full name
3'-phosphoadenosine 5'-phosphosulfate synthase 1

synonyms
ATPSK1, PAPSS, SK1, PAPSS1, ENSG00000138801

HGNC
HGNC:8603

Entrez Gene
Gene:9061

ENSEMBL
ENSG00000138801

location
chr: 4
start: 108534822
stop: 108641419
strand: -

transcripts
NM_005443.4

pathways
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cytosolic sulfonation of small molecules [NCBI:1270210] [REACTOME:R-HSA-156584] [PUBMED:10503886] [PUBMED:9034160] [PUBMED:12372849]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Glycosaminoglycan metabolism [NCBI:1269972] [REACTOME:R-HSA-1630316] [PUBMED:18201392] [PUBMED:20301236] [PUBMED:820626]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of amino acids and derivatives [NCBI:1270158] [REACTOME:R-HSA-71291]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Metabolism of ingested H2SeO4 and H2SeO3 into H2Se [NCBI:1339154] [REACTOME:R-HSA-2408550] [PUBMED:19406206]
Oncogenic MAPK signaling [NCBI:1457781] [REACTOME:R-HSA-6802957] [PUBMED:25907612] [PUBMED:24651010] [PUBMED:24202393] [PUBMED:25435214] [PUBMED:21993244] [PUBMED:24814062] [PUBMED:22589270]
Phase II conjugation [NCBI:1270207] [REACTOME:R-HSA-156580] [PUBMED:11805192]
Purine metabolism [NCBI:82944] [KEGG:hsa00230] [NCBI:1270134] [REACTOME:R-HSA-73847] [PUBMED:4620886] [PUBMED:10986234] [PUBMED:10601204]
Selenoamino acid metabolism [NCBI:1339149] [REACTOME:R-HSA-2408522] [PUBMED:20812787]
Selenocompound metabolism [NCBI:82969] [KEGG:hsa00450] [PUBMED:20383543] [PUBMED:21190829] [PUBMED:19051051] [PUBMED:11782468] [PUBMED:17451884]
Signaling by BRAF and RAF fusions [NCBI:1457786] [REACTOME:R-HSA-6802952] [PUBMED:18974108] [PUBMED:24135138] [PUBMED:22745804] [PUBMED:25907612] [PUBMED:20526349] [PUBMED:15630448] [PUBMED:25204415] [PUBMED:24345920] [PUBMED:21424530] [PUBMED:23583981]
Sulfur metabolism [NCBI:83026] [KEGG:hsa00920] [PUBMED:18929068] [PUBMED:22092713] [PUBMED:16452431] [PUBMED:22633058] [PUBMED:21833341] [PUBMED:20143161] [PUBMED:22982583] [PUBMED:9695921]
Transport and synthesis of PAPS [NCBI:1269976] [REACTOME:R-HSA-174362] [PUBMED:13575436] [PUBMED:9668121] [PUBMED:9771708] [PUBMED:9576487]
sulfate activation for sulfonation [NCBI:142427] [BIOCYC:HUMAN_PWY-5340] [PUBMED:13575436] [PUBMED:11773860] [PUBMED:9576487] [PUBMED:13851709] [PUBMED:6107250] [PUBMED:9668121] [PUBMED:8180221]