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Genes
DVL1
Gene - DVL1
full name
dishevelled segment polarity protein 1
synonyms
DVL, DVL1L1, DVL1P1, DVL1, ENSG00000107404
HGNC
HGNC:3084
Entrez Gene
Gene:1855
ENSEMBL
ENSG00000107404
location
chr: 1
start: 1270658
stop: 1284509
strand: -
OMIM
OMIM:601365
: DVL1
OMIM:616331
: Robinow syndrome, autosomal dominant 2
transcripts
NM_004421.2
pathways
Basal cell carcinoma
[NCBI:83113]
[KEGG:hsa05217]
[PUBMED:15948971]
[PUBMED:15978322]
[PUBMED:15468170]
[PUBMED:11276000]
[PUBMED:11130178]
[PUBMED:14737121]
[PUBMED:15270885]
[PUBMED:16306523]
[PUBMED:14556242]
[PUBMED:15656799]
[PUBMED:16054233]
[PUBMED:12588368]
[PUBMED:16881963]
[PUBMED:11736900]
Beta-catenin independent WNT signaling
[NCBI:1269610]
[REACTOME:R-HSA-3858494]
[PUBMED:22935904]
[PUBMED:21903638]
[PUBMED:23256519]
[PUBMED:8065359]
[PUBMED:7739543]
[PUBMED:23140633]
Breast cancer
[NCBI:1435207]
[KEGG:hsa05224]
[PUBMED:24649067]
[PUBMED:26040571]
[PUBMED:11879567]
[PUBMED:22722193]
[PUBMED:26028978]
[PUBMED:25013431]
[PUBMED:11737884]
[PUBMED:23702927]
[PUBMED:21076461]
[PUBMED:21898546]
[PUBMED:27390604]
[PUBMED:24291072]
[PUBMED:26968398]
[PUBMED:20087430]
[PUBMED:23000897]
[PUBMED:25544707]
[PUBMED:24596345]
[PUBMED:23988612]
[PUBMED:24111892]
[PUBMED:25907219]
[PUBMED:15343273]
[PUBMED:21965336]
[PUBMED:23881035]
[PUBMED:23196196]
[PUBMED:22178455]
[PUBMED:20436504]
[PUBMED:19088017]
[PUBMED:16113099]
[PUBMED:20971825]
Canonical Wnt signaling pathway
[NCBI:138032]
[Pathway Interaction Database:wnt_canonical_pathway]
[PUBMED:16849322]
[PUBMED:10228155]
[PUBMED:11007767]
[PUBMED:10023673]
[PUBMED:19061640]
[PUBMED:10074433]
[PUBMED:9554852]
[PUBMED:10196136]
[PUBMED:18772438]
[PUBMED:19309792]
[PUBMED:16263762]
[PUBMED:16890161]
[PUBMED:16341017]
[PUBMED:17569865]
[PUBMED:16314428]
[PUBMED:17529994]
[PUBMED:10421629]
[PUBMED:11751573]
[PUBMED:20177058]
[PUBMED:15024404]
[PUBMED:12000790]
[PUBMED:19107203]
[PUBMED:10684251]
[PUBMED:9482734]
[PUBMED:16547521]
[PUBMED:10092233]
[PUBMED:18077588]
[PUBMED:16303557]
[PUBMED:19556239]
[PUBMED:19561074]
[PUBMED:11274398]
[PUBMED:14966280]
[PUBMED:9566905]
[PUBMED:11834740]
[PUBMED:19801552]
[PUBMED:12554650]
[PUBMED:16341016]
[PUBMED:17510365]
[PUBMED:15459103]
[PUBMED:18929646]
[PUBMED:15327768]
[PUBMED:9312064]
Degradation of DVL
[NCBI:1269605]
[REACTOME:R-HSA-4641258]
[PUBMED:14684739]
[PUBMED:20006983]
[PUBMED:22826439]
[PUBMED:11970895]
[PUBMED:16547521]
[PUBMED:16446366]
