full name
fibronectin 1
synonyms
CIG, ED-B, FINC, FN, FNZ, GFND, GFND2, LETS, MSF, FN1, ENSG00000115414
HGNC
HGNC:3778
Entrez Gene
Gene:2335
ENSEMBL
ENSG00000115414
location
chr: 2
start: 216225177
stop: 216300890
strand: -
OMIM
OMIM:135600:
FN1
(Autosomal dominant inheritance)
OMIM:601894:
Glomerulopathy with fibronectin deposits 2
OMIM:614101:
Plasma fibronectin deficiency
transcripts
ENST00000357867.4
ENST00000356005.4
ENST00000336916.4
ENST00000354785.4
NM_054034.2
pathways
AGE-RAGE signaling pathway in diabetic complications
[NCBI:1319988]
[KEGG:hsa04933]
[PUBMED:23776698]
[PUBMED:15569303]
[PUBMED:16894049]
[PUBMED:18323529]
[PUBMED:11375353]
[PUBMED:21111800]
[PUBMED:19404313]
[PUBMED:20470857]
[PUBMED:17005604]
[PUBMED:23961320]
[PUBMED:21261520]
[PUBMED:11180401]
[PUBMED:18922799]
[PUBMED:21680901]
[PUBMED:11684565]
[PUBMED:21590515]
[PUBMED:12709399]
[PUBMED:20300563]
[PUBMED:21440603]
[PUBMED:22558488]
ARMS-mediated activation
[NCBI:1269471]
[REACTOME:R-HSA-170984]
[PUBMED:9069267]
Amoebiasis
[NCBI:167324]
[KEGG:hsa05146]
[PUBMED:9832261]
[PUBMED:16380324]
[PUBMED:14700586]
[PUBMED:18725798]
[PUBMED:12142490]
[PUBMED:10637584]
[PUBMED:20145703]
[PUBMED:11378035]
[PUBMED:12160867]
[PUBMED:15813717]
[PUBMED:19207103]
[PUBMED:12660071]
[PUBMED:20303955]
[PUBMED:11352795]
[PUBMED:14502002]
[PUBMED:10756002]
[PUBMED:17702556]
[PUBMED:17576362]
Angiopoietin receptor Tie2-mediated signaling
[NCBI:137917]
[Pathway Interaction Database:angiopoietinreceptor_pathway]
[PUBMED:9204896]
[PUBMED:12609966]
[PUBMED:14726409]
[PUBMED:11157678]
[PUBMED:10347092]
[PUBMED:11967990]
[PUBMED:15162796]
[PUBMED:11289054]
[PUBMED:12759249]
[PUBMED:10051567]
[PUBMED:12824293]
[PUBMED:16895971]
[PUBMED:10807867]
[PUBMED:12933576]
[PUBMED:11513602]
[PUBMED:12074640]
[PUBMED:8980223]
[PUBMED:14665640]
[PUBMED:15132996]
[PUBMED:10944458]
[PUBMED:11230987]
[PUBMED:15242771]
[PUBMED:10585289]
[PUBMED:16061664]
[PUBMED:10376602]
[PUBMED:15350545]
[PUBMED:9632797]
[PUBMED:10625301]
[PUBMED:9926914]
[PUBMED:17189382]
[PUBMED:11139469]
[PUBMED:11689432]
[PUBMED:11416142]
[PUBMED:11166279]
[PUBMED:15284220]
[PUBMED:15985432]
[PUBMED:16049136]
[PUBMED:16157706]
[PUBMED:10521483]
[PUBMED:12816861]
[PUBMED:9478921]
[PUBMED:10376603]
[PUBMED:15769741]
[PUBMED:12890486]
[PUBMED:14749497]
[PUBMED:7561682]
[PUBMED:11801735]
[PUBMED:12665569]
[PUBMED:12117724]
[PUBMED:9764820]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Bacterial invasion of epithelial cells
[NCBI:149807]
[KEGG:hsa05100]
[PUBMED:17298394]
[PUBMED:16406780]
[PUBMED:19185531]
