full name
platelet factor 4

synonyms
CXCL4, PF-4, SCYB4, PF4, ENSG00000163737

HGNC
HGNC:8861

Entrez Gene
Gene:5196

ENSEMBL
ENSG00000163737

location
chr: 4
start: 74846542
stop: 74847841
strand: -

transcripts
NM_002619.3

pathways
CXCR3-mediated signaling events [NCBI:138011] [Pathway Interaction Database:cxcr3pathway] [PUBMED:15528361] [PUBMED:16210647] [PUBMED:9541591] [PUBMED:16368892] [PUBMED:9660793] [PUBMED:17289675] [PUBMED:16467404] [PUBMED:18291705] [PUBMED:18375741] [PUBMED:15150261] [PUBMED:9625760] [PUBMED:18174362] [PUBMED:11554781] [PUBMED:12750173] [PUBMED:12782716] [PUBMED:11136732] [PUBMED:11739530] [PUBMED:18292502]
Cell surface interactions at the vascular wall [NCBI:1269373] [REACTOME:R-HSA-202733] [PUBMED:17525755] [PUBMED:11282294] [PUBMED:10798271] [PUBMED:8578462] [PUBMED:14615387] [PUBMED:16115029]
Chemokine receptors bind chemokines [NCBI:1269547] [REACTOME:R-HSA-380108] [PUBMED:15578986] [PUBMED:11544102] [PUBMED:10807766]
Chemokine signaling pathway [NCBI:99051] [KEGG:hsa04062] [PUBMED:17371236] [PUBMED:19159344] [PUBMED:17169327] [PUBMED:10852130] [PUBMED:9765254] [PUBMED:15771581] [PUBMED:14607270] [PUBMED:18662984] [PUBMED:12495636] [PUBMED:15803148] [PUBMED:15046611] [PUBMED:12069927] [PUBMED:18711432] [PUBMED:17675482] [PUBMED:16144840] [PUBMED:17496928] [PUBMED:17537990] [PUBMED:11872087] [PUBMED:12051620] [PUBMED:14625285] [PUBMED:8576262] [PUBMED:11244042]
Class A/1 (Rhodopsin-like receptors) [NCBI:1269545] [REACTOME:R-HSA-373076] [PUBMED:16902930]
Common Pathway of Fibrin Clot Formation [NCBI:1269371] [REACTOME:R-HSA-140875] [PUBMED:1931959]
Cytokine-cytokine receptor interaction [NCBI:83051] [KEGG:hsa04060] [PUBMED:11071910] [PUBMED:12072446] [PUBMED:7791754] [PUBMED:15032600] [PUBMED:12651226] [PUBMED:11252892] [PUBMED:11796220] [PUBMED:11312110] [PUBMED:9862719] [PUBMED:12421671] [PUBMED:12039028] [PUBMED:9759503] [PUBMED:9395284] [PUBMED:11166270] [PUBMED:10714678] [PUBMED:12651221]
Formation of Fibrin Clot (Clotting Cascade) [NCBI:1269368] [REACTOME:R-HSA-140877] [PUBMED:1931959] [PUBMED:12524220]
G alpha (i) signalling events [NCBI:1269576] [REACTOME:R-HSA-418594] [PUBMED:3113327] [PUBMED:9278091]
GPCR downstream signaling [NCBI:1269574] [REACTOME:R-HSA-388396] [PUBMED:12040175]
GPCR ligand binding [NCBI:1269544] [REACTOME:R-HSA-500792] [PUBMED:15251227]
Hemostasis [NCBI:1269340] [REACTOME:R-HSA-109582]
Peptide ligand-binding receptors [NCBI:1269546] [REACTOME:R-HSA-375276] [PUBMED:14576899] [PUBMED:10977869] [PUBMED:16918325] [PUBMED:16847439] [PUBMED:17293890] [PUBMED:15734727] [PUBMED:12895595] [PUBMED:17604107] [PUBMED:14507421] [PUBMED:12432945] [PUBMED:16612131]
Platelet activation, signaling and aggregation [NCBI:1269350] [REACTOME:R-HSA-76002] [PUBMED:16543958] [PUBMED:8704248] [PUBMED:2018971] [PUBMED:1672265] [PUBMED:17059469] [PUBMED:12681240] [PUBMED:12411949] [PUBMED:11511514]
Platelet degranulation [NCBI:1269367] [REACTOME:R-HSA-114608] [PUBMED:14630798]
Response to elevated platelet cytosolic Ca2+ [NCBI:1269365] [REACTOME:R-HSA-76005] [PUBMED:8424766]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by GPCR [NCBI:1269543] [REACTOME:R-HSA-372790] [PUBMED:16902930] [PUBMED:10202136] [PUBMED:18043707]