Logo
full name
glycogen synthase kinase 3 beta

synonyms
GSK3B, ENSG00000082701

HGNC
HGNC:4617

Entrez Gene
Gene:2932

ENSEMBL
ENSG00000082701

location
chr: 3
start: 119540800
stop: 119813264
strand: -

transcripts
NM_001146156.1
NM_002093.3

pathways
AKT phosphorylates targets in the cytosol [NCBI:1269189] [REACTOME:R-HSA-198323]
AMER1 mutants destabilize the destruction complex [NCBI:1268913] [REACTOME:R-HSA-4839748] [PUBMED:17510365] [PUBMED:21248786] [PUBMED:23256519]
APC truncation mutants have impaired AXIN binding [NCBI:1268909] [REACTOME:R-HSA-5467337] [PUBMED:10921899] [PUBMED:1338904] [PUBMED:11057903] [PUBMED:10213492] [PUBMED:8111410]
AXIN missense mutants destabilize the destruction complex [NCBI:1268912] [REACTOME:R-HSA-5467340] [PUBMED:12101426] [PUBMED:10862053] [PUBMED:11746989] [PUBMED:10700176]
AXIN mutants destabilize the destruction complex, activating WNT signaling [NCBI:1268910] [REACTOME:R-HSA-4839735] [PUBMED:15735151] [PUBMED:23256519] [PUBMED:12101426] [PUBMED:11746989] [PUBMED:10700176] [PUBMED:11585731]
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Alzheimer's disease [NCBI:83097] [KEGG:hsa05010] [PUBMED:18782350] [PUBMED:18035450] [PUBMED:15177383] [PUBMED:10527810] [PUBMED:15363492] [PUBMED:16677790] [PUBMED:15295589] [PUBMED:17055782] [PUBMED:15864339] [PUBMED:15750290] [PUBMED:18675468] [PUBMED:15232608] [PUBMED:9848086] [PUBMED:11484003] [PUBMED:10830966] [PUBMED:16529745] [PUBMED:17568632]
Aurora A signaling [NCBI:137925] [Pathway Interaction Database:aurora_a_pathway] [PUBMED:17308110] [PUBMED:16894566] [PUBMED:16631581] [PUBMED:17229885] [PUBMED:15128871] [PUBMED:14990569] [PUBMED:12177045] [PUBMED:14580337] [PUBMED:14724178] [PUBMED:17545617] [PUBMED:15687499] [PUBMED:11163242] [PUBMED:14603251] [PUBMED:17060449] [PUBMED:12208850] [PUBMED:12815066] [PUBMED:17125467] [PUBMED:13678582] [PUBMED:15987997] [PUBMED:15966895] [PUBMED:11976319] [PUBMED:14702041] [PUBMED:16246726] [PUBMED:17452972] [PUBMED:12082625] [PUBMED:11039908] [PUBMED:14667408] [PUBMED:12577065] [PUBMED:14600264] [PUBMED:11756469] [PUBMED:16772293] [PUBMED:12023018] [PUBMED:15469940] [PUBMED:16082213]
Axon guidance [NCBI:83065] [KEGG:hsa04360] [NCBI:1270303] [REACTOME:R-HSA-422475] [PUBMED:14682358] [PUBMED:15084255] [PUBMED:11687826] [PUBMED:15818466] [PUBMED:15363605] [PUBMED:12471249] [PUBMED:15630019] [PUBMED:11891122] [PUBMED:15960985] [PUBMED:12677003]
B cell receptor signaling pathway [NCBI:83081] [KEGG:hsa04662] [PUBMED:15626471] [PUBMED:12119152] [PUBMED:15886119] [PUBMED:12461567] [PUBMED:9697839] [PUBMED:15752555] [PUBMED:11163197] [PUBMED:18086859] [PUBMED:15364057] [PUBMED:15457440] [PUBMED:15322145] [PUBMED:15771577] [PUBMED:12033741] [PUBMED:15886112] [PUBMED:10358768]
B-WICH complex positively regulates rRNA expression [NCBI:1339126] [REACTOME:R-HSA-5250924] [PUBMED:23555303] [PUBMED:21559432] [PUBMED:16514417] [PUBMED:23667505] [PUBMED:16603771] [PUBMED:16574391]
BMP receptor signaling [NCBI:137948] [Pathway Interaction Database:bmppathway] [PUBMED:9136927] [PUBMED:12857866] [PUBMED:11158580] [PUBMED:10748465] [PUBMED:11401399] [PUBMED:9442019] [PUBMED:10814522] [PUBMED:8752214] [PUBMED:9660951] [PUBMED:17085434] [PUBMED:11714695] [PUBMED:7644468] [PUBMED:15671031] [PUBMED:8065329] [PUBMED:16604073] [PUBMED:8006002] [PUBMED:9436979] [PUBMED:9689081] [PUBMED:9335505] [PUBMED:17289590] [PUBMED:8893010] [PUBMED:16931515] [PUBMED:10748100] [PUBMED:15020244] [PUBMED:11121043] [PUBMED:15975920] [PUBMED:7937936] [PUBMED:11016919] [PUBMED:8752213] [PUBMED:7673243] [PUBMED:10519551] [PUBMED:8662721] [PUBMED:9878061] [PUBMED:17356069] [PUBMED:7791754] [PUBMED:8653785] [PUBMED:10504300] [PUBMED:10458166]
Basal cell carcinoma [NCBI:83113] [KEGG:hsa05217] [PUBMED:15948971] [PUBMED:15978322] [PUBMED:15468170] [PUBMED:11276000] [PUBMED:11130178] [PUBMED:14737121] [PUBMED:15270885] [PUBMED:16306523] [PUBMED:14556242] [PUBMED:15656799] [PUBMED:16054233] [PUBMED:12588368] [PUBMED:16881963] [PUBMED:11736900]
Beta-catenin phosphorylation cascade [NCBI:1269597] [REACTOME:R-HSA-196299] [PUBMED:11955436] [PUBMED:12000790]
