Logo
full name
caspase 3

synonyms
CPP32, CPP32B, SCA-1, CASP3, ENSG00000164305

HGNC
HGNC:1504

Entrez Gene
Gene:836

ENSEMBL
ENSG00000164305

location
chr: 4
start: 185548850
stop: 185570629
strand: -

transcripts
NM_032991.2
NM_004346.3

pathways
AGE-RAGE signaling pathway in diabetic complications [NCBI:1319988] [KEGG:hsa04933] [PUBMED:23776698] [PUBMED:15569303] [PUBMED:16894049] [PUBMED:18323529] [PUBMED:11375353] [PUBMED:21111800] [PUBMED:19404313] [PUBMED:20470857] [PUBMED:17005604] [PUBMED:23961320] [PUBMED:21261520] [PUBMED:11180401] [PUBMED:18922799] [PUBMED:21680901] [PUBMED:11684565] [PUBMED:21590515] [PUBMED:12709399] [PUBMED:20300563] [PUBMED:21440603] [PUBMED:22558488]
Activation of DNA fragmentation factor [NCBI:1270293] [REACTOME:R-HSA-211227] [PUBMED:9422506] [PUBMED:12748178] [PUBMED:10318789] [PUBMED:10713148] [PUBMED:15723341]
Activation of caspases through apoptosome-mediated cleavage [NCBI:1270283] [REACTOME:R-HSA-111459] [PUBMED:9922454] [PUBMED:9390557]
Alzheimer's disease [NCBI:83097] [KEGG:hsa05010] [PUBMED:18782350] [PUBMED:18035450] [PUBMED:15177383] [PUBMED:10527810] [PUBMED:15363492] [PUBMED:16677790] [PUBMED:15295589] [PUBMED:17055782] [PUBMED:15864339] [PUBMED:15750290] [PUBMED:18675468] [PUBMED:15232608] [PUBMED:9848086] [PUBMED:11484003] [PUBMED:10830966] [PUBMED:16529745] [PUBMED:17568632]
Amoebiasis [NCBI:167324] [KEGG:hsa05146] [PUBMED:9832261] [PUBMED:16380324] [PUBMED:14700586] [PUBMED:18725798] [PUBMED:12142490] [PUBMED:10637584] [PUBMED:20145703] [PUBMED:11378035] [PUBMED:12160867] [PUBMED:15813717] [PUBMED:19207103] [PUBMED:12660071] [PUBMED:20303955] [PUBMED:11352795] [PUBMED:14502002] [PUBMED:10756002] [PUBMED:17702556] [PUBMED:17576362]
Amyotrophic lateral sclerosis (ALS) [NCBI:83099] [KEGG:hsa05014] [PUBMED:16026864] [PUBMED:16924260] [PUBMED:11513882] [PUBMED:17015226] [PUBMED:16723044] [PUBMED:10970056] [PUBMED:16909020] [PUBMED:12531867] [PUBMED:16713195] [PUBMED:16603792] [PUBMED:11870681] [PUBMED:16050975] [PUBMED:17409386] [PUBMED:11239414] [PUBMED:18519638] [PUBMED:14569202] [PUBMED:12728264] [PUBMED:11715057] [PUBMED:17566607] [PUBMED:17434459] [PUBMED:16909017] [PUBMED:12595144] [PUBMED:15310460] [PUBMED:14739060]
Apoptosis [NCBI:83060] [KEGG:hsa04210] [NCBI:1270262] [REACTOME:R-HSA-109581] [PUBMED:12189384] [PUBMED:20533903] [PUBMED:18208375] [PUBMED:22429822] [PUBMED:15218528] [PUBMED:24769728] [PUBMED:18023214] [PUBMED:25526085] [PUBMED:23070002] [PUBMED:15654015] [PUBMED:15601572] [PUBMED:14561771] [PUBMED:24278747] [PUBMED:21914490] [PUBMED:22465226] [PUBMED:21145844] [PUBMED:12838338] [PUBMED:18238895] [PUBMED:12949498] [PUBMED:18304445] [PUBMED:14737178] [PUBMED:26231733] [PUBMED:9916983] [PUBMED:14634621] [PUBMED:19770840] [PUBMED:22075987] [PUBMED:4561027] [PUBMED:20075940] [PUBMED:9894605] [PUBMED:26615431] [PUBMED:12505355] [PUBMED:11520933] [PUBMED:19148180] [PUBMED:16397578] [PUBMED:15719025] [PUBMED:15322527] [PUBMED:15725726] [PUBMED:12209154] [PUBMED:23803157]
Apoptosis - multiple species [NCBI:1384747] [KEGG:hsa04215] [PUBMED:23457257] [PUBMED:11858838] [PUBMED:15963254] [PUBMED:20041301] [PUBMED:24393571] [PUBMED:21150934] [PUBMED:15107838] [PUBMED:10578171] [PUBMED:15082313] [PUBMED:19659442] [PUBMED:20479784] [PUBMED:22689371] [PUBMED:20978240] [PUBMED:25862972] [PUBMED:20028968] [PUBMED:25991373]
