full name
RAN binding protein 2
synonyms
ANE1, IIAE3, NUP358, TRP1, TRP2, RANBP2, ENSG00000153201
HGNC
HGNC:9848
Entrez Gene
Gene:5903
ENSEMBL
ENSG00000153201
location
chr: 2
start: 109335902
stop: 109402267
strand: +
OMIM
OMIM:601181:
RANBP2
(Autosomal dominant inheritance)
OMIM:608033:
{Encephalopathy, acute, infection-induced, 3, susceptibility to}
transcripts
ENST00000283195.6
pathways
Antiviral mechanism by IFN-stimulated genes
[NCBI:1269316]
[REACTOME:R-HSA-1169410]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Cellular response to heat stress
[NCBI:1270421]
[REACTOME:R-HSA-3371556]
[PUBMED:8455624]
[PUBMED:8441385]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Export of Viral Ribonucleoproteins from Nucleus
[NCBI:1269121]
[REACTOME:R-HSA-168274]
[PUBMED:11118210]
[PUBMED:17081640]
[PUBMED:16806605]
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Gene Silencing by RNA
[NCBI:1269719]
[REACTOME:R-HSA-211000]
[PUBMED:15741316]
[PUBMED:25565029]
[PUBMED:19165215]
[PUBMED:21755468]
[PUBMED:16510870]
[PUBMED:19412884]
[PUBMED:17560368]
[PUBMED:19239886]
Glucose transport
[NCBI:1269921]
[REACTOME:R-HSA-70153]
[PUBMED:11780753]
HIV Infection
[NCBI:1269057]
[REACTOME:R-HSA-162906]
[PUBMED:16354571]
[PUBMED:9759480]
HIV Life Cycle
[NCBI:1269058]
[REACTOME:R-HSA-162587]
[PUBMED:9188609]
[PUBMED:9759480]
Hexose transport
[NCBI:1269920]
[REACTOME:R-HSA-189200]
[PUBMED:16186415]
[PUBMED:15546855]
Host Interactions of HIV factors
[NCBI:1269091]
[REACTOME:R-HSA-162909]
Host Interactions with Influenza Factors
[NCBI:1269130]
[REACTOME:R-HSA-168253]
ISG15 antiviral mechanism
[NCBI:1269317]
[REACTOME:R-HSA-1169408]
[PUBMED:20153823]
[PUBMED:12582176]
[PUBMED:16009940]
[PUBMED:20946978]
[PUBMED:15970528]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Infectious disease
[NCBI:1269056]
[REACTOME:R-HSA-5663205]
Influenza Infection
[NCBI:1269108]
[REACTOME:R-HSA-168254]
Influenza Life Cycle
[NCBI:1269109]
[REACTOME:R-HSA-168255]
Influenza Viral RNA Transcription and Replication
[NCBI:1269115]
[REACTOME:R-HSA-168273]
[PUBMED:2214032]
[PUBMED:6863242]
[PUBMED:6616622]
[PUBMED:6269803]
Interactions of Rev with host cellular proteins
[NCBI:1269095]
[REACTOME:R-HSA-177243]
[PUBMED:9837918]
Interactions of Vpr with host cellular proteins
[NCBI:1269092]
[REACTOME:R-HSA-176033]
[PUBMED:10620603]
[PUBMED:10958988]
[PUBMED:15817944]
[PUBMED:11531413]
[PUBMED:8041786]
[PUBMED:11815283]
[PUBMED:16354571]
[PUBMED:8709199]
[PUBMED:7474100]
[PUBMED:9436978]
[PUBMED:7474080]
[PUBMED:9582382]
[PUBMED:9188632]
[PUBMED:10684278]
Interferon Signaling
