Logo
full name
solute carrier family 2 member 1

synonyms
DYT17, DYT18, DYT9, EIG12, GLUT, GLUT1, GLUT1DS, HTLVR, PED, SLC2A1, ENSG00000117394

HGNC
HGNC:11005

Entrez Gene
Gene:6513

ENSEMBL
ENSG00000117394

location
chr: 1
start: 43391046
stop: 43424847
strand: -

OMIM
OMIM:138140: SLC2A1 (Autosomal dominant inheritance)
OMIM:601042: Dystonia 9
OMIM:606777: GLUT1 deficiency syndrome 1, infantile onset, severe
OMIM:612126: GLUT1 deficiency syndrome 2, childhood onset
OMIM:608885: Stomatin-deficient cryohydrocytosis with neurologic defects
OMIM:614847: {Epilepsy, idiopathic generalized, susceptibility to, 12}

transcripts
NM_006516.2

pathways
Adipocytokine signaling pathway [NCBI:83093] [KEGG:hsa04920] [PUBMED:12829246] [PUBMED:10905472] [PUBMED:15980064] [PUBMED:12754525] [PUBMED:12368907] [PUBMED:11557972] [PUBMED:15856064] [PUBMED:10766253] [PUBMED:9671776] [PUBMED:14679176] [PUBMED:15733744] [PUBMED:15058305] [PUBMED:11479627] [PUBMED:14716305]
Bile secretion [NCBI:193146] [KEGG:hsa04976] [PUBMED:11826283] [PUBMED:19273385] [PUBMED:12663868] [PUBMED:15975683] [PUBMED:18837079] [PUBMED:18377365] [PUBMED:16706681] [PUBMED:12483266] [PUBMED:14659471] [PUBMED:18670431] [PUBMED:19273238] [PUBMED:18668439] [PUBMED:18371245] [PUBMED:11316487] [PUBMED:18081658] [PUBMED:19482594] [PUBMED:15758646] [PUBMED:17404808] [PUBMED:10728790] [PUBMED:14999673] [PUBMED:20103563]
Central carbon metabolism in cancer [NCBI:1059538] [KEGG:hsa05230] [PUBMED:16982728] [PUBMED:21127244] [PUBMED:22156302] [PUBMED:22349059] [PUBMED:21801601] [PUBMED:15916903] [PUBMED:24113830] [PUBMED:23018234] [PUBMED:22237205] [PUBMED:23897900] [PUBMED:20520704] [PUBMED:18177721] [PUBMED:24398961] [PUBMED:18538731] [PUBMED:24079832] [PUBMED:19460998] [PUBMED:22101401] [PUBMED:22750268] [PUBMED:22307140] [PUBMED:23071355] [PUBMED:21258394] [PUBMED:23279446] [PUBMED:21340684] [PUBMED:19270154] [PUBMED:18766298] [PUBMED:21508971] [PUBMED:24738035]
Facilitative Na+-independent glucose transporters [NCBI:1269924] [REACTOME:R-HSA-428790] [PUBMED:18660845] [PUBMED:11780753] [PUBMED:12568659]
Glucagon signaling pathway [NCBI:1144996] [KEGG:hsa04922] [PUBMED:20735177] [PUBMED:19912989] [PUBMED:21941300] [PUBMED:22249520] [PUBMED:18669612] [PUBMED:16601267] [PUBMED:12626323] [PUBMED:24692138] [PUBMED:16479585] [PUBMED:21346730] [PUBMED:22495310] [PUBMED:22004992] [PUBMED:22550228] [PUBMED:24238363] [PUBMED:22503562] [PUBMED:24393785] [PUBMED:22796337]
Glucose transport [NCBI:1269921] [REACTOME:R-HSA-70153] [PUBMED:11780753]
Glycolysis and Gluconeogenesis [NCBI:198814] [WikiPathways:WP534] [PUBMED:22628558]
HIF-1 signaling pathway [NCBI:695200] [KEGG:hsa04066] [PUBMED:11902584] [PUBMED:22205687] [PUBMED:15031665] [PUBMED:19364912] [PUBMED:18259201] [PUBMED:18505681] [PUBMED:15448722] [PUBMED:19147540] [PUBMED:20836033] [PUBMED:19861159] [PUBMED:22562152] [PUBMED:20965423] [PUBMED:20679415] [PUBMED:16234508] [PUBMED:17955264]