Apoptosis induced DNA fragmentation [NCBI:1270292] [REACTOME:R-HSA-140342] [PUBMED:15723341]
Apoptotic cleavage of cell adhesion proteins [NCBI:1270290] [REACTOME:R-HSA-351906] [PUBMED:11500511] [PUBMED:16286477] [PUBMED:17559062]
Apoptotic cleavage of cellular proteins [NCBI:1270288] [REACTOME:R-HSA-111465] [PUBMED:17254298] [PUBMED:17599937] [PUBMED:12655297]
Apoptotic execution phase [NCBI:1270287] [REACTOME:R-HSA-75153] [PUBMED:12655297]
Apoptotic factor-mediated response [NCBI:1270280] [REACTOME:R-HSA-111471] [PUBMED:12042762] [PUBMED:15077149]
Calcineurin-regulated NFAT-dependent transcription in lymphocytes [NCBI:137993] [Pathway Interaction Database:nfat_tfpathway] [PUBMED:11254715] [PUBMED:11356833] [PUBMED:12121669] [PUBMED:10878360] [PUBMED:11786533] [PUBMED:8284217] [PUBMED:10816557] [PUBMED:11956291] [PUBMED:7510691] [PUBMED:9195954] [PUBMED:8240350] [PUBMED:12452838] [PUBMED:8623163] [PUBMED:15834410] [PUBMED:10894164] [PUBMED:10970869] [PUBMED:10755616] [PUBMED:14607827] [PUBMED:12705856] [PUBMED:12086671] [PUBMED:7982959] [PUBMED:9047239] [PUBMED:12374808] [PUBMED:14573767] [PUBMED:12560487] [PUBMED:10570264] [PUBMED:8397339] [PUBMED:12055628] [PUBMED:15308098] [PUBMED:12065418] [PUBMED:7891702] [PUBMED:7749982] [PUBMED:14973438] [PUBMED:8674125] [PUBMED:16873067] [PUBMED:12453415] [PUBMED:8441422] [PUBMED:1737937] [PUBMED:10671476] [PUBMED:8376940] [PUBMED:9545284]
Caspase activation via extrinsic apoptotic signalling pathway [NCBI:1270263] [REACTOME:R-HSA-5357769] [PUBMED:11048727]
Caspase cascade in apoptosis [NCBI:137974] [Pathway Interaction Database:caspase_pathway] [PUBMED:7774019] [PUBMED:8626669] [PUBMED:9850096] [PUBMED:11803376] [PUBMED:15189451] [PUBMED:10564664] [PUBMED:9642276] [PUBMED:10567584] [PUBMED:12419244] [PUBMED:11423904] [PUBMED:9422506] [PUBMED:11438643] [PUBMED:9070648] [PUBMED:9588194] [PUBMED:11085743] [PUBMED:9298992] [PUBMED:9933635] [PUBMED:9528810] [PUBMED:9323209] [PUBMED:10809769] [PUBMED:8700869] [PUBMED:9463409] [PUBMED:10497198] [PUBMED:11953316] [PUBMED:9422513] [PUBMED:10409650] [PUBMED:11463840] [PUBMED:10611247] [PUBMED:8605870]
Caspase-mediated cleavage of cytoskeletal proteins [NCBI:1270289] [REACTOME:R-HSA-264870] [PUBMED:17254298] [PUBMED:12655297] [PUBMED:17599937]
Cell death signalling via NRAGE, NRIF and NADE [NCBI:1269447] [REACTOME:R-HSA-204998] [PUBMED:12787561]
Colorectal cancer [NCBI:83106] [KEGG:hsa05210] [PUBMED:15479695] [PUBMED:11459867] [PUBMED:9196022] [PUBMED:11170304] [PUBMED:12951588] [PUBMED:15349822] [PUBMED:15711891] [PUBMED:16042571] [PUBMED:15000146] [PUBMED:12737309] [PUBMED:10505543] [PUBMED:11078609] [PUBMED:11223406] [PUBMED:16326109] [PUBMED:16699851] [PUBMED:11477132] [PUBMED:12621137] [PUBMED:15573119] [PUBMED:16555243] [PUBMED:15310786]
Cytochrome c-mediated apoptotic response [NCBI:1270281] [REACTOME:R-HSA-111461] [PUBMED:15184073]
Cytokine Signaling in Immune system [NCBI:1269310] [REACTOME:R-HSA-1280215] [PUBMED:12613569]
