full name
protein kinase C iota

synonyms
DXS1179E, nPKC-iota, PKCI, PRKCI, ENSG00000163558

HGNC
HGNC:9404

Entrez Gene
Gene:5584

ENSEMBL
ENSG00000163558

location
chr: 3
start: 169940220
stop: 170023770
strand: +

transcripts
NM_002740.5

pathways
Cell junction organization [NCBI:1270232] [REACTOME:R-HSA-446728]
Cell-Cell communication [NCBI:1270231] [REACTOME:R-HSA-1500931] [PUBMED:20554646] [PUBMED:12598678] [PUBMED:17766183] [PUBMED:18837673] [PUBMED:16691243] [PUBMED:1616050]
Cell-cell junction organization [NCBI:1270233] [REACTOME:R-HSA-421270] [PUBMED:16487793] [PUBMED:1616050] [PUBMED:19081036] [PUBMED:16537104] [PUBMED:17854762]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
Hippo signaling pathway [NCBI:749777] [KEGG:hsa04390] [PUBMED:18955139] [PUBMED:20439427] [PUBMED:20951342] [PUBMED:21138973] [PUBMED:18328423] [PUBMED:21324984] [PUBMED:23034192] [PUBMED:21808241] [PUBMED:17975546] [PUBMED:22750148] [PUBMED:21084559] [PUBMED:19846288] [PUBMED:22895435] [PUBMED:22683405] [PUBMED:22658639] [PUBMED:22153608] [PUBMED:20945341] [PUBMED:22830020] [PUBMED:21874053] [PUBMED:21376238]
IL1-mediated signaling events [NCBI:137944] [Pathway Interaction Database:il1pathway] [PUBMED:10854325] [PUBMED:11287640] [PUBMED:10747026] [PUBMED:11960013] [PUBMED:12150927] [PUBMED:1837145] [PUBMED:17197697] [PUBMED:9374458] [PUBMED:12721283] [PUBMED:8035875] [PUBMED:9261174] [PUBMED:9734363] [PUBMED:11460167] [PUBMED:7878046] [PUBMED:10373529] [PUBMED:2530587] [PUBMED:12538665] [PUBMED:10882101] [PUBMED:9360994] [PUBMED:9062194] [PUBMED:12242293] [PUBMED:8837778] [PUBMED:9430229] [PUBMED:7775431]
Insulin Pathway [NCBI:138026] [Pathway Interaction Database:insulin_pathway] [PUBMED:8491186] [PUBMED:9111325] [PUBMED:7629070] [PUBMED:10499514] [PUBMED:11121405] [PUBMED:10660596] [PUBMED:8196603] [PUBMED:11096081] [PUBMED:8524328] [PUBMED:9891043] [PUBMED:12242347] [PUBMED:2123524] [PUBMED:9369444] [PUBMED:1375946] [PUBMED:9348199] [PUBMED:8826975] [PUBMED:8316835] [PUBMED:8999839] [PUBMED:8449939] [PUBMED:10807907] [PUBMED:1599438] [PUBMED:8265614] [PUBMED:11171109] [PUBMED:11821390] [PUBMED:12687004] [PUBMED:7806540] [PUBMED:11154281] [PUBMED:8244979] [PUBMED:8798417] [PUBMED:1381348] [PUBMED:7581368] [PUBMED:15787604] [PUBMED:8385105] [PUBMED:11551902] [PUBMED:8114695] [PUBMED:11997497] [PUBMED:11001060] [PUBMED:11309621] [PUBMED:9109420] [PUBMED:8383963] [PUBMED:12147684] [PUBMED:8144662] [PUBMED:12036959] [PUBMED:14734537] [PUBMED:7983051] [PUBMED:9083103] [PUBMED:15210700] [PUBMED:9065430] [PUBMED:11297536] [PUBMED:10544179] [PUBMED:1321126] [PUBMED:11502760] [PUBMED:8978681] [PUBMED:8999972] [PUBMED:14690593] [PUBMED:11832334] [PUBMED:9447983] [PUBMED:15192089] [PUBMED:8524413] [PUBMED:7685165] [PUBMED:10329736] [PUBMED:11287630] [PUBMED:15486046] [PUBMED:10330191] [PUBMED:8626723]
