full name
ST3 beta-galactoside alpha-2,3-sialyltransferase 3

synonyms
EIEE15, MRT12, SIAT6, ST3GALII, ST3GalIII, ST3N, ST3GAL3, ENSG00000126091

HGNC
HGNC:10866

Entrez Gene
Gene:6487

ENSEMBL
ENSG00000126091

location
chr: 1
start: 44173204
stop: 44396837
strand: +

OMIM
OMIM:606494: ST3GAL3 (Autosomal recessive inheritance)
OMIM:615006: ?Epileptic encephalopathy, early infantile, 15
OMIM:611090: Mental retardation, autosomal recessive 12

transcripts
NM_174963.3
NM_174964.2
NM_174965.2
NM_001270465.1
NM_001270463.1
NM_174968.3
NR_073021.1
NR_073018.1
NR_073016.1
NM_006279.3
NM_001270459.1
NM_174966.2
NR_073023.1
NM_174967.2
NM_001270460.1
NM_174971.3
NM_174969.2
NM_001270461.1
NR_073020.1
NM_001270464.1
NM_174970.2
NM_001270466.1
NM_001270462.1
NR_073017.1
NR_073019.1

pathways
Asparagine N-linked glycosylation [NCBI:1268714] [REACTOME:R-HSA-446203] [PUBMED:19647993] [PUBMED:10580125] [PUBMED:16807922] [PUBMED:19616933] [PUBMED:20301507] [PUBMED:20301244]
Biosynthesis of the N-glycan precursor (dolichol lipid-linked oligosaccharide, LLO) and transfer to a nascent protein [NCBI:1268715] [REACTOME:R-HSA-446193] [PUBMED:20301507]
Glycosaminoglycan biosynthesis - keratan sulfate [NCBI:82983] [KEGG:hsa00533] [PUBMED:11030741] [PUBMED:12511560] [PUBMED:14706853]
Glycosaminoglycan metabolism [NCBI:1269972] [REACTOME:R-HSA-1630316] [PUBMED:18201392] [PUBMED:20301236] [PUBMED:820626]
Glycosphingolipid biosynthesis - lacto and neolacto series [NCBI:82995] [KEGG:hsa00601]
Keratan sulfate biosynthesis [NCBI:1269978] [REACTOME:R-HSA-2022854] [PUBMED:12512857] [PUBMED:11030741] [PUBMED:20213925]
Keratan sulfate/keratin metabolism [NCBI:1269977] [REACTOME:R-HSA-1638074] [PUBMED:11030741] [PUBMED:12512857] [PUBMED:16287098]
Metabolic pathways [NCBI:132956] [KEGG:hsa01100]
Metabolism [NCBI:1269956] [REACTOME:R-HSA-1430728]
Metabolism of carbohydrates [NCBI:1269957] [REACTOME:R-HSA-71387]
Metabolism of proteins [NCBI:1268677] [REACTOME:R-HSA-392499]
O-linked glycosylation [NCBI:1268734] [REACTOME:R-HSA-5173105] [PUBMED:22722607] [PUBMED:9673446]
O-linked glycosylation of mucins [NCBI:1268736] [REACTOME:R-HSA-913709] [PUBMED:20301232] [PUBMED:17988798]
Other types of O-glycan biosynthesis [NCBI:82978] [KEGG:hsa00514] [PUBMED:19429925] [PUBMED:22669261]
Post-translational protein modification [NCBI:1268701] [REACTOME:R-HSA-597592]
Pre-NOTCH Expression and Processing [NCBI:1269531] [REACTOME:R-HSA-1912422] [PUBMED:20805998] [PUBMED:21464368] [PUBMED:11707585] [PUBMED:9187150] [PUBMED:10669757] [PUBMED:9244302] [PUBMED:20080834] [PUBMED:18347015] [PUBMED:19773441] [PUBMED:18243100] [PUBMED:10935637] [PUBMED:11524432] [PUBMED:9207795] [PUBMED:12486116] [PUBMED:20495621] [PUBMED:10935626] [PUBMED:20351093] [PUBMED:19723635] [PUBMED:19701457] [PUBMED:21551231] [PUBMED:21602795] [PUBMED:9653148] [PUBMED:21490058] [PUBMED:19714243] [PUBMED:9727485]
Pre-NOTCH Processing in Golgi [NCBI:1269534] [REACTOME:R-HSA-1912420] [PUBMED:9244302] [PUBMED:1764995] [PUBMED:8681805] [PUBMED:7918097] [PUBMED:10935637] [PUBMED:10366590] [PUBMED:10935626] [PUBMED:20170518] [PUBMED:9727485] [PUBMED:8293978] [PUBMED:19701457] [PUBMED:20197277] [PUBMED:9653148] [PUBMED:10669757] [PUBMED:9187150] [PUBMED:10459009] [PUBMED:1295745] [PUBMED:11135303] [PUBMED:11707585]
Sialic acid metabolism [NCBI:1268721] [REACTOME:R-HSA-4085001] [PUBMED:21689720] [PUBMED:22526796]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:19648010] [PUBMED:17604717] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:15863030] [PUBMED:21252999] [PUBMED:19379690] [PUBMED:19536106] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:15450248] [PUBMED:15520807] [PUBMED:16939974] [PUBMED:18483217] [PUBMED:18043707] [PUBMED:19762341] [PUBMED:21781017] [PUBMED:17084981] [PUBMED:19619488] [PUBMED:17496910]
Signaling by NOTCH [NCBI:1269530] [REACTOME:R-HSA-157118]
Synthesis of substrates in N-glycan biosythesis [NCBI:1268716] [REACTOME:R-HSA-446219] [PUBMED:18597486]
Termination of O-glycan biosynthesis [NCBI:1268737] [REACTOME:R-HSA-977068] [PUBMED:20301246]
terminal O-glycans residues modification [NCBI:1108788] [BIOCYC:HUMAN_PWY-7434] [PUBMED:13767181] [PUBMED:2502398] [PUBMED:3014508] [PUBMED:4971635] [PUBMED:2419911] [PUBMED:3121604] [PUBMED:3134348] [PUBMED:13292836] [PUBMED:2503516] [PUBMED:9435216] [PUBMED:10580128] [PUBMED:6490658] [PUBMED:9405390] [PUBMED:2738063] [PUBMED:9792633] [PUBMED:2104828] [PUBMED:10473568] [PUBMED:2464598]