full name
N-glycanase 1

synonyms
CDG1V, PNG1, PNGase, NGLY1, ENSG00000151092

HGNC
HGNC:17646

Entrez Gene
Gene:55768

ENSEMBL
ENSG00000151092

location
chr: 3
start: 25760435
stop: 25831530
strand: -

OMIM
OMIM:610661: NGLY1 (Autosomal recessive inheritance)
OMIM:615273: Congenital disorder of deglycosylation

transcripts
NM_001145294.1
NM_001145295.1
NM_018297.3
NM_001145293.1

pathways
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:16807922] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
N-glycan trimming in the ER and Calnexin/Calreticulin cycle [NCBI:1268722] [REACTOME:R-HSA-532668] [PUBMED:18303019]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Protein processing in endoplasmic reticulum [NCBI:167325] [KEGG:hsa04141] [PUBMED:20347046] [PUBMED:18023214] [PUBMED:20219571] [PUBMED:19491040] [PUBMED:20112977]