Home
About
Citations
Statistics
Download
Login
Home
Genes
TLR2
Gene - TLR2
full name
toll like receptor 2
synonyms
CD282, TIL4, TLR2, ENSG00000137462
HGNC
HGNC:11848
Entrez Gene
Gene:7097
ENSEMBL
ENSG00000137462
location
chr: 4
start: 154605404
stop: 154627243
strand: +
OMIM
OMIM:603028
: TLR2
OMIM:114500
: {Colorectal cancer, susceptibility to}
OMIM:246300
: {Leprosy, susceptibility to}
OMIM:607948
: {Mycobacterium tuberculosis, susceptibility to}
transcripts
NM_003264.3
pathways
Activated TLR4 signalling
[NCBI:1269236]
[REACTOME:R-HSA-166054]
[PUBMED:15276183]
[PUBMED:15588429]
[PUBMED:15845500]
[PUBMED:15596121]
Adaptive Immune System
[NCBI:1269171]
[REACTOME:R-HSA-1280218]
[PUBMED:16551257]
[PUBMED:21682741]
[PUBMED:11861602]
Amoebiasis
[NCBI:167324]
[KEGG:hsa05146]
[PUBMED:9832261]
[PUBMED:16380324]
[PUBMED:14700586]
[PUBMED:18725798]
[PUBMED:12142490]
[PUBMED:10637584]
[PUBMED:20145703]
[PUBMED:11378035]
[PUBMED:12160867]
[PUBMED:15813717]
[PUBMED:19207103]
[PUBMED:12660071]
[PUBMED:20303955]
[PUBMED:11352795]
[PUBMED:14502002]
[PUBMED:10756002]
[PUBMED:17702556]
[PUBMED:17576362]
Antigen processing-Cross presentation
[NCBI:1269195]
[REACTOME:R-HSA-1236975]
[PUBMED:17157489]
[PUBMED:20171863]
[PUBMED:16181333]
[PUBMED:15761154]
[PUBMED:16181335]
[PUBMED:19218463]
Antimicrobial peptides
[NCBI:1457777]
[REACTOME:R-HSA-6803157]
[PUBMED:12615953]
[PUBMED:24287494]
Beta defensins
[NCBI:1269267]
[REACTOME:R-HSA-1461957]
[PUBMED:16710608]
Chagas disease (American trypanosomiasis)
[NCBI:147809]
[KEGG:hsa05142]
[PUBMED:12377585]
[PUBMED:9794425]
[PUBMED:1717552]
[PUBMED:16238097]
[PUBMED:10066513]
[PUBMED:12874238]
[PUBMED:12036740]
[PUBMED:15917295]
[PUBMED:12055254]
[PUBMED:17651955]
[PUBMED:1396957]
[PUBMED:16175174]
[PUBMED:2194668]
[PUBMED:9190942]
[PUBMED:12377942]
[PUBMED:12427093]
[PUBMED:10234174]
[PUBMED:16030288]
[PUBMED:15223603]
[PUBMED:17110955]
Class I MHC mediated antigen processing & presentation
[NCBI:1269192]
[REACTOME:R-HSA-983169]
[PUBMED:8717519]
[PUBMED:17145306]
[PUBMED:18926908]
[PUBMED:17055423]
[PUBMED:12495737]
[PUBMED:18641646]
[PUBMED:18243674]
Defensins
[NCBI:1269265]
[REACTOME:R-HSA-1461973]
[PUBMED:15372083]
Disease
[NCBI:1268854]
[REACTOME:R-HSA-1643685]
Diseases associated with the TLR signaling cascade
[NCBI:1269157]
[REACTOME:R-HSA-5602358]
[PUBMED:23622315]
[PUBMED:21734245]
[PUBMED:22610250]
[PUBMED:16176658]
Diseases of Immune System
[NCBI:1269156]
[REACTOME:R-HSA-5260271]
[PUBMED:24795713]