Degradation of the extracellular matrix [NCBI:1270257] [REACTOME:R-HSA-1474228] [PUBMED:21917992]
Epithelial cell signaling in Helicobacter pylori infection [NCBI:83102] [KEGG:hsa05120] [PUBMED:11389469] [PUBMED:15694859] [PUBMED:14700549] [PUBMED:12197905]
Extracellular matrix organization [NCBI:1270244] [REACTOME:R-HSA-1474244] [PUBMED:21123617] [PUBMED:21917992] [PUBMED:12845610]
FAS (CD95) signaling pathway [NCBI:138081] [Pathway Interaction Database:faspathway] [PUBMED:9765224] [PUBMED:11717445] [PUBMED:9727491] [PUBMED:11279218] [PUBMED:12110583] [PUBMED:11739735] [PUBMED:8521815] [PUBMED:9184224] [PUBMED:20153221] [PUBMED:9126929] [PUBMED:10200443] [PUBMED:16033886] [PUBMED:8681377] [PUBMED:9880544] [PUBMED:9501089] [PUBMED:10535980] [PUBMED:9727492] [PUBMED:7523573] [PUBMED:11101870] [PUBMED:9321399] [PUBMED:9362518] [PUBMED:12724420] [PUBMED:16498403] [PUBMED:11583996] [PUBMED:15557123] [PUBMED:7536343] [PUBMED:12832037] [PUBMED:9576928] [PUBMED:9228058] [PUBMED:7538908] [PUBMED:18635548] [PUBMED:20038679] [PUBMED:10894163] [PUBMED:12545171] [PUBMED:16619028] [PUBMED:9351817] [PUBMED:9045686] [PUBMED:15289496]
HIV-1 Nef: Negative effector of Fas and TNF-alpha [NCBI:137995] [Pathway Interaction Database:hivnefpathway] [PUBMED:9740801] [PUBMED:10224289] [PUBMED:10940292] [PUBMED:9915703] [PUBMED:9564042] [PUBMED:9743501] [PUBMED:9873064] [PUBMED:12748303] [PUBMED:9867840] [PUBMED:11298454] [PUBMED:9184224] [PUBMED:9294162] [PUBMED:9727492] [PUBMED:9244310] [PUBMED:10318789] [PUBMED:12887920] [PUBMED:9230442] [PUBMED:9020361] [PUBMED:9108473] [PUBMED:9215629] [PUBMED:9384571]
Hepatitis B [NCBI:694606] [KEGG:hsa05161] [PUBMED:19854353] [PUBMED:11604508] [PUBMED:11325602] [PUBMED:18931690] [PUBMED:16891440] [PUBMED:17158882] [PUBMED:11099494] [PUBMED:9325306] [PUBMED:18024894] [PUBMED:11483993] [PUBMED:15107488] [PUBMED:11278872] [PUBMED:21647825] [PUBMED:11287574] [PUBMED:18481805] [PUBMED:17188775] [PUBMED:19784739] [PUBMED:19263472] [PUBMED:16203685] [PUBMED:18605975] [PUBMED:10454581] [PUBMED:22504921] [PUBMED:21334391] [PUBMED:20657822] [PUBMED:18046710] [PUBMED:9843511] [PUBMED:15542625] [PUBMED:21618535] [PUBMED:15132991] [PUBMED:15173177] [PUBMED:12771941] [PUBMED:21994545] [PUBMED:8764004] [PUBMED:16459163] [PUBMED:9738022] [PUBMED:11821950] [PUBMED:12839924]
Herpes simplex infection [NCBI:377873] [KEGG:hsa05168] [PUBMED:12224518] [PUBMED:17913820] [PUBMED:12844494] [PUBMED:10998601] [PUBMED:15163721] [PUBMED:19694546] [PUBMED:16297150] [PUBMED:14747533] [PUBMED:12826401] [PUBMED:14963113] [PUBMED:15056211] [PUBMED:12797447] [PUBMED:21107701] [PUBMED:10918307] [PUBMED:10696424] [PUBMED:16076403] [PUBMED:10364308] [PUBMED:17222692] [PUBMED:9621021] [PUBMED:12224508] [PUBMED:19879619] [PUBMED:11070032] [PUBMED:9499021] [PUBMED:18596690] [PUBMED:12525427] [PUBMED:12224517] [PUBMED:10196275] [PUBMED:15047834] [PUBMED:18508584] [PUBMED:20036979]
Huntington's disease [NCBI:83100] [KEGG:hsa05016] [PUBMED:15336977] [PUBMED:11738471] [PUBMED:11807533] [PUBMED:15996546] [PUBMED:14526190] [PUBMED:15242639] [PUBMED:17041811] [PUBMED:15996541] [PUBMED:18951640] [PUBMED:15459747] [PUBMED:16288298] [PUBMED:17081970] [PUBMED:15695335] [PUBMED:12372277] [PUBMED:11839795]
