full name
angiotensin II receptor type 1
synonyms
AG2S, AGTR1A, AGTR1B, AT1, AT1AR, AT1B, AT1BR, AT1R, AT2R1, AT2R1A, AT2R1B, HAT1R, AGTR1, ENSG00000144891
HGNC
HGNC:336
Entrez Gene
Gene:185
ENSEMBL
ENSG00000144891
location
chr: 3
start: 148415658
stop: 148460790
strand: +
OMIM
OMIM:106165:
AGTR1
(Autosomal recessive inheritance)
OMIM:267430:
Renal tubular dysgenesis
OMIM:145500:
{Hypertension, essential}
transcripts
NM_031850.3
NM_000685.4
NM_004835.4
NM_009585.3
NM_032049.3
pathways
AGE-RAGE signaling pathway in diabetic complications
[NCBI:1319988]
[KEGG:hsa04933]
[PUBMED:23776698]
[PUBMED:15569303]
[PUBMED:16894049]
[PUBMED:18323529]
[PUBMED:11375353]
[PUBMED:21111800]
[PUBMED:19404313]
[PUBMED:20470857]
[PUBMED:17005604]
[PUBMED:23961320]
[PUBMED:21261520]
[PUBMED:11180401]
[PUBMED:18922799]
[PUBMED:21680901]
[PUBMED:11684565]
[PUBMED:21590515]
[PUBMED:12709399]
[PUBMED:20300563]
[PUBMED:21440603]
[PUBMED:22558488]
Adrenergic signaling in cardiomyocytes
[NCBI:908257]
[KEGG:hsa04261]
[PUBMED:15232578]
[PUBMED:20923637]
[PUBMED:10571541]
[PUBMED:11604549]
[PUBMED:17988210]
[PUBMED:11805843]
[PUBMED:15142747]
[PUBMED:21212391]
[PUBMED:20658186]
[PUBMED:16765984]
[PUBMED:19874988]
[PUBMED:19883653]
[PUBMED:15979723]
[PUBMED:18407781]
[PUBMED:22022314]
[PUBMED:12439640]
[PUBMED:17826821]
[PUBMED:15765137]
Aldosterone synthesis and secretion
[NCBI:1272485]
[KEGG:hsa04925]
[PUBMED:15044681]
[PUBMED:10536682]
[PUBMED:24944029]
[PUBMED:25788893]
[PUBMED:15026188]
[PUBMED:22689262]
[PUBMED:22364774]
[PUBMED:18406824]
[PUBMED:14645496]
[PUBMED:21839803]
[PUBMED:22395411]
[PUBMED:23628605]
[PUBMED:21962440]
Angiopoietin receptor Tie2-mediated signaling
[NCBI:137917]
[Pathway Interaction Database:angiopoietinreceptor_pathway]
[PUBMED:9204896]
[PUBMED:12609966]
[PUBMED:14726409]
[PUBMED:11157678]
[PUBMED:10347092]
[PUBMED:11967990]
[PUBMED:15162796]
[PUBMED:11289054]
[PUBMED:12759249]
[PUBMED:10051567]
[PUBMED:12824293]
[PUBMED:16895971]
[PUBMED:10807867]
[PUBMED:12933576]
[PUBMED:11513602]
[PUBMED:12074640]
[PUBMED:8980223]
[PUBMED:14665640]
[PUBMED:15132996]
[PUBMED:10944458]
[PUBMED:11230987]
[PUBMED:15242771]
[PUBMED:10585289]
[PUBMED:16061664]
[PUBMED:10376602]
[PUBMED:15350545]
[PUBMED:9632797]
[PUBMED:10625301]
[PUBMED:9926914]
[PUBMED:17189382]
[PUBMED:11139469]
[PUBMED:11689432]
[PUBMED:11416142]
[PUBMED:11166279]
[PUBMED:15284220]
[PUBMED:15985432]
[PUBMED:16049136]
