full name
calcium sensing receptor

synonyms
CAR, EIG8, FHH, FIH, GPRC2A, HHC, HHC1, NSHPT, PCAR1, CASR, ENSG00000036828

HGNC
HGNC:1514

Entrez Gene
Gene:846

ENSEMBL
ENSG00000036828

location
chr: 3
start: 121902530
stop: 122005350
strand: +

OMIM
OMIM:601199: CASR
OMIM:239200: Hyperparathyroidism, neonatal
OMIM:601198: Hypocalcemia, autosomal dominant
OMIM:601198: Hypocalcemia, autosomal dominant, with Bartter syndrome
OMIM:145980: Hypocalciuric hypercalcemia, type I
OMIM:612899: {Epilepsy idiopathic generalized, susceptibility to, 8}

transcripts
ENST00000490131.1
ENST00000498619.1

pathways
Class C/3 (Metabotropic glutamate/pheromone receptors) [NCBI:1269573] [REACTOME:R-HSA-420499] [PUBMED:12782243] [PUBMED:17266540]
E-cadherin signaling in keratinocytes [NCBI:138002] [Pathway Interaction Database:ecadherin_keratinocyte_pathway] [PUBMED:16036919] [PUBMED:17439945] [PUBMED:10969083] [PUBMED:15872086] [PUBMED:17124506] [PUBMED:10660044] [PUBMED:8063817] [PUBMED:18754040] [PUBMED:19158393] [PUBMED:9628900] [PUBMED:12652652] [PUBMED:14647292] [PUBMED:12147707] [PUBMED:18065418] [PUBMED:17242406] [PUBMED:12782654] [PUBMED:12417594] [PUBMED:11777936]
G alpha (i) signalling events [NCBI:1269576] [REACTOME:R-HSA-418594] [PUBMED:3113327] [PUBMED:9278091]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
NOD-like receptor signaling pathway [NCBI:122191] [KEGG:hsa04621] [PUBMED:25330206] [PUBMED:21575908] [PUBMED:23846113] [PUBMED:26549800] [PUBMED:16493424] [PUBMED:23124073] [PUBMED:24840700] [PUBMED:27291964] [PUBMED:27012466] [PUBMED:24707857] [PUBMED:19767725] [PUBMED:25879280] [PUBMED:23215645] [PUBMED:22819539] [PUBMED:23702978] [PUBMED:20643110] [PUBMED:25879288] [PUBMED:26655628] [PUBMED:25145756] [PUBMED:24718315] [PUBMED:26482951] [PUBMED:25526305] [PUBMED:26121197] [PUBMED:22430786]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]