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Genes
TLR1
Gene - TLR1
full name
toll like receptor 1
synonyms
CD281, rsc786, TIL, TIL., TLR1, ENSG00000174125
HGNC
HGNC:11847
Entrez Gene
Gene:7096
ENSEMBL
ENSG00000174125
location
chr: 4
start: 38797876
stop: 38806814
strand: -
OMIM
OMIM:601194
: TLR1
OMIM:613223
: {Leprosy, protection against}
OMIM:613223
: {Leprosy, susceptibility to, 5}
transcripts
NM_003263.3
pathways
Activated TLR4 signalling
[NCBI:1269236]
[REACTOME:R-HSA-166054]
[PUBMED:15276183]
[PUBMED:15588429]
[PUBMED:15845500]
[PUBMED:15596121]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Antigen processing-Cross presentation
[NCBI:1269195]
[REACTOME:R-HSA-1236975]
[PUBMED:17157489]
[PUBMED:20171863]
[PUBMED:16181333]
[PUBMED:15761154]
[PUBMED:16181335]
[PUBMED:19218463]
Antimicrobial peptides
[NCBI:1457777]
[REACTOME:R-HSA-6803157]
[PUBMED:12615953]
[PUBMED:24287494]
Beta defensins
[NCBI:1269267]
[REACTOME:R-HSA-1461957]
[PUBMED:16710608]
Class I MHC mediated antigen processing & presentation
[NCBI:1269192]
[REACTOME:R-HSA-983169]
[PUBMED:8717519]
[PUBMED:17145306]
[PUBMED:18926908]
[PUBMED:17055423]
[PUBMED:12495737]
[PUBMED:18641646]
[PUBMED:18243674]
Defensins
[NCBI:1269265]
[REACTOME:R-HSA-1461973]
[PUBMED:15372083]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases associated with the TLR signaling cascade
[NCBI:1269157]
[REACTOME:R-HSA-5602358]
[PUBMED:23622315]
[PUBMED:21734245]
[PUBMED:22610250]
[PUBMED:16176658]
Diseases of Immune System
[NCBI:1269156]
[REACTOME:R-HSA-5260271]
[PUBMED:24795713]
[PUBMED:22165913]
ER-Phagosome pathway
[NCBI:1269197]
[REACTOME:R-HSA-1236974]
[PUBMED:16213220]
[PUBMED:20171863]
[PUBMED:14508490]
[PUBMED:17027300]
[PUBMED:14561893]
[PUBMED:15845646]
[PUBMED:22915823]
[PUBMED:18006660]
[PUBMED:14508489]
[PUBMED:12151002]
[PUBMED:15728715]
IRAK4 deficiency (TLR2/4)
[NCBI:1269158]
[REACTOME:R-HSA-5603041]
[PUBMED:18669862]
[PUBMED:12637671]
[PUBMED:24316379]
[PUBMED:15069402]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
MyD88 deficiency (TLR2/4)
[NCBI:1269160]
[REACTOME:R-HSA-5602498]
[PUBMED:18669862]
[PUBMED:24316379]
[PUBMED:15069402]
MyD88:Mal cascade initiated on plasma membrane
[NCBI:1269237]
[REACTOME:R-HSA-166058]
[PUBMED:15276183]
Regulation of TLR by endogenous ligand
[NCBI:1427857]
[REACTOME:R-HSA-5686938]
[PUBMED:25391648]
[PUBMED:20706656]
[PUBMED:20629986]
[PUBMED:20179153]
Toll Like Receptor 2 (TLR2) Cascade
[NCBI:1269238]
[REACTOME:R-HSA-181438]
[PUBMED:10820283]
Toll Like Receptor 4 (TLR4) Cascade
[NCBI:1269234]
[REACTOME:R-HSA-166016]
Toll Like Receptor TLR1:TLR2 Cascade
[NCBI:1269239]
[REACTOME:R-HSA-168179]
[PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade
[NCBI:1269240]
[REACTOME:R-HSA-168188]
[PUBMED:14977973]
Toll-Like Receptors Cascades
[NCBI:1269204]
[REACTOME:R-HSA-168898]
[PUBMED:15950447]
[PUBMED:12893815]
[PUBMED:15976490]
[PUBMED:15585605]
[PUBMED:14751757]
Toll-like receptor signaling pathway
[NCBI:83076]
[KEGG:hsa04620]
[PUBMED:16924467]
[PUBMED:17395581]
[PUBMED:17637696]
[PUBMED:12734364]
[PUBMED:17507094]
[PUBMED:14698224]
[PUBMED:11101877]
[PUBMED:16497588]
[PUBMED:14751764]
[PUBMED:17275323]
[PUBMED:17457343]
[PUBMED:16932750]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]