full name
interleukin 1 receptor antagonist

synonyms
DIRA, ICIL-1RA, IL-1ra, IL-1ra3, IL-1RN, IL1F3, IL1RA, IRAP, MVCD4, IL1RN, ENSG00000136689

HGNC
HGNC:6000

Entrez Gene
Gene:3557

ENSEMBL
ENSG00000136689

location
chr: 2
start: 113868693
stop: 113891593
strand: +

OMIM
OMIM:147679: IL1RN (Autosomal recessive inheritance)
OMIM:612852: Interleukin 1 receptor antagonist deficiency
OMIM:137215: {Gastric cancer risk after H. pylori infection}
OMIM:612628: {Microvascular complications of diabetes 4}

transcripts
NM_173841.2
NM_173843.2
NM_000577.4
NM_173842.2

pathways
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
IL1-mediated signaling events [NCBI:137944] [Pathway Interaction Database:il1pathway] [PUBMED:10854325] [PUBMED:11287640] [PUBMED:10747026] [PUBMED:11960013] [PUBMED:12150927] [PUBMED:1837145] [PUBMED:17197697] [PUBMED:9374458] [PUBMED:12721283] [PUBMED:8035875] [PUBMED:9261174] [PUBMED:9734363] [PUBMED:11460167] [PUBMED:7878046] [PUBMED:10373529] [PUBMED:2530587] [PUBMED:12538665] [PUBMED:10882101] [PUBMED:9360994] [PUBMED:9062194] [PUBMED:12242293] [PUBMED:8837778] [PUBMED:9430229] [PUBMED:7775431]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Interleukin-1 signaling [NCBI:1269320] [REACTOME:R-HSA-446652] [PUBMED:19302047] [PUBMED:19022706]
Interleukin-10 signaling [NCBI:1470924] [REACTOME:R-HSA-6783783] [PUBMED:11244051]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]