Logo
full name
mastermind like transcriptional coactivator 3

synonyms
CAGH3, ERDA3, GDN, MAM-2, MAM2, TNRC3, MAML3, ENSG00000196782

HGNC
HGNC:16272

Entrez Gene
Gene:55534

ENSEMBL
ENSG00000196782

location
chr: 4
start: 140637545
stop: 141075233
strand: -

transcripts
ENST00000509479.2

pathways
Constitutive Signaling by NOTCH1 HD+PEST Domain Mutants [NCBI:1268891] [REACTOME:R-HSA-2894862] [PUBMED:15472075] [PUBMED:17646408] [PUBMED:17646409] [PUBMED:16738328]
Constitutive Signaling by NOTCH1 PEST Domain Mutants [NCBI:1268889] [REACTOME:R-HSA-2644606] [PUBMED:15472075] [PUBMED:17646408] [PUBMED:17646409]
Disease [NCBI:1268854] [REACTOME:R-HSA-1643685]
Diseases of signal transduction [NCBI:1268855] [REACTOME:R-HSA-5663202] [PUBMED:12509752]
Gene Expression [NCBI:1269649] [REACTOME:R-HSA-74160]
Generic Transcription Pathway [NCBI:1269650] [REACTOME:R-HSA-212436] [PUBMED:15175151] [PUBMED:14744435] [PUBMED:15680972] [PUBMED:11395415] [PUBMED:15896744] [PUBMED:10235266] [PUBMED:14986688] [PUBMED:12023297] [PUBMED:15680973] [PUBMED:16751179] [PUBMED:11861166] [PUBMED:16429119] [PUBMED:16719718] [PUBMED:16921404] [PUBMED:15690163]
NOTCH1 Intracellular Domain Regulates Transcription [NCBI:1269537] [REACTOME:R-HSA-2122947] [PUBMED:11044625] [PUBMED:8649374] [PUBMED:21737748] [PUBMED:9694793] [PUBMED:20972443] [PUBMED:11585921] [PUBMED:17114293] [PUBMED:8001118] [PUBMED:18094723] [PUBMED:8687460] [PUBMED:16256737] [PUBMED:16530044] [PUBMED:12050117] [PUBMED:10964718] [PUBMED:12391150] [PUBMED:7566092] [PUBMED:15546612] [PUBMED:15107403] [PUBMED:18374649] [PUBMED:14980219] [PUBMED:11461910] [PUBMED:10713164]
NOTCH2 intracellular domain regulates transcription [NCBI:1269540] [REACTOME:R-HSA-2197563] [PUBMED:23362348] [PUBMED:18724371] [PUBMED:11986231] [PUBMED:23362349] [PUBMED:11866432] [PUBMED:21898486] [PUBMED:11101851]
Notch signaling pathway [NCBI:83062] [KEGG:hsa04330] [NCBI:169345] [Pathway Interaction Database:notch_pathway] [PUBMED:11459941] [PUBMED:12682059] [PUBMED:11825871] [PUBMED:17658278] [PUBMED:15998794] [PUBMED:11101851] [PUBMED:19686683] [PUBMED:18490439] [PUBMED:11150244] [PUBMED:9694793] [PUBMED:10206645] [PUBMED:19704010] [PUBMED:16137758] [PUBMED:15288258] [PUBMED:17392792] [PUBMED:8749394] [PUBMED:15965470] [PUBMED:14566063] [PUBMED:19567869] [PUBMED:11585921] [PUBMED:18676613] [PUBMED:12913000] [PUBMED:10593990] [PUBMED:15274632] [PUBMED:11777909] [PUBMED:12015972] [PUBMED:10028969] [PUBMED:18043734] [PUBMED:17658279] [PUBMED:17575125] [PUBMED:10958687] [PUBMED:15300010] [PUBMED:10882062] [PUBMED:12374742] [PUBMED:11782429] [PUBMED:9653148] [PUBMED:9315665] [PUBMED:8643690] [PUBMED:17114293] [PUBMED:10837024] [PUBMED:15067010] [PUBMED:17296795] [PUBMED:10940313] [PUBMED:18628966] [PUBMED:12826675] [PUBMED:12681948] [PUBMED:16492672] [PUBMED:12551931] [PUBMED:15082708] [PUBMED:12464310] [PUBMED:12794186] [PUBMED:16107360] [PUBMED:19726682] [PUBMED:11486031] [PUBMED:16287852] [PUBMED:12297508] [PUBMED:16061358] [PUBMED:17107962] [PUBMED:9244302] [PUBMED:11425854] [PUBMED:9620803] [PUBMED:15272268] [PUBMED:18417156] [PUBMED:16000382] [PUBMED:11896183] [PUBMED:11604511] [PUBMED:16847353] [PUBMED:11432830] [PUBMED:15652348] [PUBMED:12417415] [PUBMED:14567914] [PUBMED:11006133] [PUBMED:18077452] [PUBMED:16144902] [PUBMED:15288257] [PUBMED:15585829] [PUBMED:12370315] [PUBMED:15288260] [PUBMED:17434929] [PUBMED:12814948] [PUBMED:10882063] [PUBMED:11518718]
Notch-HLH transcription pathway [NCBI:1269651] [REACTOME:R-HSA-350054] [PUBMED:16429119] [PUBMED:12897056] [PUBMED:17157496] [PUBMED:12050117] [PUBMED:11535832] [PUBMED:12374742] [PUBMED:16921404] [PUBMED:11112321] [PUBMED:11604511] [PUBMED:10487760] [PUBMED:16024779] [PUBMED:15546612] [PUBMED:14986688] [PUBMED:12370315] [PUBMED:10713164] [PUBMED:16530045]