[PUBMED:19157959]
[PUBMED:17719540]
[PUBMED:19296488]
Cell surface interactions at the vascular wall
[NCBI:1269373]
[REACTOME:R-HSA-202733]
[PUBMED:17525755]
[PUBMED:11282294]
[PUBMED:10798271]
[PUBMED:8578462]
[PUBMED:14615387]
[PUBMED:16115029]
Cytokine Signaling in Immune system
[NCBI:1269310]
[REACTOME:R-HSA-1280215]
[PUBMED:12613569]
DAP12 interactions
[NCBI:1269283]
[REACTOME:R-HSA-2172127]
[PUBMED:19120482]
[PUBMED:17220916]
[PUBMED:9490415]
[PUBMED:18192027]
[PUBMED:15884055]
DAP12 signaling
[NCBI:1269284]
[REACTOME:R-HSA-2424491]
[PUBMED:15884055]
[PUBMED:17110943]
[PUBMED:17220916]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases of signal transduction
[NCBI:1268855]
[REACTOME:R-HSA-5663202]
[PUBMED:12509752]
Downstream signal transduction
[NCBI:1269479]
[REACTOME:R-HSA-186763]
[PUBMED:10508235]
[PUBMED:9739761]
ECM-receptor interaction
[NCBI:83068]
[KEGG:hsa04512]
[PUBMED:7698997]
[PUBMED:15381249]
[PUBMED:12796473]
[PUBMED:11331578]
[PUBMED:15036264]
[PUBMED:12125070]
[PUBMED:12736199]
[PUBMED:15229478]
[PUBMED:11572082]
[PUBMED:10617638]
[PUBMED:12845610]
[PUBMED:12921709]
Extracellular matrix organization
[NCBI:1270244]
[REACTOME:R-HSA-1474244]
[PUBMED:21123617]
[PUBMED:21917992]
[PUBMED:12845610]
FCERI mediated MAPK activation
[NCBI:1269299]
[REACTOME:R-HSA-2871796]
[PUBMED:19290926]
[PUBMED:19909365]
[PUBMED:17122878]
Fc epsilon receptor (FCERI) signaling
[NCBI:1269298]
[REACTOME:R-HSA-2454202]
[PUBMED:15099567]
[PUBMED:21799019]
Fibronectin matrix formation
[NCBI:1270250]
[REACTOME:R-HSA-1566977]
[PUBMED:20690820]
Focal adhesion
[NCBI:83067]
[KEGG:hsa04510]
[PUBMED:10698680]
[PUBMED:15459662]
[PUBMED:14756624]
[PUBMED:11573199]
[PUBMED:12640026]
[PUBMED:15179030]
[PUBMED:15108811]
[PUBMED:15053919]
[PUBMED:11082269]
[PUBMED:15034601]
[PUBMED:12235283]
[PUBMED:14519391]
[PUBMED:11146675]
[PUBMED:11229600]
[PUBMED:15688067]
[PUBMED:14744429]
[PUBMED:11882383]
Frs2-mediated activation
[NCBI:1269470]
[REACTOME:R-HSA-170968]
[PUBMED:9069267]
GRB2 events in EGFR signaling
[NCBI:1269382]
[REACTOME:R-HSA-179812]
[PUBMED:11706405]
[PUBMED:11498013]
GRB2:SOS provides linkage to MAPK signaling for Integrins
[NCBI:1269360]
[REACTOME:R-HSA-354194]
[PUBMED:9566877]
[PUBMED:7997267]
[PUBMED:12005431]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
Hemostasis
[NCBI:1269340]
[REACTOME:R-HSA-109582]
IGF1R signaling cascade
[NCBI:1269618]
[REACTOME:R-HSA-2428924]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
IRS-mediated signalling
[NCBI:1269431]
[REACTOME:R-HSA-112399]
IRS-related events triggered by IGF1R
