full name
RuvB like AAA ATPase 1

synonyms
ECP54, INO80H, NMP238, PONTIN, Pontin52, RVB1, TIH1, TIP49, TIP49A, RUVBL1, ENSG00000175792

HGNC
HGNC:10474

Entrez Gene
Gene:8607

ENSEMBL
ENSG00000175792

location
chr: 3
start: 127799800
stop: 127872752
strand: -

transcripts
NM_003707.2

pathways
C-MYC pathway [NCBI:169344] [Pathway Interaction Database:myc_pathway] [PUBMED:17558397] [PUBMED:10611234] [PUBMED:14563837] [PUBMED:12660246] [PUBMED:11018017] [PUBMED:12769844] [PUBMED:11445536] [PUBMED:17967894] [PUBMED:15199070] [PUBMED:17146439] [PUBMED:9708738] [PUBMED:20008325] [PUBMED:19131971] [PUBMED:12177005] [PUBMED:15048125] [PUBMED:15361884] [PUBMED:14749374] [PUBMED:15150404] [PUBMED:15103331] [PUBMED:12776177] [PUBMED:11673469] [PUBMED:9312026] [PUBMED:17597761] [PUBMED:12769843] [PUBMED:9927431] [PUBMED:10882073] [PUBMED:16537924]
Cell Cycle [NCBI:1269741] [REACTOME:R-HSA-1640170]
Chromatin modifying enzymes [NCBI:1270434] [REACTOME:R-HSA-3247509]
Chromatin organization [NCBI:1270433] [REACTOME:R-HSA-4839726] [PUBMED:21342762] [PUBMED:15598472]
Chromosome Maintenance [NCBI:1269853] [REACTOME:R-HSA-73886]
DNA Damage Recognition in GG-NER [NCBI:1309113] [REACTOME:R-HSA-5696394] [PUBMED:15811629] [PUBMED:12944386] [PUBMED:21388382] [PUBMED:14742321] [PUBMED:19609301]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Deposition of new CENPA-containing nucleosomes at the centromere [NCBI:1269855] [REACTOME:R-HSA-606279] [PUBMED:20080577] [PUBMED:19410545] [PUBMED:19629040] [PUBMED:19410544] [PUBMED:19660450] [PUBMED:19590885] [PUBMED:19410539] [PUBMED:17339380]
Deubiquitination [NCBI:1427860] [REACTOME:R-HSA-5688426] [PUBMED:19243136] [PUBMED:20074029] [PUBMED:15571815] [PUBMED:20418328] [PUBMED:16325574] [PUBMED:12944365] [PUBMED:23845989] [PUBMED:22201797]
Extension of Telomeres [NCBI:1269857] [REACTOME:R-HSA-180786] [PUBMED:15189140]
Formation of the beta-catenin:TCF transactivating complex [NCBI:1269602] [REACTOME:R-HSA-201722] [PUBMED:19305417] [PUBMED:11713476] [PUBMED:18334222] [PUBMED:11934263] [PUBMED:16751178] [PUBMED:22617422] [PUBMED:20951344] [PUBMED:11136974] [PUBMED:19619488] [PUBMED:10831834] [PUBMED:21285352]
Global Genome Nucleotide Excision Repair (GG-NER) [NCBI:1309112] [REACTOME:R-HSA-5696399] [PUBMED:24954209]
HATs acetylate histones [NCBI:1270435] [REACTOME:R-HSA-3214847] [PUBMED:18722564]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Nucleosome assembly [NCBI:1269854] [REACTOME:R-HSA-774815]
Nucleotide Excision Repair [NCBI:1309111] [REACTOME:R-HSA-5696398] [PUBMED:11900249] [PUBMED:23906714] [PUBMED:14599765] [PUBMED:10583946] [PUBMED:24954209] [PUBMED:19023283]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Wnt [NCBI:1269594] [REACTOME:R-HSA-195721] [PUBMED:19530173] [PUBMED:23256519] [PUBMED:22952392] [PUBMED:19204114] [PUBMED:19365405] [PUBMED:19619488] [PUBMED:17143292] [PUBMED:17230199] [PUBMED:18710302] [PUBMED:16099039] [PUBMED:20576942] [PUBMED:10858654] [PUBMED:12967557]
TCF dependent signaling in response to WNT [NCBI:1269599] [REACTOME:R-HSA-201681] [PUBMED:19619488] [PUBMED:23256519] [PUBMED:23343194]
Telomere Extension By Telomerase [NCBI:1269858] [REACTOME:R-HSA-171319] [PUBMED:14685173] [PUBMED:15189140]
Telomere Maintenance [NCBI:1269856] [REACTOME:R-HSA-157579] [PUBMED:16166375] [PUBMED:4507727] [PUBMED:14685173] [PUBMED:642006] [PUBMED:15189140] [PUBMED:3907856] [PUBMED:2463488] [PUBMED:4754905]
UCH proteinases [NCBI:1427861] [REACTOME:R-HSA-5689603] [PUBMED:16325574] [PUBMED:19243136]
Ub-specific processing proteases [NCBI:1427862] [REACTOME:R-HSA-5689880] [PUBMED:16325574]
Validated targets of C-MYC transcriptional activation [NCBI:169351] [Pathway Interaction Database:myc_activpathway] [PUBMED:18987359] [PUBMED:16537449] [PUBMED:9924025] [PUBMED:17643117] [PUBMED:8356088] [PUBMED:10688915] [PUBMED:1562593] [PUBMED:19020761] [PUBMED:10823814] [PUBMED:12637527] [PUBMED:9178906] [PUBMED:17967894] [PUBMED:15723053] [PUBMED:16508012] [PUBMED:8700224] [PUBMED:12091391] [PUBMED:20173740] [PUBMED:11522645] [PUBMED:15774466] [PUBMED:12776737] [PUBMED:12011429] [PUBMED:12138190] [PUBMED:10022128] [PUBMED:11511539] [PUBMED:12177005] [PUBMED:17599065] [PUBMED:6438521] [PUBMED:19745813] [PUBMED:8196628] [PUBMED:10891489] [PUBMED:8934531] [PUBMED:15723054] [PUBMED:9192621] [PUBMED:18042711] [PUBMED:10779353] [PUBMED:1989881] [PUBMED:8861962] [PUBMED:12529648] [PUBMED:16269333] [PUBMED:16172399] [PUBMED:8494784] [PUBMED:15282543] [PUBMED:8297793] [PUBMED:12776177] [PUBMED:9811896] [PUBMED:11103792] [PUBMED:17170079] [PUBMED:18593934] [PUBMED:11673469] [PUBMED:18408012] [PUBMED:1340466] [PUBMED:17088530] [PUBMED:8327497] [PUBMED:16423995] [PUBMED:12816956] [PUBMED:11598121] [PUBMED:14724288] [PUBMED:17848523] [PUBMED:10508165] [PUBMED:12695333] [PUBMED:17822678] [PUBMED:10606642] [PUBMED:9869632] [PUBMED:9212167] [PUBMED:19211792] [PUBMED:16287840] [PUBMED:18978814] [PUBMED:11511535] [PUBMED:15944709] [PUBMED:11604407] [PUBMED:11909865]
Wnt signaling pathway [NCBI:83061] [KEGG:hsa04310] [PUBMED:12446114] [PUBMED:14745971] [PUBMED:14530294] [PUBMED:15102436] [PUBMED:14635791] [PUBMED:19482104] [PUBMED:23256519] [PUBMED:12967557] [PUBMED:11433294] [PUBMED:18838381]