IL-17 signaling pathway [NCBI:1474301] [KEGG:hsa04657] [PUBMED:17921324] [PUBMED:24011563] [PUBMED:21349428] [PUBMED:20383173] [PUBMED:20514051] [PUBMED:20177959] [PUBMED:18178098] [PUBMED:21074482] [PUBMED:21130872] [PUBMED:17027518] [PUBMED:23917206] [PUBMED:23116200] [PUBMED:18701318] [PUBMED:26252407] [PUBMED:22851696] [PUBMED:21155836] [PUBMED:25145755] [PUBMED:17177681] [PUBMED:19575028] [PUBMED:23557798] [PUBMED:21852080] [PUBMED:22324470]
Immune System [NCBI:1269170] [REACTOME:R-HSA-168256]
Intrinsic Pathway for Apoptosis [NCBI:1270268] [REACTOME:R-HSA-109606] [PUBMED:12042762] [PUBMED:11711427] [PUBMED:15077149]
LPA receptor mediated events [NCBI:137928] [Pathway Interaction Database:lysophospholipid_pathway] [PUBMED:10601262] [PUBMED:16289596] [PUBMED:7809106] [PUBMED:10342794] [PUBMED:15928312] [PUBMED:16769764] [PUBMED:11243883] [PUBMED:14688263] [PUBMED:10551845] [PUBMED:16687414] [PUBMED:9819398] [PUBMED:7527052] [PUBMED:9600933] [PUBMED:2551506] [PUBMED:15988003] [PUBMED:10644509] [PUBMED:16199135] [PUBMED:15728708] [PUBMED:1637305] [PUBMED:7476905] [PUBMED:7510708] [PUBMED:8647803] [PUBMED:10420989] [PUBMED:12880866] [PUBMED:10766839] [PUBMED:12181443] [PUBMED:15461590] [PUBMED:16452634] [PUBMED:16197369] [PUBMED:10779388] [PUBMED:10506190] [PUBMED:9305878] [PUBMED:16904289] [PUBMED:15878967] [PUBMED:15143197] [PUBMED:11948806] [PUBMED:11040035] [PUBMED:12393875] [PUBMED:9407095] [PUBMED:15280372] [PUBMED:16890224] [PUBMED:8805276]
Legionellosis [NCBI:469200] [KEGG:hsa05134] [PUBMED:19021631] [PUBMED:19157961] [PUBMED:20375353] [PUBMED:19478083] [PUBMED:18284575] [PUBMED:19386084] [PUBMED:19666608] [PUBMED:15972519] [PUBMED:18549456] [PUBMED:1721820] [PUBMED:17124169] [PUBMED:19687203] [PUBMED:18363881] [PUBMED:19343209] [PUBMED:20941588] [PUBMED:16824952] [PUBMED:18281405] [PUBMED:18048909] [PUBMED:16495539] [PUBMED:12427954]
Ligand-independent caspase activation via DCC [NCBI:1270267] [REACTOME:R-HSA-418889] [PUBMED:10348349] [PUBMED:15310786] [PUBMED:12598906] [PUBMED:12011067]
MAPK signaling pathway [NCBI:83048] [KEGG:hsa04010] [PUBMED:11749383] [PUBMED:12566928] [PUBMED:12849693] [PUBMED:12676795] [PUBMED:12947395] [PUBMED:14597384] [PUBMED:11369511] [PUBMED:12191611] [PUBMED:12390245]
MicroRNAs in cancer [NCBI:852705] [KEGG:hsa05206] [PUBMED:23075324] [PUBMED:21742789] [PUBMED:22351564] [PUBMED:18817506] [PUBMED:22345301] [PUBMED:21402473] [PUBMED:22926415] [PUBMED:23165235] [PUBMED:19630570] [PUBMED:21565290] [PUBMED:23091478] [PUBMED:23462054] [PUBMED:23316212] [PUBMED:19773200] [PUBMED:22035854] [PUBMED:20221895] [PUBMED:20345848] [PUBMED:22580099] [PUBMED:20128019]
NADE modulates death signalling [NCBI:1269450] [REACTOME:R-HSA-205025] [PUBMED:11278287]
Natural killer cell mediated cytotoxicity [NCBI:83079] [KEGG:hsa04650] [PUBMED:12530970] [PUBMED:15567854] [PUBMED:8942070] [PUBMED:11905813] [PUBMED:9143705] [PUBMED:9862693] [PUBMED:11895890] [PUBMED:12205470] [PUBMED:11836514] [PUBMED:15607806] [PUBMED:16002670] [PUBMED:15618404] [PUBMED:11390470] [PUBMED:11062493] [PUBMED:14710949] [PUBMED:12752668] [PUBMED:15607802] [PUBMED:16109839] [PUBMED:12766758] [PUBMED:16177799]