[NCBI:1269311]
[REACTOME:R-HSA-913531]
[PUBMED:18929502]
[PUBMED:15607020]
[PUBMED:15864272]
[PUBMED:14525967]
[PUBMED:19059436]
Late Phase of HIV Life Cycle
[NCBI:1269069]
[REACTOME:R-HSA-162599]
[PUBMED:2825027]
[PUBMED:10550206]
[PUBMED:10562489]
[PUBMED:15719065]
[PUBMED:15183343]
[PUBMED:3031512]
[PUBMED:9891806]
[PUBMED:2784194]
M Phase
[NCBI:1269810]
[REACTOME:R-HSA-68886]
Metabolism
[NCBI:1269956]
[REACTOME:R-HSA-1430728]
Metabolism of carbohydrates
[NCBI:1269957]
[REACTOME:R-HSA-71387]
Metabolism of non-coding RNA
[NCBI:1269731]
[REACTOME:R-HSA-194441]
Metabolism of proteins
[NCBI:1268677]
[REACTOME:R-HSA-392499]
Mitotic Anaphase
[NCBI:1269825]
[REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase
[NCBI:1269823]
[REACTOME:R-HSA-2555396]
Mitotic Prometaphase
[NCBI:1269820]
[REACTOME:R-HSA-68877]
Mitotic Prophase
[NCBI:1269811]
[REACTOME:R-HSA-68875]
NEP/NS2 Interacts with the Cellular Export Machinery
[NCBI:1269123]
[REACTOME:R-HSA-168333]
[PUBMED:17081640]
[PUBMED:11118210]
[PUBMED:12970177]
NS1 Mediated Effects on Host Pathways
[NCBI:1269131]
[REACTOME:R-HSA-168276]
Nuclear Envelope Breakdown
[NCBI:1269815]
[REACTOME:R-HSA-2980766]
[PUBMED:19234477]
Nuclear Pore Complex (NPC) Disassembly
[NCBI:1269817]
[REACTOME:R-HSA-3301854]
[PUBMED:18316408]
[PUBMED:21335236]
[PUBMED:12589057]
[PUBMED:19234477]
[PUBMED:22901806]
Nuclear import of Rev protein
[NCBI:1269096]
[REACTOME:R-HSA-180746]
Post-translational protein modification
[NCBI:1268701]
[REACTOME:R-HSA-597592]
Processing of Capped Intron-Containing Pre-mRNA
[NCBI:1269688]
[REACTOME:R-HSA-72203]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases Activate Formins
[NCBI:1269519]
[REACTOME:R-HSA-5663220]
[PUBMED:20233848]
[PUBMED:15507212]
[PUBMED:16292343]
[PUBMED:12906795]
[PUBMED:11779461]
[PUBMED:21397845]
[PUBMED:12577064]
[PUBMED:17198702]
[PUBMED:15006353]
[PUBMED:20101212]
[PUBMED:15944396]
[PUBMED:10678165]
[PUBMED:16943183]
[PUBMED:16439214]
[PUBMED:16472745]
[PUBMED:10958683]
[PUBMED:12732141]
[PUBMED:15085137]
[PUBMED:24914801]
[PUBMED:9497258]
[PUBMED:21576392]
[PUBMED:21868368]
RNA transport
[NCBI:177876]
[KEGG:hsa03013]
[PUBMED:10872469]
[PUBMED:17401408]
[PUBMED:20733056]
[PUBMED:11018020]
[PUBMED:15519698]
[PUBMED:16314458]
[PUBMED:15901496]
[PUBMED:9548260]
[PUBMED:18313922]
Regulation of Glucokinase by Glucokinase Regulatory Protein
[NCBI:1269922]
[REACTOME:R-HSA-170822]
[PUBMED:14627435]
[PUBMED:10601273]
Regulation of HSF1-mediated heat shock response
[NCBI:1270425]
[REACTOME:R-HSA-3371453]
[PUBMED:7623826]
Resolution of Sister Chromatid Cohesion
[NCBI:1269821]
