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full name
mutY DNA glycosylase

synonyms
CYP2C, MYH, MUTYH, ENSG00000132781

HGNC
HGNC:7527

Entrez Gene
Gene:4595

ENSEMBL
ENSG00000132781

location
chr: 1
start: 45794914
stop: 45806142
strand: -

OMIM
OMIM:604933: MUTYH (Autosomal recessive inheritance)
OMIM:608456: Adenomas, multiple colorectal
OMIM:132600: Colorectal adenomatous polyposis, autosomal recessive, with pilomatricomas
OMIM:613659: Gastric cancer, somatic

transcripts
NM_001048171.1
NM_012222.2
NM_001128425.1
NM_001048173.1
NM_001048172.1
NM_001048174.1

pathways
Base Excision Repair [NCBI:1270351] [REACTOME:R-HSA-73884] [PUBMED:11937636] [PUBMED:10583946]
Base excision repair [NCBI:83043] [KEGG:hsa03410] [PUBMED:17893748] [PUBMED:11436317] [PUBMED:17337257] [PUBMED:21665970]
Base-Excision Repair, AP Site Formation [NCBI:1270352] [REACTOME:R-HSA-73929] [PUBMED:10583946] [PUBMED:11937636]
Cleavage of the damaged purine [NCBI:1270355] [REACTOME:R-HSA-110331] [PUBMED:8016081] [PUBMED:10583946]
DNA Repair [NCBI:1270350] [REACTOME:R-HSA-73894] [PUBMED:10583946] [PUBMED:23175119]
Depurination [NCBI:1270353] [REACTOME:R-HSA-73927] [PUBMED:8900285] [PUBMED:9724657]
Displacement of DNA glycosylase by APEX1 [NCBI:1270360] [REACTOME:R-HSA-110357] [PUBMED:9724657]
Recognition and association of DNA glycosylase with site containing an affected purine [NCBI:1270354] [REACTOME:R-HSA-110330] [PUBMED:8900285] [PUBMED:9724657]
Resolution of Abasic Sites (AP sites) [NCBI:1270359] [REACTOME:R-HSA-73933] [PUBMED:11601988] [PUBMED:15260972] [PUBMED:17395641] [PUBMED:19329425] [PUBMED:9804798] [PUBMED:15556996] [PUBMED:9214649] [PUBMED:7608159] [PUBMED:11440997] [PUBMED:15871698] [PUBMED:9207062] [PUBMED:16982218] [PUBMED:8978692]