Non-alcoholic fatty liver disease (NAFLD) [NCBI:862188] [KEGG:hsa04932] [PUBMED:21038418] [PUBMED:17498512] [PUBMED:19352614] [PUBMED:23299992] [PUBMED:22570745] [PUBMED:9285483] [PUBMED:12891546] [PUBMED:18061659] [PUBMED:22705006] [PUBMED:16364488] [PUBMED:18242193] [PUBMED:16374858] [PUBMED:22940046] [PUBMED:20619513] [PUBMED:20303879] [PUBMED:14685853] [PUBMED:16406828] [PUBMED:23545492] [PUBMED:21145844]
Parkinson's disease [NCBI:83098] [KEGG:hsa05012] [PUBMED:15767499] [PUBMED:12461550] [PUBMED:21811441] [PUBMED:17911161] [PUBMED:15525720] [PUBMED:16022590] [PUBMED:12971891] [PUBMED:15681812] [PUBMED:16495942] [PUBMED:11331916] [PUBMED:18426756] [PUBMED:16278972] [PUBMED:18680555] [PUBMED:12938733] [PUBMED:15770999] [PUBMED:12728264] [PUBMED:15054086] [PUBMED:20236221] [PUBMED:22927178]
Pathways in cancer [NCBI:83105] [KEGG:hsa05200] [PUBMED:12244301] [PUBMED:15156182] [PUBMED:16899407] [PUBMED:12621137] [PUBMED:21193867] [PUBMED:16001072] [PUBMED:11707511] [PUBMED:11253051] [PUBMED:11071626] [PUBMED:17251915] [PUBMED:11736900] [PUBMED:16557281] [PUBMED:16699851] [PUBMED:16189702] [PUBMED:11902573] [PUBMED:16555243] [PUBMED:8069858] [PUBMED:15310786] [PUBMED:9834202] [PUBMED:16700615] [PUBMED:12545153] [PUBMED:15656799] [PUBMED:12154354] [PUBMED:11895903] [PUBMED:11527574] [PUBMED:16326109] [PUBMED:16339096] [PUBMED:11160144] [PUBMED:15724144] [PUBMED:12951584] [PUBMED:10647931] [PUBMED:16881963] [PUBMED:15557758] [PUBMED:11477132] [PUBMED:15721476] [PUBMED:15625120] [PUBMED:16236521] [PUBMED:14967450] [PUBMED:15942304] [PUBMED:17287871] [PUBMED:14634372] [PUBMED:15573119] [PUBMED:15009714] [PUBMED:16112428] [PUBMED:15611513] [PUBMED:16001050] [PUBMED:15349822] [PUBMED:16551846] [PUBMED:15978322] [PUBMED:15774796] [PUBMED:16352814] [PUBMED:12951588] [PUBMED:10944551] [PUBMED:10740269] [PUBMED:15639402] [PUBMED:12407699] [PUBMED:11130178] [PUBMED:15109562] [PUBMED:11170304] [PUBMED:11276000] [PUBMED:9643506] [PUBMED:16248975] [PUBMED:16242838] [PUBMED:12946833] [PUBMED:11559746] [PUBMED:9196022] [PUBMED:12079267] [PUBMED:15468170] [PUBMED:16064138] [PUBMED:14580692] [PUBMED:15082523] [PUBMED:15551095] [PUBMED:17062879] [PUBMED:17211469] [PUBMED:11720739] [PUBMED:12588368] [PUBMED:11057895] [PUBMED:9422516] [PUBMED:12894244] [PUBMED:15479695] [PUBMED:16189154] [PUBMED:12878745] [PUBMED:11900250] [PUBMED:11103787] [PUBMED:15122209] [PUBMED:12711111] [PUBMED:12243753] [PUBMED:16306523] [PUBMED:16702400] [PUBMED:15270885] [PUBMED:14685170] [PUBMED:14586404] [PUBMED:11078609] [PUBMED:15284264] [PUBMED:10505543] [PUBMED:11223406] [PUBMED:14982876] [PUBMED:12648469] [PUBMED:12867060] [PUBMED:15711891] [PUBMED:12094241] [PUBMED:16642045] [PUBMED:11463388] [PUBMED:12762887] [PUBMED:15746962] [PUBMED:15823750] [PUBMED:16750612] [PUBMED:16484590] [PUBMED:11459867] [PUBMED:16146838] [PUBMED:14556242] [PUBMED:15947972] [PUBMED:12563308] [PUBMED:16946003] [PUBMED:15948971] [PUBMED:11407945] [PUBMED:12737309] [PUBMED:16095998] [PUBMED:12351585] [PUBMED:24508914] [PUBMED:12084351] [PUBMED:11807782] [PUBMED:14695152] [PUBMED:10453277] [PUBMED:17554387] [PUBMED:15841168] [PUBMED:12616528] [PUBMED:10