[REACTOME:R-HSA-2500257]
[PUBMED:16541025]
[PUBMED:15339662]
[PUBMED:17112726]
[PUBMED:9649503]
[PUBMED:21111234]
[PUBMED:15737063]
[PUBMED:17113138]
[PUBMED:21987589]
[PUBMED:14730319]
[PUBMED:11509732]
[PUBMED:19696148]
[PUBMED:21878504]
[PUBMED:15723797]
Rev-mediated nuclear export of HIV RNA
[NCBI:1269085]
[REACTOME:R-HSA-165054]
[PUBMED:12932730]
[PUBMED:8805303]
[PUBMED:9791012]
SLC-mediated transmembrane transport
[NCBI:1269907]
[REACTOME:R-HSA-425407]
[PUBMED:14624363]
[PUBMED:19164095]
SUMO E3 ligases SUMOylate target proteins
[NCBI:1268743]
[REACTOME:R-HSA-3108232]
[PUBMED:20674646]
[PUBMED:17763827]
[PUBMED:19471022]
[PUBMED:23746258]
[PUBMED:24016193]
[PUBMED:23503365]
[PUBMED:21252943]
[PUBMED:17000644]
[PUBMED:24273646]
[PUBMED:22811915]
[PUBMED:21693764]
[PUBMED:23277067]
[PUBMED:21102611]
SUMOylation
[NCBI:1268738]
[REACTOME:R-HSA-2990846]
[PUBMED:21102611]
[PUBMED:20674646]
[PUBMED:23514139]
[PUBMED:19923268]
[PUBMED:20462400]
[PUBMED:17768054]
SUMOylation of DNA damage response and repair proteins
[NCBI:1268744]
[REACTOME:R-HSA-3108214]
[PUBMED:22018829]
[PUBMED:24926426]
[PUBMED:23122649]
[PUBMED:23781231]
[PUBMED:23416108]
[PUBMED:21486569]
[PUBMED:23746258]
[PUBMED:21896653]
[PUBMED:22357966]
[PUBMED:21664912]
SUMOylation of DNA replication proteins
[NCBI:1339113]
[REACTOME:R-HSA-4615885]
[PUBMED:22812528]
[PUBMED:17031663]
[PUBMED:22918591]
[PUBMED:22732495]
[PUBMED:16368276]
SUMOylation of RNA binding proteins
[NCBI:1339112]
[REACTOME:R-HSA-4570464]
[PUBMED:23979992]
[PUBMED:15161980]
Separation of Sister Chromatids
[NCBI:1269826]
[REACTOME:R-HSA-2467813]
[PUBMED:11081627]
[PUBMED:10411507]
[PUBMED:12070128]
[PUBMED:12194817]
[PUBMED:11509732]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Signaling events mediated by HDAC Class I
[NCBI:137997]
[Pathway Interaction Database:hdac_classi_pathway]
[PUBMED:9885572]
[PUBMED:14701748]
[PUBMED:10888618]
[PUBMED:12393750]
[PUBMED:9804427]
[PUBMED:9139820]
[PUBMED:12408818]
[PUBMED:16809764]
[PUBMED:12788099]
[PUBMED:11533489]
[PUBMED:15831498]
[PUBMED:15701600]
[PUBMED:11532945]
[PUBMED:12183469]
[PUBMED:16428440]
[PUBMED:9150134]
[PUBMED:12972430]
[PUBMED:11486036]
[PUBMED:15920470]
[PUBMED:9150135]
[PUBMED:9651585]
[PUBMED:11960997]
[PUBMED:9326634]
[PUBMED:11278251]
[PUBMED:14521922]
[PUBMED:9197243]
[PUBMED:9346952]
[PUBMED:16371367]
[PUBMED:10444591]
[PUBMED:15653507]
[PUBMED:15920471]
[PUBMED:11919195]
Signaling events mediated by HDAC Class II
[NCBI:138062]
[Pathway Interaction Database:hdac_classii_pathway]
[PUBMED:15916966]
[PUBMED:10869435]
[PUBMED:10898795]
