full name
STEAP3 metalloreductase

synonyms
AHMIO2, dudlin-2, STMP3, TSAP6, STEAP3, ENSG00000115107

HGNC
HGNC:24592

Entrez Gene
Gene:55240

ENSEMBL
ENSG00000115107

location
chr: 2
start: 119981384
stop: 120023228
strand: +

OMIM
OMIM:609671: STEAP3 (Autosomal dominant inheritance)
OMIM:615234: ?Anemia, hypochromic microcytic, with iron overload 2

transcripts
NM_182915.2
NM_018234.2
NM_001008410.1

pathways
Direct p53 effectors [NCBI:137939] [Pathway Interaction Database:p53downstreampathway] [PUBMED:7479001] [PUBMED:19626115] [PUBMED:10692390] [PUBMED:15289308] [PUBMED:14688482] [PUBMED:16301995] [PUBMED:11850816] [PUBMED:12370809] [PUBMED:16260627] [PUBMED:15186775] [PUBMED:15580302] [PUBMED:10748162] [PUBMED:10919640] [PUBMED:19011621] [PUBMED:12438652] [PUBMED:11559530] [PUBMED:11641774] [PUBMED:11971958] [PUBMED:9659898] [PUBMED:9343394] [PUBMED:10716435] [PUBMED:17146433] [PUBMED:17719542] [PUBMED:17938176] [PUBMED:17409421] [PUBMED:11032029] [PUBMED:15781865] [PUBMED:11463392] [PUBMED:9736732] [PUBMED:17268548] [PUBMED:8570655] [PUBMED:18046411] [PUBMED:12944906] [PUBMED:16249378] [PUBMED:15273740] [PUBMED:15598651] [PUBMED:10618379] [PUBMED:15958553] [PUBMED:17189187] [PUBMED:17145718] [PUBMED:11988847] [PUBMED:8119988] [PUBMED:12089322] [PUBMED:16286009] [PUBMED:12890671] [PUBMED:12402042] [PUBMED:10618714] [PUBMED:14730312] [PUBMED:12857899] [PUBMED:14963330] [PUBMED:11278953] [PUBMED:11973653] [PUBMED:12692263] [PUBMED:10984493] [PUBMED:10640990] [PUBMED:11545734] [PUBMED:16151013] [PUBMED:12372430] [PUBMED:16651407] [PUBMED:9891062] [PUBMED:12606722] [PUBMED:12453409] [PUBMED:15377670] [PUBMED:12667443] [PUBMED:17707234] [PUBMED:9920903] [PUBMED:14992722] [PUBMED:15790310] [PUBMED:15831478] [PUBMED:11314010] [PUBMED:10329733] [PUBMED:17264218] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:11814693] [PUBMED:17554199] [PUBMED:18250150] [PUBMED:10518217] [PUBMED:10891498] [PUBMED:10973264] [PUBMED:15077116] [PUBMED:16230375] [PUBMED:18485870] [PUBMED:7796420] [PUBMED:15710382] [PUBMED:17409411] [PUBMED:8319905] [PUBMED:10684646] [PUBMED:7566179] [PUBMED:8887630] [PUBMED:11807984] [PUBMED:9841917] [PUBMED:12654245] [PUBMED:9023107] [PUBMED:15103385] [PUBMED:11684014] [PUBMED:17110336] [PUBMED:11278253] [PUBMED:14576823] [PUBMED:8418500] [PUBMED:11350971] [PUBMED:11840333] [PUBMED:7651818] [PUBMED:7651386] [PUBMED:15378026] [PUBMED:15607964] [PUBMED:11279192] [PUBMED:10777218] [PUBMED:15334053] [PUBMED:12138177] [PUBMED:9619826] [PUBMED:16278683] [PUBMED:17189186] [PUBMED:16140933] [PUBMED:10094469] [PUBMED:9926927] [PUBMED:17719541] [PUBMED:15735003] [PUBMED:12853982] [PUBMED:14707288] [PUBMED:10777207]
Ferroptosis [NCBI:1510435] [KEGG:hsa04216] [PUBMED:27314071] [PUBMED:28066232] [PUBMED:27048822] [PUBMED:27791175] [PUBMED:26725301] [PUBMED:27842067] [PUBMED:26775689] [PUBMED:27842066] [PUBMED:22632964] [PUBMED:26405158] [PUBMED:28082232] [PUBMED:26794443] [PUBMED:26436293] [PUBMED:27860262] [PUBMED:28129536] [PUBMED:26653790]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
Iron uptake and transport [NCBI:1269948] [REACTOME:R-HSA-917937] [PUBMED:20495089] [PUBMED:19381358] [PUBMED:18259769]
TP53 Regulates Transcription of Cell Death Genes [NCBI:1383066] [REACTOME:R-HSA-5633008] [PUBMED:20353938] [PUBMED:18676979] [PUBMED:11511362] [PUBMED:11919562] [PUBMED:10973264] [PUBMED:15797384] [PUBMED:17442733] [PUBMED:15607964] [PUBMED:11278253] [PUBMED:23059823] [PUBMED:19549844] [PUBMED:11684014] [PUBMED:7566179] [PUBMED:17349958] [PUBMED:24739573] [PUBMED:18719709] [PUBMED:17284521] [PUBMED:23703390] [PUBMED:10807576] [PUBMED:10733530] [PUBMED:12402042] [PUBMED:12851404] [PUBMED:14729977] [PUBMED:18431400] [PUBMED:15377670] [PUBMED:12089322] [PUBMED:15273740] [PUBMED:11382926] [PUBMED:12606722] [PUBMED:14623878] [PUBMED:15577913] [PUBMED:16230375] [PUBMED:26122615] [PUBMED:11559530] [PUBMED:11054413] [PUBMED:22766503] [PUBMED:11463392] [PUBMED:16249378] [PUBMED:9326928] [PUBMED:14614825] [PUBMED:19615968] [PUBMED:16140933] [PUBMED:7834749] [PUBMED:16135520] [PUBMED:15126337] [PUBMED:15580302] [PUBMED:15289308] [PUBMED:10777207] [PUBMED:23365256] [PUBMED:19040420] [PUBMED:15735003] [PUBMED:14688482]
TP53 Regulates Transcription of Genes Involved in Cytochrome C Release [NCBI:1383068] [REACTOME:R-HSA-6803204] [PUBMED:12606722] [PUBMED:18676979] [PUBMED:11511362] [PUBMED:11463392] [PUBMED:10807576] [PUBMED:12851404] [PUBMED:12402042] [PUBMED:15273740] [PUBMED:14729977] [PUBMED:15735003] [PUBMED:15126337] [PUBMED:23365256] [PUBMED:22766503] [PUBMED:11684014] [PUBMED:15607964] [PUBMED:7834749]
Transcriptional Regulation by TP53 [NCBI:1269654] [REACTOME:R-HSA-3700989] [PUBMED:26122615] [PUBMED:19410540]
Transferrin endocytosis and recycling [NCBI:1269949] [REACTOME:R-HSA-917977] [PUBMED:2874839]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
p53 signaling pathway [NCBI:83055] [KEGG:hsa04115] [PUBMED:16557269] [PUBMED:10714958] [PUBMED:12505356] [PUBMED:16915296] [PUBMED:16697662] [PUBMED:15116721] [PUBMED:11313928] [PUBMED:11747320] [PUBMED:17409411] [PUBMED:15838523]