HIF-1-alpha transcription factor network [NCBI:138045] [Pathway Interaction Database:hif1_tfpathway] [PUBMED:9242677] [PUBMED:9038135] [PUBMED:11707426] [PUBMED:15310764] [PUBMED:8663540] [PUBMED:11278891] [PUBMED:8816435] [PUBMED:15235127] [PUBMED:15312748] [PUBMED:14612449] [PUBMED:9822602] [PUBMED:9632793] [PUBMED:12615703] [PUBMED:8408001] [PUBMED:11342587] [PUBMED:15104534] [PUBMED:10594042] [PUBMED:15252039] [PUBMED:13679920] [PUBMED:15199161] [PUBMED:12354771] [PUBMED:15235597] [PUBMED:9436976] [PUBMED:8955077] [PUBMED:10446188] [PUBMED:12370277] [PUBMED:12879018] [PUBMED:15466858] [PUBMED:11823643] [PUBMED:8089148] [PUBMED:14645546] [PUBMED:9486205] [PUBMED:11708773] [PUBMED:9887100] [PUBMED:15280364] [PUBMED:14742449] [PUBMED:10777486] [PUBMED:8917528] [PUBMED:15611046] [PUBMED:12067980] [PUBMED:15611089] [PUBMED:10353251] [PUBMED:9707622] [PUBMED:15563275] [PUBMED:12042299] [PUBMED:12228247] [PUBMED:15044468] [PUBMED:11877282] [PUBMED:12215445]
HIF-2-alpha transcription factor network [NCBI:137956] [Pathway Interaction Database:hif2pathway] [PUBMED:15039136] [PUBMED:19352007] [PUBMED:10671489] [PUBMED:11983697] [PUBMED:11823643] [PUBMED:17097563] [PUBMED:17873906] [PUBMED:18356544] [PUBMED:12080085] [PUBMED:19541651] [PUBMED:16510872] [PUBMED:11292862] [PUBMED:15247232] [PUBMED:19498162] [PUBMED:10353251] [PUBMED:19204094] [PUBMED:9079689] [PUBMED:17322295] [PUBMED:17804822] [PUBMED:15592504] [PUBMED:18434321] [PUBMED:12464608] [PUBMED:9113979] [PUBMED:10878807] [PUBMED:16611993] [PUBMED:15192019] [PUBMED:9000051] [PUBMED:10823831] [PUBMED:16740701] [PUBMED:18625704] [PUBMED:17324924]
HTLV-I infection [NCBI:373901] [KEGG:hsa05166] [PUBMED:16436385] [PUBMED:17446673] [PUBMED:14686485] [PUBMED:19861996] [PUBMED:16155605] [PUBMED:16155602] [PUBMED:12910251] [PUBMED:18702816] [PUBMED:11244044] [PUBMED:15569630] [PUBMED:21114861] [PUBMED:17384582] [PUBMED:16155608] [PUBMED:16155611] [PUBMED:10602469] [PUBMED:9325311] [PUBMED:19014483] [PUBMED:19092975] [PUBMED:11325603] [PUBMED:16036567]
Hexose transport [NCBI:1269920] [REACTOME:R-HSA-189200] [PUBMED:16186415] [PUBMED:15546855]
IL-3 Signaling Pathway [NCBI:198881] [WikiPathways:WP286]
Insulin Signaling [NCBI:198845] [WikiPathways:WP481] [PUBMED:11742412] [PUBMED:1890850] [PUBMED:11282018]
Insulin resistance [NCBI:1272486] [KEGG:hsa04931] [PUBMED:20466550] [PUBMED:17130651] [PUBMED:16364488] [PUBMED:12765939] [PUBMED:15166380] [PUBMED:7666792] [PUBMED:10923637] [PUBMED:23647930] [PUBMED:16756496] [PUBMED:17141630] [PUBMED:18309108] [PUBMED:20526383] [PUBMED:22675355] [PUBMED:16186396] [PUBMED:15107844] [PUBMED:22360800] [PUBMED:9886945] [PUBMED:8048519] [PUBMED:22677645]
Insulin secretion [NCBI:777534] [KEGG:hsa04911] [PUBMED:9715374] [PUBMED:20055708] [PUBMED:10605628] [PUBMED:17306374] [PUBMED:9914469] [PUBMED:14693691] [PUBMED:19817784] [PUBMED:19074620] [PUBMED:15655710] [PUBMED:17084085] [PUBMED:20551594] [PUBMED:19036624] [PUBMED:22970724] [PUBMED:20225132] [PUBMED:22974438] [PUBMED:19817800] [PUBMED:21934040] [PUBMED:15271645] [PUBMED:19660440] [PUBMED:11522660]