[NCBI:1269620]
[REACTOME:R-HSA-2428928]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22649417]
[PUBMED:18927274]
[PUBMED:21042815]
[PUBMED:20098959]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Insulin receptor signalling cascade
[NCBI:1269429]
[REACTOME:R-HSA-74751]
[PUBMED:9677303]
[PUBMED:11282018]
Integrin alphaIIb beta3 signaling
[NCBI:1269359]
[REACTOME:R-HSA-354192]
[PUBMED:10605720]
[PUBMED:14754902]
[PUBMED:17624957]
[PUBMED:16102042]
[PUBMED:15205259]
[PUBMED:10508650]
Integrin cell surface interactions
[NCBI:1270260]
[REACTOME:R-HSA-216083]
[PUBMED:10215583]
[PUBMED:15147720]
[PUBMED:12231361]
[PUBMED:8866399]
[PUBMED:19273203]
Integrins in angiogenesis
[NCBI:137999]
[Pathway Interaction Database:avb3_integrin_pathway]
[PUBMED:10837460]
[PUBMED:9182576]
[PUBMED:12642872]
[PUBMED:15711558]
[PUBMED:10037797]
[PUBMED:10196194]
[PUBMED:11877390]
[PUBMED:16418218]
[PUBMED:16600665]
[PUBMED:16982628]
[PUBMED:15479743]
[PUBMED:16720645]
[PUBMED:11684710]
[PUBMED:10821695]
[PUBMED:12237112]
[PUBMED:12750158]
[PUBMED:11551924]
[PUBMED:8794870]
[PUBMED:10022831]
[PUBMED:15187087]
[PUBMED:16195423]
[PUBMED:16760434]
[PUBMED:12682293]
[PUBMED:9420328]
[PUBMED:15247219]
[PUBMED:9490736]
[PUBMED:11313365]
Interleukin receptor SHC signaling
[NCBI:1269322]
[REACTOME:R-HSA-912526]
[PUBMED:8294403]
Interleukin-2 signaling
[NCBI:1269321]
[REACTOME:R-HSA-451927]
[PUBMED:17936914]
[PUBMED:18817510]
[PUBMED:19543225]
[PUBMED:18062768]
Interleukin-3, 5 and GM-CSF signaling
[NCBI:1269323]
[REACTOME:R-HSA-512988]
[PUBMED:10450743]
[PUBMED:9766809]
Interleukin-4 and 13 signaling
[NCBI:1470923]
[REACTOME:R-HSA-6785807]
[PUBMED:12704343]
[PUBMED:10358772]
MAP2K and MAPK activation
[NCBI:1269287]
[REACTOME:R-HSA-5674135]
[PUBMED:21779496]
[PUBMED:20674547]
[PUBMED:22569528]
[PUBMED:22177953]
[PUBMED:19091303]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK1/MAPK3 signaling
[NCBI:1269502]
[REACTOME:R-HSA-5684996]
[PUBMED:25378393]
[PUBMED:18199641]
[PUBMED:17496909]
[PUBMED:21779496]
[PUBMED:15520807]
[PUBMED:16393692]
[PUBMED:19520853]
[PUBMED:17496910]
[PUBMED:22569528]
NCAM signaling for neurite out-growth
[NCBI:1270312]
[REACTOME:R-HSA-375165]
[PUBMED:18760361]
[PUBMED:12587671]
[PUBMED:15662836]
[PUBMED:17975827]
[PUBMED:15153429]
[PUBMED:12700044]
NGF signalling via TRKA from the plasma membrane
[NCBI:1269460]
[REACTOME:R-HSA-187037]
[PUBMED:11520933]
[PUBMED:12676795]
[PUBMED:10851172]
[PUBMED:10579918]
Oncogenic MAPK signaling
[NCBI:1457781]
[REACTOME:R-HSA-6802957]
[PUBMED:25907612]
[PUBMED:24651010]