Insulin signaling pathway [NCBI:83090] [KEGG:hsa04910] [PUBMED:11742412] [PUBMED:11343120] [PUBMED:15733744] [PUBMED:11282018] [PUBMED:10196204] [PUBMED:18291668] [PUBMED:9609110] [PUBMED:10567225] [PUBMED:12791379] [PUBMED:9748166] [PUBMED:15624019] [PUBMED:9445476] [PUBMED:9346240] [PUBMED:14635525] [PUBMED:16288289] [PUBMED:12867054] [PUBMED:15229476] [PUBMED:17344645] [PUBMED:9609111]
Insulin-mediated glucose transport [NCBI:137981] [Pathway Interaction Database:insulin_glucose_pathway] [PUBMED:16880201] [PUBMED:9267469] [PUBMED:17059388] [PUBMED:2123524] [PUBMED:8392229] [PUBMED:9819385] [PUBMED:11001060] [PUBMED:10394363] [PUBMED:10869347] [PUBMED:11994271] [PUBMED:11997497] [PUBMED:11309621] [PUBMED:16213228] [PUBMED:15616009] [PUBMED:9582355] [PUBMED:15254270] [PUBMED:12637568] [PUBMED:8816781] [PUBMED:11102509] [PUBMED:16055084] [PUBMED:10364240] [PUBMED:9712142]
Neurotrophic factor-mediated Trk receptor signaling [NCBI:137977] [Pathway Interaction Database:trkrpathway] [PUBMED:1849459] [PUBMED:8226808] [PUBMED:11163269] [PUBMED:7510697] [PUBMED:11027277] [PUBMED:15758069] [PUBMED:11425862] [PUBMED:11238898] [PUBMED:11251075] [PUBMED:8344249] [PUBMED:9356464] [PUBMED:11150291] [PUBMED:10092678] [PUBMED:1280261] [PUBMED:11150334] [PUBMED:11244088] [PUBMED:10985348] [PUBMED:15753086] [PUBMED:1653651] [PUBMED:11466412] [PUBMED:15167895] [PUBMED:1831195] [PUBMED:10490030] [PUBMED:8384556] [PUBMED:16697063] [PUBMED:17003042] [PUBMED:15520226] [PUBMED:15632082] [PUBMED:16611639] [PUBMED:16187212] [PUBMED:9182757] [PUBMED:1604323] [PUBMED:16284401] [PUBMED:8356095] [PUBMED:10329710] [PUBMED:9927421] [PUBMED:9856458] [PUBMED:10691301] [PUBMED:1375038] [PUBMED:10679771] [PUBMED:15122257] [PUBMED:15513915] [PUBMED:16701206] [PUBMED:1710174] [PUBMED:8155326] [PUBMED:8288573] [PUBMED:7972023] [PUBMED:7512734] [PUBMED:10601297] [PUBMED:16203995] [PUBMED:12510192] [PUBMED:16481401] [PUBMED:8106527] [PUBMED:11278445] [PUBMED:9099755] [PUBMED:1850821] [PUBMED:9632781] [PUBMED:10235685] [PUBMED:15917464] [PUBMED:9285826] [PUBMED:12446789] [PUBMED:7657612] [PUBMED:1850549] [PUBMED:12879077] [PUBMED:16157584] [PUBMED:10207144] [PUBMED:12006576] [PUBMED:8052307] [PUBMED:8382740] [PUBMED:10629055]
Platelet activation [NCBI:952858] [KEGG:hsa04611] [PUBMED:20002545] [PUBMED:18363565] [PUBMED:18544684] [PUBMED:18174460] [PUBMED:23106920] [PUBMED:18550847] [PUBMED:22119499] [PUBMED:19630797] [PUBMED:19286885] [PUBMED:17158345] [PUBMED:20089227] [PUBMED:22701130] [PUBMED:21071698] [PUBMED:23805129] [PUBMED:16149014] [PUBMED:18641368]
Rap1 signaling pathway [NCBI:868086] [KEGG:hsa04015] [PUBMED:17624944] [PUBMED:12351703] [PUBMED:10579920] [PUBMED:19159611] [PUBMED:18363565] [PUBMED:12765839] [PUBMED:12508104] [PUBMED:11331911] [PUBMED:17182900] [PUBMED:15803158] [PUBMED:19615876] [PUBMED:21402149] [PUBMED:17624948] [PUBMED:17383543] [PUBMED:14607972] [PUBMED:15780587] [PUBMED:19710505]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