403855] [PUBMED:16054233] [PUBMED:16474624] [PUBMED:16822996] [PUBMED:17028294] [PUBMED:11224709] [PUBMED:11750244] [PUBMED:11905738] [PUBMED:15719031] [PUBMED:10843728] [PUBMED:16110317] [PUBMED:11721960] [PUBMED:12741677] [PUBMED:7585656] [PUBMED:12801837] [PUBMED:16551847] [PUBMED:12459728] [PUBMED:11431710] [PUBMED:12468433] [PUBMED:11165748] [PUBMED:16042571] [PUBMED:16508724] [PUBMED:15000146] [PUBMED:17149381] [PUBMED:15948711] [PUBMED:14747944] [PUBMED:14737121] [PUBMED:12379883] [PUBMED:17158541] [PUBMED:12850530] [PUBMED:10835690] [PUBMED:16870043]
Pertussis [NCBI:218111] [KEGG:hsa05133] [PUBMED:20610650] [PUBMED:12701623] [PUBMED:15201703] [PUBMED:18401006] [PUBMED:20210554] [PUBMED:16622221] [PUBMED:17148436] [PUBMED:21204863] [PUBMED:20404851] [PUBMED:10540218] [PUBMED:16999837] [PUBMED:16481212] [PUBMED:16863919] [PUBMED:16390441] [PUBMED:21423776] [PUBMED:17328678] [PUBMED:12915094]
Platinum drug resistance [NCBI:1404797] [KEGG:hsa01524] [PUBMED:24074238] [PUBMED:26867799] [PUBMED:14609433] [PUBMED:26184483] [PUBMED:24874729] [PUBMED:15607932] [PUBMED:25546083] [PUBMED:25058905] [PUBMED:19190080] [PUBMED:14576837] [PUBMED:20811617] [PUBMED:21892204] [PUBMED:20647037] [PUBMED:17336087] [PUBMED:26886018] [PUBMED:23442359] [PUBMED:17625587]
Programmed Cell Death [NCBI:1270261] [REACTOME:R-HSA-5357801] [PUBMED:25236395]
Proteoglycans in cancer [NCBI:782000] [KEGG:hsa05205] [PUBMED:19433454] [PUBMED:20655987] [PUBMED:18798267] [PUBMED:10633082] [PUBMED:10687947] [PUBMED:22735579] [PUBMED:24412155] [PUBMED:9346940] [PUBMED:22087031] [PUBMED:22194599] [PUBMED:14711376] [PUBMED:19255147] [PUBMED:15655247] [PUBMED:11717317] [PUBMED:17971838] [PUBMED:18413366] [PUBMED:20974860] [PUBMED:11830493] [PUBMED:23058688] [PUBMED:18450475] [PUBMED:12748184] [PUBMED:19733083] [PUBMED:18812315] [PUBMED:12509413] [PUBMED:21155971] [PUBMED:11931647] [PUBMED:18949819] [PUBMED:12729888] [PUBMED:15994311] [PUBMED:23305321] [PUBMED:18505598] [PUBMED:22563565] [PUBMED:22033227]
Role of Calcineurin-dependent NFAT signaling in lymphocytes [NCBI:137953] [Pathway Interaction Database:nfat_3pathway] [PUBMED:15743762] [PUBMED:9109491] [PUBMED:1715244] [PUBMED:15121840] [PUBMED:10195903] [PUBMED:10788511] [PUBMED:9630228] [PUBMED:9834092] [PUBMED:9655484] [PUBMED:10933397] [PUBMED:11030334] [PUBMED:8684469] [PUBMED:10861295] [PUBMED:15117942] [PUBMED:12351631] [PUBMED:15902271] [PUBMED:16406492] [PUBMED:10944115] [PUBMED:10611249] [PUBMED:15733859] [PUBMED:15757646] [PUBMED:9768749] [PUBMED:9072970] [PUBMED:12510191] [PUBMED:9585406] [PUBMED:293720] [PUBMED:12925851] [PUBMED:16943420] [PUBMED:11823475] [PUBMED:16141075] [PUBMED:9374467] [PUBMED:9660798] [PUBMED:7528941] [PUBMED:11356833] [PUBMED:10593895] [PUBMED:10866678] [PUBMED:9171236] [PUBMED:12809556] [PUBMED:10652349] [PUBMED:12021260] [PUBMED:16455648]
SMAC binds to IAPs [NCBI:1270285] [REACTOME:R-HSA-111463] [PUBMED:12042762]
SMAC-mediated apoptotic response [NCBI:1270284] [REACTOME:R-HSA-111469] [PUBMED:15077149]
SMAC-mediated dissociation of IAP:caspase complexes [NCBI:1270286] [REACTOME:R-HSA-111464] [PUBMED:12042762]
