full name
kalirin RhoGEF kinase
synonyms
ARHGEF24, CHD5, CHDS5, DUET, DUO, HAPIP, TRAD, KALRN, ENSG00000160145
HGNC
HGNC:4814
Entrez Gene
Gene:8997
ENSEMBL
ENSG00000160145
location
chr: 3
start: 123813558
stop: 124440036
strand: +
OMIM
OMIM:604605:
KALRN
OMIM:608901:
{Coronary heart disease, susceptibility to, 5}
transcripts
NM_001024660.3
NM_003947.4
NR_028136.1
NM_007064.3
pathways
Arf6 downstream pathway
[NCBI:138038]
[Pathway Interaction Database:arf6downstreampathway]
[PUBMED:12388770]
[PUBMED:14565977]
[PUBMED:10036235]
[PUBMED:14764880]
[PUBMED:12447393]
[PUBMED:9312003]
[PUBMED:17077126]
[PUBMED:17363898]
[PUBMED:14505574]
[PUBMED:16280360]
[PUBMED:17628206]
[PUBMED:15601896]
[PUBMED:10913182]
[PUBMED:16452216]
[PUBMED:7753201]
[PUBMED:15210957]
[PUBMED:16880525]
[PUBMED:16181626]
[PUBMED:17640372]
[PUBMED:11481345]
[PUBMED:17409355]
[PUBMED:12379803]
[PUBMED:18084281]
[PUBMED:10589680]
[PUBMED:11532961]
[PUBMED:17353194]
[PUBMED:8769418]
[PUBMED:10779358]
[PUBMED:18026091]
[PUBMED:12509462]
[PUBMED:15087504]
[PUBMED:9664047]
Axon guidance
[NCBI:83065]
[KEGG:hsa04360]
[NCBI:1270303]
[REACTOME:R-HSA-422475]
[PUBMED:14682358]
[PUBMED:15084255]
[PUBMED:11687826]
[PUBMED:15818466]
[PUBMED:15363605]
[PUBMED:12471249]
[PUBMED:15630019]
[PUBMED:11891122]
[PUBMED:15960985]
[PUBMED:12677003]
Cell death signalling via NRAGE, NRIF and NADE
[NCBI:1269447]
[REACTOME:R-HSA-204998]
[PUBMED:12787561]
Developmental Biology
[NCBI:1270302]
[REACTOME:R-HSA-1266738]
EPH-Ephrin signaling
[NCBI:1270330]
[REACTOME:R-HSA-2682334]
[PUBMED:18281458]
[PUBMED:22120527]
EPHB forward signaling
[NCBI:138047]
[Pathway Interaction Database:ephbfwdpathway]
[PUBMED:8808709]
[PUBMED:11780069]
[PUBMED:11585923]
[PUBMED:10644995]
[PUBMED:12223469]
[PUBMED:15351694]
[PUBMED:12973357]
[PUBMED:15107421]
[PUBMED:9233798]
[PUBMED:7973638]
[PUBMED:12389031]
[PUBMED:15536074]
[PUBMED:8755474]
[PUBMED:9430661]
[PUBMED:12546821]
[PUBMED:15107857]
[PUBMED:14500293]
[PUBMED:12925710]
[PUBMED:8878483]
[PUBMED:8918835]
[PUBMED:10669731]
[PUBMED:10570155]
[PUBMED:8761303]
[PUBMED:12408869]
[PUBMED:15821731]
[PUBMED:12475948]
EPHB-mediated forward signaling
[NCBI:1270332]
[REACTOME:R-HSA-3928662]
[PUBMED:12808016]
G alpha (12/13) signalling events
[NCBI:1269579]
[REACTOME:R-HSA-416482]
[PUBMED:18814923]
[PUBMED:19212140]
G alpha (q) signalling events
[NCBI:1269578]
[REACTOME:R-HSA-416476]
[PUBMED:19212139]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
MAPK family signaling cascades
[NCBI:1269501]
[REACTOME:R-HSA-5683057]
[PUBMED:21167873]
[PUBMED:17161475]
[PUBMED:22535895]
[PUBMED:21372320]
MAPK6/MAPK4 signaling
[NCBI:1269506]
[REACTOME:R-HSA-5687128]
[PUBMED:18644862]
[PUBMED:22800433]
[PUBMED:19166925]
[PUBMED:12808096]
[PUBMED:18248330]
[PUBMED:20849292]
[PUBMED:21329875]
[PUBMED:21177870]
[PUBMED:17161475]
[PUBMED:18593949]
[PUBMED:21372320]
[PUBMED:18720373]
[PUBMED:17947239]
[PUBMED:15226418]
[PUBMED:22505454]
NRAGE signals death through JNK
[NCBI:1269448]
[REACTOME:R-HSA-193648]
[PUBMED:12376548]
Regulation of RAC1 activity
[NCBI:169346]
[Pathway Interaction Database:rac1_reg_pathway]
[PUBMED:8297393]
[PUBMED:12134164]
[PUBMED:15485841]
[PUBMED:11707441]
[PUBMED:17320046]
[PUBMED:9857026]
[PUBMED:9497316]
[PUBMED:17254573]
[PUBMED:15850775]
[PUBMED:8352776]
[PUBMED:15128856]
[PUBMED:17403664]
[PUBMED:8491184]
[PUBMED:7753201]
[PUBMED:9707409]
[PUBMED:12432077]
[PUBMED:8226937]
[PUBMED:19934221]
[PUBMED:17196961]
[PUBMED:17640372]
[PUBMED:11287617]
[PUBMED:12515821]
[PUBMED:16943182]
[PUBMED:19861492]
[PUBMED:10220378]
[PUBMED:11431473]
[PUBMED:10982832]
[PUBMED:7673236]
[PUBMED:10744696]
[PUBMED:17599059]
[PUBMED:17116687]
[PUBMED:12923183]
[PUBMED:10364228]
[PUBMED:16628218]
[PUBMED:8288572]
[PUBMED:15306850]
[PUBMED:11396949]
[PUBMED:8496137]
[PUBMED:11912491]
[PUBMED:15649357]
[PUBMED:7980444]
[PUBMED:18325335]
[PUBMED:15242348]
[PUBMED:11955434]
[PUBMED:15039778]
[PUBMED:11685227]
[PUBMED:15897194]
[PUBMED:11130063]
[PUBMED:10559863]
[PUBMED:17052214]
[PUBMED:11099046]
[PUBMED:15728722]
[PUBMED:16520382]
[PUBMED:16492808]
[PUBMED:12547822]
[PUBMED:12446789]
[PUBMED:11274357]
[PUBMED:8419353]
[PUBMED:16481401]
[PUBMED:8276860]
[PUBMED:15005707]
[PUBMED:10499589]
[PUBMED:11336673]
[PUBMED:1903516]
[PUBMED:12829596]
[PUBMED:17332503]
[PUBMED:11146652]
[PUBMED:12134158]
[PUBMED:8643598]
[PUBMED:18212043]
Rho GTPase cycle
[NCBI:1269508]
[REACTOME:R-HSA-194840]
[PUBMED:17222083]
[PUBMED:9308960]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Signaling by Rho GTPases
[NCBI:1269507]
[REACTOME:R-HSA-194315]
[PUBMED:16212495]
[PUBMED:15630019]
Signalling by NGF
[NCBI:1269443]
[REACTOME:R-HSA-166520]
p75 NTR receptor-mediated signalling
[NCBI:1269445]
[REACTOME:R-HSA-193704]
[PUBMED:16699811]
[PUBMED:16939974]
[PUBMED:12671646]
