full name
cytochrome P450 family 2 subfamily U member 1

synonyms
P450TEC, SPG49, SPG56, CYP2U1, ENSG00000155016

HGNC
HGNC:20582

Entrez Gene
Gene:113612

ENSEMBL
ENSG00000155016

location
chr: 4
start: 108852716
stop: 108874617
strand: +

OMIM
OMIM:610670: CYP2U1 (Autosomal recessive inheritance)
OMIM:615030: Spastic paraplegia 56, autosomal recessive

transcripts
NM_183075.2

pathways
Arachidonic acid metabolism [NCBI:82991] [KEGG:hsa00590] [NCBI:1270087] [REACTOME:R-HSA-2142753] [PUBMED:14622984] [PUBMED:15292194] [PUBMED:10908295] [PUBMED:15205388] [PUBMED:9812980] [PUBMED:14660610] [PUBMED:11328810] [PUBMED:14636671] [PUBMED:14626496] [PUBMED:11679404] [PUBMED:19244215]
Biological oxidations [NCBI:1270189] [REACTOME:R-HSA-211859]
Cytochrome P450 - arranged by substrate type [NCBI:1270191] [REACTOME:R-HSA-211897] [PUBMED:16584116] [PUBMED:15102545] [PUBMED:12369887]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of lipids and lipoproteins [NCBI:1270001] [REACTOME:R-HSA-556833]
Miscellaneous substrates [NCBI:1270200] [REACTOME:R-HSA-211958] [PUBMED:17786643] [PUBMED:15102545] [PUBMED:16126164]
Phase 1 - Functionalization of compounds [NCBI:1270190] [REACTOME:R-HSA-211945] [PUBMED:12369887] [PUBMED:17125408] [PUBMED:16584116]
Synthesis of (16-20)-hydroxyeicosatetraenoic acids (HETE) [NCBI:1270095] [REACTOME:R-HSA-2142816] [PUBMED:19244215] [PUBMED:10681399]
acetone degradation I (to methylglyoxal) [NCBI:545352] [BIOCYC:HUMAN_PWY-5451] [PUBMED:6389978] [PUBMED:10424765] [PUBMED:6706932] [PUBMED:963888] [PUBMED:12726989] [PUBMED:4624981] [PUBMED:3943633] [PUBMED:4055750] [PUBMED:4358273] [PUBMED:2806080]
bupropion degradation [NCBI:142436] [BIOCYC:HUMAN_PWY66-241] [PUBMED:15081921] [PUBMED:6406469] [PUBMED:22628] [PUBMED:11454731] [PUBMED:9378846] [PUBMED:6804243] [PUBMED:8830063] [PUBMED:10997944] [PUBMED:3931955] [PUBMED:12911050] [PUBMED:3107223]
melatonin degradation I [NCBI:545356] [BIOCYC:HUMAN_PWY-6398] [PUBMED:18344019] [PUBMED:18717775] [PUBMED:12899443] [PUBMED:17198536] [PUBMED:16219483] [PUBMED:9181522] [PUBMED:15981996] [PUBMED:12662344] [PUBMED:11485009] [PUBMED:18155917] [PUBMED:15616152] [PUBMED:16793870]
nicotine degradation III [NCBI:142438] [BIOCYC:HUMAN_PWY66-221] [PUBMED:11712903] [PUBMED:12433823] [PUBMED:10548320] [PUBMED:10224986] [PUBMED:3443673] [PUBMED:8123688] [PUBMED:12376133] [PUBMED:3391001] [PUBMED:7955812] [PUBMED:14166990] [PUBMED:2249376] [PUBMED:8646831] [PUBMED:10336551] [PUBMED:13932077] [PUBMED:8245272] [PUBMED:1352209] [PUBMED:10027795] [PUBMED:3557628] [PUBMED:14680362] [PUBMED:10482401] [PUBMED:8725403] [PUBMED:3806608] [PUBMED:10409404] [PUBMED:2362266] [PUBMED:2075752] [PUBMED:6705448] [PUBMED:8012160] [PUBMED:11050152] [PUBMED:14570768] [PUBMED:14004224] [PUBMED:8301571] [PUBMED:14257634] [PUBMED:8079500] [PUBMED:15734728] [PUBMED:13872096] [PUBMED:3054551] [PUBMED:43154] [PUBMED:9209247] [PUBMED:1643259]
nicotine degradation IV [NCBI:142437] [BIOCYC:HUMAN_PWY66-201] [PUBMED:8117928] [PUBMED:6705448] [PUBMED:423207] [PUBMED:1593921] [PUBMED:6896399] [PUBMED:2897456] [PUBMED:9512938] [PUBMED:8301571] [PUBMED:14570768] [PUBMED:3806608] [PUBMED:8725403] [PUBMED:15734728] [PUBMED:13872096] [PUBMED:14257634] [PUBMED:43154] [PUBMED:14004224] [PUBMED:3391001] [PUBMED:9209247] [PUBMED:1976062] [PUBMED:3054551] [PUBMED:4394772] [PUBMED:3557628] [PUBMED:10482401] [PUBMED:4144545] [PUBMED:10224986] [PUBMED:12376133] [PUBMED:12433823] [PUBMED:10548320] [PUBMED:11712903] [PUBMED:10336551] [PUBMED:8245272] [PUBMED:11050152] [PUBMED:10027795] [PUBMED:2249376] [PUBMED:8646831] [PUBMED:7955812] [PUBMED:1446003] [PUBMED:1352209] [PUBMED:13932077] [PUBMED:14166990]
superpathway of melatonin degradation [NCBI:545359] [BIOCYC:HUMAN_PWY-6402]
superpathway of tryptophan utilization [NCBI:835392] [BIOCYC:HUMAN_PWY66-401]