Breast cancer [NCBI:1435207] [KEGG:hsa05224] [PUBMED:24649067] [PUBMED:26040571] [PUBMED:11879567] [PUBMED:22722193] [PUBMED:26028978] [PUBMED:25013431] [PUBMED:11737884] [PUBMED:23702927] [PUBMED:21076461] [PUBMED:21898546] [PUBMED:27390604] [PUBMED:24291072] [PUBMED:26968398] [PUBMED:20087430] [PUBMED:23000897] [PUBMED:25544707] [PUBMED:24596345] [PUBMED:23988612] [PUBMED:24111892] [PUBMED:25907219] [PUBMED:15343273] [PUBMED:21965336] [PUBMED:23881035] [PUBMED:23196196] [PUBMED:22178455] [PUBMED:20436504] [PUBMED:19088017] [PUBMED:16113099] [PUBMED:20971825]
C-MYC pathway [NCBI:169344] [Pathway Interaction Database:myc_pathway] [PUBMED:17558397] [PUBMED:10611234] [PUBMED:14563837] [PUBMED:12660246] [PUBMED:11018017] [PUBMED:12769844] [PUBMED:11445536] [PUBMED:17967894] [PUBMED:15199070] [PUBMED:17146439] [PUBMED:9708738] [PUBMED:20008325] [PUBMED:19131971] [PUBMED:12177005] [PUBMED:15048125] [PUBMED:15361884] [PUBMED:14749374] [PUBMED:15150404] [PUBMED:15103331] [PUBMED:12776177] [PUBMED:11673469] [PUBMED:9312026] [PUBMED:17597761] [PUBMED:12769843] [PUBMED:9927431] [PUBMED:10882073] [PUBMED:16537924]
CDC42 signaling events [NCBI:137994] [Pathway Interaction Database:cdc42_pathway] [PUBMED:7629060] [PUBMED:7652575] [PUBMED:8653792] [PUBMED:18448434] [PUBMED:19822663] [PUBMED:19454477] [PUBMED:18662680] [PUBMED:15882626] [PUBMED:11948177] [PUBMED:9860974] [PUBMED:15225553] [PUBMED:8643625] [PUBMED:8107774] [PUBMED:8670801] [PUBMED:8034624] [PUBMED:10934474] [PUBMED:10734320] [PUBMED:17522712] [PUBMED:11525734] [PUBMED:15649357] [PUBMED:10473551] [PUBMED:16157700] [PUBMED:9822598] [PUBMED:15723051] [PUBMED:7600582] [PUBMED:18319301] [PUBMED:9042860] [PUBMED:10613909] [PUBMED:17580073] [PUBMED:12745076] [PUBMED:16253996] [PUBMED:10840034] [PUBMED:10360579] [PUBMED:11907268] [PUBMED:10934475] [PUBMED:10219243] [PUBMED:17038317] [PUBMED:8910292] [PUBMED:9403696] [PUBMED:11285260] [PUBMED:10995437] [PUBMED:9368021] [PUBMED:14970210] [PUBMED:9694656] [PUBMED:14505571] [PUBMED:17115031] [PUBMED:9317150] [PUBMED:14653992] [PUBMED:17081755] [PUBMED:12676083] [PUBMED:18216334] [PUBMED:19826000] [PUBMED:8702968] [PUBMED:11304531] [PUBMED:10973943] [PUBMED:11309380] [PUBMED:18586681] [PUBMED:15479449] [PUBMED:19097998] [PUBMED:16892055] [PUBMED:17244649] [PUBMED:8625410] [PUBMED:8497321] [PUBMED:15485841] [PUBMED:16407834] [PUBMED:11804587] [PUBMED:9867866] [PUBMED:10747870] [PUBMED:7600581] [PUBMED:12610628] [PUBMED:19435802] [PUBMED:15572110] [PUBMED:7592586] [PUBMED:11696321] [PUBMED:10559936]
CRMPs in Sema3A signaling [NCBI:1270310] [REACTOME:R-HSA-399956] [PUBMED:17607942]
Canonical Wnt signaling pathway [NCBI:138032] [Pathway Interaction Database:wnt_canonical_pathway] [PUBMED:16849322] [PUBMED:10228155] [PUBMED:11007767] [PUBMED:10023673] [PUBMED:19061640] [PUBMED:10074433] [PUBMED:9554852] [PUBMED:10196136] [PUBMED:18772438] [PUBMED:19309792] [PUBMED:16263762] [PUBMED:16890161] [PUBMED:16341017] [PUBMED:17569865] [PUBMED:16314428] [PUBMED:17529994] [PUBMED:10421629] [PUBMED:11751573] [PUBMED:20177058] [PUBMED:15024404] [PUBMED:12000790] [PUBMED:19107203] [PUBMED:10684251] [PUBMED:9482734] [PUBMED:16547521] [PUBMED:10092233] [PUBMED:18077588] [PUBMED:16303557] [PUBMED:19556239] [PUBMED:19561074] [PUBMED:11274398] [PUBMED:14966280] [PUBMED:9566905] [PUBMED:11834740] [PUBMED:19801552] [PUBMED:12554650] [PUBMED:16341016] [PUBMED:17510365] [PUBMED:15459103] [PUBMED:18929646] [PUBMED:15327768] [PUBMED:9312064]
Cell cycle [NCBI:83054] [KEGG:hsa04110] [PUBMED:7973727] [PUBMED:17568790] [PUBMED:9832503] [PUBMED:16936746] [PUBMED:9029154] [PUBMED:12573239] [PUBMED:19020303] [PUBMED:9618481] [PUBMED:12809600] [PUBMED:8242749] [PUBMED:10385618] [PUBMED:17426725] [PUBMED:17018296] [PUBMED:16212951] [PUBMED:12925736] [PUBMED:11099028] [PUBMED:15568976] [PUBMED:15838516] [PUBMED:15838523] [PUBMED:15876871] [PUBMED:7908906] [PUBMED:9889196]
Cellular response to heat stress [NCBI:1270421] [REACTOME:R-HSA-3371556] [PUBMED:8455624] [PUBMED:8441385]
Cellular responses to stress [NCBI:1270414] [REACTOME:R-HSA-2262752] [PUBMED:15709958]
Chemokine signaling pathway [NCBI:99051] [KEGG:hsa04062] [PUBMED:17371236] [PUBMED:19159344] [PUBMED:17169327] [PUBMED:10852130] [PUBMED:9765254] [PUBMED:15771581] [PUBMED:14607270] [PUBMED:18662984] [PUBMED:12495636] [PUBMED:15803148] [PUBMED:15046611] [PUBMED:12069927] [PUBMED:18711432] [PUBMED:17675482] [PUBMED:16144840] [PUBMED:17496928] [PUBMED:17537990] [PUBMED:11872087] [PUBMED:12051620] [PUBMED:14625285] [PUBMED:8576262] [PUBMED:11244042]
