full name
DEAH-box helicase 36

synonyms
DDX36, G4R1, MLEL1, RHAU, DHX36, ENSG00000174953

HGNC
HGNC:14410

Entrez Gene
Gene:170506

ENSEMBL
ENSG00000174953

location
chr: 3
start: 153993452
stop: 154042286
strand: -

transcripts
NM_001114397.1
NM_020865.2

pathways
Cytosolic sensors of pathogen-associated DNA [NCBI:1269268] [REACTOME:R-HSA-1834949] [PUBMED:23706668] [PUBMED:21533068] [PUBMED:23706667]
DEx/H-box helicases activate type I IFN and inflammatory cytokines production [NCBI:1269276] [REACTOME:R-HSA-3134963] [PUBMED:20696886]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
MyD88 dependent cascade initiated on endosome [NCBI:1269228] [REACTOME:R-HSA-975155] [PUBMED:20237413] [PUBMED:15276183] [PUBMED:18652679]
RIG-I/MDA5 mediated induction of IFN-alpha/beta pathways [NCBI:1269259] [REACTOME:R-HSA-168928] [PUBMED:17395582] [PUBMED:17942531] [PUBMED:18701081] [PUBMED:17683970] [PUBMED:18989317] [PUBMED:16214811]
RNA degradation [NCBI:117291] [KEGG:hsa03018] [PUBMED:16939780] [PUBMED:17560162] [PUBMED:17471261] [PUBMED:16968219] [PUBMED:16766188] [PUBMED:17447862] [PUBMED:19239894]
TRAF6 mediated IRF7 activation [NCBI:1269262] [REACTOME:R-HSA-933541] [PUBMED:19479062]
TRAF6 mediated IRF7 activation in TLR7/8 or 9 signaling [NCBI:1269232] [REACTOME:R-HSA-975110] [PUBMED:16214811] [PUBMED:11070172]
Toll Like Receptor 7/8 (TLR7/8) Cascade [NCBI:1269227] [REACTOME:R-HSA-168181] [PUBMED:14976262]
Toll Like Receptor 9 (TLR9) Cascade [NCBI:1269233] [REACTOME:R-HSA-168138] [PUBMED:14751759]
Toll-Like Receptors Cascades [NCBI:1269204] [REACTOME:R-HSA-168898] [PUBMED:15950447] [PUBMED:12893815] [PUBMED:15976490] [PUBMED:15585605] [PUBMED:14751757]