full name
synuclein alpha

synonyms
NACP, PARK1, PARK4, PD1, SNCA, ENSG00000145335

HGNC
HGNC:11138

Entrez Gene
Gene:6622

ENSEMBL
ENSG00000145335

location
chr: 4
start: 90645250
stop: 90759447
strand: -

OMIM
OMIM:163890: SNCA (Autosomal dominant inheritance)
OMIM:127750: Dementia, Lewy body
OMIM:168601: Parkinson disease 1
OMIM:605543: Parkinson disease 4

transcripts
NM_001146055.1
NM_000345.3
NM_007308.2
NM_001146054.1

pathways
Alpha-synuclein signaling [NCBI:137913] [Pathway Interaction Database:alphasynuclein_pathway] [PUBMED:12551928] [PUBMED:15671022] [PUBMED:12887682] [PUBMED:14991825] [PUBMED:11431533] [PUBMED:11588587] [PUBMED:16030137] [PUBMED:15845543] [PUBMED:11590439] [PUBMED:12096713] [PUBMED:11687285] [PUBMED:15978696] [PUBMED:10407019] [PUBMED:11078745] [PUBMED:16403519] [PUBMED:14985429] [PUBMED:14645218] [PUBMED:12787066] [PUBMED:11292651] [PUBMED:12421356] [PUBMED:15944382] [PUBMED:10567343] [PUBMED:11744621] [PUBMED:15935068] [PUBMED:12928483] [PUBMED:11821392] [PUBMED:10852916]
Alzheimer's disease [NCBI:83097] [KEGG:hsa05010] [PUBMED:18782350] [PUBMED:18035450] [PUBMED:15177383] [PUBMED:10527810] [PUBMED:15363492] [PUBMED:16677790] [PUBMED:15295589] [PUBMED:17055782] [PUBMED:15864339] [PUBMED:15750290] [PUBMED:18675468] [PUBMED:15232608] [PUBMED:9848086] [PUBMED:11484003] [PUBMED:10830966] [PUBMED:16529745] [PUBMED:17568632]
Amyloid fiber formation [NCBI:1269169] [REACTOME:R-HSA-977225] [PUBMED:16302959]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
Parkinson's disease [NCBI:83098] [KEGG:hsa05012] [PUBMED:15767499] [PUBMED:12461550] [PUBMED:21811441] [PUBMED:17911161] [PUBMED:15525720] [PUBMED:16022590] [PUBMED:12971891] [PUBMED:15681812] [PUBMED:16495942] [PUBMED:11331916] [PUBMED:18426756] [PUBMED:16278972] [PUBMED:18680555] [PUBMED:12938733] [PUBMED:15770999] [PUBMED:12728264] [PUBMED:15054086] [PUBMED:20236221] [PUBMED:22927178]