full name
X-ray repair cross complementing 5

synonyms
KARP-1, KARP1, KU80, Ku86, KUB2, NFIV, XRCC5, ENSG00000079246

HGNC
HGNC:12833

Entrez Gene
Gene:7520

ENSEMBL
ENSG00000079246

location
chr: 2
start: 216972381
stop: 217071016
strand: +

transcripts
NM_021141.3

pathways
2-LTR circle formation [NCBI:1269067] [REACTOME:R-HSA-164843] [PUBMED:16175173] [PUBMED:16291214]
BARD1 signaling events [NCBI:137959] [Pathway Interaction Database:bard1pathway] [PUBMED:12086603] [PUBMED:15159397] [PUBMED:12732733] [PUBMED:14988723] [PUBMED:14647430] [PUBMED:11927591] [PUBMED:12183411] [PUBMED:8944023] [PUBMED:11278247] [PUBMED:15632137] [PUBMED:9811458] [PUBMED:12154023] [PUBMED:15905410] [PUBMED:12612651] [PUBMED:15665273] [PUBMED:12354784] [PUBMED:10910365] [PUBMED:16391231] [PUBMED:12431996] [PUBMED:15782130] [PUBMED:15184379] [PUBMED:11301010] [PUBMED:9267023] [PUBMED:15886201] [PUBMED:11943588] [PUBMED:10477523] [PUBMED:9738006] [PUBMED:11239454] [PUBMED:10764811]
Coregulation of Androgen receptor activity [NCBI:138085] [Pathway Interaction Database:ar_pathway] [PUBMED:16724108] [PUBMED:16027218] [PUBMED:11818503] [PUBMED:17277772] [PUBMED:11719514] [PUBMED:15833840] [PUBMED:16384856] [PUBMED:14645241] [PUBMED:12218053] [PUBMED:11016951] [PUBMED:12621049] [PUBMED:15784617] [PUBMED:16446156] [PUBMED:17110431] [PUBMED:16254014] [PUBMED:17698582] [PUBMED:15131260] [PUBMED:16705743] [PUBMED:11682623] [PUBMED:17192406] [PUBMED:15882980] [PUBMED:10934038] [PUBMED:12165860] [PUBMED:11856738] [PUBMED:16720717] [PUBMED:9710597] [PUBMED:14609956] [PUBMED:17170703] [PUBMED:10383460] [PUBMED:14576337] [PUBMED:12941811] [PUBMED:14612401] [PUBMED:17975004] [PUBMED:12799378] [PUBMED:15790678] [PUBMED:8643607] [PUBMED:11792840] [PUBMED:16603237] [PUBMED:16079795] [PUBMED:16951154] [PUBMED:15166229] [PUBMED:17142810] [PUBMED:12361945] [PUBMED:11439351] [PUBMED:15640154] [PUBMED:17909037] [PUBMED:15539430] [PUBMED:11792709] [PUBMED:11931767] [PUBMED:10344732] [PUBMED:10428808]
Cytosolic sensors of pathogen-associated DNA [NCBI:1269268] [REACTOME:R-HSA-1834949] [PUBMED:23706668] [PUBMED:21533068] [PUBMED:23706667]
DNA Double-Strand Break Repair [NCBI:1309095] [REACTOME:R-HSA-5693532] [PUBMED:12897142] [PUBMED:20965415]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Early Phase of HIV Life Cycle [NCBI:1269059] [REACTOME:R-HSA-162594] [PUBMED:12091904]
HIV Infection [NCBI:1269057] [REACTOME:R-HSA-162906] [PUBMED:16354571] [PUBMED:9759480]
HIV Life Cycle [NCBI:1269058] [REACTOME:R-HSA-162587] [PUBMED:9188609] [PUBMED:9759480]
IRF3-mediated induction of type I IFN [NCBI:1269273] [REACTOME:R-HSA-3270619] [PUBMED:22394562]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Infectious disease [NCBI:1269056] [REACTOME:R-HSA-5663205]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Integration of provirus [NCBI:1269065] [REACTOME:R-HSA-162592] [PUBMED:16291214]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Non-homologous end-joining [NCBI:83047] [KEGG:hsa03450] [PUBMED:17506672] [PUBMED:15578053] [PUBMED:16971555] [PUBMED:17589524] [PUBMED:12215643] [PUBMED:16895466]
Nonhomologous End-Joining (NHEJ) [NCBI:1309110] [REACTOME:R-HSA-5693571] [PUBMED:10802669] [PUBMED:21293379] [PUBMED:16914548] [PUBMED:12509254] [PUBMED:12607005] [PUBMED:17470781] [PUBMED:12364621] [PUBMED:11493912] [PUBMED:23333306] [PUBMED:22179609] [PUBMED:25512557] [PUBMED:22529269] [PUBMED:23505375] [PUBMED:15574327] [PUBMED:12077346] [PUBMED:11030616] [PUBMED:14561766] [PUBMED:8422676] [PUBMED:23727112] [PUBMED:17525340] [PUBMED:23306437] [PUBMED:10757784] [PUBMED:16439205] [PUBMED:10959836] [PUBMED:15790808] [PUBMED:16377563] [PUBMED:11955432] [PUBMED:22373579] [PUBMED:19001859] [PUBMED:12023295] [PUBMED:15451442] [PUBMED:16093244] [PUBMED:10572166]
Regulation of Telomerase [NCBI:137987] [Pathway Interaction Database:telomerasepathway] [PUBMED:12037663] [PUBMED:11191110] [PUBMED:15381700] [PUBMED:10637317] [PUBMED:15314656] [PUBMED:10601322] [PUBMED:12545159] [PUBMED:11110707] [PUBMED:15371341] [PUBMED:12681489] [PUBMED:15824061] [PUBMED:15048073] [PUBMED:10850490] [PUBMED:16730176] [PUBMED:12181313] [PUBMED:16890531] [PUBMED:9837921] [PUBMED:10224060] [PUBMED:15331176] [PUBMED:16522649] [PUBMED:9822378] [PUBMED:15316005] [PUBMED:12699629] [PUBMED:16843438] [PUBMED:12151407] [PUBMED:12135483] [PUBMED:15655249] [PUBMED:10888888] [PUBMED:16765199] [PUBMED:16869756] [PUBMED:10837221] [PUBMED:16135795] [PUBMED:11074006] [PUBMED:11191109] [PUBMED:14712220] [PUBMED:16508638] [PUBMED:10471503] [PUBMED:11854288] [PUBMED:16785237] [PUBMED:9130722] [PUBMED:12956959] [PUBMED:15710386] [PUBMED:12586360] [PUBMED:12377759] [PUBMED:11433024] [PUBMED:15843522] [PUBMED:14749375] [PUBMED:11274138] [PUBMED:12676087] [PUBMED:16166375] [PUBMED:15371412]
STING mediated induction of host immune responses [NCBI:1269272] [REACTOME:R-HSA-1834941] [PUBMED:19776740] [PUBMED:22607800] [PUBMED:18724357] [PUBMED:21947006] [PUBMED:22394562] [PUBMED:23585680] [PUBMED:23478444] [PUBMED:19433799] [PUBMED:20107183] [PUBMED:21820332] [PUBMED:20871604] [PUBMED:19926846] [PUBMED:21892174] [PUBMED:22706339] [PUBMED:20890285] [PUBMED:23604073]