[PUBMED:16051668]
[PUBMED:12032081]
[PUBMED:12606581]
[PUBMED:11804585]
[PUBMED:11466315]
[PUBMED:11567998]
[PUBMED:16767219]
[PUBMED:12024216]
[PUBMED:16166628]
[PUBMED:16221676]
[PUBMED:11948178]
[PUBMED:10220385]
[PUBMED:12663674]
[PUBMED:14668799]
[PUBMED:16236793]
Sumoylation by RanBP2 regulates transcriptional repression
[NCBI:138029]
[Pathway Interaction Database:ranbp2pathway]
[PUBMED:11960997]
[PUBMED:12393906]
[PUBMED:8978815]
[PUBMED:9456312]
[PUBMED:12032081]
[PUBMED:9019411]
[PUBMED:9427648]
[PUBMED:9108047]
[PUBMED:12393750]
[PUBMED:10892746]
[PUBMED:9323132]
[PUBMED:10454574]
Transcriptional regulation by small RNAs
[NCBI:1269723]
[REACTOME:R-HSA-5578749]
[PUBMED:19771207]
[PUBMED:18852463]
[PUBMED:25131816]
[PUBMED:22283730]
[PUBMED:22445173]
[PUBMED:24388755]
[PUBMED:15963934]
[PUBMED:24468964]
[PUBMED:22961379]
[PUBMED:22722852]
[PUBMED:21948593]
[PUBMED:22053081]
[PUBMED:15643423]
[PUBMED:16373483]
[PUBMED:24384674]
[PUBMED:23150874]
[PUBMED:20373265]
[PUBMED:22336708]
[PUBMED:16936726]
[PUBMED:24680896]
[PUBMED:23882114]
Transmembrane transport of small molecules
[NCBI:1269903]
[REACTOME:R-HSA-382551]
Transport of Mature Transcript to Cytoplasm
[NCBI:1269693]
[REACTOME:R-HSA-72202]
Transport of Mature mRNA Derived from an Intronless Transcript
[NCBI:1269698]
[REACTOME:R-HSA-159231]
Transport of Mature mRNA derived from an Intron-Containing Transcript
[NCBI:1269694]
[REACTOME:R-HSA-159236]
Transport of Mature mRNAs Derived from Intronless Transcripts
[NCBI:1269695]
[REACTOME:R-HSA-159234]
Transport of Ribonucleoproteins into the Host Nucleus
[NCBI:1269114]
[REACTOME:R-HSA-168271]
Transport of the SLBP Dependant Mature mRNA
[NCBI:1269696]
[REACTOME:R-HSA-159230]
Transport of the SLBP independent Mature mRNA
[NCBI:1269697]
[REACTOME:R-HSA-159227]
Viral Messenger RNA Synthesis
[NCBI:1269117]
[REACTOME:R-HSA-168325]
[PUBMED:16933365]
[PUBMED:16806605]
[PUBMED:15298169]
Vpr-mediated nuclear import of PICs
[NCBI:1269094]
[REACTOME:R-HSA-180910]
snRNP Assembly
[NCBI:1269732]
[REACTOME:R-HSA-191859]
[PUBMED:15130578]
tRNA processing
[NCBI:1309088]
[REACTOME:R-HSA-72306]
[PUBMED:24315934]
[PUBMED:24917879]
[PUBMED:7759547]
[PUBMED:24898039]
[PUBMED:26016801]
[PUBMED:24490730]
[PUBMED:20810645]
[PUBMED:21910628]
tRNA processing in the nucleus
[NCBI:1309089]
[REACTOME:R-HSA-6784531]
[PUBMED:12045094]
[PUBMED:20101632]
[PUBMED:20716516]
[PUBMED:20810645]
[PUBMED:21572561]
[PUBMED:16040803]
[PUBMED:16061803]
[PUBMED:22426497]
[PUBMED:25755220]
[PUBMED:16364630]
[PUBMED:24596576]
[PUBMED:15879697]
[PUBMED:24898039]
[PUBMED:11871657]
