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Genes
MCM6
Gene - MCM6
full name
minichromosome maintenance complex component 6
synonyms
MCG40308, Mis5, P105MCM, MCM6, ENSG00000076003
HGNC
HGNC:6949
Entrez Gene
Gene:4175
ENSEMBL
ENSG00000076003
location
chr: 2
start: 136597196
stop: 136634047
strand: -
OMIM
OMIM:601806
: MCM6
(Autosomal recessive inheritance)
OMIM:223100
: Lactase persistence/nonpersistence
transcripts
NM_005915.5
pathways
Activation of ATR in response to replication stress
[NCBI:1269757]
[REACTOME:R-HSA-176187]
[PUBMED:12791985]
Activation of the pre-replicative complex
[NCBI:1269773]
[REACTOME:R-HSA-68962]
[PUBMED:10402192]
[PUBMED:11779870]
[PUBMED:10801458]
[PUBMED:12169736]
[PUBMED:11323433]
[PUBMED:9038340]
[PUBMED:9765232]
[PUBMED:9829972]
[PUBMED:10970868]
[PUBMED:9353276]
[PUBMED:7502077]
[PUBMED:11459976]
[PUBMED:11395502]
Assembly of the pre-replicative complex
[NCBI:1269833]
[REACTOME:R-HSA-68867]
[PUBMED:11801723]
[PUBMED:9829972]
[PUBMED:9288745]
[PUBMED:9407030]
[PUBMED:9927482]
[PUBMED:9335335]
[PUBMED:11046155]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle Checkpoints
[NCBI:1269742]
[REACTOME:R-HSA-69620]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Cell cycle
[NCBI:83054]
[KEGG:hsa04110]
[PUBMED:7973727]
[PUBMED:17568790]
[PUBMED:9832503]
[PUBMED:16936746]
[PUBMED:9029154]
[PUBMED:12573239]
[PUBMED:19020303]
[PUBMED:9618481]
[PUBMED:12809600]
[PUBMED:8242749]
[PUBMED:10385618]
[PUBMED:17426725]
[PUBMED:17018296]
[PUBMED:16212951]
[PUBMED:12925736]
[PUBMED:11099028]
[PUBMED:15568976]
[PUBMED:15838516]
[PUBMED:15838523]
[PUBMED:15876871]
[PUBMED:7908906]
[PUBMED:9889196]
DNA Replication
[NCBI:1269875]
[REACTOME:R-HSA-69306]
[PUBMED:11257218]
[PUBMED:12045100]
[PUBMED:1536007]
[PUBMED:10966477]
[PUBMED:1579437]
[PUBMED:8223461]
DNA Replication Pre-Initiation
[NCBI:1269832]
[REACTOME:R-HSA-69002]
DNA replication
[NCBI:83039]
[KEGG:hsa03030]
[PUBMED:9759502]
[PUBMED:8087839]
DNA strand elongation
[NCBI:1269784]
[REACTOME:R-HSA-69190]
[PUBMED:9081985]
[PUBMED:1976634]
[PUBMED:7623835]
[PUBMED:1536007]
[PUBMED:8594377]
G1/S Transition
[NCBI:1269768]
[REACTOME:R-HSA-69206]
G2/M Checkpoints
[NCBI:1269753]
[REACTOME:R-HSA-69481]
M/G1 Transition
[NCBI:1269831]
[REACTOME:R-HSA-68874]
Mitotic G1-G1/S phases
[NCBI:1269764]
[REACTOME:R-HSA-453279]
Orc1 removal from chromatin
[NCBI:1269782]
[REACTOME:R-HSA-68949]
[PUBMED:11931757]
[PUBMED:11739726]
[PUBMED:11809796]
[PUBMED:1110244]
Regulation of DNA replication
[NCBI:1269794]
[REACTOME:R-HSA-69304]
Removal of licensing factors from origins
[NCBI:1269796]
[REACTOME:R-HSA-69300]
S Phase
[NCBI:1269777]
[REACTOME:R-HSA-69242]
Switching of origins to a post-replicative state
[NCBI:1269781]
[REACTOME:R-HSA-69052]
Synthesis of DNA
[NCBI:1269779]
[REACTOME:R-HSA-69239]
Unwinding of DNA
[NCBI:1269785]
[REACTOME:R-HSA-176974]
[PUBMED:10834843]
[PUBMED:15707891]