Class I PI3K signaling events mediated by Akt [NCBI:138020] [Pathway Interaction Database:pi3kciaktpathway] [PUBMED:10102273] [PUBMED:9812896] [PUBMED:15718470] [PUBMED:10485710] [PUBMED:16919458] [PUBMED:16213228] [PUBMED:11154276] [PUBMED:16962653] [PUBMED:9346240] [PUBMED:12244301] [PUBMED:15057270] [PUBMED:10217147] [PUBMED:17407381] [PUBMED:8524413] [PUBMED:16982699] [PUBMED:12637568] [PUBMED:18024423] [PUBMED:10358075] [PUBMED:9637919] [PUBMED:12244302] [PUBMED:9094314] [PUBMED:10576741] [PUBMED:11864996] [PUBMED:11777915] [PUBMED:12244303] [PUBMED:9381178] [PUBMED:11231573] [PUBMED:10949026] [PUBMED:15262962] [PUBMED:9512493] [PUBMED:10783894]
Colorectal cancer [NCBI:83106] [KEGG:hsa05210] [PUBMED:15479695] [PUBMED:11459867] [PUBMED:9196022] [PUBMED:11170304] [PUBMED:12951588] [PUBMED:15349822] [PUBMED:15711891] [PUBMED:16042571] [PUBMED:15000146] [PUBMED:12737309] [PUBMED:10505543] [PUBMED:11078609] [PUBMED:11223406] [PUBMED:16326109] [PUBMED:16699851] [PUBMED:11477132] [PUBMED:12621137] [PUBMED:15573119] [PUBMED:16555243] [PUBMED:15310786]
Constitutive Signaling by AKT1 E17K in Cancer [NCBI:1268881] [REACTOME:R-HSA-5674400] [PUBMED:17611497] [PUBMED:18954143]
DAP12 interactions [NCBI:1269283] [REACTOME:R-HSA-2172127] [PUBMED:19120482] [PUBMED:17220916] [PUBMED:9490415] [PUBMED:18192027] [PUBMED:15884055]
DAP12 signaling [NCBI:1269284] [REACTOME:R-HSA-2424491] [PUBMED:15884055] [PUBMED:17110943] [PUBMED:17220916]
Degradation of GLI2 by the proteasome [NCBI:1269638] [REACTOME:R-HSA-5610783] [PUBMED:19056373] [PUBMED:17283082] [PUBMED:23719536] [PUBMED:16611981]
Degradation of beta-catenin by the destruction complex [NCBI:1269596] [REACTOME:R-HSA-195253] [PUBMED:17143292]
Developmental Biology [NCBI:1270302] [REACTOME:R-HSA-1266738]
Disassembly of the destruction complex and recruitment of AXIN to the membrane [NCBI:1269601] [REACTOME:R-HSA-4641262] [PUBMED:10647780] [PUBMED:10581160] [PUBMED:14551908] [PUBMED:15084453] [PUBMED:19619488] [PUBMED:19759537] [PUBMED:14731402] [PUBMED:18234723] [PUBMED:15459103] [PUBMED:22363759] [PUBMED:17318175] [PUBMED:11336703] [PUBMED:16341017] [PUBMED:10421629] [PUBMED:17569865]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Dopaminergic synapse [NCBI:469199] [KEGG:hsa04728] [PUBMED:20727368] [PUBMED:10433257] [PUBMED:17408758] [PUBMED:15292232] [PUBMED:9457173] [PUBMED:17349698] [PUBMED:15521361] [PUBMED:18353279] [PUBMED:21303898] [PUBMED:19251795] [PUBMED:15381316] [PUBMED:15590733] [PUBMED:20224735] [PUBMED:19138563] [PUBMED:12967774]
Downstream signal transduction [NCBI:1269479] [REACTOME:R-HSA-186763] [PUBMED:10508235] [PUBMED:9739761]
Downstream signaling events of B Cell Receptor (BCR) [NCBI:1269185] [REACTOME:R-HSA-1168372] [PUBMED:17052215] [PUBMED:19909372]
EGFR tyrosine kinase inhibitor resistance [NCBI:1404798] [KEGG:hsa01521] [PUBMED:16843264] [PUBMED:23401451] [PUBMED:20966921] [PUBMED:24307395] [PUBMED:22956644] [PUBMED:25232485] [PUBMED:24493829] [PUBMED:23071030] [PUBMED:18483355] [PUBMED:24202392] [PUBMED:19632948] [PUBMED:23361103] [PUBMED:26579470] [PUBMED:22970367] [PUBMED:23358468] [PUBMED:17554333] [PUBMED:25337673] [PUBMED:22474259] [PUBMED:20551942]
Endometrial cancer [NCBI:83109] [KEGG:hsa05213] [PUBMED:14747944] [PUBMED:11431710] [PUBMED:7585656] [PUBMED:16508724] [PUBMED:15284264] [PUBMED:17028294] [PUBMED:16248975] [PUBMED:15947972]
Epigenetic regulation of gene expression [NCBI:1269734] [REACTOME:R-HSA-212165] [PUBMED:12610534]
Epstein-Barr virus infection [NCBI:585562] [KEGG:hsa05169] [PUBMED:1658397] [PUBMED:10683340] [PUBMED:19375142] [PUBMED:12438576] [PUBMED:12910248] [PUBMED:10400785] [PUBMED:16007144] [PUBMED:14576817] [PUBMED:18559925] [PUBMED:16352731] [PUBMED:7895172] [PUBMED:15510157] [PUBMED:21518914] [PUBMED:10891508] [PUBMED:14673102] [PUBMED:17159145] [PUBMED:15542638] [PUBMED:18786993] [PUBMED:16603506] [PUBMED:10644367] [PUBMED:15021898] [PUBMED:10666279] [PUBMED:9565632]
ErbB signaling pathway [NCBI:83049] [KEGG:hsa04012] [PUBMED:16377102] [PUBMED:14967450] [PUBMED:9642287] [PUBMED:9872057] [PUBMED:10880430] [PUBMED:12851486] [PUBMED:16729045] [PUBMED:15863494] [PUBMED:15864276] [PUBMED:17000658] [PUBMED:16729043] [PUBMED:10490623] [PUBMED:11252954] [PUBMED:14744244] [PUBMED:16829981]
Fc epsilon receptor (FCERI) signaling [NCBI:1269298] [REACTOME:R-HSA-2454202] [PUBMED:15099567] [PUBMED:21799019]
