full name
phospholipase D1

synonyms
PLD1, ENSG00000075651

HGNC
HGNC:9067

Entrez Gene
Gene:5337

ENSEMBL
ENSG00000075651

location
chr: 3
start: 171318195
stop: 171528284
strand: -

OMIM
OMIM:602382: PLD1
OMIM:212093: Cardiac valvular defect, developmental

transcripts
NM_001130081.2
NM_002662.4

pathways
Alpha-synuclein signaling [NCBI:137913] [Pathway Interaction Database:alphasynuclein_pathway] [PUBMED:12551928] [PUBMED:15671022] [PUBMED:12887682] [PUBMED:14991825] [PUBMED:11431533] [PUBMED:11588587] [PUBMED:16030137] [PUBMED:15845543] [PUBMED:11590439] [PUBMED:12096713] [PUBMED:11687285] [PUBMED:15978696] [PUBMED:10407019] [PUBMED:11078745] [PUBMED:16403519] [PUBMED:14985429] [PUBMED:14645218] [PUBMED:12787066] [PUBMED:11292651] [PUBMED:12421356] [PUBMED:15944382] [PUBMED:10567343] [PUBMED:11744621] [PUBMED:15935068] [PUBMED:12928483] [PUBMED:11821392] [PUBMED:10852916]
Arf6 downstream pathway [NCBI:138038] [Pathway Interaction Database:arf6downstreampathway] [PUBMED:12388770] [PUBMED:14565977] [PUBMED:10036235] [PUBMED:14764880] [PUBMED:12447393] [PUBMED:9312003] [PUBMED:17077126] [PUBMED:17363898] [PUBMED:14505574] [PUBMED:16280360] [PUBMED:17628206] [PUBMED:15601896] [PUBMED:10913182] [PUBMED:16452216] [PUBMED:7753201] [PUBMED:15210957] [PUBMED:16880525] [PUBMED:16181626] [PUBMED:17640372] [PUBMED:11481345] [PUBMED:17409355] [PUBMED:12379803] [PUBMED:18084281] [PUBMED:10589680] [PUBMED:11532961] [PUBMED:17353194] [PUBMED:8769418] [PUBMED:10779358] [PUBMED:18026091] [PUBMED:12509462] [PUBMED:15087504] [PUBMED:9664047]
Arf6 trafficking events [NCBI:137954] [Pathway Interaction Database:arf6_traffickingpathway] [PUBMED:10748097] [PUBMED:15590645] [PUBMED:15980073] [PUBMED:19644450] [PUBMED:16461286] [PUBMED:14675422] [PUBMED:16139226] [PUBMED:12589044] [PUBMED:15802264] [PUBMED:14585928] [PUBMED:17664335] [PUBMED:17719203] [PUBMED:12960436] [PUBMED:12447393] [PUBMED:11535619] [PUBMED:12657640] [PUBMED:16280360] [PUBMED:9314528] [PUBMED:19211056] [PUBMED:11533043] [PUBMED:12847086] [PUBMED:15146059] [PUBMED:9685333] [PUBMED:12925709] [PUBMED:15231847] [PUBMED:12810696] [PUBMED:14662749] [PUBMED:16030257] [PUBMED:12379803] [PUBMED:15775968] [PUBMED:11532961] [PUBMED:8769418]
CDC42 signaling events [NCBI:137994] [Pathway Interaction