full name
RAB7A, member RAS oncogene family

synonyms
PRO2706, RAB7, RAB7A, ENSG00000075785

HGNC
HGNC:9788

Entrez Gene
Gene:7879

ENSEMBL
ENSG00000075785

location
chr: 3
start: 128444975
stop: 128533641
strand: +

OMIM
OMIM:602298: RAB7A (Autosomal dominant inheritance)
OMIM:600882: Charcot-Marie-Tooth disease, type 2B

transcripts
NM_004637.5

pathways
Adaptive Immune System [NCBI:1269171] [REACTOME:R-HSA-1280218] [PUBMED:16551257] [PUBMED:21682741] [PUBMED:11861602]
Amoebiasis [NCBI:167324] [KEGG:hsa05146] [PUBMED:9832261] [PUBMED:16380324] [PUBMED:14700586] [PUBMED:18725798] [PUBMED:12142490] [PUBMED:10637584] [PUBMED:20145703] [PUBMED:11378035] [PUBMED:12160867] [PUBMED:15813717] [PUBMED:19207103] [PUBMED:12660071] [PUBMED:20303955] [PUBMED:11352795] [PUBMED:14502002] [PUBMED:10756002] [PUBMED:17702556] [PUBMED:17576362]
Autophagy - animal [NCBI:83058] [KEGG:hsa04140] [PUBMED:16200202] [PUBMED:15325588] [PUBMED:24343578] [PUBMED:15978794] [PUBMED:19802558] [PUBMED:16099218] [PUBMED:11099404] [PUBMED:19653858] [PUBMED:15325584] [PUBMED:20034776] [PUBMED:15928708] [PUBMED:21801009] [PUBMED:25948417] [PUBMED:16125113] [PUBMED:21187343]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
IL12-mediated signaling events [NCBI:137922] [Pathway Interaction Database:il12_2pathway] [PUBMED:12874225] [PUBMED:12221108] [PUBMED:16380506] [PUBMED:9768751] [PUBMED:17114419] [PUBMED:10358173] [PUBMED:9890938] [PUBMED:12213961] [PUBMED:11120802] [PUBMED:9202126] [PUBMED:16641133] [PUBMED:10198225] [PUBMED:16763563] [PUBMED:15728489] [PUBMED:8103068] [PUBMED:10903740] [PUBMED:10201984] [PUBMED:7638186] [PUBMED:11894097] [PUBMED:16220539] [PUBMED:10961885] [PUBMED:7594594] [PUBMED:17110450] [PUBMED:9582275] [PUBMED:10320373] [PUBMED:7528775] [PUBMED:11207258] [PUBMED:9038232] [PUBMED:15522880] [PUBMED:11175814] [PUBMED:9531298] [PUBMED:7722452] [PUBMED:8943050] [PUBMED:7553885] [PUBMED:9454765]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
MHC class II antigen presentation [NCBI:1269200] [REACTOME:R-HSA-2132295] [PUBMED:19703008] [PUBMED:9316394] [PUBMED:11684289] [PUBMED:19217269] [PUBMED:8689559]
Membrane Trafficking [NCBI:1269877] [REACTOME:R-HSA-199991] [PUBMED:11031247]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Mitophagy - animal [NCBI:1496831] [KEGG:hsa04137] [PUBMED:26611876] [PUBMED:27443527] [PUBMED:25995186] [PUBMED:25611507] [PUBMED:27021519] [PUBMED:25999423] [PUBMED:27701735] [PUBMED:26882551]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Phagosome [NCBI:153910] [KEGG:hsa04145] [PUBMED:17637737] [PUBMED:18513324] [PUBMED:15894272] [PUBMED:10684585] [PUBMED:18492791] [PUBMED:15036145] [PUBMED:17245426]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
RAB GEFs exchange GTP for GDP on RABs [NCBI:1457806] [REACTOME:R-HSA-8876198] [PUBMED:23898197] [PUBMED:16855591] [PUBMED:22694141] [PUBMED:19603039] [PUBMED:7957092] [PUBMED:23303910] [PUBMED:7991565] [PUBMED:25402849] [PUBMED:8631982] [PUBMED:21330364] [PUBMED:8349690] [PUBMED:18532927] [PUBMED:20512138] [PUBMED:8662963] [PUBMED:21250943] [PUBMED:20466531] [PUBMED:25341920] [PUBMED:22251903] [PUBMED:8164745] [PUBMED:1944536] [PUBMED:14574414] [PUBMED:27246931]
RAB geranylgeranylation [NCBI:1470928] [REACTOME:R-HSA-8873719] [PUBMED:16855591] [PUBMED:1944536] [PUBMED:22065758] [PUBMED:8164745] [PUBMED:14574414] [PUBMED:23898197] [PUBMED:22251903] [PUBMED:25341920] [PUBMED:8662963] [PUBMED:7957092] [PUBMED:19603039] [PUBMED:22694141] [PUBMED:7991565] [PUBMED:20937701] [PUBMED:25402849] [PUBMED:18532927] [PUBMED:20512138] [PUBMED:8349690] [PUBMED:8631982]
Salmonella infection [NCBI:375172] [KEGG:hsa05132] [PUBMED:18407067] [PUBMED:18411289] [PUBMED:18778407] [PUBMED:20123714] [PUBMED:20158475] [PUBMED:19779561] [PUBMED:18026123] [PUBMED:19930040] [PUBMED:12675800] [PUBMED:11755407] [PUBMED:11489966] [PUBMED:19775254] [PUBMED:20943123] [PUBMED:17690885] [PUBMED:16938850] [PUBMED:20526845] [PUBMED:11567004] [PUBMED:17074883] [PUBMED:11825778] [PUBMED:17071592] [PUBMED:16800847] [PUBMED:16611232] [PUBMED:10499590]
TBC/RABGAPs [NCBI:1470925] [REACTOME:R-HSA-8854214] [PUBMED:16855591] [PUBMED:22251903]
Tuberculosis [NCBI:213780] [KEGG:hsa05152] [PUBMED:20199890] [PUBMED:21274449] [PUBMED:17359235] [PUBMED:20415982] [PUBMED:18541216] [PUBMED:19369951] [PUBMED:15083155] [PUBMED:11378475] [PUBMED:15228522] [PUBMED:19634703] [PUBMED:21274433] [PUBMED:19563525] [PUBMED:18407066] [PUBMED:18288961] [PUBMED:16200082] [PUBMED:17785780] [PUBMED:11932234]
Vesicle-mediated transport [NCBI:1269876] [REACTOME:R-HSA-5653656]