[PUBMED:24202393]
[PUBMED:25435214]
[PUBMED:21993244]
[PUBMED:24814062]
[PUBMED:22589270]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Paradoxical activation of RAF signaling by kinase inactive BRAF
[NCBI:1457785]
[REACTOME:R-HSA-6802955]
[PUBMED:25435214]
[PUBMED:20674547]
[PUBMED:24957944]
[PUBMED:23352452]
[PUBMED:20130576]
[PUBMED:23680146]
[PUBMED:16364920]
[PUBMED:25907612]
[PUBMED:15035987]
[PUBMED:20179705]
[PUBMED:19727074]
[PUBMED:20141835]
[PUBMED:22510884]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Platelet Aggregation (Plug Formation)
[NCBI:1269358]
[REACTOME:R-HSA-76009]
[PUBMED:18174460]
[PUBMED:17585075]
Platelet activation, signaling and aggregation
[NCBI:1269350]
[REACTOME:R-HSA-76002]
[PUBMED:16543958]
[PUBMED:8704248]
[PUBMED:2018971]
[PUBMED:1672265]
[PUBMED:17059469]
[PUBMED:12681240]
[PUBMED:12411949]
[PUBMED:11511514]
Platelet degranulation
[NCBI:1269367]
[REACTOME:R-HSA-114608]
[PUBMED:14630798]
Prolonged ERK activation events
[NCBI:1269469]
[REACTOME:R-HSA-169893]
[PUBMED:12765839]
[PUBMED:9069267]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
RAF/MAP kinase cascade
[NCBI:1269285]
[REACTOME:R-HSA-5673001]
[PUBMED:21167873]
[PUBMED:24937142]
[PUBMED:20674547]
[PUBMED:17496910]
[PUBMED:22177953]
[PUBMED:17496919]
[PUBMED:22569528]
[PUBMED:22535895]
[PUBMED:12068308]
[PUBMED:17496923]
[PUBMED:19091303]
[PUBMED:21372320]
[PUBMED:21388974]
[PUBMED:15520807]
RET signaling
[NCBI:1427866]
[REACTOME:R-HSA-8853659]
[PUBMED:15013219]
[PUBMED:17036197]
Regulation of actin cytoskeleton
[NCBI:83089]
[KEGG:hsa04810]
[PUBMED:11152757]
[PUBMED:11082272]
[PUBMED:10574699]
[PUBMED:11082269]
[PUBMED:14657486]
[PUBMED:14744429]
[PUBMED:12700767]
Response to elevated platelet cytosolic Ca2+
[NCBI:1269365]
[REACTOME:R-HSA-76005]
[PUBMED:8424766]
SHC1 events in EGFR signaling
[NCBI:1269383]
[REACTOME:R-HSA-180336]
[PUBMED:11498013]
[PUBMED:8755247]
SOS-mediated signalling
[NCBI:1269440]
[REACTOME:R-HSA-112412]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by BRAF and RAF fusions
[NCBI:1457786]
[REACTOME:R-HSA-6802952]
[PUBMED:18974108]
[PUBMED:24135138]
[PUBMED:22745804]
[PUBMED:25907612]
[PUBMED:20526349]
[PUBMED:15630448]
[PUBMED:25204415]
[PUBMED:24345920]
[PUBMED:21424530]
[PUBMED:23583981]
Signaling by EGFR
[NCBI:1269380]
[REACTOME:R-HSA-177929]
[PUBMED:10459005]
[PUBMED:10404636]
[PUBMED:12297041]
[PUBMED:15142631]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Insulin receptor
[NCBI:1269428]
[REACTOME:R-HSA-74752]
[PUBMED:8276779]
Signaling by Interleukins
[NCBI:1269318]