[PUBMED:16157706]
[PUBMED:10521483]
[PUBMED:12816861]
[PUBMED:9478921]
[PUBMED:10376603]
[PUBMED:15769741]
[PUBMED:12890486]
[PUBMED:14749497]
[PUBMED:7561682]
[PUBMED:11801735]
[PUBMED:12665569]
[PUBMED:12117724]
[PUBMED:9764820]
Apelin signaling pathway
[NCBI:1492886]
[KEGG:hsa04371]
[PUBMED:23973488]
[PUBMED:16182514]
[PUBMED:21725702]
[PUBMED:22842084]
[PUBMED:27825851]
[PUBMED:27650065]
[PUBMED:22140623]
[PUBMED:23943882]
[PUBMED:26944568]
[PUBMED:24055369]
[PUBMED:26385179]
[PUBMED:26143239]
[PUBMED:22028387]
[PUBMED:26254105]
[PUBMED:26756969]
[PUBMED:22995518]
[PUBMED:27979574]
[PUBMED:23924696]
[PUBMED:21464822]
[PUBMED:25914650]
[PUBMED:24990699]
[PUBMED:26607438]
[PUBMED:25164121]
[PUBMED:25275559]
[PUBMED:25139773]
[PUBMED:25931124]
[PUBMED:19093215]
[PUBMED:20539939]
[PUBMED:25652330]
[PUBMED:18272138]
[PUBMED:23603510]
Arf6 signaling events
[NCBI:138034]
[Pathway Interaction Database:arf6_pathway]
[PUBMED:18164504]
[PUBMED:15509780]
[PUBMED:11481345]
[PUBMED:18084281]
[PUBMED:15775968]
[PUBMED:18094045]
[PUBMED:17409355]
[PUBMED:11532961]
[PUBMED:10480924]
[PUBMED:15126638]
[PUBMED:17398097]
[PUBMED:18026091]
[PUBMED:17353194]
[PUBMED:15793570]
[PUBMED:16650966]
[PUBMED:12920129]
[PUBMED:11278939]
[PUBMED:9742223]
[PUBMED:11062263]
[PUBMED:16461286]
[PUBMED:10779358]
[PUBMED:18003747]
[PUBMED:15923660]
[PUBMED:10642533]
[PUBMED:11342560]
[PUBMED:10448098]
[PUBMED:11226253]
[PUBMED:18490450]
[PUBMED:19193766]
[PUBMED:10913124]
[PUBMED:10811902]
[PUBMED:17077126]
[PUBMED:11533043]
[PUBMED:12447393]
[PUBMED:10333475]
[PUBMED:9550703]
[PUBMED:10075920]
[PUBMED:9417041]
[PUBMED:17719203]
[PUBMED:14625293]
[PUBMED:17122362]
[PUBMED:17846866]
Calcium signaling pathway
[NCBI:83050]
[KEGG:hsa04020]
[PUBMED:11080247]
[PUBMED:14572802]
[PUBMED:11413485]
[PUBMED:22129055]
[PUBMED:10508738]
[PUBMED:15000521]
[PUBMED:9235901]
[PUBMED:7861177]
[PUBMED:9149541]
[PUBMED:14517314]
[PUBMED:15111104]
[PUBMED:11698232]
[PUBMED:10331643]
[PUBMED:12838335]
[PUBMED:8125957]
[PUBMED:19172794]
[PUBMED:10997573]
[PUBMED:21338471]
[PUBMED:11299192]
[PUBMED:22002090]
[PUBMED:12972622]
Cargo recognition for clathrin-mediated endocytosis
[NCBI:1427859]
[REACTOME:R-HSA-8856825]
[PUBMED:24186068]
[PUBMED:12952941]
[PUBMED:19696796]
[PUBMED:14985334]
[PUBMED:20448150]
[PUBMED:20485680]
[PUBMED:16382132]
[PUBMED:23482940]
[PUBMED:16870701]
Class A/1 (Rhodopsin-like receptors)
