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Genes
ANAPC10
Gene - ANAPC10
full name
anaphase promoting complex subunit 10
synonyms
APC10, DOC1, ANAPC10, ENSG00000164162
HGNC
HGNC:24077
Entrez Gene
Gene:10393
ENSEMBL
ENSG00000164162
location
chr: 4
start: 145915727
stop: 146019693
strand: -
transcripts
NM_001256708.1
NM_001256712.1
NM_014885.4
NR_046345.1
NM_001256706.1
NM_001256710.1
NM_001256707.1
NM_001256711.1
NM_001256709.1
pathways
APC-Cdc20 mediated degradation of Nek2A
[NCBI:1269847]
[REACTOME:R-HSA-179409]
[PUBMED:11742988]
[PUBMED:16648845]
APC/C-mediated degradation of cell cycle proteins
[NCBI:1269838]
[REACTOME:R-HSA-174143]
[PUBMED:15678131]
[PUBMED:12049731]
APC/C:Cdc20 mediated degradation of Cyclin B
[NCBI:1269848]
[REACTOME:R-HSA-174048]
[PUBMED:11285280]
APC/C:Cdc20 mediated degradation of Securin
[NCBI:1269849]
[REACTOME:R-HSA-174154]
[PUBMED:12070128]
[PUBMED:10827941]
APC/C:Cdc20 mediated degradation of mitotic proteins
[NCBI:1269844]
[REACTOME:R-HSA-176409]
[PUBMED:15949434]
[PUBMED:10465783]
APC/C:Cdh1 mediated degradation of Cdc20 and other APC/C:Cdh1 targeted proteins in late mitosis/early G1
[NCBI:1269851]
[REACTOME:R-HSA-174178]
[PUBMED:16413484]
[PUBMED:15678131]
APC:Cdc20 mediated degradation of cell cycle proteins prior to satisfation of the cell cycle checkpoint
[NCBI:1269845]
[REACTOME:R-HSA-179419]
Activation of APC/C and APC/C:Cdc20 mediated degradation of mitotic proteins
[NCBI:1269842]
[REACTOME:R-HSA-176814]
[PUBMED:15678131]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Antigen processing: Ubiquitination & Proteasome degradation
[NCBI:1269193]
[REACTOME:R-HSA-983168]
[PUBMED:12648452]
[PUBMED:11917093]
[PUBMED:19489725]
[PUBMED:14734113]
[PUBMED:20351195]
[PUBMED:17145306]
Autodegradation of Cdh1 by Cdh1:APC/C
[NCBI:1269852]
[REACTOME:R-HSA-174084]
[PUBMED:15029244]
Cdc20:Phospho-APC/C mediated degradation of Cyclin A
[NCBI:1269846]
[REACTOME:R-HSA-174184]
[PUBMED:11285280]
Cell Cycle
[NCBI:1269741]
[REACTOME:R-HSA-1640170]
Cell Cycle Checkpoints
[NCBI:1269742]
[REACTOME:R-HSA-69620]
Cell Cycle, Mitotic
[NCBI:1269763]
[REACTOME:R-HSA-69278]
Cell cycle
[NCBI:83054]
[KEGG:hsa04110]
[PUBMED:7973727]
[PUBMED:17568790]
[PUBMED:9832503]
[PUBMED:16936746]
[PUBMED:9029154]
[PUBMED:12573239]
[PUBMED:19020303]
[PUBMED:9618481]
[PUBMED:12809600]
[PUBMED:8242749]
[PUBMED:10385618]
[PUBMED:17426725]
[PUBMED:17018296]
[PUBMED:16212951]
[PUBMED:12925736]
[PUBMED:11099028]
[PUBMED:15568976]
[PUBMED:15838516]
[PUBMED:15838523]
[PUBMED:15876871]
[PUBMED:7908906]
[PUBMED:9889196]
Cellular Senescence
[NCBI:1270426]
[REACTOME:R-HSA-2559583]
[PUBMED:21078816]
[PUBMED:18711403]
[PUBMED:22048312]
[PUBMED:19818705]
[PUBMED:17662938]
[PUBMED:23746838]
[PUBMED:9282108]
[PUBMED:17667954]
[PUBMED:13905658]
Cellular responses to stress
[NCBI:1270414]
[REACTOME:R-HSA-2262752]
[PUBMED:15709958]
Class I MHC mediated antigen processing & presentation
[NCBI:1269192]
[REACTOME:R-HSA-983169]