[REACTOME:R-HSA-449147]
[PUBMED:19302047]
[PUBMED:12445398]
Signaling by Leptin
[NCBI:1269632]
[REACTOME:R-HSA-2586552]
[PUBMED:22211890]
[PUBMED:23562747]
[PUBMED:20600241]
[PUBMED:21622208]
[PUBMED:23579596]
[PUBMED:22458591]
[PUBMED:21489811]
[PUBMED:19724019]
[PUBMED:21331644]
[PUBMED:22448029]
[PUBMED:21147620]
[PUBMED:20198122]
[PUBMED:21677426]
[PUBMED:20029269]
[PUBMED:22249808]
[PUBMED:22991412]
[PUBMED:21527729]
[PUBMED:17937601]
[PUBMED:20553370]
[PUBMED:21713385]
[PUBMED:23565489]
[PUBMED:22289780]
Signaling by PDGF
[NCBI:1269478]
[REACTOME:R-HSA-186797]
[PUBMED:15207811]
[PUBMED:10508235]
[PUBMED:9739761]
Signaling by RAS mutants
[NCBI:1457782]
[REACTOME:R-HSA-6802949]
[PUBMED:21993244]
[PUBMED:22589270]
[PUBMED:24651010]
Signaling by SCF-KIT
[NCBI:1269487]
[REACTOME:R-HSA-1433557]
[PUBMED:17350321]
[PUBMED:16483568]
[PUBMED:7688988]
[PUBMED:19540337]
[PUBMED:16475976]
[PUBMED:15526160]
Signaling by Type 1 Insulin-like Growth Factor 1 Receptor (IGF1R)
[NCBI:1269617]
[REACTOME:R-HSA-2404192]
[PUBMED:21042815]
[PUBMED:18927274]
[PUBMED:20098959]
[PUBMED:17598937]
[PUBMED:20975071]
[PUBMED:22044904]
[PUBMED:22649417]
Signaling by VEGF
[NCBI:1269480]
[REACTOME:R-HSA-194138]
[PUBMED:15585754]
[PUBMED:13678960]
[PUBMED:16336962]
[PUBMED:16835467]
Signaling by high-kinase activity BRAF mutants
[NCBI:1457783]
[REACTOME:R-HSA-6802948]
[PUBMED:16702958]
[PUBMED:21190184]
[PUBMED:23352452]
[PUBMED:16364920]
[PUBMED:22113612]
[PUBMED:12068308]
[PUBMED:15035987]
[PUBMED:22510884]
[PUBMED:25435214]
[PUBMED:24202393]
Signaling by moderate kinase activity BRAF mutants
[NCBI:1457784]
[REACTOME:R-HSA-6802946]
[PUBMED:25907612]
[PUBMED:15035987]
[PUBMED:24202393]
[PUBMED:22510884]
[PUBMED:25355519]
[PUBMED:23352452]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
Signalling to ERKs
[NCBI:1269464]
[REACTOME:R-HSA-187687]
[PUBMED:10508738]
Signalling to RAS
[NCBI:1269465]
[REACTOME:R-HSA-167044]
[PUBMED:11520933]
Signalling to p38 via RIT and RIN
[NCBI:1269468]
[REACTOME:R-HSA-187706]
[PUBMED:10712923]
Small cell lung cancer
[NCBI:83118]
[KEGG:hsa05222]
[PUBMED:12711111]
[PUBMED:11463388]
[PUBMED:12741677]
[PUBMED:11905738]
[PUBMED:11807782]
[PUBMED:12379883]
[PUBMED:12243753]
[PUBMED:12616528]
[PUBMED:11720739]
[PUBMED:15109562]
[PUBMED:12407699]
[PUBMED:10944551]
[PUBMED:16112428]
[PUBMED:11559746]
[PUBMED:16064138]
[PUBMED:11902573]
Syndecan-2-mediated signaling events
[NCBI:138031]
[Pathway Interaction Database:syndecan_2_pathway]
[PUBMED:17623663]
[PUBMED:11373281]
[PUBMED:16357320]
[PUBMED:12507425]
[PUBMED:16945929]