Focal adhesion [NCBI:83067] [KEGG:hsa04510] [PUBMED:10698680] [PUBMED:15459662] [PUBMED:14756624] [PUBMED:11573199] [PUBMED:12640026] [PUBMED:15179030] [PUBMED:15108811] [PUBMED:15053919] [PUBMED:11082269] [PUBMED:15034601] [PUBMED:12235283] [PUBMED:14519391] [PUBMED:11146675] [PUBMED:11229600] [PUBMED:15688067] [PUBMED:14744429] [PUBMED:11882383]
GAB1 signalosome [NCBI:1269384] [REACTOME:R-HSA-180292] [PUBMED:15550174]
GLI3 is processed to GLI3R by the proteasome [NCBI:1269637] [REACTOME:R-HSA-5610785] [PUBMED:21921029] [PUBMED:20154143] [PUBMED:16371461] [PUBMED:10693759] [PUBMED:16705181] [PUBMED:17283082]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Glucocorticoid receptor regulatory network [NCBI:138014] [Pathway Interaction Database:reg_gr_pathway] [PUBMED:8943293] [PUBMED:1708774] [PUBMED:15826950] [PUBMED:11027313] [PUBMED:12118039] [PUBMED:9388207] [PUBMED:11751894] [PUBMED:12151000] [PUBMED:9765258] [PUBMED:9407028] [PUBMED:19074285] [PUBMED:2838908] [PUBMED:15817653] [PUBMED:9722596] [PUBMED:12917342] [PUBMED:1387550] [PUBMED:10974006] [PUBMED:15790729] [PUBMED:10825196] [PUBMED:10623828] [PUBMED:2169352] [PUBMED:9315653] [PUBMED:7759501] [PUBMED:8290595] [PUBMED:2905764] [PUBMED:12351702] [PUBMED:11080152] [PUBMED:8428574] [PUBMED:9215863] [PUBMED:15459252] [PUBMED:10400612] [PUBMED:9426156] [PUBMED:17440046] [PUBMED:18838540] [PUBMED:2169353] [PUBMED:10820245] [PUBMED:12511605] [PUBMED:2586521] [PUBMED:1740658] [PUBMED:11555652] [PUBMED:11562347] [PUBMED:9482836] [PUBMED:18337589] [PUBMED:10958685] [PUBMED:9388192] [PUBMED:15834420] [PUBMED:15657031] [PUBMED:8878484] [PUBMED:10760263] [PUBMED:12730237] [PUBMED:8702844] [PUBMED:2169351] [PUBMED:17215482] [PUBMED:8898375]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:17446673] [PUBMED:16436385] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:16155605] [PUBMED:16036567] [PUBMED:11244044] [PUBMED:18702816] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:16155611] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:10602469] [PUBMED:19014483] [PUBMED:9325311]
Hedgehog 'off' state [NCBI:1269636] [REACTOME:R-HSA-5610787] [PUBMED:21801010] [PUBMED:20395968] [PUBMED:23719536] [PUBMED:21502959]
Hedgehog signaling events mediated by Gli proteins [NCBI:137912] [Pathway Interaction Database:hedgehog_glipathway] [PUBMED:14611647] [PUBMED:16908539] [PUBMED:16885213] [PUBMED:16459297] [PUBMED:15087129] [PUBMED:10075717] [PUBMED:10725236] [PUBMED:10564661] [PUBMED:15215207] [PUBMED:16611981] [PUBMED:16364285] [PUBMED:11748151] [PUBMED:16537363] [PUBMED:10531011] [PUBMED:11449277] [PUBMED:12812795] [PUBMED:16424016] [PUBMED:14723851] [PUBMED:10693759] [PUBMED:15545630] [PUBMED:16254602] [PUBMED:14603322] [PUBMED:16061793] [PUBMED:10559945] [PUBMED:16740475] [PUBMED:16705181] [PUBMED:9636069] [PUBMED:10806483] [PUBMED:11960000] [PUBMED:15930098]
Hedgehog signaling pathway [NCBI:83063] [KEGG:hsa04340] [PUBMED:22534646] [PUBMED:26077918] [PUBMED:24925320] [PUBMED:23719536] [PUBMED:26064136] [PUBMED:26366162] [PUBMED:20708941] [PUBMED:22056910] [PUBMED:18583599] [PUBMED:23799571] [PUBMED:26875496]
Hepatitis C [NCBI:173973] [KEGG:hsa05160] [PUBMED:19708811] [PUBMED:16314558] [PUBMED:17467654] [PUBMED:19515018] [PUBMED:18514579] [PUBMED:16107833] [PUBMED:19074178] [PUBMED:12691459] [PUBMED:15302943] [PUBMED:20537953] [PUBMED:11991644] [PUBMED:19148799] [PUBMED:19187070] [PUBMED:12655344]
Hippo signaling pathway [NCBI:749777] [KEGG:hsa04390] [PUBMED:18955139] [PUBMED:20439427] [PUBMED:20951342] [PUBMED:21138973] [PUBMED:18328423] [PUBMED:21324984] [PUBMED:23034192] [PUBMED:21808241] [PUBMED:17975546] [PUBMED:22750148] [PUBMED:21084559] [PUBMED:19846288] [PUBMED:22895435] [PUBMED:22683405] [PUBMED:22658639] [PUBMED:22153608] [PUBMED:20945341] [PUBMED:22830020] [PUBMED:21874053] [PUBMED:21376238]