[PUBMED:22165913]
ER-Phagosome pathway
[NCBI:1269197]
[REACTOME:R-HSA-1236974]
[PUBMED:16213220]
[PUBMED:20171863]
[PUBMED:14508490]
[PUBMED:17027300]
[PUBMED:14561893]
[PUBMED:15845646]
[PUBMED:22915823]
[PUBMED:18006660]
[PUBMED:14508489]
[PUBMED:12151002]
[PUBMED:15728715]
Hepatitis B
[NCBI:694606]
[KEGG:hsa05161]
[PUBMED:19854353]
[PUBMED:11604508]
[PUBMED:11325602]
[PUBMED:18931690]
[PUBMED:16891440]
[PUBMED:17158882]
[PUBMED:11099494]
[PUBMED:9325306]
[PUBMED:18024894]
[PUBMED:11483993]
[PUBMED:15107488]
[PUBMED:11278872]
[PUBMED:21647825]
[PUBMED:11287574]
[PUBMED:18481805]
[PUBMED:17188775]
[PUBMED:19784739]
[PUBMED:19263472]
[PUBMED:16203685]
[PUBMED:18605975]
[PUBMED:10454581]
[PUBMED:22504921]
[PUBMED:21334391]
[PUBMED:20657822]
[PUBMED:18046710]
[PUBMED:9843511]
[PUBMED:15542625]
[PUBMED:21618535]
[PUBMED:15132991]
[PUBMED:15173177]
[PUBMED:12771941]
[PUBMED:21994545]
[PUBMED:8764004]
[PUBMED:16459163]
[PUBMED:9738022]
[PUBMED:11821950]
[PUBMED:12839924]
Herpes simplex infection
[NCBI:377873]
[KEGG:hsa05168]
[PUBMED:12224518]
[PUBMED:17913820]
[PUBMED:12844494]
[PUBMED:10998601]
[PUBMED:15163721]
[PUBMED:19694546]
[PUBMED:16297150]
[PUBMED:14747533]
[PUBMED:12826401]
[PUBMED:14963113]
[PUBMED:15056211]
[PUBMED:12797447]
[PUBMED:21107701]
[PUBMED:10918307]
[PUBMED:10696424]
[PUBMED:16076403]
[PUBMED:10364308]
[PUBMED:17222692]
[PUBMED:9621021]
[PUBMED:12224508]
[PUBMED:19879619]
[PUBMED:11070032]
[PUBMED:9499021]
[PUBMED:18596690]
[PUBMED:12525427]
[PUBMED:12224517]
[PUBMED:10196275]
[PUBMED:15047834]
[PUBMED:18508584]
[PUBMED:20036979]
IRAK4 deficiency (TLR2/4)
[NCBI:1269158]
[REACTOME:R-HSA-5603041]
[PUBMED:18669862]
[PUBMED:12637671]
[PUBMED:24316379]
[PUBMED:15069402]
Immune System
[NCBI:1269170]
[REACTOME:R-HSA-168256]
Inflammatory bowel disease (IBD)
[NCBI:842771]
[KEGG:hsa05321]
[PUBMED:17499605]
[PUBMED:12006974]
[PUBMED:18053739]
[PUBMED:20134493]
[PUBMED:10898785]
[PUBMED:18563156]
[PUBMED:23176791]
[PUBMED:18200661]
[PUBMED:12797537]
[PUBMED:21487504]
[PUBMED:19381306]
[PUBMED:21681604]
[PUBMED:19322214]
[PUBMED:16493424]
[PUBMED:18242222]
[PUBMED:12042806]
[PUBMED:9759857]
Innate Immune System
[NCBI:1269203]
[REACTOME:R-HSA-168249]
Legionellosis
[NCBI:469200]
[KEGG:hsa05134]
[PUBMED:19021631]
[PUBMED:19157961]
[PUBMED:20375353]
[PUBMED:19478083]
[PUBMED:18284575]
[PUBMED:19386084]
[PUBMED:19666608]
[PUBMED:15972519]
[PUBMED:18549456]
[PUBMED:1721820]
[PUBMED:17124169]
[PUBMED:19687203]
[PUBMED:18363881]