Database:cdc42_pathway] [PUBMED:7629060] [PUBMED:7652575] [PUBMED:8653792] [PUBMED:18448434] [PUBMED:19822663] [PUBMED:19454477] [PUBMED:18662680] [PUBMED:15882626] [PUBMED:11948177] [PUBMED:9860974] [PUBMED:15225553] [PUBMED:8643625] [PUBMED:8107774] [PUBMED:8670801] [PUBMED:8034624] [PUBMED:10934474] [PUBMED:10734320] [PUBMED:17522712] [PUBMED:11525734] [PUBMED:15649357] [PUBMED:10473551] [PUBMED:16157700] [PUBMED:9822598] [PUBMED:15723051] [PUBMED:7600582] [PUBMED:18319301] [PUBMED:9042860] [PUBMED:10613909] [PUBMED:17580073] [PUBMED:12745076] [PUBMED:16253996] [PUBMED:10840034] [PUBMED:10360579] [PUBMED:11907268] [PUBMED:10934475] [PUBMED:10219243] [PUBMED:17038317] [PUBMED:8910292] [PUBMED:9403696] [PUBMED:11285260] [PUBMED:10995437] [PUBMED:9368021] [PUBMED:14970210] [PUBMED:9694656] [PUBMED:14505571] [PUBMED:17115031] [PUBMED:9317150] [PUBMED:14653992] [PUBMED:17081755] [PUBMED:12676083] [PUBMED:18216334] [PUBMED:19826000] [PUBMED:8702968] [PUBMED:11304531] [PUBMED:10973943] [PUBMED:11309380] [PUBMED:18586681] [PUBMED:15479449] [PUBMED:19097998] [PUBMED:16892055] [PUBMED:17244649] [PUBMED:8625410] [PUBMED:8497321] [PUBMED:15485841] [PUBMED:16407834] [PUBMED:11804587] [PUBMED:9867866] [PUBMED:10747870] [PUBMED:7600581] [PUBMED:12610628] [PUBMED:19435802] [PUBMED:15572110] [PUBMED:7592586] [PUBMED:11696321] [PUBMED:10559936]
Choline metabolism in cancer [NCBI:1059539] [KEGG:hsa05231] [PUBMED:23076158] [PUBMED:19264150] [PUBMED:16230400] [PUBMED:23350810] [PUBMED:22429397] [PUBMED:16432178] [PUBMED:19136975] [PUBMED:22089420] [PUBMED:14517341] [PUBMED:22921309] [PUBMED:19855431] [PUBMED:20528734] [PUBMED:19935796] [PUBMED:14523987] [PUBMED:21793073]
Endocytosis [NCBI:102279] [KEGG:hsa04144] [PUBMED:19696797] [PUBMED:19007773] [PUBMED:16203612] [PUBMED:15687999] [PUBMED:19924646] [PUBMED:15261671] [PUBMED:18647649] [PUBMED:19325624] [PUBMED:20110990] [PUBMED:22193161]
ErbB1 downstream signaling [NCBI:138057] [Pathway Interaction Database:erbb1_downstream_pathway] [PUBMED:1330321] [PUBMED:7939666] [PUBMED:9448004] [PUBMED:3497813] [PUBMED:7680434] [PUBMED:18567582] [PUBMED:12503606] [PUBMED:12183455] [PUBMED:8073291] [PUBMED:17563371] [PUBMED:8378775] [PUBMED:19219045] [PUBMED:1990291] [PUBMED:15550174] [PUBMED:16508002] [PUBMED:17881733] [PUBMED:11278353] [PUBMED:9889102] [PUBMED:14699061] [PUBMED:8248196] [PUBMED:8262053] [PUBMED:11319218] [PUBMED:19595761] [PUBMED:17360704] [PUBMED:15048123] [PUBMED:19341767] [PUBMED:9837959] [PUBMED:14993287] [PUBMED:19710016] [PUBMED:18516090] [PUBMED:9733714] [PUBMED:8052307] [PUBMED:10567369] [PUBMED:9335504] [PUBMED:9580112] [PUBMED:11018520] [PUBMED:10499589] [PUBMED:19706684] [PUBMED:8910287] [PUBMED:10469645] [PUBMED:11073940] [PUBMED:9315636] [PUBMED:2189103] [PUBMED:14765121] [PUBMED:14970219] [PUBMED:8332195] [PUBMED:16239230] [PUBMED:8621729] [PUBMED:11889038] [PUBMED:11029289] [PUBMED:11152283] [PUBMED:8071311] [PUBMED:12932319] [PUBMED:19541618] [PUBMED:2123453] [PUBMED:9384584] [PUBMED:8140422] [PUBMED:10644690] [PUBMED:18156174] [PUBMED:15718470] [PUBMED:12172553] [PUBMED:10082559] [PUBMED:17079732] [PUBMED:12446727] [PUBMED:9989263] [PUBMED:12551925] [PUBMED:10856237] [PUBMED:8013650] [PUBMED:7600581] [PUBMED:8688081] [PUBMED:8397445] [PUBMED:16135787] [PUBMED:7637810] [PUBMED:9438848] [PUBMED:12515821] [PUBMED:12881422] [PUBMED:9305638] [PUBMED:15284024] [PUBMED:3136398] [PUBMED:10597268] [PUBMED:10648629] [PUBMED:9790194] [PUBMED:9797479] [PUBMED:16093354] [PUBMED:7741752] [PUBMED:10891480] [PUBMED:17052213] [PUBMED:8221888] [PUBMED:9593664] [PUBMED:16892053] [PUBMED:8413226] [PUBMED:9407138] [PUBMED:9710644] [PUBMED:8248197] [PUBMED:12414794] [PUBMED:1653949] [PUBMED:12181570] [PUBMED:9550702] [PUBMED:12110590] [PUBMED:10400627] [PUBMED:9927426] [PUBMED:12242303] [PUBMED:10480933] [PUBMED:9665134] [PUBMED:11238956] [PUBMED:16984645] [PUBMED:7761091] [PUBMED:17322878] [PUBMED:12640115] [PUBMED:14963038] [PUBMED:17486115] [PUBMED:8503013] [PUBMED:16155590] [PUBMED:16628218] [PUBMED:1406636] [PUBMED:9430728] [PUBMED:19401591] [PUBMED:17053785] [PUBMED:7992057] [PUBMED:14609431] [PUBMED:9346240] [PUBMED:8626780] [PUBMED:8940018] [PUBMED:12454019] [PUBMED:10441128] [PUBMED:14747473] [PUBMED:11777939] [PUBMED:8614832] [PUBMED:8378774] [PUBMED:19121340] [PUBMED:18775988] [PUBMED:15039778] [PUBMED:9770464] [PUBMED:10567531] [PUBMED:8180183] [PUBMED:10675331] [PUBMED:1545823] [PUBMED:7958858] [PUBMED:11948693] [PUBMED:2109185] [PUBMED:8942998] [PUBMED:1637333] [PUBMED:14690430] [PUBMED:11134016] [PUBMED:12429840] [PUBMED:8621573] [PUBMED:7600582] [PUBMED:8226933] [PUBMED:10201527] [PUBMED:12832467] [PUBMED:3492494] [PUBMED:15034142] [PUBMED:9596579] [PUBMED:7889942] [PUBMED:8524316] [PUBMED:7731720] [PUBMED:8386592] [PUBMED:16407412] [PUBMED:6334806] [PUBMED:11703925] [PUBMED:11099046] [PUBMED:7876145] [PUBMED:14498832]
Ether lipid metabolism [NCBI:82990] [KEGG:hsa00565] [PUBMED:11015622] [PUBMED:11275267] [PUBMED:15788404]
Fc gamma R-mediated phagocytosis [NCBI:114228] [KEGG:hsa04666] [PUBMED:11304556] [PUBMED:11244038] [PUBMED:10755615] [PUBMED:17308335] [PUBMED:12821647] [PUBMED:15466916] [PUBMED:17050193] [PUBMED:11228151] [PUBMED:12488490] [PUBMED:10224668] [PUBMED:11708889] [PUBMED:9581795] [PUBMED:10586078] [PUBMED:9417101] [PUBMED:15485887] [PUBMED:18322649] [PUBMED:10577498] [PUBMED:10376013] [PUBMED:10601359] [PUBMED:9545263]
Fcgamma receptor (FCGR) dependent phagocytosis [NCBI:1269279] [REACTOME:R-HSA-2029480] [PUBMED:8541526] [PUBMED:12488490] [PUBMED:16413920] [PUBMED:17050193]
Glutamatergic synapse [NCBI:213818] [KEGG:hsa04724] [PUBMED:10481192] [PUBMED:11561058] [PUBMED:18425072] [PUBMED:17706608] [PUBMED:20055706] [PUBMED:19112153] [PUBMED:17663464] [PUBMED:19110202] [PUBMED:19559598] [PUBMED:9665875] [PUBMED:11672421] [PUBMED:18464791] [PUBMED:12399578] [PUBMED:14684436]