IL-17 signaling pathway [NCBI:1474301] [KEGG:hsa04657] [PUBMED:17921324] [PUBMED:24011563] [PUBMED:21349428] [PUBMED:20383173] [PUBMED:20514051] [PUBMED:20177959] [PUBMED:18178098] [PUBMED:21074482] [PUBMED:21130872] [PUBMED:17027518] [PUBMED:23917206] [PUBMED:23116200] [PUBMED:18701318] [PUBMED:26252407] [PUBMED:22851696] [PUBMED:21155836] [PUBMED:25145755] [PUBMED:17177681] [PUBMED:19575028] [PUBMED:23557798] [PUBMED:21852080] [PUBMED:22324470]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Influenza A [NCBI:217173] [KEGG:hsa05164] [PUBMED:17267598] [PUBMED:18049471] [PUBMED:16882036] [PUBMED:11907320] [PUBMED:17944269] [PUBMED:20629046] [PUBMED:17072332] [PUBMED:18588994] [PUBMED:19864182] [PUBMED:19290913] [PUBMED:19420020] [PUBMED:17213831] [PUBMED:9060654] [PUBMED:19481124] [PUBMED:16494716] [PUBMED:21147034] [PUBMED:18980544] [PUBMED:20020828] [PUBMED:15502848] [PUBMED:19782761]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Insulin resistance [NCBI:1272486] [KEGG:hsa04931] [PUBMED:17130651] [PUBMED:20466550] [PUBMED:16364488] [PUBMED:12765939] [PUBMED:15166380] [PUBMED:7666792] [PUBMED:16756496] [PUBMED:23647930] [PUBMED:10923637] [PUBMED:17141630] [PUBMED:9886945] [PUBMED:8048519] [PUBMED:18309108] [PUBMED:15107844] [PUBMED:20526383] [PUBMED:22360800] [PUBMED:16186396] [PUBMED:22675355] [PUBMED:22677645]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:11742412] [PUBMED:11343120] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:10567225] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:15624019] [PUBMED:9445476] [PUBMED:9346240] [PUBMED:14635525] [PUBMED:16288289] [PUBMED:12867054] [PUBMED:15229476] [PUBMED:17344645] [PUBMED:9609111]
Insulin-mediated glucose transport [NCBI:137981] [Pathway Interaction Database:insulin_glucose_pathway] [PUBMED:16880201] [PUBMED:9267469] [PUBMED:17059388] [PUBMED:2123524] [PUBMED:8392229] [PUBMED:9819385] [PUBMED:11001060] [PUBMED:10394363] [PUBMED:10869347] [PUBMED:11994271] [PUBMED:11997497] [PUBMED:11309621] [PUBMED:16213228] [PUBMED:15616009] [PUBMED:9582355] [PUBMED:15254270] [PUBMED:12637568] [PUBMED:8816781] [PUBMED:11102509] [PUBMED:16055084] [PUBMED:10364240] [PUBMED:9712142]
LKB1 signaling events [NCBI:137957] [Pathway Interaction Database:lkb1_pathway] [PUBMED:12429843] [PUBMED:18339622] [PUBMED:16912160] [PUBMED:15454081] [PUBMED:19513107] [PUBMED:16959574] [PUBMED:11741830] [PUBMED:7706316] [PUBMED:18063805] [PUBMED:14614828] [PUBMED:16306228] [PUBMED:12489981] [PUBMED:19386264] [PUBMED:18439900] [PUBMED:12805220] [PUBMED:17959818] [PUBMED:16396636] [PUBMED:10542369] [PUBMED:16308421] [PUBMED:15016379] [PUBMED:19622832] [PUBMED:14511394] [PUBMED:14676191] [PUBMED:17482548] [PUBMED:17991864] [PUBMED:11445556] [PUBMED:14651849] [PUBMED:14517248] [PUBMED:14985505] [PUBMED:15261145] [PUBMED:16817901] [PUBMED:9108484] [PUBMED:17573348] [PUBMED:12973359] [PUBMED:19369417] [PUBMED:15705853] [PUBMED:10642527] [PUBMED:16627617] [PUBMED:17482549] [PUBMED:8631898] [PUBMED:14976552]
LPA receptor mediated events [NCBI:137928] [Pathway Interaction Database:lysophospholipid_pathway] [PUBMED:10601262] [PUBMED:16289596] [PUBMED:7809106] [PUBMED:10342794] [PUBMED:15928312] [PUBMED:16769764] [PUBMED:11243883] [PUBMED:14688263] [PUBMED:10551845] [PUBMED:16687414] [PUBMED:9819398] [PUBMED:7527052] [PUBMED:9600933] [PUBMED:2551506] [PUBMED:15988003] [PUBMED:10644509] [PUBMED:16199135] [PUBMED:15728708] [PUBMED:1637305] [PUBMED:7476905] [PUBMED:7510708] [PUBMED:8647803] [PUBMED:10420989] [PUBMED:12880866] [PUBMED:10766839] [PUBMED:12181443] [PUBMED:15461590] [PUBMED:16452634] [PUBMED:16197369] [PUBMED:10779388] [PUBMED:10506190] [PUBMED:9305878] [PUBMED:16904289] [PUBMED:15878967] [PUBMED:15143197] [PUBMED:11948806] [PUBMED:11040035] [PUBMED:12393875] [PUBMED:9407095] [PUBMED:15280372] [PUBMED:16890224] [PUBMED:8805276]
Measles [NCBI:213306] [KEGG:hsa05162] [PUBMED:16237742] [PUBMED:12804771] [PUBMED:19198562] [PUBMED:20376484] [PUBMED:11385511] [PUBMED:16963735] [PUBMED:19198566] [PUBMED:18922877] [PUBMED:19203114] [PUBMED:12620806] [PUBMED:16690907] [PUBMED:17720800] [PUBMED:20636817] [PUBMED:12410527] [PUBMED:11582511] [PUBMED:19203109] [PUBMED:19203113] [PUBMED:14585342] [PUBMED:12805463]
Melanogenesis [NCBI:83092] [KEGG:hsa04916] [PUBMED:11041354] [PUBMED:10347209] [PUBMED:15016298] [PUBMED:11023702] [PUBMED:11602344] [PUBMED:12753399] [PUBMED:10841026] [PUBMED:16822996] [PUBMED:15383650] [PUBMED:9263329] [PUBMED:16246839] [PUBMED:10643996] [PUBMED:12894244]
Misspliced GSK3beta mutants stabilize beta-catenin [NCBI:1268921] [REACTOME:R-HSA-5339716] [PUBMED:15306667] [PUBMED:19237556]
NGF signalling via TRKA from the plasma membrane [NCBI:1269460] [REACTOME:R-HSA-187037] [PUBMED:11520933] [PUBMED:12676795] [PUBMED:10851172] [PUBMED:10579918]