[PUBMED:19343209]
[PUBMED:20941588]
[PUBMED:16824952]
[PUBMED:18281405]
[PUBMED:18048909]
[PUBMED:16495539]
[PUBMED:12427954]
Leishmaniasis
[NCBI:144181]
[KEGG:hsa05140]
[PUBMED:11890722]
[PUBMED:7916951]
[PUBMED:10417174]
[PUBMED:11298294]
[PUBMED:10586030]
[PUBMED:15322192]
[PUBMED:15831826]
[PUBMED:11728310]
[PUBMED:15039466]
[PUBMED:10462516]
[PUBMED:10608501]
[PUBMED:15721837]
[PUBMED:15639739]
[PUBMED:14762510]
[PUBMED:18793215]
[PUBMED:7591091]
[PUBMED:12438359]
[PUBMED:18070909]
[PUBMED:17543969]
[PUBMED:15983048]
[PUBMED:16848789]
[PUBMED:10770277]
[PUBMED:9504340]
Malaria
[NCBI:152665]
[KEGG:hsa05144]
[PUBMED:15106591]
[PUBMED:11224682]
[PUBMED:17630968]
[PUBMED:18250459]
[PUBMED:16138104]
[PUBMED:20091081]
[PUBMED:8920859]
[PUBMED:19101208]
[PUBMED:16019257]
[PUBMED:15464448]
[PUBMED:11832955]
[PUBMED:12364790]
[PUBMED:10885986]
[PUBMED:15094163]
[PUBMED:14737184]
[PUBMED:15463497]
[PUBMED:16468982]
[PUBMED:19967139]
Measles
[NCBI:213306]
[KEGG:hsa05162]
[PUBMED:16237742]
[PUBMED:12804771]
[PUBMED:19198562]
[PUBMED:20376484]
[PUBMED:11385511]
[PUBMED:16963735]
[PUBMED:19198566]
[PUBMED:18922877]
[PUBMED:19203114]
[PUBMED:12620806]
[PUBMED:16690907]
[PUBMED:17720800]
[PUBMED:20636817]
[PUBMED:12410527]
[PUBMED:11582511]
[PUBMED:19203109]
[PUBMED:19203113]
[PUBMED:14585342]
[PUBMED:12805463]
MyD88 deficiency (TLR2/4)
[NCBI:1269160]
[REACTOME:R-HSA-5602498]
[PUBMED:18669862]
[PUBMED:24316379]
[PUBMED:15069402]
MyD88:Mal cascade initiated on plasma membrane
[NCBI:1269237]
[REACTOME:R-HSA-166058]
[PUBMED:15276183]
Neutrophil degranulation
[NCBI:1457780]
[REACTOME:R-HSA-6798695]
[PUBMED:20338884]
[PUBMED:1378856]
[PUBMED:17627888]
[PUBMED:23650620]
[PUBMED:8692836]
PI3K-Akt signaling pathway
[NCBI:692234]
[KEGG:hsa04151]
[PUBMED:12048182]
[PUBMED:11357143]
[PUBMED:21440011]
[PUBMED:15209374]
[PUBMED:12669022]
[PUBMED:18842113]
[PUBMED:16847462]
[PUBMED:12660731]
[PUBMED:17360849]
[PUBMED:9838078]
[PUBMED:15505410]
[PUBMED:16248975]
[PUBMED:12531180]
[PUBMED:21779440]
[PUBMED:16187290]
[PUBMED:15784165]
[PUBMED:21620960]
Phagosome
[NCBI:153910]
[KEGG:hsa04145]
[PUBMED:17637737]
[PUBMED:18513324]
[PUBMED:15894272]
[PUBMED:10684585]
[PUBMED:18492791]
[PUBMED:15036145]
[PUBMED:17245426]
Proteoglycans in cancer
[NCBI:782000]
[KEGG:hsa05205]
[PUBMED:19433454]
[PUBMED:20655987]
[PUBMED:18798267]
[PUBMED:10633082]
[PUBMED:10687947]
[PUBMED:22735579]
[PUBMED:24412155]
[PUBMED:9346940]
[PUBMED:22087031]
[PUBMED:22194599]
