full name
8-oxoguanine DNA glycosylase

synonyms
HMMH, HOGG1, MUTM, OGH1, OGG1, ENSG00000114026

HGNC
HGNC:8125

Entrez Gene
Gene:4968

ENSEMBL
ENSG00000114026

location
chr: 3
start: 9791628
stop: 9829468
strand: +

OMIM
OMIM:601982: OGG1 (Sporadic)
OMIM:144700: Renal cell carcinoma, clear cell, somatic

transcripts
NM_016828.2
NM_016829.2
NM_016821.2
NM_016826.2
NM_016827.2
NM_016819.3
NM_016820.3
NM_002542.5

pathways
APEX1-Independent Resolution of AP Sites via the Single Nucleotide Replacement Pathway [NCBI:1270363] [REACTOME:R-HSA-5649702] [PUBMED:16982218] [PUBMED:15260972] [PUBMED:11163244]
Base Excision Repair [NCBI:1270351] [REACTOME:R-HSA-73884] [PUBMED:11937636] [PUBMED:10583946]
Base excision repair [NCBI:83043] [KEGG:hsa03410] [PUBMED:17893748] [PUBMED:11436317] [PUBMED:17337257] [PUBMED:21665970]
Base-Excision Repair, AP Site Formation [NCBI:1270352] [REACTOME:R-HSA-73929] [PUBMED:10583946] [PUBMED:11937636]
Cleavage of the damaged purine [NCBI:1270355] [REACTOME:R-HSA-110331] [PUBMED:8016081] [PUBMED:10583946]
Cleavage of the damaged pyrimidine [NCBI:1270358] [REACTOME:R-HSA-110329] [PUBMED:10583946]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Depurination [NCBI:1270353] [REACTOME:R-HSA-73927] [PUBMED:8900285] [PUBMED:9724657]
Depyrimidination [NCBI:1270356] [REACTOME:R-HSA-73928] [PUBMED:10583946]
Displacement of DNA glycosylase by APEX1 [NCBI:1270360] [REACTOME:R-HSA-110357] [PUBMED:9724657]
Recognition and association of DNA glycosylase with site containing an affected purine [NCBI:1270354] [REACTOME:R-HSA-110330] [PUBMED:8900285] [PUBMED:9724657]
Recognition and association of DNA glycosylase with site containing an affected pyrimidine [NCBI:1270357] [REACTOME:R-HSA-110328] [PUBMED:11937636]
Resolution of Abasic Sites (AP sites) [NCBI:1270359] [REACTOME:R-HSA-73933] [PUBMED:11601988] [PUBMED:15260972] [PUBMED:17395641] [PUBMED:19329425] [PUBMED:9804798] [PUBMED:15556996] [PUBMED:9214649] [PUBMED:7608159] [PUBMED:11440997] [PUBMED:15871698] [PUBMED:9207062] [PUBMED:16982218] [PUBMED:8978692]