Neurotrophin signaling pathway [NCBI:101143] [KEGG:hsa04722] [PUBMED:16699811] [PUBMED:10812966] [PUBMED:12676795] [PUBMED:16939974] [PUBMED:10851172] [PUBMED:15499580] [PUBMED:14704852] [PUBMED:11399424] [PUBMED:10764727] [PUBMED:10985348] [PUBMED:16856873] [PUBMED:11529497]
Non-alcoholic fatty liver disease (NAFLD) [NCBI:862188] [KEGG:hsa04932] [PUBMED:21038418] [PUBMED:17498512] [PUBMED:19352614] [PUBMED:23299992] [PUBMED:22570745] [PUBMED:9285483] [PUBMED:12891546] [PUBMED:18061659] [PUBMED:22705006] [PUBMED:16364488] [PUBMED:18242193] [PUBMED:16374858] [PUBMED:22940046] [PUBMED:20619513] [PUBMED:20303879] [PUBMED:14685853] [PUBMED:16406828] [PUBMED:23545492] [PUBMED:21145844]
PI3K-Akt signaling pathway [NCBI:692234] [KEGG:hsa04151] [PUBMED:12048182] [PUBMED:11357143] [PUBMED:21440011] [PUBMED:15209374] [PUBMED:12669022] [PUBMED:18842113] [PUBMED:16847462] [PUBMED:12660731] [PUBMED:17360849] [PUBMED:9838078] [PUBMED:15505410] [PUBMED:16248975] [PUBMED:12531180] [PUBMED:21779440] [PUBMED:16187290] [PUBMED:15784165] [PUBMED:21620960]
PI3K/AKT Signaling in Cancer [NCBI:1268879] [REACTOME:R-HSA-2219528] [PUBMED:20713702] [PUBMED:10555148] [PUBMED:19644473] [PUBMED:17611497] [PUBMED:21478295] [PUBMED:17626883] [PUBMED:16339315] [PUBMED:18317450] [PUBMED:18079394] [PUBMED:9467011] [PUBMED:17604717] [PUBMED:9326929] [PUBMED:18954143] [PUBMED:20009532] [PUBMED:19962665] [PUBMED:21430697] [PUBMED:19487573] [PUBMED:10866302]
PI3K/AKT activation [NCBI:1269473] [REACTOME:R-HSA-198203] [PUBMED:10579926] [PUBMED:12123609]
PIP3 activates AKT signaling [NCBI:1269188] [REACTOME:R-HSA-1257604]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Positive epigenetic regulation of rRNA expression [NCBI:1339125] [REACTOME:R-HSA-5250913] [PUBMED:23153826] [PUBMED:16574391] [PUBMED:23063748] [PUBMED:23150253] [PUBMED:18616426]
Presenilin action in Notch and Wnt signaling [NCBI:137914] [Pathway Interaction Database:ps1pathway] [PUBMED:10391247] [PUBMED:11921277] [PUBMED:11357136] [PUBMED:15620650] [PUBMED:11739397] [PUBMED:15747065] [PUBMED:10359821] [PUBMED:15327768] [PUBMED:12554650] [PUBMED:15292388] [PUBMED:11266469] [PUBMED:12794186] [PUBMED:10882062] [PUBMED:8923452] [PUBMED:12050670] [PUBMED:10201374] [PUBMED:12857724] [PUBMED:9171444]
Prolactin signaling pathway [NCBI:814182] [KEGG:hsa04917] [PUBMED:17519353] [PUBMED:17535875] [PUBMED:20149678] [PUBMED:12670737] [PUBMED:17307904] [PUBMED:18601698] [PUBMED:17975019] [PUBMED:16231422] [PUBMED:18219564] [PUBMED:9475379] [PUBMED:16677418] [PUBMED:9626554] [PUBMED:21664429] [PUBMED:11606470]
Prostate cancer [NCBI:83111] [KEGG:hsa05215] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11527574] [PUBMED:11750244] [PUBMED:16551847] [PUBMED:10835690] [PUBMED:8069858] [PUBMED:15724144] [PUBMED:10453277] [PUBMED:15082523] [PUBMED:9422516]
Reelin signaling pathway [NCBI:137980] [Pathway Interaction Database:reelinpathway] [PUBMED:12526739] [PUBMED:12899622] [PUBMED:14517291] [PUBMED:10939329] [PUBMED:16148228] [PUBMED:15062102] [PUBMED:15987942] [PUBMED:15091337] [PUBMED:12376533] [PUBMED:10827199] [PUBMED:12882964] [PUBMED:15590913] [PUBMED:14724251] [PUBMED:15361067] [PUBMED:14578885]
Regulation of Androgen receptor activity [NCBI:138027] [Pathway Interaction Database:ar_tf_pathway] [PUBMED:15650026] [PUBMED:17045208] [PUBMED:10364196] [PUBMED:16860317] [PUBMED:10611280] [PUBMED:10930412] [PUBMED:1525041] [PUBMED:10779504] [PUBMED:12514133] [PUBMED:1985913] [PUBMED:11931767] [PUBMED:17011549] [PUBMED:15640443] [PUBMED:16322096] [PUBMED:15923603] [PUBMED:14985354] [PUBMED:15743818] [PUBMED:12949936] [PUBMED:11994312] [PUBMED:10567371] [PUBMED:11875111] [PUBMED:15604291] [PUBMED:12890669] [PUBMED:14729952] [PUBMED:9211894] [PUBMED:9162033] [PUBMED:16705743] [PUBMED:16849544] [PUBMED:16923962] [PUBMED:11591700] [PUBMED:16051670] [PUBMED:8643509] [PUBMED:17108144] [PUBMED:16914734] [PUBMED:12682292] [PUBMED:3353726] [PUBMED:11585838] [PUBMED:16282370] [PUBMED:10381882] [PUBMED:15199155] [PUBMED:16455820] [PUBMED:14612401] [PUBMED:10625666] [PUBMED:17679089] [PUBMED:16461774]
Regulation of HSF1-mediated heat shock response [NCBI:1270425] [REACTOME:R-HSA-3371453] [PUBMED:7623826]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
Role of LAT2/NTAL/LAB on calcium mobilization [NCBI:1269302] [REACTOME:R-HSA-2730905] [PUBMED:17993265] [PUBMED:20643813] [PUBMED:17420272]