Disassembly of the destruction complex and recruitment of AXIN to the membrane
[NCBI:1269601]
[REACTOME:R-HSA-4641262]
[PUBMED:10647780]
[PUBMED:10581160]
[PUBMED:14551908]
[PUBMED:15084453]
[PUBMED:19619488]
[PUBMED:19759537]
[PUBMED:14731402]
[PUBMED:18234723]
[PUBMED:15459103]
[PUBMED:22363759]
[PUBMED:17318175]
[PUBMED:11336703]
[PUBMED:16341017]
[PUBMED:10421629]
[PUBMED:17569865]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Hippo signaling pathway
[NCBI:749777]
[KEGG:hsa04390]
[PUBMED:18955139]
[PUBMED:20439427]
[PUBMED:20951342]
[PUBMED:21138973]
[PUBMED:18328423]
[PUBMED:21324984]
[PUBMED:23034192]
[PUBMED:21808241]
[PUBMED:17975546]
[PUBMED:22750148]
[PUBMED:21084559]
[PUBMED:19846288]
[PUBMED:22895435]
[PUBMED:22683405]
[PUBMED:22658639]
[PUBMED:22153608]
[PUBMED:20945341]
[PUBMED:22830020]
[PUBMED:21874053]
[PUBMED:21376238]
Melanogenesis
[NCBI:83092]
[KEGG:hsa04916]
[PUBMED:11041354]
[PUBMED:10347209]
[PUBMED:15016298]
[PUBMED:11023702]
[PUBMED:11602344]
[PUBMED:12753399]
[PUBMED:10841026]
[PUBMED:16822996]
[PUBMED:15383650]
[PUBMED:9263329]
[PUBMED:16246839]
[PUBMED:10643996]
[PUBMED:12894244]
Negative regulation of TCF-dependent signaling by DVL-interacting proteins
[NCBI:1269609]
[REACTOME:R-HSA-5368598]
[PUBMED:14750955]
[PUBMED:19619488]
[PUBMED:21031079]
[PUBMED:20006983]
[PUBMED:11113207]
[PUBMED:22643886]
Noncanonical Wnt signaling pathway
[NCBI:169354]
[Pathway Interaction Database:wnt_noncanonical_pathway]
[PUBMED:11408485]
[PUBMED:20457807]
[PUBMED:17646398]
[PUBMED:15509575]
[PUBMED:10391247]
[PUBMED:12482967]
[PUBMED:10777564]
[PUBMED:19720827]
[PUBMED:18667433]
[PUBMED:18162551]
[PUBMED:18215320]
[PUBMED:17101698]
[PUBMED:12839624]
[PUBMED:19910923]
[PUBMED:10395542]
[PUBMED:15121866]
[PUBMED:11779461]
[PUBMED:16880514]
[PUBMED:18606138]
[PUBMED:12771126]
[PUBMED:18615587]
[PUBMED:17952062]
Notch signaling pathway
[NCBI:83062]
[KEGG:hsa04330]
[NCBI:169345]
[Pathway Interaction Database:notch_pathway]
[PUBMED:11459941]
[PUBMED:12682059]
[PUBMED:11825871]
[PUBMED:17658278]
[PUBMED:15998794]
[PUBMED:11101851]
[PUBMED:19686683]
[PUBMED:18490439]
[PUBMED:11150244]
[PUBMED:9694793]
[PUBMED:10206645]
[PUBMED:19704010]
[PUBMED:16137758]
[PUBMED:15288258]
[PUBMED:17392792]
[PUBMED:8749394]
[PUBMED:15965470]
[PUBMED:14566063]
[PUBMED:19567869]
[PUBMED:11585921]
[PUBMED:18676613]
[PUBMED:12913000]
[PUBMED:10593990]
[PUBMED:15274632]
[PUBMED:11777909]
[PUBMED:12015972]
[PUBMED:10028969]
[PUBMED:18043734]
