full name
signal transducer and activator of transcription 4

synonyms
SLEB11, STAT4, ENSG00000138378

HGNC
HGNC:11365

Entrez Gene
Gene:6775

ENSEMBL
ENSG00000138378

location
chr: 2
start: 191894302
stop: 192037404
strand: -

OMIM
OMIM:600558: STAT4
OMIM:612253: {Systemic lupus erythematosus, susceptibility to, 11}

transcripts
NM_001243835.1
NM_003151.3

pathways
Downstream signaling in naive CD8+ T cells [NCBI:138018] [Pathway Interaction Database:cd8tcrdownstreampathway] [PUBMED:293720] [PUBMED:7935374] [PUBMED:12065418] [PUBMED:8566027] [PUBMED:12917261] [PUBMED:8394352] [PUBMED:8441422] [PUBMED:1386920] [PUBMED:8617294] [PUBMED:12732656] [PUBMED:7889942] [PUBMED:1737937] [PUBMED:1381507] [PUBMED:16210616] [PUBMED:11927626] [PUBMED:10477579] [PUBMED:10206983] [PUBMED:8376940] [PUBMED:9395475] [PUBMED:12972619] [PUBMED:8394845] [PUBMED:11485747] [PUBMED:15814665] [PUBMED:14645153] [PUBMED:2119889] [PUBMED:8208531] [PUBMED:10970869] [PUBMED:8612134] [PUBMED:8623163] [PUBMED:16237086] [PUBMED:16585578] [PUBMED:10544201] [PUBMED:8397339] [PUBMED:14605368] [PUBMED:12560487] [PUBMED:7982959]
Hepatitis B [NCBI:694606] [KEGG:hsa05161] [PUBMED:19854353] [PUBMED:11604508] [PUBMED:11325602] [PUBMED:18931690] [PUBMED:16891440] [PUBMED:17158882] [PUBMED:11099494] [PUBMED:9325306] [PUBMED:18024894] [PUBMED:11483993] [PUBMED:15107488] [PUBMED:11278872] [PUBMED:21647825] [PUBMED:11287574] [PUBMED:18481805] [PUBMED:17188775] [PUBMED:19784739] [PUBMED:19263472] [PUBMED:16203685] [PUBMED:18605975] [PUBMED:10454581] [PUBMED:22504921] [PUBMED:21334391] [PUBMED:20657822] [PUBMED:18046710] [PUBMED:9843511] [PUBMED:15542625] [PUBMED:21618535] [PUBMED:15132991] [PUBMED:15173177] [PUBMED:12771941] [PUBMED:21994545] [PUBMED:8764004] [PUBMED:16459163] [PUBMED:9738022] [PUBMED:11821950] [PUBMED:12839924]
IL12 signaling mediated by STAT4 [NCBI:137936] [Pathway Interaction Database:il12_stat4pathway] [PUBMED:2504877] [PUBMED:7722452] [PUBMED:16365415] [PUBMED:9558063] [PUBMED:8700209] [PUBMED:9325300] [PUBMED:12213961] [PUBMED:10037767] [PUBMED:7737303] [PUBMED:10358173] [PUBMED:16641133] [PUBMED:12372421] [PUBMED:10946290] [PUBMED:11046021] [PUBMED:14660657] [PUBMED:15728489] [PUBMED:10097133] [PUBMED:11207258] [PUBMED:11801649] [PUBMED:11786644] [PUBMED:10229825] [PUBMED:11466347] [PUBMED:12716907] [PUBMED:8700208] [PUBMED:15522880]
IL12-mediated signaling events [NCBI:137922] [Pathway Interaction Database:il12_2pathway] [PUBMED:12874225] [PUBMED:12221108] [PUBMED:16380506] [PUBMED:9768751] [PUBMED:17114419] [PUBMED:10358173] [PUBMED:9890938] [PUBMED:12213961] [PUBMED:11120802] [PUBMED:9202126] [PUBMED:16641133] [PUBMED:10198225] [PUBMED:16763563] [PUBMED:15728489] [PUBMED:8103068] [PUBMED:10903740] [PUBMED:10201984] [PUBMED:7638186] [PUBMED:11894097] [PUBMED:16220539] [PUBMED:10961885] [PUBMED:7594594] [PUBMED:17110450] [PUBMED:9582275] [PUBMED:10320373] [PUBMED:7528775] [PUBMED:11207258] [PUBMED:9038232] [PUBMED:15522880] [PUBMED:11175814] [PUBMED:9531298] [PUBMED:7722452] [PUBMED:8943050] [PUBMED:7553885] [PUBMED:9454765]
IL23-mediated signaling events [NCBI:138000] [Pathway Interaction Database:il23pathway] [PUBMED:16200068] [PUBMED:12023338] [PUBMED:17030949] [PUBMED:16670770] [PUBMED:17074928] [PUBMED:15583831] [PUBMED:16919486] [PUBMED:12417590] [PUBMED:16622035] [PUBMED:16698929] [PUBMED:14978083] [PUBMED:12610626] [PUBMED:15308705] [PUBMED:16200070] [PUBMED:15657292] [PUBMED:16648837] [PUBMED:11114383] [PUBMED:12023369] [PUBMED:9038232]
IL27-mediated signaling events [NCBI:137929] [Pathway Interaction Database:il27pathway] [PUBMED:11672539] [PUBMED:16365415] [PUBMED:16906167] [PUBMED:15356135] [PUBMED:14657353] [PUBMED:15944269] [PUBMED:14764690] [PUBMED:14614852] [PUBMED:15308705] [PUBMED:15004160] [PUBMED:12734330] [PUBMED:11057672] [PUBMED:15494513] [PUBMED:14614853] [PUBMED:12121660] [PUBMED:16906166] [PUBMED:15749890]
Inflammatory bowel disease (IBD) [NCBI:842771] [KEGG:hsa05321] [PUBMED:17499605] [PUBMED:12006974] [PUBMED:18053739] [PUBMED:20134493] [PUBMED:10898785] [PUBMED:18563156] [PUBMED:23176791] [PUBMED:18200661] [PUBMED:12797537] [PUBMED:21487504] [PUBMED:19381306] [PUBMED:21681604] [PUBMED:19322214] [PUBMED:16493424] [PUBMED:18242222] [PUBMED:12042806] [PUBMED:9759857]
Jak-STAT signaling pathway [NCBI:83077] [KEGG:hsa04630] [PUBMED:21034406] [PUBMED:22339650] [PUBMED:16204702] [PUBMED:25587654] [PUBMED:24069565] [PUBMED:22383755] [PUBMED:24606160] [PUBMED:10851053] [PUBMED:23735217] [PUBMED:25217450] [PUBMED:21372217]
Th1 and Th2 cell differentiation [NCBI:1458885] [KEGG:hsa04658] [PUBMED:15819694] [PUBMED:12171942] [PUBMED:19165228] [PUBMED:23336087] [PUBMED:26044597] [PUBMED:19151746] [PUBMED:19362457] [PUBMED:22044277] [PUBMED:11752608] [PUBMED:23405903] [PUBMED:19375293] [PUBMED:24113868] [PUBMED:19151747] [PUBMED:23624818] [PUBMED:22566933] [PUBMED:11121747] [PUBMED:20969597] [PUBMED:20065998]