Integration of energy metabolism [NCBI:1270101] [REACTOME:R-HSA-163685] [PUBMED:15509864] [PUBMED:12721358] [PUBMED:12626323]
Lactose synthesis [NCBI:1269968] [REACTOME:R-HSA-5653890] [PUBMED:806951]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Metabolism of vitamins and cofactors [NCBI:1270144] [REACTOME:R-HSA-196854]
Metabolism of water-soluble vitamins and cofactors [NCBI:1270145] [REACTOME:R-HSA-196849]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:16001072] [PUBMED:16699851] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:15156182] [PUBMED:15310786] [PUBMED:21193867] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:12951584] [PUBMED:11071626] [PUBMED:9834202] [PUBMED:15721476] [PUBMED:11895903] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:11477132] [PUBMED:15724144] [PUBMED:10647931] [PUBMED:16700615] [PUBMED:11527574] [PUBMED:16339096] [PUBMED:12545153] [PUBMED:15942304] [PUBMED:16352814] [PUBMED:15656799] [PUBMED:10740269] [PUBMED:16881963] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:17287871] [PUBMED:15557758] [PUBMED:10944551] [PUBMED:11170304] [PUBMED:12154354] [PUBMED:15639402] [PUBMED:16326109] [PUBMED:11276000] [PUBMED:15573119] [PUBMED:15625120] [PUBMED:15109562] [PUBMED:11160144] [PUBMED:15611513] [PUBMED:15349822] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:16551846] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:11130178] [PUBMED:14580692] [PUBMED:14634372] [PUBMED:12407699] [PUBMED:12588368] [PUBMED:15009714] [PUBMED:16001050] [PUBMED:16112428] [PUBMED:9643506] [PUBMED:15468170] [PUBMED:16248975] [PUBMED:12946833] [PUBMED:11057895] [PUBMED:11559746] [PUBMED:16306523] [PUBMED:16064138] [PUBMED:15479695] [PUBMED:11900250] [PUBMED:9422516] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:12894244] [PUBMED:11103787] [PUBMED:12878745] [PUBMED:16702400] [PUBMED:14685170] [PUBMED:16189154] [PUBMED:11720739] [PUBMED:15122209] [PUBMED:11078609] [PUBMED:12243753] [PUBMED:14982876] [PUBMED:16642045] [PUBMED:12563308] [PUBMED:11407945] [PUBMED:14586404] [PUBMED:15270885] [PUBMED:16095998] [PUBMED:15948971] [PUBMED:16484590] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11459867] [PUBMED:10505543] [PUBMED:15746962] [PUBMED:16146838] [PUBMED:15947972] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:15841168] [PUBMED:11463388] [PUBMED:16474624] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:14556242] [PUBMED:10453277] [PUBMED:11721960] [PUBMED:11905738] [PUBMED:10403855] [PUBMED:12741677] [PUBMED:12616528] [PUBMED:15823750] [PUBMED:12737309] [PUBMED:14695152] [PUBMED:16750612] [PUBMED:11807782] [PUBMED:12351585] [PUBMED:14737121] [PUBMED:12801837] [PUBMED:11431710] [PUBMED:11165748] [PUBMED:11750244] [PUBMED:11224709] [PUBMED:16110317] [PUBMED:16508724] [PUBMED:15948711] [PUBMED:16870043] [PUBMED:7585656] [PUBMED:12379883] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:14747944] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:17158541] [PUBMED:12468433] [PUBMED:16042571] [PUBMED:16557281] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:16189702] [PUBMED:8069858] [PUBMED:12951588] [PUBMED:16242838] [PUBMED:15082523] [PUBMED:17211469] [PUBMED:12711111] [PUBMED:15284264] [PUBMED:11223406] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:16946003] [PUBMED:12762887] [PUBMED:16054233] [PUBMED:16822996] [PUBMED:17554387] [PUBMED:17028294]
