full name
paired like homeodomain 2
synonyms
ARP1, Brx1, IDG2, IGDS, IGDS2, IHG2, IRID2, Otlx2, PTX2, RGS, RIEG, RIEG1, RS, PITX2, ENSG00000164093
HGNC
HGNC:9005
Entrez Gene
Gene:5308
ENSEMBL
ENSG00000164093
location
chr: 4
start: 111538579
stop: 111563279
strand: -
OMIM
OMIM:601542:
PITX2
(Autosomal dominant inheritance)
OMIM:137600:
Anterior segment dysgenesis 4
OMIM:180500:
Axenfeld-Rieger syndrome, type 1
OMIM:180550:
Ring dermoid of cornea
transcripts
NM_001204399.1
NM_001204398.1
NM_153427.2
NM_153426.2
NM_001204397.1
NM_000325.5
pathways
Gene Expression
[NCBI:1269649]
[REACTOME:R-HSA-74160]
Generic Transcription Pathway
[NCBI:1269650]
[REACTOME:R-HSA-212436]
[PUBMED:15175151]
[PUBMED:14744435]
[PUBMED:15680972]
[PUBMED:11395415]
[PUBMED:15896744]
[PUBMED:10235266]
[PUBMED:14986688]
[PUBMED:12023297]
[PUBMED:15680973]
[PUBMED:16751179]
[PUBMED:11861166]
[PUBMED:16429119]
[PUBMED:16719718]
[PUBMED:16921404]
[PUBMED:15690163]
Regulation of Wnt-mediated beta catenin signaling and target gene transcription
[NCBI:169352]
[Pathway Interaction Database:wnt_beta_catenin_pathway]
[PUBMED:19901072]
[PUBMED:19699733]
[PUBMED:15142975]
[PUBMED:16565090]
[PUBMED:17372190]
[PUBMED:17310985]
[PUBMED:11751639]
[PUBMED:16301527]
[PUBMED:10921920]
[PUBMED:8622675]
[PUBMED:19571879]
[PUBMED:11445543]
[PUBMED:19066453]
[PUBMED:15768032]
[PUBMED:10704849]
[PUBMED:19940019]
[PUBMED:15378020]
[PUBMED:10318916]
[PUBMED:10617567]
[PUBMED:19435523]
[PUBMED:18511409]
[PUBMED:18006687]
[PUBMED:14638683]
[PUBMED:15782138]
[PUBMED:15143193]
[PUBMED:9671490]
[PUBMED:11263497]
[PUBMED:18193033]
[PUBMED:9751710]
[PUBMED:11532957]
[PUBMED:10898789]
[PUBMED:11266540]
[PUBMED:17090534]
[PUBMED:15492215]
[PUBMED:16309666]
[PUBMED:12502739]
[PUBMED:10980707]
[PUBMED:17945188]
[PUBMED:11572874]
[PUBMED:11809808]
[PUBMED:17113388]
[PUBMED:20128690]
[PUBMED:17709391]
[PUBMED:11500377]
[PUBMED:12464179]
[PUBMED:18347071]
[PUBMED:18347094]
[PUBMED:15592430]
[PUBMED:10958684]
[PUBMED:12408825]
[PUBMED:15525529]
[PUBMED:16581771]
[PUBMED:12052822]
[PUBMED:15668231]
[PUBMED:16014379]
[PUBMED:17923689]
[PUBMED:15592505]
[PUBMED:10984057]
[PUBMED:20044351]
[PUBMED:11940574]
[PUBMED:10747853]
[PUBMED:12606575]
[PUBMED:15728254]
[PUBMED:11080158]
[PUBMED:12446687]
[PUBMED:20128911]
[PUBMED:19816403]
[PUBMED:18573912]
[PUBMED:17397822]
[PUBMED:10489374]
[PUBMED:17052462]
[PUBMED:20371816]
[PUBMED:18347063]
[PUBMED:11035805]
[PUBMED:11792709]
[PUBMED:16899215]
[PUBMED:10882123]
[PUBMED:12200448]
[PUBMED:15060161]
[PUBMED:12711682]
[PUBMED:12582159]
[PUBMED:12646922]
[PUBMED:19460168]
[PUBMED:16778892]
[PUBMED:17306568]
[PUBMED:12712206]
[PUBMED:19711354]
[PUBMED:17893322]
[PUBMED:10934025]
[PUBMED:19503085]
[PUBMED:19433865]
TFAP2 (AP-2) family regulates transcription of other transcription factors
[NCBI:1427842]
[REACTOME:R-HSA-8866906]
[PUBMED:15475956]
[PUBMED:22735262]
TGF-beta signaling pathway
[NCBI:83064]
[KEGG:hsa04350]
[PUBMED:11836504]
[PUBMED:14534577]
[PUBMED:10021351]
[PUBMED:12809600]
[PUBMED:14557817]
[PUBMED:14769828]
[PUBMED:10519551]
[PUBMED:12163231]
[PUBMED:19758997]
[PUBMED:12466190]
[PUBMED:11252746]
[PUBMED:15063168]
[PUBMED:9847239]
[PUBMED:11252892]
Transcriptional regulation by the AP-2 (TFAP2) family of transcription factors
[NCBI:1427839]
[REACTOME:R-HSA-8864260]
[PUBMED:2010091]
[PUBMED:11744733]
[PUBMED:24469049]
[PUBMED:23382213]
[PUBMED:19798054]
[PUBMED:9162057]
[PUBMED:21084835]
[PUBMED:22735262]
[PUBMED:21375726]
[PUBMED:14744778]
[PUBMED:10648798]
[PUBMED:26832794]
[PUBMED:24835590]
[PUBMED:9687504]
[PUBMED:20805990]
[PUBMED:10497269]
[PUBMED:16420676]
[PUBMED:12072434]
[PUBMED:9850080]
[PUBMED:9182571]
[PUBMED:8988173]
[PUBMED:1998122]
[PUBMED:22371483]
[PUBMED:15870067]
[PUBMED:12586840]
[PUBMED:8895516]
[PUBMED:7891714]
[PUBMED:11694877]
[PUBMED:19115315]
[PUBMED:15475956]
[PUBMED:25114211]