TNF receptor signaling pathway [NCBI:138053] [Pathway Interaction Database:tnfpathway] [PUBMED:17024246] [PUBMED:7923351] [PUBMED:9774977] [PUBMED:15258597] [PUBMED:11429546] [PUBMED:10848577] [PUBMED:12917689] [PUBMED:11031259] [PUBMED:8974401] [PUBMED:7758105] [PUBMED:10510344] [PUBMED:15793306] [PUBMED:12391233] [PUBMED:18450452] [PUBMED:15218148] [PUBMED:8692885] [PUBMED:10026132] [PUBMED:9275185] [PUBMED:11684013] [PUBMED:8521496] [PUBMED:12917690] [PUBMED:10795740] [PUBMED:16603398] [PUBMED:9405407] [PUBMED:2158863] [PUBMED:16260783] [PUBMED:8808629] [PUBMED:9034190] [PUBMED:16543241] [PUBMED:12077366] [PUBMED:9384583] [PUBMED:8612133] [PUBMED:9712898] [PUBMED:1313189] [PUBMED:8069916] [PUBMED:11907583] [PUBMED:9639556] [PUBMED:12917691] [PUBMED:9115275] [PUBMED:8681376] [PUBMED:10356400] [PUBMED:10801798] [PUBMED:10097111] [PUBMED:8565075] [PUBMED:10187805] [PUBMED:15357952] [PUBMED:9915703] [PUBMED:9564042] [PUBMED:8943045]
Tight junction [NCBI:83071] [KEGG:hsa04530] [PUBMED:25152334] [PUBMED:16650994] [PUBMED:22892070] [PUBMED:18946474] [PUBMED:12042308] [PUBMED:23885123] [PUBMED:16771626] [PUBMED:17182900] [PUBMED:21283798] [PUBMED:25757376] [PUBMED:22928510] [PUBMED:22169974] [PUBMED:25469537] [PUBMED:24651541] [PUBMED:15820555] [PUBMED:17525755] [PUBMED:27353478] [PUBMED:17950242] [PUBMED:18005931] [PUBMED:24548561] [PUBMED:21781017] [PUBMED:20094051] [PUBMED:20134025] [PUBMED:22896795] [PUBMED:18094055] [PUBMED:25483301]
Tight junction interactions [NCBI:1270236] [REACTOME:R-HSA-420029] [PUBMED:12612641] [PUBMED:17452622] [PUBMED:16923393] [PUBMED:18365233] [PUBMED:11283726]
p75 NTR receptor-mediated signalling [NCBI:1269445] [REACTOME:R-HSA-193704] [PUBMED:16699811] [PUBMED:16939974] [PUBMED:12671646]
p75(NTR)-mediated signaling [NCBI:138019] [Pathway Interaction Database:p75ntrpathway] [PUBMED:14673001] [PUBMED:14593116] [PUBMED:10545116] [PUBMED:11729324] [PUBMED:16252010] [PUBMED:11756426] [PUBMED:12414813] [PUBMED:2157470] [PUBMED:11777929] [PUBMED:1547788] [PUBMED:10764727] [PUBMED:8614802] [PUBMED:14960584] [PUBMED:12376548] [PUBMED:11756498] [PUBMED:8079174] [PUBMED:16498402] [PUBMED:15051733] [PUBMED:12682012] [PUBMED:14638693] [PUBMED:14966521] [PUBMED:9915784] [PUBMED:11487608] [PUBMED:10485890] [PUBMED:16630834] [PUBMED:11312266] [PUBMED:10985348] [PUBMED:11244088] [PUBMED:6093111] [PUBMED:10595511] [PUBMED:14985763] [PUBMED:12097334] [PUBMED:15548667] [PUBMED:15470142] [PUBMED:11279271] [PUBMED:8878481] [PUBMED:12422217] [PUBMED:15987945] [PUBMED:15668238] [PUBMED:10433815] [PUBMED:12692556] [PUBMED:2025430] [PUBMED:15930396] [PUBMED:11278287] [PUBMED:12034707]
p75NTR recruits signalling complexes [NCBI:1269453] [REACTOME:R-HSA-209543]
p75NTR signals via NF-kB [NCBI:1269452] [REACTOME:R-HSA-193639] [PUBMED:16997282]