S33 mutants of beta-catenin aren't phosphorylated [NCBI:1268920] [REACTOME:R-HSA-5358747] [PUBMED:10487827] [PUBMED:12067995] [PUBMED:10921899] [PUBMED:18757411]
S37 mutants of beta-catenin aren't phosphorylated [NCBI:1268919] [REACTOME:R-HSA-5358749] [PUBMED:10487827] [PUBMED:12067995] [PUBMED:10921899]
S45 mutants of beta-catenin aren't phosphorylated [NCBI:1268917] [REACTOME:R-HSA-5358751] [PUBMED:9065402] [PUBMED:12000790] [PUBMED:10921899]
Semaphorin interactions [NCBI:1270304] [REACTOME:R-HSA-373755] [PUBMED:12593985] [PUBMED:12471249] [PUBMED:18269210] [PUBMED:16939971] [PUBMED:18374575]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by EGFR [NCBI:1269380] [REACTOME:R-HSA-177929] [PUBMED:10459005] [PUBMED:10404636] [PUBMED:12297041] [PUBMED:15142631]
Signaling by Hedgehog [NCBI:1269633] [REACTOME:R-HSA-5358351] [PUBMED:19081070] [PUBMED:21801010] [PUBMED:15549094] [PUBMED:23719536]
Signaling by PDGF [NCBI:1269478] [REACTOME:R-HSA-186797] [PUBMED:15207811] [PUBMED:10508235] [PUBMED:9739761]
Signaling by SCF-KIT [NCBI:1269487] [REACTOME:R-HSA-1433557] [PUBMED:17350321] [PUBMED:16483568] [PUBMED:7688988] [PUBMED:19540337] [PUBMED:16475976] [PUBMED:15526160]
Signaling by WNT in cancer [NCBI:1268906] [REACTOME:R-HSA-4791275] [PUBMED:7749328] [PUBMED:6318122] [PUBMED:22438566] [PUBMED:17510365] [PUBMED:10700176] [PUBMED:10733430] [PUBMED:17143297] [PUBMED:18311776] [PUBMED:11375957]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
Signaling by the B Cell Receptor (BCR) [NCBI:1269183] [REACTOME:R-HSA-983705] [PUBMED:1702903] [PUBMED:2011584] [PUBMED:1081164] [PUBMED:19065780] [PUBMED:16849466] [PUBMED:1375264] [PUBMED:7538118] [PUBMED:11901194] [PUBMED:8580068] [PUBMED:19249086] [PUBMED:18596693] [PUBMED:10648173] [PUBMED:4589993] [PUBMED:8163536] [PUBMED:1376928] [PUBMED:7688784] [PUBMED:6335036] [PUBMED:17052215] [PUBMED:18818202] [PUBMED:20206686] [PUBMED:7592958] [PUBMED:7524079] [PUBMED:15489917] [PUBMED:15509800] [PUBMED:18187424] [PUBMED:7927516] [PUBMED:803528] [PUBMED:19909372] [PUBMED:20192804] [PUBMED:8306975]
Signaling events mediated by Stem cell factor receptor (c-Kit) [NCBI:138068] [Pathway Interaction Database:kitpathway] [PUBMED:12909618] [PUBMED:10364466] [PUBMED:10673502] [PUBMED:15315962] [PUBMED:12192036] [PUBMED:12444928] [PUBMED:15504549] [PUBMED:8950973] [PUBMED:11071635] [PUBMED:12149208] [PUBMED:11369651] [PUBMED:9038210] [PUBMED:10679268] [PUBMED:15465815] [PUBMED:10523831] [PUBMED:8611693] [PUBMED:15676208] [PUBMED:11805142] [PUBMED:10637471] [PUBMED:9872323] [PUBMED:11809791] [PUBMED:11520784] [PUBMED:12691919] [PUBMED:10397721] [PUBMED:15611091] [PUBMED:12356726] [PUBMED:9528781] [PUBMED:1381360] [PUBMED:9651683] [PUBMED:10849422] [PUBMED:9355737]
Signaling pathways regulating pluripotency of stem cells [NCBI:1026136] [KEGG:hsa04550] [PUBMED:20705693] [PUBMED:23653415] [PUBMED:16518401] [PUBMED:17211451] [PUBMED:22649650] [PUBMED:24910449] [PUBMED:19551525] [PUBMED:22298652] [PUBMED:23370346] [PUBMED:24315442] [PUBMED:18414030] [PUBMED:17647265] [PUBMED:18295576] [PUBMED:24957798] [PUBMED:24147644] [PUBMED:16153702] [PUBMED:19427042] [PUBMED:18220859] [PUBMED:19571885] [PUBMED:23585347]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
T cell receptor signaling pathway [NCBI:83080] [KEGG:hsa04660] [PUBMED:17395537] [PUBMED:15308211] [PUBMED:15928679] [PUBMED:14656980] [PUBMED:17187070] [PUBMED:15084594] [PUBMED:16799472] [PUBMED:12669022] [PUBMED:15286727] [PUBMED:15122199] [PUBMED:19132916] [PUBMED:15489916] [PUBMED:11905831] [PUBMED:12195013] [PUBMED:15343367] [PUBMED:12133805] [PUBMED:14647476] [PUBMED:15771581] [PUBMED:15099566] [PUBMED:14617194] [PUBMED:19290929] [PUBMED:15345216]
T41 mutants of beta-catenin aren't phosphorylated [NCBI:1268918] [REACTOME:R-HSA-5358752] [PUBMED:12101426] [PUBMED:12439748] [PUBMED:22438566] [PUBMED:10921899] [PUBMED:23256519]
TCF dependent signaling in response to WNT [NCBI:1269599] [REACTOME:R-HSA-201681] [PUBMED:19619488] [PUBMED:23256519] [PUBMED:23343194]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:20005976] [PUBMED:17983645] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:16214361] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:16051672] [PUBMED:19295177] [PUBMED:23021374] [PUBMED:22484490]