[NCBI:1269545]
[REACTOME:R-HSA-373076]
[PUBMED:16902930]
Clathrin-mediated endocytosis
[NCBI:1427858]
[REACTOME:R-HSA-8856828]
[PUBMED:16516836]
[PUBMED:15339664]
[PUBMED:19754444]
[PUBMED:8552632]
[PUBMED:21779028]
[PUBMED:12353027]
[PUBMED:23891661]
[PUBMED:21613550]
[PUBMED:20059951]
[PUBMED:21447041]
[PUBMED:17620409]
[PUBMED:16903783]
[PUBMED:21445324]
[PUBMED:19696798]
[PUBMED:26246598]
[PUBMED:25085911]
[PUBMED:24186068]
[PUBMED:26829388]
[PUBMED:27092250]
[PUBMED:24581490]
[PUBMED:26042225]
[PUBMED:23823722]
[PUBMED:24789820]
[PUBMED:9736607]
[PUBMED:23637288]
[PUBMED:22233676]
[PUBMED:19458185]
[PUBMED:26403691]
[PUBMED:19296720]
[PUBMED:15703209]
[PUBMED:20428113]
[PUBMED:8953040]
[PUBMED:1177317]
[PUBMED:9092476]
[PUBMED:26872272]
[PUBMED:19092055]
G alpha (q) signalling events
[NCBI:1269578]
[REACTOME:R-HSA-416476]
[PUBMED:19212139]
GPCR downstream signaling
[NCBI:1269574]
[REACTOME:R-HSA-388396]
[PUBMED:12040175]
GPCR ligand binding
[NCBI:1269544]
[REACTOME:R-HSA-500792]
[PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK
[NCBI:1269592]
[REACTOME:R-HSA-881907]
[PUBMED:10413847]
[PUBMED:7491953]
[PUBMED:17698287]
Membrane Trafficking
[NCBI:1269877]
[REACTOME:R-HSA-199991]
[PUBMED:11031247]
Neuroactive ligand-receptor interaction
[NCBI:83053]
[KEGG:hsa04080]
Pathways in cancer
[NCBI:83105]
[KEGG:hsa05200]
[PUBMED:12244301]
[PUBMED:15156182]
[PUBMED:16899407]
[PUBMED:12621137]
[PUBMED:21193867]
[PUBMED:16001072]
[PUBMED:11707511]
[PUBMED:11253051]
[PUBMED:11071626]
[PUBMED:17251915]
[PUBMED:11736900]
[PUBMED:16557281]
[PUBMED:16699851]
[PUBMED:16189702]
[PUBMED:11902573]
[PUBMED:16555243]
[PUBMED:8069858]
[PUBMED:15310786]
[PUBMED:9834202]
[PUBMED:16700615]
[PUBMED:12545153]
[PUBMED:15656799]
[PUBMED:12154354]
[PUBMED:11895903]
[PUBMED:11527574]
[PUBMED:16326109]
[PUBMED:16339096]
[PUBMED:11160144]
[PUBMED:15724144]
[PUBMED:12951584]
[PUBMED:10647931]
[PUBMED:16881963]
[PUBMED:15557758]
[PUBMED:11477132]
[PUBMED:15721476]
[PUBMED:15625120]
[PUBMED:16236521]
[PUBMED:14967450]
[PUBMED:15942304]
[PUBMED:17287871]
[PUBMED:14634372]
[PUBMED:15573119]
[PUBMED:15009714]
[PUBMED:16112428]
[PUBMED:15611513]
[PUBMED:16001050]
[PUBMED:15349822]
[PUBMED:16551846]
[PUBMED:15978322]
[PUBMED:15774796]
[PUBMED:16352814]
[PUBMED:12951588]
[PUBMED:10944551]
[PUBMED:10740269]
[PUBMED:15639402]
[PUBMED:12407699]
[PUBMED:11130178]
[PUBMED:15109562]
[PUBMED:11170304]
