full name
glucagon

synonyms
GLP1, GLP2, GRPP, GCG, ENSG00000115263

HGNC
HGNC:4191

Entrez Gene
Gene:2641

ENSEMBL
ENSG00000115263

location
chr: 2
start: 162999379
stop: 163008914
strand: -

OMIM
OMIM:138030: GCG

transcripts
NM_002054.4

pathways
Class B/2 (Secretin family receptors) [NCBI:1269570] [REACTOME:R-HSA-373080] [PUBMED:11790261]
FOXA1 transcription factor network [NCBI:137979] [Pathway Interaction Database:hnf3apathway] [PUBMED:9427758] [PUBMED:16087863] [PUBMED:12750453] [PUBMED:12441652] [PUBMED:11763995] [PUBMED:8441395] [PUBMED:8164696] [PUBMED:2786140] [PUBMED:8071346] [PUBMED:8598458] [PUBMED:16331276] [PUBMED:16214823] [PUBMED:10049364] [PUBMED:15987773] [PUBMED:10073575] [PUBMED:8058060] [PUBMED:16980581] [PUBMED:9685261] [PUBMED:16009131]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
G alpha (s) signalling events [NCBI:1269575] [REACTOME:R-HSA-418555] [PUBMED:12036966]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Glucagon signaling in metabolic regulation [NCBI:1270108] [REACTOME:R-HSA-163359] [PUBMED:12626323]
Glucagon signaling pathway [NCBI:1144996] [KEGG:hsa04922] [PUBMED:20735177] [PUBMED:19912989] [PUBMED:21941300] [PUBMED:22249520] [PUBMED:12626323] [PUBMED:16601267] [PUBMED:18669612] [PUBMED:24393785] [PUBMED:21346730] [PUBMED:22550228] [PUBMED:16479585] [PUBMED:24692138] [PUBMED:22495310] [PUBMED:22796337] [PUBMED:22004992] [PUBMED:24238363] [PUBMED:22503562]
Glucagon-like Peptide-1 (GLP1) regulates insulin secretion [NCBI:1270107] [REACTOME:R-HSA-381676] [PUBMED:8830891] [PUBMED:15569269] [PUBMED:17306374] [PUBMED:9914469] [PUBMED:17900700] [PUBMED:11078440] [PUBMED:12475787] [PUBMED:11815463]
Glucagon-type ligand receptors [NCBI:1269572] [REACTOME:R-HSA-420092] [PUBMED:12615957]
Incretin synthesis, secretion, and inactivation [NCBI:1268750] [REACTOME:R-HSA-400508] [PUBMED:19074620] [PUBMED:17498508] [PUBMED:17263764]
Insulin secretion [NCBI:777534] [KEGG:hsa04911] [PUBMED:9715374] [PUBMED:10605628] [PUBMED:9914469] [PUBMED:17306374] [PUBMED:20055708] [PUBMED:15655710] [PUBMED:19817784] [PUBMED:19074620] [PUBMED:14693691] [PUBMED:17084085] [PUBMED:20551594] [PUBMED:19036624] [PUBMED:22970724] [PUBMED:20225132] [PUBMED:19817800] [PUBMED:22974438] [PUBMED:21934040] [PUBMED:15271645] [PUBMED:19660440] [PUBMED:11522660]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Peptide hormone metabolism [NCBI:1268746] [REACTOME:R-HSA-2980736] [PUBMED:2663045] [PUBMED:21805235]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:11078440] [PUBMED:16321791] [PUBMED:11815463] [PUBMED:16556766]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Synthesis, secretion, and deacylation of Ghrelin [NCBI:1268748] [REACTOME:R-HSA-422085] [PUBMED:19280057] [PUBMED:18396350]
Synthesis, secretion, and inactivation of Glucagon-like Peptide-1 (GLP-1) [NCBI:1268751] [REACTOME:R-HSA-381771] [PUBMED:11564718] [PUBMED:17928588] [PUBMED:1499644] [PUBMED:17263764] [PUBMED:19074620] [PUBMED:17498508]