full name
phosphoinositide kinase, FYVE-type zinc finger containing

synonyms
CFD, FAB1, PIP5K, PIP5K3, ZFYVE29, PIKFYVE, ENSG00000115020

HGNC
HGNC:23785

Entrez Gene
Gene:200576

ENSEMBL
ENSG00000115020

location
chr: 2
start: 209130990
stop: 209223475
strand: +

OMIM
OMIM:609414: PIKFYVE (Autosomal dominant inheritance)
OMIM:121850: Corneal fleck dystrophy

transcripts
NM_015040.3
NM_001178000.1
NM_152671.3

pathways
3-phosphoinositide biosynthesis [NCBI:545314] [BIOCYC:HUMAN_PWY-6352] [PUBMED:9632630] [PUBMED:7798235] [PUBMED:2553693] [PUBMED:8086005] [PUBMED:9247130]
Inositol phosphate metabolism [NCBI:82987] [KEGG:hsa00562] [NCBI:1269988] [REACTOME:R-HSA-1483249] [PUBMED:17943301] [PUBMED:18310071] [PUBMED:20414202] [PUBMED:11331907] [PUBMED:20359876] [PUBMED:14993306] [PUBMED:16781889]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
PI Metabolism [NCBI:1270073] [REACTOME:R-HSA-1483255] [PUBMED:17035995] [PUBMED:18216768] [PUBMED:17330069] [PUBMED:15170460] [PUBMED:16828287] [PUBMED:18726176] [PUBMED:20861159] [PUBMED:19196647] [PUBMED:20043944] [PUBMED:20192774] [PUBMED:18784754] [PUBMED:20559318] [PUBMED:18216767] [PUBMED:17605038] [PUBMED:15269334]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Phosphatidylinositol signaling system [NCBI:83052] [KEGG:hsa04070] [PUBMED:19439500] [PUBMED:19580826]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Regulation of actin cytoskeleton [NCBI:83089] [KEGG:hsa04810] [PUBMED:11152757] [PUBMED:11082272] [PUBMED:10574699] [PUBMED:11082269] [PUBMED:14657486] [PUBMED:14744429] [PUBMED:12700767]
Synthesis of PIPs at the Golgi membrane [NCBI:1270075] [REACTOME:R-HSA-1660514] [PUBMED:11279162] [PUBMED:17556371] [PUBMED:10766823] [PUBMED:10559940] [PUBMED:10805725] [PUBMED:14527956] [PUBMED:18950639]
Synthesis of PIPs at the early endosome membrane [NCBI:1270079] [REACTOME:R-HSA-1660516] [PUBMED:18950639] [PUBMED:11733541] [PUBMED:18524850] [PUBMED:17556371] [PUBMED:17651088] [PUBMED:10805725]
Synthesis of PIPs at the late endosome membrane [NCBI:1270082] [REACTOME:R-HSA-1660517] [PUBMED:18524850] [PUBMED:17556371] [PUBMED:17651088] [PUBMED:10805725] [PUBMED:11733541] [PUBMED:18950639]
superpathway of inositol phosphate compounds [NCBI:547492] [BIOCYC:HUMAN_PWY-6371]