Serotonergic synapse [NCBI:525336] [KEGG:hsa04726] [PUBMED:9658404] [PUBMED:15034221] [PUBMED:11043573] [PUBMED:9651340] [PUBMED:9542727] [PUBMED:18676031] [PUBMED:12543273] [PUBMED:15710402] [PUBMED:16826372] [PUBMED:19545642] [PUBMED:11916537] [PUBMED:11701344] [PUBMED:12676358] [PUBMED:20561690] [PUBMED:16896947]
Signal Transduction [NCBI:1269379] [REACTOME:R-HSA-162582] [PUBMED:17604717] [PUBMED:19648010] [PUBMED:16260143] [PUBMED:11742412] [PUBMED:19536106] [PUBMED:15863030] [PUBMED:19379690] [PUBMED:19458711] [PUBMED:19935667] [PUBMED:21252999] [PUBMED:15520807] [PUBMED:17496910] [PUBMED:15450248] [PUBMED:18043707] [PUBMED:16939974] [PUBMED:19762341] [PUBMED:18483217] [PUBMED:17084981] [PUBMED:21781017] [PUBMED:19619488]
Signaling by Hippo [NCBI:1269616] [REACTOME:R-HSA-2028269] [PUBMED:20850437] [PUBMED:20951342] [PUBMED:20598891] [PUBMED:20439427] [PUBMED:11278283] [PUBMED:20452772] [PUBMED:21224387] [PUBMED:20412773] [PUBMED:21233212] [PUBMED:20868367]
Signaling by Interleukins [NCBI:1269318] [REACTOME:R-HSA-449147] [PUBMED:19302047] [PUBMED:12445398]
Signalling by NGF [NCBI:1269443] [REACTOME:R-HSA-166520]
Stimulation of the cell death response by PAK-2p34 [NCBI:1270294] [REACTOME:R-HSA-211736] [PUBMED:15471851] [PUBMED:9786869] [PUBMED:12853446] [PUBMED:15234964]
Syndecan-2-mediated signaling events [NCBI:138031] [Pathway Interaction Database:syndecan_2_pathway] [PUBMED:17623663] [PUBMED:11373281] [PUBMED:16357320] [PUBMED:12507425] [PUBMED:16945929] [PUBMED:14976204] [PUBMED:10772816] [PUBMED:10843988] [PUBMED:8528141] [PUBMED:15936998] [PUBMED:10734053] [PUBMED:11179419] [PUBMED:9660868] [PUBMED:16198615] [PUBMED:9660869] [PUBMED:15752734] [PUBMED:10446183] [PUBMED:11580899] [PUBMED:17548511] [PUBMED:11931647] [PUBMED:16139226] [PUBMED:16008343] [PUBMED:14527339] [PUBMED:16997272] [PUBMED:10639336] [PUBMED:16440330] [PUBMED:11018053] [PUBMED:10704377] [PUBMED:9244383] [PUBMED:12860416]
TNF signaling pathway [NCBI:812256] [KEGG:hsa04668] [PUBMED:20489699] [PUBMED:14532286] [PUBMED:21232019] [PUBMED:11897488] [PUBMED:22296764] [PUBMED:10581243] [PUBMED:23085193] [PUBMED:23531747]
Toxoplasmosis [NCBI:169642] [KEGG:hsa05145] [PUBMED:18617274] [PUBMED:19400868] [PUBMED:17024357] [PUBMED:19744886] [PUBMED:19891610] [PUBMED:17110955] [PUBMED:12106793] [PUBMED:12580944] [PUBMED:12857995] [PUBMED:10234174] [PUBMED:18327664] [PUBMED:10525166] [PUBMED:18059289] [PUBMED:18775432] [PUBMED:14642303] [PUBMED:15361242] [PUBMED:16339966] [PUBMED:14987366] [PUBMED:15639739]
Tuberculosis [NCBI:213780] [KEGG:hsa05152] [PUBMED:20199890] [PUBMED:21274449] [PUBMED:17359235] [PUBMED:20415982] [PUBMED:18541216] [PUBMED:19369951] [PUBMED:15083155] [PUBMED:11378475] [PUBMED:15228522] [PUBMED:19634703] [PUBMED:21274433] [PUBMED:19563525] [PUBMED:18407066] [PUBMED:18288961] [PUBMED:16200082] [PUBMED:17785780] [PUBMED:11932234]
