full name
kininogen 1

synonyms
BDK, BK, KNG, KNG1, ENSG00000113889

HGNC
HGNC:6383

Entrez Gene
Gene:3827

ENSEMBL
ENSG00000113889

location
chr: 3
start: 186435098
stop: 186462199
strand: +

OMIM
OMIM:612358: KNG1
OMIM:228960: [High molecular weight kininogen deficiency]
OMIM:228960: [Kininogen deficiency]

transcripts
NM_000893.3
NM_001166451.1
NM_001102416.2

pathways
Class A/1 (Rhodopsin-like receptors) [NCBI:1269545] [REACTOME:R-HSA-373076] [PUBMED:16902930]
Complement and coagulation cascades [NCBI:83073] [KEGG:hsa04610] [PUBMED:23564577] [PUBMED:25309880] [PUBMED:26082779] [PUBMED:23110467] [PUBMED:20027185] [PUBMED:25568220] [PUBMED:26324800] [PUBMED:25705421] [PUBMED:21811895] [PUBMED:23911436] [PUBMED:23564578] [PUBMED:24924409] [PUBMED:26489954] [PUBMED:17635716]
Formation of Fibrin Clot (Clotting Cascade) [NCBI:1269368] [REACTOME:R-HSA-140877] [PUBMED:1931959] [PUBMED:12524220]
G alpha (i) signalling events [NCBI:1269576] [REACTOME:R-HSA-418594] [PUBMED:3113327] [PUBMED:9278091]
G alpha (q) signalling events [NCBI:1269578] [REACTOME:R-HSA-416476] [PUBMED:19212139]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Gastrin-CREB signalling pathway via PKC and MAPK [NCBI:1269592] [REACTOME:R-HSA-881907] [PUBMED:10413847] [PUBMED:7491953] [PUBMED:17698287]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Intrinsic Pathway of Fibrin Clot Formation [NCBI:1269370] [REACTOME:R-HSA-140837] [PUBMED:1931959] [PUBMED:7598447] [PUBMED:12231555] [PUBMED:14691562]
Peptide ligand-binding receptors [NCBI:1269546] [REACTOME:R-HSA-375276] [PUBMED:14576899] [PUBMED:10977869] [PUBMED:16918325] [PUBMED:16847439] [PUBMED:17293890] [PUBMED:15734727] [PUBMED:12895595] [PUBMED:17604107] [PUBMED:14507421] [PUBMED:12432945] [PUBMED:16612131]
Platelet activation, signaling and aggregation [NCBI:1269350] [REACTOME:R-HSA-76002] [PUBMED:16543958] [PUBMED:8704248] [PUBMED:2018971] [PUBMED:1672265] [PUBMED:17059469] [PUBMED:12681240] [PUBMED:12411949] [PUBMED:11511514]
Platelet degranulation [NCBI:1269367] [REACTOME:R-HSA-114608] [PUBMED:14630798]
Response to elevated platelet cytosolic Ca2+ [NCBI:1269365] [REACTOME:R-HSA-76005] [PUBMED:8424766]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]
Syndecan-2-mediated signaling events [NCBI:138031] [Pathway Interaction Database:syndecan_2_pathway] [PUBMED:17623663] [PUBMED:11373281] [PUBMED:16357320] [PUBMED:12507425] [PUBMED:16945929] [PUBMED:14976204] [PUBMED:10772816] [PUBMED:10843988] [PUBMED:8528141] [PUBMED:15936998] [PUBMED:10734053] [PUBMED:11179419] [PUBMED:9660868] [PUBMED:16198615] [PUBMED:9660869] [PUBMED:15752734] [PUBMED:10446183] [PUBMED:11580899] [PUBMED:17548511] [PUBMED:11931647] [PUBMED:16139226] [PUBMED:16008343] [PUBMED:14527339] [PUBMED:16997272] [PUBMED:10639336] [PUBMED:16440330] [PUBMED:11018053] [PUBMED:10704377] [PUBMED:9244383] [PUBMED:12860416]
amb2 Integrin signaling [NCBI:137945] [Pathway Interaction Database:amb2_neutrophils_pathway] [PUBMED:15004192] [PUBMED:16260637] [PUBMED:8874219] [PUBMED:12736251] [PUBMED:12824186] [PUBMED:17202407] [PUBMED:15458976] [PUBMED:12208882] [PUBMED:10985384] [PUBMED:8598477] [PUBMED:8157977] [PUBMED:14530377] [PUBMED:16567504] [PUBMED:7836767] [PUBMED:17003381] [PUBMED:10899906] [PUBMED:15741160] [PUBMED:9920836] [PUBMED:12941957] [PUBMED:12773513] [PUBMED:15283855] [PUBMED:16854414] [PUBMED:15217824] [PUBMED:15090462] [PUBMED:14769799] [PUBMED:16905120] [PUBMED:9831565] [PUBMED:12194823] [PUBMED:17268551] [PUBMED:17133598] [PUBMED:15153528] [PUBMED:11418469] [PUBMED:14623906] [PUBMED:12036876] [PUBMED:16391519] [PUBMED:15304494] [PUBMED:16093349] [PUBMED:16403785]