Glycerophospholipid biosynthesis [NCBI:1270054] [REACTOME:R-HSA-1483206] [PUBMED:21220505] [PUBMED:19703651] [PUBMED:20823909] [PUBMED:21683693] [PUBMED:21382416] [PUBMED:21704024]
Glycerophospholipid metabolism [NCBI:82989] [KEGG:hsa00564] [PUBMED:14663079] [PUBMED:15522832] [PUBMED:10938271] [PUBMED:10092508] [PUBMED:1649829] [PUBMED:10542045] [PUBMED:1512203] [PUBMED:12431977]
GnRH signaling pathway [NCBI:83091] [KEGG:hsa04912] [PUBMED:15080147] [PUBMED:15982836] [PUBMED:14596811] [PUBMED:15613448] [PUBMED:12943720] [PUBMED:10707049] [PUBMED:15350605] [PUBMED:12963732]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Innate Immune System [NCBI:1269203] [REACTOME:R-HSA-168249]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Neutrophil degranulation [NCBI:1457780] [REACTOME:R-HSA-6798695] [PUBMED:20338884] [PUBMED:1378856] [PUBMED:17627888] [PUBMED:23650620] [PUBMED:8692836]
Pancreatic cancer [NCBI:83108] [KEGG:hsa05212] [PUBMED:12079267] [PUBMED:14967450] [PUBMED:15774796] [PUBMED:10740269] [PUBMED:12946833] [PUBMED:16702400] [PUBMED:14586404] [PUBMED:15823750] [PUBMED:12648469] [PUBMED:11407945] [PUBMED:12459728] [PUBMED:14580692] [PUBMED:11707511] [PUBMED:12545153]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Phospholipase D signaling pathway [NCBI:1311074] [KEGG:hsa04072] [PUBMED:9310372] [PUBMED:9119890] [PUBMED:15310762] [PUBMED:18936782] [PUBMED:24990952] [PUBMED:14769825] [PUBMED:21936578] [PUBMED:10666319] [PUBMED:17210675] [PUBMED:19264150] [PUBMED:23076158] [PUBMED:17054901] [PUBMED:16622417] [PUBMED:10807766] [PUBMED:12217395] [PUBMED:11042115] [PUBMED:19815110] [PUBMED:24995811] [PUBMED:16143829] [PUBMED:8135758] [PUBMED:11991733] [PUBMED:19410013] [PUBMED:17245604]
Phospholipid metabolism [NCBI:1270053] [REACTOME:R-HSA-1483257] [PUBMED:9242906]
Ras signaling pathway [NCBI:868085] [KEGG:hsa04014] [PUBMED:23506953] [PUBMED:18437264] [PUBMED:15062121] [PUBMED:22189424] [PUBMED:22233291] [PUBMED:12778136] [PUBMED:11313946] [PUBMED:17428555] [PUBMED:19091743] [PUBMED:18568040] [PUBMED:20420946] [PUBMED:12217381] [PUBMED:14663478] [PUBMED:21686117] [PUBMED:12642680] [PUBMED:21196257] [PUBMED:16869784] [PUBMED:21111786] [PUBMED:16966426] [PUBMED:10712923] [PUBMED:22020205] [PUBMED:17384584] [PUBMED:15572660] [PUBMED:18413813]
Role of phospholipids in phagocytosis [NCBI:1269282] [REACTOME:R-HSA-2029485] [PUBMED:10224668] [PUBMED:20400677]
