSA-5625886]
[PUBMED:18066052]
[PUBMED:16079795]
[PUBMED:12514133]
Chromatin modifying enzymes
[NCBI:1270434]
[REACTOME:R-HSA-3247509]
Chromatin organization
[NCBI:1270433]
[REACTOME:R-HSA-4839726]
[PUBMED:21342762]
[PUBMED:15598472]
Coregulation of Androgen receptor activity
[NCBI:138085]
[Pathway Interaction Database:ar_pathway]
[PUBMED:16724108]
[PUBMED:16027218]
[PUBMED:11818503]
[PUBMED:17277772]
[PUBMED:11719514]
[PUBMED:15833840]
[PUBMED:16384856]
[PUBMED:14645241]
[PUBMED:12218053]
[PUBMED:11016951]
[PUBMED:12621049]
[PUBMED:15784617]
[PUBMED:16446156]
[PUBMED:17110431]
[PUBMED:16254014]
[PUBMED:17698582]
[PUBMED:15131260]
[PUBMED:16705743]
[PUBMED:11682623]
[PUBMED:17192406]
[PUBMED:15882980]
[PUBMED:10934038]
[PUBMED:12165860]
[PUBMED:11856738]
[PUBMED:16720717]
[PUBMED:9710597]
[PUBMED:14609956]
[PUBMED:17170703]
[PUBMED:10383460]
[PUBMED:14576337]
[PUBMED:12941811]
[PUBMED:14612401]
[PUBMED:17975004]
[PUBMED:12799378]
[PUBMED:15790678]
[PUBMED:8643607]
[PUBMED:11792840]
[PUBMED:16603237]
[PUBMED:16079795]
[PUBMED:16951154]
[PUBMED:15166229]
[PUBMED:17142810]
[PUBMED:12361945]
[PUBMED:11439351]
[PUBMED:15640154]
[PUBMED:17909037]
[PUBMED:15539430]
[PUBMED:11792709]
[PUBMED:11931767]
[PUBMED:10344732]
[PUBMED:10428808]
Factors involved in megakaryocyte development and platelet production
[NCBI:1269377]
[REACTOME:R-HSA-983231]
[PUBMED:16856888]
[PUBMED:17635743]
[PUBMED:17934486]
HDACs deacetylate histones
[NCBI:1270436]
[REACTOME:R-HSA-3214815]
[PUBMED:21872466]
[PUBMED:12429021]
HDMs demethylate histones
[NCBI:1270437]
[REACTOME:R-HSA-3214842]
[PUBMED:16261189]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
Notch signaling pathway
[NCBI:83062]
[KEGG:hsa04330]
[NCBI:169345]
[Pathway Interaction Database:notch_pathway]
[PUBMED:11459941]
[PUBMED:12682059]
[PUBMED:11825871]
[PUBMED:17658278]
[PUBMED:15998794]
[PUBMED:11101851]
[PUBMED:19686683]
[PUBMED:18490439]
[PUBMED:11150244]
[PUBMED:9694793]
[PUBMED:10206645]
[PUBMED:19704010]
[PUBMED:16137758]
[PUBMED:15288258]
[PUBMED:17392792]
[PUBMED:8749394]
[PUBMED:15965470]
[PUBMED:14566063]
[PUBMED:19567869]
[PUBMED:11585921]
[PUBMED:18676613]
[PUBMED:12913000]
[PUBMED:10593990]
[PUBMED:15274632]
[PUBMED:11777909]
[PUBMED:12015972]
[PUBMED:10028969]
[PUBMED:18043734]
[PUBMED:17658279]
[PUBMED:17575125]
[PUBMED:10958687]
[PUBMED:15300010]
[PUBMED:10882062]
[PUBMED:12374742]
[PUBMED:11782429]
[PUBMED:9653148]
[PUBMED:9315665]
[PUBMED:8643690]
[PUBMED:17114293]
[PUBMED:10837024]
[PUBMED:15067010]
[PUBMED:17296795]
[PUBMED:10940313]
[PUBMED:18628966]
[PUBMED:12826675]
[PUBMED:12681948]
[PUBMED:16492672]
[PUBMED:12551931]
[PUBMED:15082708]
[PUBMED:12464310]
[PUBMED:12794186]
[PUBMED:16107360]
[PUBMED:19726682]
[PUBMED:11486031]
[PUBMED:16287852]
[PUBMED:12297508]
[PUBMED:16061358]
[PUBMED:17107962]
[PUBMED:9244302]
[PUBMED:11425854]
[PUBMED:9620803]
[PUBMED:15272268]
[PUBMED:18417156]
[PUBMED:16000382]
[PUBMED:11896183]
[PUBMED:11604511]
[PUBMED:16847353]
[PUBMED:11432830]
[PUBMED:15652348]
[PUBMED:12417415]
[PUBMED:14567914]
[PUBMED:11006133]
[PUBMED:18077452]
[PUBMED:16144902]
[PUBMED:15288257]
[PUBMED:15585829]
[PUBMED:12370315]
[PUBMED:15288260]
[PUBMED:17434929]
[PUBMED:12814948]
[PUBMED:10882063]
[PUBMED:11518718]
Notch-mediated HES/HEY network
[NCBI:169347]
[Pathway Interaction Database:hes_heypathway]
[PUBMED:15546612]
[PUBMED:11038350]
[PUBMED:12065598]
[PUBMED:11741889]
[PUBMED:10851137]
[PUBMED:10205173]
[PUBMED:10747963]
[PUBMED:10913198]
[PUBMED:11101851]
[PUBMED:16201968]
[PUBMED:12488457]
[PUBMED:12370315]
[PUBMED:19116245]
[PUBMED:16025100]
[PUBMED:11486044]
[PUBMED:15607978]
[PUBMED:15467735]
[PUBMED:14739937]
[PUBMED:9694793]
[PUBMED:8749394]
[PUBMED:16782059]
[PUBMED:12972610]
[PUBMED:17392792]
[PUBMED:11334435]
[PUBMED:11486045]
[PUBMED:16753023]
[PUBMED:15485867]
[PUBMED:15866158]
[PUBMED:16199874]
[PUBMED:12374742]
[PUBMED:9570950]
[PUBMED:10964718]
[PUBMED:16682003]
[PUBMED:16287852]
[PUBMED:10692439]
[PUBMED:11095750]
[PUBMED:11287612]
[PUBMED:15314183]
[PUBMED:15156153]
[PUBMED:15684393]
[PUBMED:7566092]
[PUBMED:11604511]
[PUBMED:9819403]
[PUBMED:15563463]
[PUBMED:15870295]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases activate PKNs
[NCBI:1269512]
[REACTOME:R-HSA-5625740]
[PUBMED:21351730]
[PUBMED:21749319]
[PUBMED:10753910]
[PUBMED:18429822]
[PUBMED:9175763]
[PUBMED:12783890]
[PUBMED:14514689]
[PUBMED:10924361]
[PUBMED:7673228]
[PUBMED:10619026]
[PUBMED:10467162]
[PUBMED:11134534]
[PUBMED:9030526]
[PUBMED:9988689]
[PUBMED:19723632]
[PUBMED:24128008]
[PUBMED:18006505]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]