[PUBMED:11276000]
[PUBMED:9643506]
[PUBMED:16248975]
[PUBMED:16242838]
[PUBMED:12946833]
[PUBMED:11559746]
[PUBMED:9196022]
[PUBMED:12079267]
[PUBMED:15468170]
[PUBMED:16064138]
[PUBMED:14580692]
[PUBMED:15082523]
[PUBMED:15551095]
[PUBMED:17062879]
[PUBMED:17211469]
[PUBMED:11720739]
[PUBMED:12588368]
[PUBMED:11057895]
[PUBMED:9422516]
[PUBMED:12894244]
[PUBMED:15479695]
[PUBMED:16189154]
[PUBMED:12878745]
[PUBMED:11900250]
[PUBMED:11103787]
[PUBMED:15122209]
[PUBMED:12711111]
[PUBMED:12243753]
[PUBMED:16306523]
[PUBMED:16702400]
[PUBMED:15270885]
[PUBMED:14685170]
[PUBMED:14586404]
[PUBMED:11078609]
[PUBMED:15284264]
[PUBMED:10505543]
[PUBMED:11223406]
[PUBMED:14982876]
[PUBMED:12648469]
[PUBMED:12867060]
[PUBMED:15711891]
[PUBMED:12094241]
[PUBMED:16642045]
[PUBMED:11463388]
[PUBMED:12762887]
[PUBMED:15746962]
[PUBMED:15823750]
[PUBMED:16750612]
[PUBMED:16484590]
[PUBMED:11459867]
[PUBMED:16146838]
[PUBMED:14556242]
[PUBMED:15947972]
[PUBMED:12563308]
[PUBMED:16946003]
[PUBMED:15948971]
[PUBMED:11407945]
[PUBMED:12737309]
[PUBMED:16095998]
[PUBMED:12351585]
[PUBMED:24508914]
[PUBMED:12084351]
[PUBMED:11807782]
[PUBMED:14695152]
[PUBMED:10453277]
[PUBMED:17554387]
[PUBMED:15841168]
[PUBMED:12616528]
[PUBMED:10403855]
[PUBMED:16054233]
[PUBMED:16474624]
[PUBMED:16822996]
[PUBMED:17028294]
[PUBMED:11224709]
[PUBMED:11750244]
[PUBMED:11905738]
[PUBMED:15719031]
[PUBMED:10843728]
[PUBMED:16110317]
[PUBMED:11721960]
[PUBMED:12741677]
[PUBMED:7585656]
[PUBMED:12801837]
[PUBMED:16551847]
[PUBMED:12459728]
[PUBMED:11431710]
[PUBMED:12468433]
[PUBMED:11165748]
[PUBMED:16042571]
[PUBMED:16508724]
[PUBMED:15000146]
[PUBMED:17149381]
[PUBMED:15948711]
[PUBMED:14747944]
[PUBMED:14737121]
[PUBMED:12379883]
[PUBMED:17158541]
[PUBMED:12850530]
[PUBMED:10835690]
[PUBMED:16870043]
Peptide ligand-binding receptors
[NCBI:1269546]
[REACTOME:R-HSA-375276]
[PUBMED:14576899]
[PUBMED:10977869]
[PUBMED:16918325]
[PUBMED:16847439]
[PUBMED:17293890]
[PUBMED:15734727]
[PUBMED:12895595]
[PUBMED:17604107]
[PUBMED:14507421]
[PUBMED:12432945]
[PUBMED:16612131]
Phospholipase D signaling pathway
[NCBI:1311074]
[KEGG:hsa04072]
[PUBMED:9310372]
[PUBMED:9119890]
[PUBMED:15310762]
[PUBMED:18936782]
[PUBMED:24990952]
[PUBMED:14769825]
[PUBMED:21936578]
[PUBMED:10666319]
[PUBMED:17210675]
[PUBMED:19264150]
[PUBMED:23076158]
[PUBMED:17054901]
[PUBMED:16622417]
[PUBMED:10807766]
[PUBMED:12217395]