Pre-NOTCH Expression and Processing [NCBI:1269531] [REACTOME:R-HSA-1912422] [PUBMED:21490058] [PUBMED:20805998] [PUBMED:21464368] [PUBMED:9187150] [PUBMED:11707585] [PUBMED:10669757] [PUBMED:9244302] [PUBMED:20080834] [PUBMED:18347015] [PUBMED:19773441] [PUBMED:9207795] [PUBMED:10935637] [PUBMED:19714243] [PUBMED:18243100] [PUBMED:19723635] [PUBMED:11524432] [PUBMED:9727485] [PUBMED:12486116] [PUBMED:20495621] [PUBMED:10935626] [PUBMED:20351093] [PUBMED:19701457] [PUBMED:21602795] [PUBMED:21551231] [PUBMED:9653148]
Pre-NOTCH Transcription and Translation [NCBI:1269532] [REACTOME:R-HSA-1912408] [PUBMED:9693032] [PUBMED:19773441] [PUBMED:20080834] [PUBMED:20351093] [PUBMED:10545110] [PUBMED:20495621] [PUBMED:19714243] [PUBMED:17823410] [PUBMED:19723635] [PUBMED:17554337] [PUBMED:21602795] [PUBMED:21551231] [PUBMED:1425352] [PUBMED:16773578] [PUBMED:17540598] [PUBMED:7698746] [PUBMED:20805998] [PUBMED:11187898] [PUBMED:1831692] [PUBMED:1764995] [PUBMED:8878478] [PUBMED:17540599]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by NOTCH [NCBI:1269530] [REACTOME:R-HSA-157118]
Signaling by NOTCH1 [NCBI:1269535] [REACTOME:R-HSA-1980143] [PUBMED:20972443] [PUBMED:8649374] [PUBMED:11740940] [PUBMED:15965470] [PUBMED:16284625] [PUBMED:9694793] [PUBMED:19567869] [PUBMED:12354787] [PUBMED:11585921] [PUBMED:20418862] [PUBMED:11226752] [PUBMED:9590294] [PUBMED:9315665] [PUBMED:17114293] [PUBMED:18094723] [PUBMED:10964718] [PUBMED:10879540] [PUBMED:8001118] [PUBMED:12050117] [PUBMED:18043734] [PUBMED:9819428] [PUBMED:15824097] [PUBMED:9244301] [PUBMED:16256737] [PUBMED:8687460] [PUBMED:19726682] [PUBMED:8313469] [PUBMED:15574878] [PUBMED:18296446] [PUBMED:16530044] [PUBMED:9620803] [PUBMED:18237417] [PUBMED:7566092] [PUBMED:18628966] [PUBMED:12391150] [PUBMED:12530964] [PUBMED:11006133] [PUBMED:18374649] [PUBMED:15107403] [PUBMED:18077452] [PUBMED:15652348] [PUBMED:15546612] [PUBMED:10882063] [PUBMED:14980219] [PUBMED:10713164] [PUBMED:9462510] [PUBMED:11461910] [PUBMED:14567914] [PUBMED:17003037] [PUBMED:17028573] [PUBMED:11044625] [PUBMED:10206645] [PUBMED:19524514]
Signaling by NOTCH1 HD+PEST Domain Mutants in Cancer [NCBI:1268890] [REACTOME:R-HSA-2894858] [PUBMED:15472075]
Signaling by NOTCH1 PEST Domain Mutants in Cancer [NCBI:1268888] [REACTOME:R-HSA-2644602] [PUBMED:17646408] [PUBMED:15472075] [PUBMED:17646409]
Signaling by NOTCH1 in Cancer [NCBI:1268883] [REACTOME:R-HSA-2644603] [PUBMED:17646409] [PUBMED:10367900] [PUBMED:16738328] [PUBMED:15951812] [PUBMED:22399357] [PUBMED:15546612] [PUBMED:11461910] [PUBMED:9118226] [PUBMED:15951813] [PUBMED:17646408] [PUBMED:15472075] [PUBMED:11585921] [PUBMED:17909001] [PUBMED:16612405] [PUBMED:1831692] [PUBMED:15187027]
Signaling by NOTCH2 [NCBI:1269538] [REACTOME:R-HSA-1980145] [PUBMED:20156974] [PUBMED:18724371] [PUBMED:21378989] [PUBMED:11187898] [PUBMED:10958687] [PUBMED:9207788] [PUBMED:803282] [PUBMED:18469519] [PUBMED:20816392] [PUBMED:19379690] [PUBMED:11518718] [PUBMED:14567914] [PUBMED:11986231] [PUBMED:10934472] [PUBMED:11101851] [PUBMED:11866432] [PUBMED:21378985] [PUBMED:10206645] [PUBMED:20816393] [PUBMED:10551863] [PUBMED:9207787] [PUBMED:15569487] [PUBMED:21632553] [PUBMED:21681853] [PUBMED:16773578]
Th1 and Th2 cell differentiation [NCBI:1458885] [KEGG:hsa04658] [PUBMED:15819694] [PUBMED:12171942] [PUBMED:19165228] [PUBMED:23336087] [PUBMED:26044597] [PUBMED:19151746] [PUBMED:19362457] [PUBMED:22044277] [PUBMED:11752608] [PUBMED:23405903] [PUBMED:19375293] [PUBMED:24113868] [PUBMED:19151747] [PUBMED:23624818] [PUBMED:22566933] [PUBMED:11121747] [PUBMED:20969597] [PUBMED:20065998]