[PUBMED:14711376]
[PUBMED:19255147]
[PUBMED:15655247]
[PUBMED:11717317]
[PUBMED:17971838]
[PUBMED:18413366]
[PUBMED:20974860]
[PUBMED:11830493]
[PUBMED:23058688]
[PUBMED:18450475]
[PUBMED:12748184]
[PUBMED:19733083]
[PUBMED:18812315]
[PUBMED:12509413]
[PUBMED:21155971]
[PUBMED:11931647]
[PUBMED:18949819]
[PUBMED:12729888]
[PUBMED:15994311]
[PUBMED:23305321]
[PUBMED:18505598]
[PUBMED:22563565]
[PUBMED:22033227]
Regulation of TLR by endogenous ligand
[NCBI:1427857]
[REACTOME:R-HSA-5686938]
[PUBMED:25391648]
[PUBMED:20706656]
[PUBMED:20629986]
[PUBMED:20179153]
Rheumatoid arthritis
[NCBI:200309]
[KEGG:hsa05323]
[PUBMED:9627005]
[PUBMED:17195034]
[PUBMED:15059264]
[PUBMED:17380158]
[PUBMED:20651747]
[PUBMED:19455385]
[PUBMED:20305562]
[PUBMED:20510236]
[PUBMED:19184540]
[PUBMED:20392226]
[PUBMED:17502360]
[PUBMED:16313349]
[PUBMED:16127012]
[PUBMED:15055519]
[PUBMED:20036936]
[PUBMED:11861618]
[PUBMED:19585227]
[PUBMED:20193003]
Toll Like Receptor 2 (TLR2) Cascade
[NCBI:1269238]
[REACTOME:R-HSA-181438]
[PUBMED:10820283]
Toll Like Receptor 4 (TLR4) Cascade
[NCBI:1269234]
[REACTOME:R-HSA-166016]
Toll Like Receptor TLR1:TLR2 Cascade
[NCBI:1269239]
[REACTOME:R-HSA-168179]
[PUBMED:12975352]
Toll Like Receptor TLR6:TLR2 Cascade
[NCBI:1269240]
[REACTOME:R-HSA-168188]
[PUBMED:14977973]
Toll-Like Receptors Cascades
[NCBI:1269204]
[REACTOME:R-HSA-168898]
[PUBMED:15950447]
[PUBMED:12893815]
[PUBMED:15976490]
[PUBMED:15585605]
[PUBMED:14751757]
Toll-like receptor signaling pathway
[NCBI:83076]
[KEGG:hsa04620]
[PUBMED:16924467]
[PUBMED:17395581]
[PUBMED:17637696]
[PUBMED:12734364]
[PUBMED:17507094]
[PUBMED:14698224]
[PUBMED:11101877]
[PUBMED:16497588]
[PUBMED:14751764]
[PUBMED:17275323]
[PUBMED:17457343]
[PUBMED:16932750]
Toxoplasmosis
[NCBI:169642]
[KEGG:hsa05145]
[PUBMED:18617274]
[PUBMED:19400868]
[PUBMED:17024357]
[PUBMED:19744886]
[PUBMED:19891610]
[PUBMED:17110955]
[PUBMED:12106793]
[PUBMED:12580944]
[PUBMED:12857995]
[PUBMED:10234174]
[PUBMED:18327664]
[PUBMED:10525166]
[PUBMED:18059289]
[PUBMED:18775432]
[PUBMED:14642303]
[PUBMED:15361242]
[PUBMED:16339966]
[PUBMED:14987366]
[PUBMED:15639739]
Tuberculosis
[NCBI:213780]
[KEGG:hsa05152]
[PUBMED:20199890]
[PUBMED:21274449]
[PUBMED:17359235]
[PUBMED:20415982]
[PUBMED:18541216]
[PUBMED:19369951]
[PUBMED:15083155]
[PUBMED:11378475]
[PUBMED:15228522]
[PUBMED:19634703]
[PUBMED:21274433]
[PUBMED:19563525]
[PUBMED:18407066]
[PUBMED:18288961]
[PUBMED:16200082]
[PUBMED:17785780]
[PUBMED:11932234]