Regulation of insulin secretion [NCBI:1270102] [REACTOME:R-HSA-422356] [PUBMED:18200017] [PUBMED:16321791] [PUBMED:16556766] [PUBMED:11815463] [PUBMED:11078440]
Renal cell carcinoma [NCBI:83107] [KEGG:hsa05211] [PUBMED:12351585] [PUBMED:16339096] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15611513] [PUBMED:14685170] [PUBMED:15122209] [PUBMED:17211469]
SLC-mediated transmembrane transport [NCBI:1269907] [REACTOME:R-HSA-425407] [PUBMED:19164095] [PUBMED:14624363]
Thyroid hormone signaling pathway [NCBI:946598] [KEGG:hsa04919] [PUBMED:17983645] [PUBMED:20005976] [PUBMED:15345678] [PUBMED:16951130] [PUBMED:18329679] [PUBMED:20051527] [PUBMED:16214361] [PUBMED:17574003] [PUBMED:19716314] [PUBMED:19755667] [PUBMED:20868274] [PUBMED:21835053] [PUBMED:19295177] [PUBMED:16051672] [PUBMED:22484490] [PUBMED:23021374]
Transmembrane transport of small molecules [NCBI:1269903] [REACTOME:R-HSA-382551]
Transport of glucose and other sugars, bile salts and organic acids, metal ions and amine compounds [NCBI:1269923] [REACTOME:R-HSA-425366] [PUBMED:12811562] [PUBMED:12748858] [PUBMED:12750891] [PUBMED:19164095]
Validated targets of C-MYC transcriptional activation [NCBI:169351] [Pathway Interaction Database:myc_activpathway] [PUBMED:18987359] [PUBMED:16537449] [PUBMED:8356088] [PUBMED:19020761] [PUBMED:10688915] [PUBMED:16508012] [PUBMED:9924025] [PUBMED:1562593] [PUBMED:12091391] [PUBMED:10823814] [PUBMED:17967894] [PUBMED:15723053] [PUBMED:12637527] [PUBMED:15774466] [PUBMED:20173740] [PUBMED:12776737] [PUBMED:12011429] [PUBMED:10022128] [PUBMED:11511539] [PUBMED:11522645] [PUBMED:12138190] [PUBMED:17599065] [PUBMED:6438521] [PUBMED:19745813] [PUBMED:12177005] [PUBMED:18042711] [PUBMED:10779353] [PUBMED:1989881] [PUBMED:12529648] [PUBMED:10891489] [PUBMED:8196628] [PUBMED:9192621] [PUBMED:11103792] [PUBMED:8934531] [PUBMED:16172399] [PUBMED:8297793] [PUBMED:12776177] [PUBMED:8494784] [PUBMED:9811896] [PUBMED:8861962] [PUBMED:17088530] [PUBMED:1340466] [PUBMED:10508165] [PUBMED:16423995] [PUBMED:8327497] [PUBMED:17822678] [PUBMED:12816956] [PUBMED:11598121] [PUBMED:12695333] [PUBMED:19211792] [PUBMED:11673469] [PUBMED:14724288] [PUBMED:11511535] [PUBMED:17848523] [PUBMED:9869632] [PUBMED:11909865] [PUBMED:15944709] [PUBMED:9212167] [PUBMED:10606642] [PUBMED:16287840] [PUBMED:18978814] [PUBMED:11604407] [PUBMED:17643117] [PUBMED:8700224] [PUBMED:9178906] [PUBMED:16269333] [PUBMED:15723054] [PUBMED:15282543] [PUBMED:17170079] [PUBMED:18593934] [PUBMED:18408012]
Vitamin C (ascorbate) metabolism [NCBI:1270146] [REACTOME:R-HSA-196836] [PUBMED:17222174]