[PUBMED:8717519]
[PUBMED:17145306]
[PUBMED:18926908]
[PUBMED:17055423]
[PUBMED:12495737]
[PUBMED:18641646]
[PUBMED:18243674]
Conversion from APC/C:Cdc20 to APC/C:Cdh1 in late anaphase
[NCBI:1269850]
[REACTOME:R-HSA-176407]
[PUBMED:15678131]
HTLV-I infection
[NCBI:373901]
[KEGG:hsa05166]
[PUBMED:17446673]
[PUBMED:16436385]
[PUBMED:14686485]
[PUBMED:19861996]
[PUBMED:19092975]
[PUBMED:11325603]
[PUBMED:16155602]
[PUBMED:12910251]
[PUBMED:16155605]
[PUBMED:16036567]
[PUBMED:11244044]
[PUBMED:18702816]
[PUBMED:15569630]
[PUBMED:21114861]
[PUBMED:16155611]
[PUBMED:17384582]
[PUBMED:16155608]
[PUBMED:10602469]
[PUBMED:19014483]
[PUBMED:9325311]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inactivation of APC/C via direct inhibition of the APC/C complex
[NCBI:1269762]
[REACTOME:R-HSA-141430]
[PUBMED:14593737]
[PUBMED:11535616]
[PUBMED:9637688]
Inhibition of the proteolytic activity of APC/C required for the onset of anaphase by mitotic spindle checkpoint components
[NCBI:1269761]
[REACTOME:R-HSA-141405]
[PUBMED:14593737]
M Phase
[NCBI:1269810]
[REACTOME:R-HSA-68886]
Mitotic Anaphase
[NCBI:1269825]
[REACTOME:R-HSA-68882]
Mitotic Metaphase and Anaphase
[NCBI:1269823]
[REACTOME:R-HSA-2555396]
Mitotic Spindle Checkpoint
[NCBI:1269758]
[REACTOME:R-HSA-69618]
[PUBMED:14593737]
[PUBMED:12360190]
Oocyte meiosis
[NCBI:126909]
[KEGG:hsa04114]
[PUBMED:16760654]
[PUBMED:17480229]
[PUBMED:15136768]
[PUBMED:18946022]
[PUBMED:18598214]
[PUBMED:16518630]
[PUBMED:18631137]
[PUBMED:15182704]
[PUBMED:15182701]
[PUBMED:16554437]
[PUBMED:14691134]
[PUBMED:18550795]
[PUBMED:18096427]
[PUBMED:14517314]
[PUBMED:18311174]
Phosphorylation of the APC/C
[NCBI:1269843]
[REACTOME:R-HSA-176412]
[PUBMED:10793135]
Progesterone-mediated oocyte maturation
[NCBI:119304]
[KEGG:hsa04914]
[PUBMED:10497333]
[PUBMED:12084906]
[PUBMED:12045215]
[PUBMED:11063930]
[PUBMED:12477927]
[PUBMED:11148128]
[PUBMED:11730319]
[PUBMED:12374568]
Regulation of APC/C activators between G1/S and early anaphase
[NCBI:1269839]
[REACTOME:R-HSA-176408]
[PUBMED:16508672]
[PUBMED:12049731]
[PUBMED:12208841]
[PUBMED:15678131]
Regulation of mitotic cell cycle
[NCBI:1269837]
[REACTOME:R-HSA-453276]
Senescence-Associated Secretory Phenotype (SASP)
[NCBI:1270431]
[REACTOME:R-HSA-2559582]
[PUBMED:18411265]
[PUBMED:21979375]
[PUBMED:18267069]
[PUBMED:19597488]
[PUBMED:19218920]
[PUBMED:20818427]
[PUBMED:11114305]
[PUBMED:8617720]
[PUBMED:22178396]
[PUBMED:19805069]
[PUBMED:23770676]
[PUBMED:8384717]
[PUBMED:18555777]
[PUBMED:21686281]
[PUBMED:20351173]
[PUBMED:8688489]
[PUBMED:19053174]
[PUBMED:8234276]
[PUBMED:18555778]
Separation of Sister Chromatids
[NCBI:1269826]
[REACTOME:R-HSA-2467813]
[PUBMED:11081627]
[PUBMED:10411507]
[PUBMED:12070128]
[PUBMED:12194817]
[PUBMED:11509732]
Ubiquitin mediated proteolysis
[NCBI:83056]
[KEGG:hsa04120]
[PUBMED:16405856]
[PUBMED:12944364]
[PUBMED:16922408]
[PUBMED:17588513]
[PUBMED:16922367]
[PUBMED:16922370]
[PUBMED:16816840]