Viral carcinogenesis [NCBI:658418] [KEGG:hsa05203] [PUBMED:9990017] [PUBMED:15173177] [PUBMED:16036567] [PUBMED:16581947] [PUBMED:9060639] [PUBMED:17457345] [PUBMED:15956361] [PUBMED:21421561] [PUBMED:18391203] [PUBMED:21040832] [PUBMED:9837909] [PUBMED:17645777] [PUBMED:15967719] [PUBMED:12686421] [PUBMED:17049016] [PUBMED:21152115] [PUBMED:11160754] [PUBMED:21966251] [PUBMED:17979705] [PUBMED:8617242] [PUBMED:12925958] [PUBMED:10873631] [PUBMED:21250384] [PUBMED:15614436] [PUBMED:10354594] [PUBMED:20494113] [PUBMED:18702816] [PUBMED:9651361] [PUBMED:16459163] [PUBMED:11278402] [PUBMED:15510157] [PUBMED:19956178] [PUBMED:18251977] [PUBMED:11766888] [PUBMED:10824878] [PUBMED:21372216] [PUBMED:11244044] [PUBMED:17894800] [PUBMED:11905817] [PUBMED:21347341] [PUBMED:12186904] [PUBMED:9374493] [PUBMED:16352731] [PUBMED:12770701] [PUBMED:17384582] [PUBMED:14506283] [PUBMED:11091847] [PUBMED:17267064] [PUBMED:11886269] [PUBMED:21177815] [PUBMED:10400746] [PUBMED:19156753] [PUBMED:9882379] [PUBMED:14559998] [PUBMED:15767449] [PUBMED:22110506] [PUBMED:20534855] [PUBMED:15542638] [PUBMED:9343405] [PUBMED:10405893] [PUBMED:19400863] [PUBMED:9349482] [PUBMED:14747563] [PUBMED:21647825] [PUBMED:12970441] [PUBMED:11669605] [PUBMED:15795286] [PUBMED:21994562] [PUBMED:14530271] [PUBMED:9594662] [PUBMED:22566809] [PUBMED:19651473] [PUBMED:8756622] [PUBMED:15105524] [PUBMED:15452270] [PUBMED:18948197] [PUBMED:16760382] [PUBMED:10793105] [PUBMED:21084867] [PUBMED:16308315] [PUBMED:16155604] [PUBMED:16381817] [PUBMED:16828973] [PUBMED:15342967] [PUBMED:15692053] [PUBMED:10855768] [PUBMED:19078975] [PUBMED:12379483] [PUBMED:15310405] [PUBMED:8223437] [PUBMED:16939421] [PUBMED:12910250] [PUBMED:16039586] [PUBMED:18201576] [PUBMED:21102637] [PUBMED:21743832] [PUBMED:20592731] [PUBMED:10644344] [PUBMED:10074132] [PUBMED:19715458] [PUBMED:16155601] [PUBMED:11604508] [PUBMED:15919895] [PUBMED:11099494] [PUBMED:18385245] [PUBMED:19854353] [PUBMED:12101418]
Viral myocarditis [NCBI:125138] [KEGG:hsa05416] [PUBMED:19357408] [PUBMED:18545064] [PUBMED:18357777] [PUBMED:11524405] [PUBMED:12920582] [PUBMED:14522402] [PUBMED:17200452] [PUBMED:18039131] [PUBMED:16413486] [PUBMED:12439638] [PUBMED:16817756] [PUBMED:16845885] [PUBMED:10051305] [PUBMED:10904843]
p53 signaling pathway [NCBI:83055] [KEGG:hsa04115] [PUBMED:16557269] [PUBMED:10714958] [PUBMED:12505356] [PUBMED:16915296] [PUBMED:16697662] [PUBMED:15116721] [PUBMED:11313928] [PUBMED:11747320] [PUBMED:17409411] [PUBMED:15838523]
p75 NTR receptor-mediated signalling [NCBI:1269445] [REACTOME:R-HSA-193704] [PUBMED:16699811] [PUBMED:16939974] [PUBMED:12671646]
p75(NTR)-mediated signaling [NCBI:138019] [Pathway Interaction Database:p75ntrpathway] [PUBMED:14673001] [PUBMED:14593116] [PUBMED:10545116] [PUBMED:11729324] [PUBMED:16252010] [PUBMED:11756426] [PUBMED:12414813] [PUBMED:2157470] [PUBMED:11777929] [PUBMED:1547788] [PUBMED:10764727] [PUBMED:8614802] [PUBMED:14960584] [PUBMED:12376548] [PUBMED:11756498] [PUBMED:8079174] [PUBMED:16498402] [PUBMED:15051733] [PUBMED:12682012] [PUBMED:14638693] [PUBMED:14966521] [PUBMED:9915784] [PUBMED:11487608] [PUBMED:10485890] [PUBMED:16630834] [PUBMED:11312266] [PUBMED:10985348] [PUBMED:11244088] [PUBMED:6093111] [PUBMED:10595511] [PUBMED:14985763] [PUBMED:12097334] [PUBMED:15548667] [PUBMED:15470142] [PUBMED:11279271] [PUBMED:8878481] [PUBMED:12422217] [PUBMED:15987945] [PUBMED:15668238] [PUBMED:10433815] [PUBMED:12692556] [PUBMED:2025430] [PUBMED:15930396] [PUBMED:11278287] [PUBMED:12034707]