[PUBMED:17658279]
[PUBMED:17575125]
[PUBMED:10958687]
[PUBMED:15300010]
[PUBMED:10882062]
[PUBMED:12374742]
[PUBMED:11782429]
[PUBMED:9653148]
[PUBMED:9315665]
[PUBMED:8643690]
[PUBMED:17114293]
[PUBMED:10837024]
[PUBMED:15067010]
[PUBMED:17296795]
[PUBMED:10940313]
[PUBMED:18628966]
[PUBMED:12826675]
[PUBMED:12681948]
[PUBMED:16492672]
[PUBMED:12551931]
[PUBMED:15082708]
[PUBMED:12464310]
[PUBMED:12794186]
[PUBMED:16107360]
[PUBMED:19726682]
[PUBMED:11486031]
[PUBMED:16287852]
[PUBMED:12297508]
[PUBMED:16061358]
[PUBMED:17107962]
[PUBMED:9244302]
[PUBMED:11425854]
[PUBMED:9620803]
[PUBMED:15272268]
[PUBMED:18417156]
[PUBMED:16000382]
[PUBMED:11896183]
[PUBMED:11604511]
[PUBMED:16847353]
[PUBMED:11432830]
[PUBMED:15652348]
[PUBMED:12417415]
[PUBMED:14567914]
[PUBMED:11006133]
[PUBMED:18077452]
[PUBMED:16144902]
[PUBMED:15288257]
[PUBMED:15585829]
[PUBMED:12370315]
[PUBMED:15288260]
[PUBMED:17434929]
[PUBMED:12814948]
[PUBMED:10882063]
[PUBMED:11518718]
PCP/CE pathway
[NCBI:1269611]
[REACTOME:R-HSA-4086400]
[PUBMED:23140633]
[PUBMED:18848778]
[PUBMED:10811221]
[PUBMED:19365405]
[PUBMED:9598355]
[PUBMED:21983142]
[PUBMED:17433286]
[PUBMED:20004982]
[PUBMED:19204114]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Presenilin action in Notch and Wnt signaling
[NCBI:137914]
[Pathway Interaction Database:ps1pathway]
[PUBMED:10391247]
[PUBMED:11921277]
[PUBMED:11357136]
[PUBMED:15620650]
[PUBMED:11739397]
[PUBMED:15747065]
[PUBMED:10359821]
[PUBMED:15327768]
[PUBMED:12554650]
[PUBMED:15292388]
[PUBMED:11266469]
[PUBMED:12794186]
[PUBMED:10882062]
[PUBMED:8923452]
[PUBMED:12050670]
[PUBMED:10201374]
[PUBMED:12857724]
[PUBMED:9171444]
RHO GTPase Effectors
[NCBI:1269509]
[REACTOME:R-HSA-195258]
[PUBMED:9694656]
[PUBMED:18066052]
[PUBMED:11018042]
[PUBMED:10470034]
[PUBMED:8702756]
[PUBMED:21730051]
[PUBMED:8571126]
[PUBMED:19513348]
[PUBMED:17244649]
[PUBMED:11145705]
[PUBMED:24128008]
[PUBMED:23716662]
[PUBMED:8617235]
[PUBMED:8543060]
[PUBMED:11804587]
[PUBMED:24969695]
[PUBMED:12635176]
[PUBMED:12778124]
[PUBMED:18006505]
[PUBMED:1660188]
[PUBMED:21351730]
[PUBMED:16507994]
[PUBMED:14595335]
[PUBMED:10072071]
[PUBMED:10591629]
[PUBMED:10753910]
[PUBMED:23875749]
[PUBMED:17151359]
[PUBMED:10652353]
[PUBMED:12221077]
[PUBMED:10559936]
[PUBMED:12783890]
[PUBMED:11948177]
[PUBMED:18237546]
[PUBMED:16079795]
[PUBMED:10924361]
[PUBMED:14514689]
[PUBMED:8107774]
[PUBMED:8756646]
[PUBMED:16979770]
[PUBMED:16636067]
[PUBMED:9751706]
[PUBMED:10619026]