[PUBMED:11042115]
[PUBMED:19815110]
[PUBMED:24995811]
[PUBMED:16143829]
[PUBMED:8135758]
[PUBMED:11991733]
[PUBMED:19410013]
[PUBMED:17245604]
Renin secretion
[NCBI:1222951]
[KEGG:hsa04924]
[PUBMED:24944035]
[PUBMED:22733355]
[PUBMED:20936939]
[PUBMED:12949225]
[PUBMED:17360952]
[PUBMED:17928544]
[PUBMED:19948673]
[PUBMED:12388321]
[PUBMED:15283749]
[PUBMED:22237158]
[PUBMED:22258323]
[PUBMED:9882634]
[PUBMED:20393195]
[PUBMED:22124804]
Renin-angiotensin system
[NCBI:83075]
[KEGG:hsa04614]
[PUBMED:16581295]
[PUBMED:15549172]
[PUBMED:12019279]
[PUBMED:18793332]
[PUBMED:12793984]
[PUBMED:12505055]
[PUBMED:23692861]
[PUBMED:17229979]
[PUBMED:12372844]
[PUBMED:15173164]
[PUBMED:15833268]
[PUBMED:21951628]
[PUBMED:25332897]
[PUBMED:16286563]
[PUBMED:12419208]
[PUBMED:24760442]
[PUBMED:15109615]
[PUBMED:24273531]
[PUBMED:16555051]
[PUBMED:15549171]
[PUBMED:17362841]
Signal Transduction
[NCBI:1269379]
[REACTOME:R-HSA-162582]
[PUBMED:17604717]
[PUBMED:19648010]
[PUBMED:16260143]
[PUBMED:11742412]
[PUBMED:19536106]
[PUBMED:15863030]
[PUBMED:19379690]
[PUBMED:19458711]
[PUBMED:19935667]
[PUBMED:21252999]
[PUBMED:15520807]
[PUBMED:17496910]
[PUBMED:15450248]
[PUBMED:18043707]
[PUBMED:16939974]
[PUBMED:19762341]
[PUBMED:18483217]
[PUBMED:17084981]
[PUBMED:21781017]
[PUBMED:19619488]
Signaling by GPCR
[NCBI:1269543]
[REACTOME:R-HSA-372790]
[PUBMED:16902930]
[PUBMED:10202136]
[PUBMED:18043707]
Vascular smooth muscle contraction
[NCBI:96530]
[KEGG:hsa04270]
[PUBMED:16870827]
[PUBMED:10911373]
[PUBMED:11679404]
[PUBMED:16339747]
[PUBMED:10221985]
[PUBMED:12689814]
[PUBMED:11165670]
[PUBMED:18552454]
[PUBMED:12060106]
[PUBMED:9458738]
[PUBMED:15725705]
[PUBMED:18040024]
[PUBMED:12693609]
[PUBMED:11773611]
[PUBMED:17158339]
[PUBMED:17458653]
[PUBMED:15026027]
[PUBMED:19120701]
[PUBMED:15269340]
[PUBMED:18703404]
[PUBMED:11709400]
[PUBMED:17200683]
Vesicle-mediated transport
[NCBI:1269876]
[REACTOME:R-HSA-5653656]
cGMP-PKG signaling pathway
[NCBI:983748]
[KEGG:hsa04022]
[PUBMED:18006449]
[PUBMED:9003029]
[PUBMED:18040025]
[PUBMED:19306895]
[PUBMED:21666108]
[PUBMED:12524221]
[PUBMED:16460276]
[PUBMED:20716671]
[PUBMED:22785374]
[PUBMED:11522789]
[PUBMED:16439998]
[PUBMED:16371594]
[PUBMED:20388537]
[PUBMED:18757523]
[PUBMED:16815627]
[PUBMED:23212367]
[PUBMED:21685243]
[PUBMED:20024580]
[PUBMED:15894227]
[PUBMED:22965426]
[PUBMED:17643091]
[PUBMED:19176601]
[PUBMED:19961855]