Sphingolipid signaling pathway [NCBI:1144995] [KEGG:hsa04071] [PUBMED:23919551] [PUBMED:21705677] [PUBMED:18675379] [PUBMED:20534702] [PUBMED:15999095] [PUBMED:16470226] [PUBMED:11001563] [PUBMED:17913601] [PUBMED:17161984] [PUBMED:22654878] [PUBMED:17438574] [PUBMED:18216770] [PUBMED:11418646] [PUBMED:10880336] [PUBMED:15451787] [PUBMED:25309325] [PUBMED:18403224]
Synthesis of PA [NCBI:1270055] [REACTOME:R-HSA-1483166] [PUBMED:21173190] [PUBMED:20705608] [PUBMED:18718904] [PUBMED:17170135] [PUBMED:12359733]
Synthesis of PG [NCBI:1270068] [REACTOME:R-HSA-1483148] [PUBMED:3718705] [PUBMED:7968268] [PUBMED:9407135]
cAMP signaling pathway [NCBI:1017634] [KEGG:hsa04024] [PUBMED:10880354] [PUBMED:9204709] [PUBMED:21693691] [PUBMED:24062645] [PUBMED:24450633] [PUBMED:21346730] [PUBMED:24613710] [PUBMED:21744067] [PUBMED:22082266] [PUBMED:16460276] [PUBMED:18176800] [PUBMED:14715909] [PUBMED:7688165] [PUBMED:24281338] [PUBMED:11117527] [PUBMED:16765984] [PUBMED:18323530] [PUBMED:18064650] [PUBMED:21852968] [PUBMED:11493633] [PUBMED:21212391] [PUBMED:15142747] [PUBMED:17077866] [PUBMED:19460777] [PUBMED:19874988] [PUBMED:16571352] [PUBMED:22022314]
mTOR signaling pathway [NCBI:83059] [KEGG:hsa04150] [NCBI:138001] [Pathway Interaction Database:mtor_4pathway] [PUBMED:17277771] [PUBMED:15341740] [PUBMED:12172553] [PUBMED:15718470] [PUBMED:14651849] [PUBMED:15268862] [PUBMED:15306821] [PUBMED:26046644] [PUBMED:12869586] [PUBMED:24556838] [PUBMED:17928295] [PUBMED:9427642] [PUBMED:18046414] [PUBMED:12912918] [PUBMED:16286006] [PUBMED:26658722] [PUBMED:24842496] [PUBMED:23465396] [PUBMED:17709744] [PUBMED:17599906] [PUBMED:16919458] [PUBMED:10364159] [PUBMED:15342917] [PUBMED:11500364] [PUBMED:19812304] [PUBMED:12482958] [PUBMED:11729323] [PUBMED:16962653] [PUBMED:18952604] [PUBMED:9465032] [PUBMED:1496022] [PUBMED:10567431] [PUBMED:19114562] [PUBMED:17510057] [PUBMED:18604198] [PUBMED:15545625] [PUBMED:11914378] [PUBMED:17461779] [PUBMED:9445476] [PUBMED:18497260] [PUBMED:12604610] [PUBMED:15071500] [PUBMED:18925875] [PUBMED:12906785] [PUBMED:11287630] [PUBMED:15004009] [PUBMED:16756488] [PUBMED:17043309] [PUBMED:18198340] [PUBMED:12820960] [PUBMED:12747827] [PUBMED:17053147] [PUBMED:15851026] [PUBMED:15467718] [PUBMED:18762023] [PUBMED:25242279] [PUBMED:24698685] [PUBMED:11175345] [PUBMED:27304501] [PUBMED:18411301] [PUBMED:11500365] [PUBMED:17693255] [PUBMED:23694989] [PUBMED:12231510] [PUBMED:19446321] [PUBMED:11418588] [PUBMED:19258318] [PUBMED:18439900] [PUBMED:19225151] [PUBMED:26185979] [PUBMED:10357815] [PUBMED:26269525] [PUBMED:23421405] [PUBMED:9271440] [PUBMED:16915281] [PUBMED:17141160] [PUBMED:15249583] [PUBMED:12912989] [PUBMED:27027448] [PUBMED:18423201] [PUBMED:19211835] [PUBMED:9204908] [PUBMED:26700098] [PUBMED:18566587] [PUBMED:17386266]
phospholipases [NCBI:142419] [BIOCYC:HUMAN_LIPASYN-PWY]