[PUBMED:23444367]
[PUBMED:15546864]
[PUBMED:12473120]
[PUBMED:8816443]
[PUBMED:9199170]
[PUBMED:12514133]
[PUBMED:16762923]
[PUBMED:12110184]
[PUBMED:16431929]
[PUBMED:10975528]
[PUBMED:10940294]
[PUBMED:9535855]
[PUBMED:7559638]
[PUBMED:11162552]
[PUBMED:19737400]
[PUBMED:9988689]
[PUBMED:12732141]
[PUBMED:8798539]
[PUBMED:24914801]
[PUBMED:11689693]
[PUBMED:8769096]
[PUBMED:9368021]
RHO GTPases Activate Formins
[NCBI:1269519]
[REACTOME:R-HSA-5663220]
[PUBMED:20233848]
[PUBMED:15507212]
[PUBMED:16292343]
[PUBMED:12906795]
[PUBMED:11779461]
[PUBMED:21397845]
[PUBMED:12577064]
[PUBMED:17198702]
[PUBMED:15006353]
[PUBMED:20101212]
[PUBMED:15944396]
[PUBMED:10678165]
[PUBMED:16943183]
[PUBMED:16439214]
[PUBMED:16472745]
[PUBMED:10958683]
[PUBMED:12732141]
[PUBMED:15085137]
[PUBMED:24914801]
[PUBMED:9497258]
[PUBMED:21576392]
[PUBMED:21868368]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Signaling by Wnt
[NCBI:1269594]
[REACTOME:R-HSA-195721]
[PUBMED:19530173]
[PUBMED:23256519]
[PUBMED:22952392]
[PUBMED:19204114]
[PUBMED:19365405]
[PUBMED:19619488]
[PUBMED:17143292]
[PUBMED:17230199]
[PUBMED:18710302]
[PUBMED:16099039]
[PUBMED:20576942]
[PUBMED:10858654]
[PUBMED:12967557]
Signaling pathways regulating pluripotency of stem cells
[NCBI:1026136]
[KEGG:hsa04550]
[PUBMED:20705693]
[PUBMED:23653415]
[PUBMED:16518401]
[PUBMED:17211451]
[PUBMED:22649650]
[PUBMED:24910449]
[PUBMED:19551525]
[PUBMED:22298652]
[PUBMED:23370346]
[PUBMED:24315442]
[PUBMED:18414030]
[PUBMED:17647265]
[PUBMED:18295576]
[PUBMED:24957798]
[PUBMED:24147644]
[PUBMED:16153702]
[PUBMED:19427042]
[PUBMED:18220859]
[PUBMED:19571885]
[PUBMED:23585347]
TCF dependent signaling in response to WNT
[NCBI:1269599]
[REACTOME:R-HSA-201681]
[PUBMED:19619488]
[PUBMED:23256519]
[PUBMED:23343194]
WNT mediated activation of DVL
[NCBI:1269600]
[REACTOME:R-HSA-201688]
[PUBMED:15935773]
[PUBMED:18093802]
[PUBMED:18772438]
[PUBMED:11336703]
[PUBMED:11433294]
[PUBMED:10990458]
[PUBMED:22017973]
[PUBMED:20006983]
[PUBMED:17529994]
[PUBMED:14636582]
[PUBMED:19561074]
[PUBMED:15459103]
[PUBMED:9214626]
Wnt signaling pathway
[NCBI:83061]
[KEGG:hsa04310]
[PUBMED:12446114]
[PUBMED:14745971]
[PUBMED:14530294]
[PUBMED:15102436]
[PUBMED:14635791]
[PUBMED:19482104]
[PUBMED:23256519]
[PUBMED:12967557]
[PUBMED:11433294]
[PUBMED:18838381]
mTOR signaling pathway
[NCBI:83059]
[KEGG:hsa04150]
[NCBI:138001]
[Pathway Interaction Database:mtor_4pathway]
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