[PUBMED:14976204]
[PUBMED:10772816]
[PUBMED:10843988]
[PUBMED:8528141]
[PUBMED:15936998]
[PUBMED:10734053]
[PUBMED:11179419]
[PUBMED:9660868]
[PUBMED:16198615]
[PUBMED:9660869]
[PUBMED:15752734]
[PUBMED:10446183]
[PUBMED:11580899]
[PUBMED:17548511]
[PUBMED:11931647]
[PUBMED:16139226]
[PUBMED:16008343]
[PUBMED:14527339]
[PUBMED:16997272]
[PUBMED:10639336]
[PUBMED:16440330]
[PUBMED:11018053]
[PUBMED:10704377]
[PUBMED:9244383]
[PUBMED:12860416]
Syndecan-4-mediated signaling events
[NCBI:138064]
[Pathway Interaction Database:syndecan_4_pathway]
[PUBMED:16604063]
[PUBMED:8621465]
[PUBMED:17485492]
[PUBMED:10633082]
[PUBMED:14580209]
[PUBMED:14670076]
[PUBMED:16357320]
[PUBMED:11373281]
[PUBMED:11805099]
[PUBMED:12087088]
[PUBMED:16087677]
[PUBMED:8589452]
[PUBMED:17901052]
[PUBMED:12571249]
[PUBMED:16310216]
[PUBMED:15694365]
[PUBMED:17130131]
[PUBMED:17879962]
[PUBMED:8609172]
[PUBMED:12493766]
[PUBMED:10640397]
[PUBMED:15819887]
[PUBMED:10625452]
[PUBMED:9582338]
[PUBMED:14637022]
[PUBMED:12509413]
[PUBMED:16141413]
[PUBMED:10734086]
[PUBMED:10911369]
VEGFA-VEGFR2 Pathway
[NCBI:1269483]
[REACTOME:R-HSA-4420097]
[PUBMED:17344076]
[PUBMED:16633338]
[PUBMED:19230644]
[PUBMED:13678960]
VEGFR2 mediated cell proliferation
[NCBI:1269485]
[REACTOME:R-HSA-5218921]
[PUBMED:22866201]
[PUBMED:22180219]
[PUBMED:22762016]
VEGFR3 signaling in lymphatic endothelium
[NCBI:137996]
[Pathway Interaction Database:lymphangiogenesis_pathway]
[PUBMED:12881528]
[PUBMED:8617204]
[PUBMED:10449752]
[PUBMED:9247316]
[PUBMED:11335727]
[PUBMED:9012504]
[PUBMED:9435229]
[PUBMED:16076871]
[PUBMED:11532940]
[PUBMED:9927207]
[PUBMED:11553610]
[PUBMED:7675451]
[PUBMED:8662748]
[PUBMED:16633338]
amb2 Integrin signaling
[NCBI:137945]
[Pathway Interaction Database:amb2_neutrophils_pathway]
[PUBMED:15004192]
[PUBMED:16260637]
[PUBMED:8874219]
[PUBMED:12736251]
[PUBMED:12824186]
[PUBMED:17202407]
[PUBMED:15458976]
[PUBMED:12208882]
[PUBMED:10985384]
[PUBMED:8598477]
[PUBMED:8157977]
[PUBMED:14530377]
[PUBMED:16567504]
[PUBMED:7836767]
[PUBMED:17003381]
[PUBMED:10899906]
[PUBMED:15741160]
[PUBMED:9920836]
[PUBMED:12941957]
[PUBMED:12773513]
[PUBMED:15283855]
[PUBMED:16854414]
[PUBMED:15217824]
[PUBMED:15090462]
[PUBMED:14769799]
[PUBMED:16905120]
[PUBMED:9831565]
[PUBMED:12194823]
[PUBMED:17268551]
[PUBMED:17133598]
[PUBMED:15153528]
[PUBMED:11418469]
[PUBMED:14623906]
[PUBMED:12036876]
[PUBMED:16391519]
[PUBMED:15304494]
[PUBMED:16093349]
[PUBMED:16403785]
p130Cas linkage to MAPK signaling for integrins
[NCBI:1269361]
[REACTOME:R-HSA-372708]
[PUBMED:16581250]