Trk receptor signaling mediated by PI3K and PLC-gamma [NCBI:137967] [Pathway Interaction Database:pi3kplctrkpathway] [PUBMED:11136977] [PUBMED:11864996] [PUBMED:8663990] [PUBMED:12367511] [PUBMED:9094314] [PUBMED:10330161] [PUBMED:11953455] [PUBMED:7886457] [PUBMED:16319926] [PUBMED:10102273] [PUBMED:11418861] [PUBMED:10729337] [PUBMED:9346240] [PUBMED:10677043] [PUBMED:15702476] [PUBMED:15207235] [PUBMED:9637919]
Truncations of AMER1 destabilize the destruction complex [NCBI:1268915] [REACTOME:R-HSA-5467348] [PUBMED:19760609] [PUBMED:18311776] [PUBMED:17510365] [PUBMED:21248786]
Wnt signaling pathway [NCBI:83061] [KEGG:hsa04310] [PUBMED:12446114] [PUBMED:14745971] [PUBMED:14530294] [PUBMED:15102436] [PUBMED:14635791] [PUBMED:19482104] [PUBMED:23256519] [PUBMED:12967557] [PUBMED:11433294] [PUBMED:18838381]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:17277771] [PUBMED:15341740] [PUBMED:12172553] [PUBMED:15718470] [PUBMED:14651849] [PUBMED:15268862] [PUBMED:15306821] [PUBMED:26046644] [PUBMED:12869586] [PUBMED:24556838] [PUBMED:17928295] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:26658722] [PUBMED:24842496] [PUBMED:23465396] [PUBMED:17709744] [PUBMED:17599906] [PUBMED:16919458] [PUBMED:10364159] [PUBMED:15342917] [PUBMED:11500364] [PUBMED:19812304] [PUBMED:12482958] [PUBMED:11729323] [PUBMED:16962653] [PUBMED:18952604] [PUBMED:9465032] [PUBMED:1496022] [PUBMED:10567431] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:18604198] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:17461779] [PUBMED:9445476] [PUBMED:18497260] [PUBMED:12604610] [PUBMED:15071500] [PUBMED:18925875] [PUBMED:12906785] [PUBMED:11287630] [PUBMED:15004009] [PUBMED:16756488] [PUBMED:17043309] [PUBMED:18198340] [PUBMED:12820960] [PUBMED:12747827] [PUBMED:17053147] [PUBMED:15851026] [PUBMED:15467718] [PUBMED:18762023] [PUBMED:25242279] [PUBMED:24698685] [PUBMED:11175345] [PUBMED:27304501] [PUBMED:18411301] [PUBMED:11500365] [PUBMED:17693255] [PUBMED:23694989] [PUBMED:12231510] [PUBMED:19446321] [PUBMED:11418588] [PUBMED:19258318] [PUBMED:18439900] [PUBMED:19225151] [PUBMED:26185979] [PUBMED:10357815] [PUBMED:26269525] [PUBMED:23421405] [PUBMED:9271440] [PUBMED:16915281] [PUBMED:17141160] [PUBMED:15249583] [PUBMED:12912989] [PUBMED:27027448] [PUBMED:18423201] [PUBMED:19211835] [PUBMED:9204908] [PUBMED:26700098] [PUBMED:18566587] [PUBMED:17386266]
p53 pathway [NCBI:138067] [Pathway Interaction Database:p53regulationpathway] [PUBMED:9153395] [PUBMED:15448695] [PUBMED:10734067] [PUBMED:11340074] [PUBMED:15525938] [PUBMED:17189186] [PUBMED:18454141] [PUBMED:11715018] [PUBMED:9733514] [PUBMED:12963717] [PUBMED:15989956] [PUBMED:10581258] [PUBMED:18566590] [PUBMED:15029243] [PUBMED:14612427] [PUBMED:19011621] [PUBMED:12842086] [PUBMED:16377624] [PUBMED:17268548] [PUBMED:16845383] [PUBMED:17534149] [PUBMED:12397361] [PUBMED:11740489] [PUBMED:12110584] [PUBMED:11713287] [PUBMED:17646389] [PUBMED:14654783] [PUBMED:9153396] [PUBMED:18243116] [PUBMED:10673501] [PUBMED:17719542] [PUBMED:11983168] [PUBMED:12397362] [PUBMED:17189187] [PUBMED:16757976] [PUBMED:12667443] [PUBMED:9733515] [PUBMED:9878046] [PUBMED:9363941] [PUBMED:11504915] [PUBMED:11359766] [PUBMED:9529248] [PUBMED:17936559] [PUBMED:15210108] [PUBMED:17293853] [PUBMED:16107876] [PUBMED:9724636] [PUBMED:17707234] [PUBMED:10606744] [PUBMED:11780126] [PUBMED:10821866] [PUBMED:18485870] [PUBMED:17110336] [PUBMED:11046142] [PUBMED:11331603] [PUBMED:19597489] [PUBMED:16163388] [PUBMED:14671306] [PUBMED:17108971] [PUBMED:15242646] [PUBMED:15314173] [PUBMED:12654245] [PUBMED:15308643] [PUBMED:9744860] [PUBMED:17906639] [PUBMED:9891054] [PUBMED:17098746] [PUBMED:17349958] [PUBMED:11030628] [PUBMED:15103385] [PUBMED:14744935] [PUBMED:9529249] [PUBMED:11283254] [PUBMED:11606419] [PUBMED:11078726] [PUBMED:10611322] [PUBMED:9288740] [PUBMED:11127820] [PUBMED:19357310] [PUBMED:9450543]
phosphorylation site mutants of CTNNB1 are not targeted to the proteasome by the destruction complex [NCBI:1268916] [REACTOME:R-HSA-4839743] [PUBMED:9601641] [PUBMED:10733430] [PUBMED:9065402] [PUBMED:23256519] [PUBMED:11375957] [PUBMED:9065403]
truncated APC mutants destabilize the destruction complex [NCBI:1268907] [REACTOME:R-HSA-4839744] [PUBMED:1338904] [PUBMED:8756721] [PUBMED:9065402] [PUBMED:17143297] [PUBMED:23256519] [PUBMED:8111410] [PUBMED:23169527] [PUBMED:15327768] [PUBMED:22761442] [PUBMED:10921899] [PUBMED:9065401]